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Franziska Knolle

@franziskaknolle.bsky.social
334 followers 312 following 55 posts

Cognitive, clinical, computational neuroscience: I study how we understand language and make decisions, and what happens in the brain if things go wrong. franziskaknolle.com www.tum.de www.mri.tum.de

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Reposted by Franziska Knolle
The vOICe vision BCI 🧠🇪🇺 @seeingwithsound.bsky.social · 02/10/2026
Tensor decomposition reveals discrete cortical reorganization under graded propofol anesthesia www.frontiersin.org/journals/neu... Circumstantial evidence that qualia of perception (vision, hearing, ...) will also turn out to involve discrete spatiotemporal (spatiospectral) brainwave constellations?
Decomposition and evolutionary profiles of propofol-induced nonlinear coupling.
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Reposted by Franziska Knolle
Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 30/09/2026
Our multilayer MEG paper is out today in Nature Communications: depth-resolved laminar inference in humans 🧠#neuroskyence www.nature.com/articles/s41...
nature.com
Multilayer MEG source modelling enables depth-resolved laminar inference in humans - Nature Communications
Researchers developed a multilayer MEG framework that estimates activity across cortical depth non-invasively. Simulations and three human datasets show when reliable laminar inference is possible, en...
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Reposted by Franziska Knolle
Christoph Strauch @cstrauch.bsky.social · 02/10/2026
How much of a risk are LLM-generated bots for online behavioral experiments? We present results of an entirely natural language prompt-generated agent, capable of absolving any of the 26 experiments we tested it on. Most tasks are passed with data that can pass as human osf.io/preprints/ps... (1/)
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Franziska Knolle @franziskaknolle.bsky.social · 28/09/2026
🚨 Registration closes September 30! We have an amazing programme! So join us for *the* meeting on voices, visions, presences & more - with 5 stellar keynotes!! We are looking forward to seeing you in Munich! 🧠🥨 Register here: docs.google.com/forms/d/e/1F...
docs.google.com
ICHR and ECHR Satellite Meeting 2026, Munich, Germany - REGISTRATION
We are pleased to welcome you to the 2026 ICHR and ECHR Satellite Meeting, hosted by the Technical University of Munich (TUM), Klinikum rechts der Isar, in Munich, Germany, from 19–21 October 2026. Pl...
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Reposted by Franziska Knolle
Imaging Neuroscience @imagingneurosci.bsky.social · 24/09/2026
New paper in Imaging Neuroscience by David Halpern and Todd Gureckis: Getting blood from a stone: Improving brain–behavior inferences without brain data doi.org/10.1162/IMAG...
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Reposted by Franziska Knolle
Nuno Busch @nunobusch.bsky.social · 18/09/2026
🎁 Best birthday present this week was finally finishing and preprinting this big project: Together with @thorstenpachur.bsky.social, we investigated how loss aversion in risky choice is affected by how we learn about our options. 📖 Full-text here: lnkd.in/eKu2AEwB
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Reposted by Franziska Knolle
Earl K. Miller @earlkmiller.bsky.social · 16/09/2026
A review of mathematical models of ephaptic coupling, how neurons can influence each other through electrical field effects. link.springer.com/article/10.1... #neuroscience
link.springer.com
Ephaptic coupling between neurons: a systematic review of mathematical models - BMC Bioinformatics
Background Ephaptic coupling is a relatively underexplored mechanism of neuronal interaction mediated by perturbations of the extracellular electric potential without the formation of conventional che...
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Reposted by Franziska Knolle
Nature Human Behaviour @nathumbehav.nature.com · 15/09/2026
Complexity is a unified cognitive kind
dlvr.it
Complexity is a unified cognitive kind
Nature Human Behaviour, Published online: 15 September 2026; doi:10.1038/s41562-026-02502-8Boger and Firestone show that humans possess a domain-general, cross-modal representation of complexity.
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Reposted by Franziska Knolle
Tom Kash @superkash.bsky.social · 15/09/2026
new paper out, led by @jobeneuro.bsky.social , exploring 5HT dynamics in cingulate and central amygdala, and how a history of alcohol consumption changes them! www.nature.com/articles/s41...
nature.com
Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption - Neuropsychopharmacology
Neuropsychopharmacology - Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption
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Reposted by Franziska Knolle
Ondrej Zika @ondrejzika.bsky.social · 15/09/2026
🚨 💫 💥 Interested in PhD / Postdoc opportunities in computational psychiatry / cognitive neuroscience? My lab at University College Dublin 🇮🇪 is currently accepting expressions of interest for internally funded PhD/Postdoc applications for positions starting in September 2027 (!). 1/
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Reposted by Franziska Knolle
Nature Human Behaviour @nathumbehav.nature.com · 26/08/2026
Mentalizing and heuristics as distinct cognitive strategies in human teaching
dlvr.it
Mentalizing and heuristics as distinct cognitive strategies in human teaching
Nature Human Behaviour, Published online: 26 August 2026; doi:10.1038/s41562-026-02540-2Harootonian et al. find that people switch between effortful, tailored teaching and easier, simple shortcuts, favouring shortcuts even when unhelpful. Prompting participants to reflect on learners’ limitations restores effective, personalized instruction.
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Franziska Knolle @franziskaknolle.bsky.social · 26/08/2026
🚨Here is an interesting manipulation of the BART 🎈💥 which explores reversals of risk contingencies! Very useful also for clinical work such as schizophrenia research! Fantastic work led by @zachtefertiller.bsky.social ! Congratulations to Zach’s first PhD preprint!! 🎉
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Reposted by Franziska Knolle
Tobias Hauser @tobiasuhauser.bsky.social · 14/07/2026
Progress in Computational Psychiatry is is slowed down substantially because researchers (clinicians, cognitive neuroscientists, etc) lack the training in computational modelling and many studies dont follow the best practices in modelling. How can we change this? We've built the CPM toolbox:
static.klipy.com
Dancing Robot Celebration
ALT: Dancing Robot Celebration
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Reposted by Franziska Knolle
Helen Blank @helenblank.bsky.social · 26/08/2026
Very much looking forward to our Network symposium on predictive processing in Bochum this October: predcommlab.github.io/symposium-20...
predcommlab.github.io
Predictive Processing Network Symposium 2026
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Reposted by Franziska Knolle
Trends in Neurosciences @cp-trendsneuro.bsky.social · 25/08/2026
'Beyond Bayesian integration: how meaning shapes placebo effects' by Katja Wiech, Falk Eippert, Karin Jensen, Lene Vase & Ulrike Bingel @ulrikebingel.bsky.social www.cell.com/trends/neuro...
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Reposted by Franziska Knolle
Earl K. Miller @earlkmiller.bsky.social · 24/08/2026
A New Framework for How the Brain Compresses Our Noisy World www.quantamagazine.org/a-new-framew... An updated view of categorization reflects the modern understanding that the nervous system is more of a prediction engine than a filing cabinet. #neuroscience
quantamagazine.org
A New Framework for How the Brain Compresses Our Noisy World | Quanta Magazine
An updated view of categorization reflects the modern understanding that the nervous system is more of a prediction engine than a filing cabinet.
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Reposted by Franziska Knolle
Nico Schuck @nicoschuck.bsky.social · 24/08/2026
I enjoyed writing this piece for The Transmitter. AI is a seismic change for science. What we make of it is up to us, but it’s a decision we can only make collectively. I hope more labs, and the field at large, will engage in finding a shared view of how we want to use AI.
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Franziska Knolle @franziskaknolle.bsky.social · 24/08/2026
🚨Registration is now open for the 2026 ICHR & ECHR Satellite Meeting in Munich, 19–21 October! Deadline: 30 September 2026 Programme and registration details: sites.google.com/view/echrich... We hope to see many of you in Munich in October!🥨🧠 @theichr.bsky.social&@echrhallucinations.bsky.social
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Reposted by Franziska Knolle
David Roberts @volts.wtf · 23/08/2026
I hope everyone caught this Lancet study confirming that Elon Musk & DOGE are responsible for genocidal levels of suffering & death.
thelancet.com
Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030: a retrospective impact evaluation and forecasting analysis
USAID funding has significantly contributed to the reduction in adult and child mortality across low-income and middle-income countries over the past two decades. Our estimates show that, unless the a...
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Reposted by Franziska Knolle
Tatiana Engel @engeltatiana.bsky.social · 19/08/2026
Difficult decisions take time, but can we keep all accumulated evidence in mind long enough to make better choices? We find that working-memory limitations constrain decision-making, and these effects are modulated by dopamine. biorxiv.org/content/10.6... bioRxiv out with Cina Aghamohammadi et al.
biorxiv.org
Working memory limitations and dopamine modulation in probabilistic reasoning
Difficult decisions require gathering evidence over extended periods, placing demands on working memory. Yet, how working memory limitations affect decision-making remains largely unknown. We trained ...
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Reposted by Franziska Knolle
Benjamin Straube @straubeb.bsky.social · 26/07/2026
Now available in Trends Open: How do expectations shape actions? I introduce the ExSA framework, integrating perspectives from motor control, decision-making, predictive processing, and clinical neuroscience Read here: www.cell.com/trends-open/... #Psychology #MotorControl #PredictiveProcessing
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Reposted by Franziska Knolle
Alex Pike @alexandrapike.bsky.social · 28/07/2026
New paper alert! In this paper we were interested to formally test some of the assumptions made by computational psychiatrists - assumptions about parameter recoverability, reliability and validity. www.cambridge.org/core/journal...
cambridge.org
The recoverability, reliability, and generalizability of reward processing parameters and relation to mental health symptoms | Psychological Medicine | Cambridge Core
The recoverability, reliability, and generalizability of reward processing parameters and relation to mental health symptoms - Volume 56
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Reposted by Franziska Knolle
Reza Shadmehr @rezashadmehr.bsky.social · 28/07/2026
If an action results in error, each neuron requires an individualized teaching signal that guides change in its output. This is the credit assignment problem of learning. Are there neurons in the brain that can compute such a sophisticated teaching signal? Yes. www.biorxiv.org/content/10.6...
biorxiv.org
Climbing fibers encode the gradient of a loss function for the cerebellum
Neurons in the brain are often many synapses away from motoneurons, yet if a movement results in error, each distant neuron needs a teacher that considers its specific contribution to production of th...
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Reposted by Franziska Knolle
Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 29/07/2026
Why do people in #Denmark living with #schizophrenia do better than those living in other countries? The blog, from @ricardotwumasi.bsky.social), explores work which followed more than 65,000 People in Denmark diagnosed with schizophrenia for up to ten years. www.kcl.ac.uk/why-do-peopl...
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Helen Barron @helencbarron.bsky.social · 28/07/2026
***New preprint from the lab*** showing “Generative replay across hippocampal-neocortical circuits”. In sleep we show spiking sequences in V1 (sensory neocortex!) that represent information that has not been directly experienced www.biorxiv.org/content/10.6... @bndu.ox.ac.uk @ndcnoxford.bsky.social
biorxiv.org
Generative replay across hippocampal-neocortical circuits
To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...
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Reposted by Franziska Knolle
jsPsych @jspsych.org · 26/07/2026
Response duration tracking is now an option in jsPsych 8.3.0. Decide whether to trigger responses on key press (current default) or wait for key release to get both initial response time and response duration. We handle edge cases like multiple keys being pressed and tabbing away from the browser.
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Reposted by Franziska Knolle
Aaron Sojourner @aaronsojourner.org · 25/07/2026
Admirable clarity @science.org
The Trump administration hates academic science funding, full stop. They hate where that money goes, and they hate who it goes to. They want to keep all that money for themselves, to hand out to favored cronies who can help them get elected and to steer yet more money and more power back into their hands.

That’s it. That’s the story
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Reposted by Franziska Knolle
Barack Obama @barackobama.bsky.social · 24/07/2026
Got the chance to see these talented players in action today! It was great having the @wnba.com at Home Court at the Obama Presidential Center for All-Star Weekend. 🏀
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Reposted by Franziska Knolle
cjl2007.bsky.social @cjl2007.bsky.social · 22/06/2026
Happy to share that our paper on objective quality assessment for "precision" fMRI is now out in @cp-neuron.bsky.social A recap of what it does, what's new since the preprint, and code you can run on your own data. cell.com/neuron/fullt...
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Reposted by Franziska Knolle
Earl K. Miller @earlkmiller.bsky.social · 12/07/2026
Function is not tied to specific brain structures or time scales. The brain is not just a set of parts that each “do their own job”. Instead, networks are multifunctional and active across different speeds simultaneously. doi.org/10.1073/pnas... #neuroscience
doi.org
Shared spatial and temporal principles govern connectome dynamics across timescales | PNAS
While the brain processes information at various speeds, little is known about how the functional connectome can concurrently support multiple spee...
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Reposted by Franziska Knolle
Roxana Zeraati @roxana-zeraati.bsky.social · 07/07/2026
Our paper "Neural timescales from a computational perspective" is finally out in @natneuro.nature.com: www.nature.com/articles/s41... We discuss how computational models and methods can distill empirical observations on neural timescales into quantitative, testable theories of brain computation.
nature.com
Neural timescales from a computational perspective - Nature Neuroscience
This review integrates computational approaches to provide a unified view on how data analysis methods, biophysical mechanistic models and machine learning approaches can help to uncover the origins a...
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Philipp Kanske @kanske.bsky.social · 13/07/2026
Wir suchen Verstärkung - job alert 🎺 PhD- oder PostDoc-Stelle an der TU Dresden im Bereich der klinisch-sozialen Neurowissenschaft mit Mitarbeit am @trr393.bsky.social und in der Lehre. Text me if interested. - Please share - @biodgps-dgpa.bsky.social @tudresden.bsky.social
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The vOICe vision BCI 🧠🇪🇺 @seeingwithsound.bsky.social · 13/07/2026
Synergistic entrainment: a multiscale neurodynamic framework for closed-loop cross-modal neuromodulation link.springer.com/article/10.1... Similarly, opt for timed hybrid use of brain implant and sensory substitution?
link.springer.com
Synergistic entrainment: a multiscale neurodynamic framework for closed-loop cross-modal neuromodulation - Cognitive Neurodynamics
The brain’s higher cognitive functions rely on the dynamic integration of multimodal information, supported by coordinated neural oscillations. However, current neuromodulation approaches often fail t...
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Reposted by Franziska Knolle
Blake Richards @tyrellturing.bsky.social · 07/07/2026
For a long time I felt like there was a hesitation in neuroscience to ascribe anything like a planning function to the various "replay" events we see in the hippocampus, but I think this is rapidly changing. Here's another new entry in human epilepsy patients: www.nature.com/articles/s41... 🧠📈 🧪
nature.com
Human hippocampal ripples coordinate planning sequences and compositional representations in neocortex - Nature Neuroscience
Human hippocampal ripples and replay interact with the prefrontal cortex to update mental representations online, letting the brain compositionally combine familiar elements in new ways for flexible p...
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The vOICe vision BCI 🧠🇪🇺 @seeingwithsound.bsky.social · 07/07/2026
Deep learning reveals cross-modal neural representations of auditory and visual mental imagery in MEG journals.physiology.org/doi/abs/10.1... "findings advance our understanding of cross-modal mental imagery and point toward more flexible and personalized approaches in #BCI design." #neuroscience
journals.physiology.org
Deep Learning Reveals Cross-Modal Neural Representations of Auditory and Visual Mental Imagery in MEG | Journal of Neurophysiology | American Physiological Society
Mental imagery provides a unique window into the brain’s ability to internally simulate sensory experiences, offering valuable insights for both cognitive neuroscience and brain-computer interface (BC...
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Reposted by Franziska Knolle
womensartbluesky.bsky.social @womensartbluesky.bsky.social · 06/07/2026
Photographer Chantal Pinzi's photogragraphic series of women skateboarders around the world #WomensArt #Monday
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Franziska Knolle @franziskaknolle.bsky.social · 06/07/2026
Fantastic work by @prithasen.bsky.social on youth mental health and how to cluster individuals longitudinally and cross-sectionally in a meaningful way to reveal persistent alterations in cognition and brain morphology! 🧠🤩
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Pritha Sen @prithasen.bsky.social · 06/07/2026
🚨 Excited to share our latest preprint with my supervisor @franziskaknolle.bsky.social We describe a way to measure transdiagnostic mental-health burden in adolescents and examine how higher burden is associated with differences in cognition and brain structure. www.medrxiv.org/content/10.6...
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Earl K. Miller @earlkmiller.bsky.social · 05/07/2026
Analog computation is real, and your brain can take advantage of it. This chip does something similar, using natural electrical drift in its hardware to perform efficient analog computation. doi.org/10.1126/scie... #neuroscience
doi.org
A sub–10-millisecond neural dynamical system based on phase-change memristors
High-fidelity geometry for physical-world modeling demands real-time, dense, and differentiable deformation fields on manifolds. Neural dynamical systems (NDSs) using adaptive stepsize integration wit...
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Earl K. Miller @earlkmiller.bsky.social · 05/07/2026
Individual variability of neural computations underlying flexible decisions www.nature.com/articles/s41... #neuroscience
nature.com
Individual variability of neural computations underlying flexible decisions - Nature
Behavioural experiments to study decision-making in response to context-dependent accumulation of evidence provide testable models that are consistent with the heterogeneity in neural signatures among...
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Reposted by Franziska Knolle
JAMA Psychiatry @jamapsychiatry.com · 05/07/2026
Targeted psychological and psychosocial interventions for #Schizophrenia, including avatar therapy, reduced the severity of #AuditoryHallucinations with small to medium effects and high acceptability. ja.ma/4wsgrIb
Table 3: Meta-Analytic Results on Dropout Analyses. It displays statistics like risk ratio and proportions for treatment and study dropouts in intervention (IG) and control groups (CG), including k, I²%, I² P value, effect size (with 95% CI), and effect P values.
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Takaki Komiyama @takakikomiyama.bsky.social · 05/07/2026
Our new paper is out in Nature, congrats to Sonja et al.! An excellent collab with Irina Dudanova's group. We promoted neuroplasticity to improve behavior in a mouse model of a neurodegenerative disease. www.nature.com/articles/s41...
nature.com
Restoring cortical disinhibition improves Huntington’s disease phenotypes - Nature
In a mouse model of Huntington’s disease, targeted modulation of neuronal activity restores network function and improves motor deficits.
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Alon Baram @alonbaram.bsky.social · 29/06/2026
How does the human brain extract abstract structure from experience? We show that sensory-independent relational representations emerge in mPFC over several days. Work with @mgarvert.bsky.social and @behrenstimb.bsky.social now out in @currentbiology.bsky.social: www.cell.com/current-biol...
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MIT Siegel Family Quest for Intelligence @mit-sqi.bsky.social · 01/07/2026
MIT researchers are studying the brain's language network — and their recent findings are surprising. @evfedorenko.bsky.social @coltoncasto.bsky.social @benlipkin.bsky.social news.mit.edu/2026/brain-l...
news.mit.edu
The brain’s language network is more extensive than previously thought
Using functional magnetic resonance imaging (fMRI) data from more than 700 people, MIT researchers identified 17 brain regions outside of the canonical language-processing centers that are also involv...
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Reposted by Franziska Knolle
The vOICe vision BCI 🧠🇪🇺 @seeingwithsound.bsky.social · 02/06/2026
Review article: Restoring vision and touch with cortical microstimulation www.nature.com/articles/s44... by @giacomovalle.bsky.social et al.; #BCI #NeuroTech #blindness
nature.com
Restoring vision and touch with cortical microstimulation - Nature Reviews Bioengineering
Cortical sensory prostheses aim to restore vision and touch by stimulating primary visual and somatosensory cortices. This Review examines shared challenges and principles underlying visual and somato...
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Manoj Doss not exist @manojdoss.bsky.social · 01/07/2026
Check out our recent review on how psychedelics don’t simply enhance cognitive flexibility by Raquel Kosted, @drjjdonegan.bsky.social, Josh Cisler, and Greg Fonzo. www.sciencedirect.com/science/arti... 1/12
sciencedirect.com
Psychedelics do not always enhance cognitive flexibility: The potential role of time-varying effects on reward learning processes
Although research on psychedelics (hallucinogenic serotonin 2 A or 5-HT2A agonists) has shown initial promise in ameliorating a range of psychiatric c…
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Daryl Cameron @dcameron.bsky.social · 19/06/2026
Watch the whole thing for an empathetic vision of America. www.youtube.com/watch?v=waUj...
youtube.com
FULL SPEECH: Michelle Obama at opening of Barack Obama Presidential Center
YouTube video by ABC News
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Reza Shadmehr @rezashadmehr.bsky.social · 19/06/2026
www.youtube.com/watch?v=IW-6...
youtube.com
How the Brain Predicts the Future | Prof. Reza Shadmehr
YouTube video by Wandering Thoughts
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Marc L Seal @parkvillegeek.bsky.social · 19/06/2026
Mapping the neuronal building blocks of human language with language models | Nature www.nature.com/articles/s41...
nature.com
Mapping the neuronal building blocks of human language with language models - Nature
Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the...
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