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Fitz-James Lab

@fitz-james-lab.bsky.social
2.2K followers 1.1K following 37 posts

Molecular biology lab based at the Department of Biology, University of Oxford. Researching insect epigenetics and epigenetic inheritance.

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Fitz-James Lab @fitz-james-lab.bsky.social · 15h
🧪A pleasure to have hosted the first meeting of the Oxford Chromatin Club with @mariekewens.bsky.social yesterday! Great talks from Hoa Vo (Physics) on CMG progression and @joyjoychoi.bsky.social (@oxfordbiochemistry.bsky.social) showing the incredible CryoET work from her new preprint (link below).
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Charlène Boumendil (She/Her) @charleneboumendil.bsky.social · 20/03/2026
We are looking for a new group leader to join the IGH (Montpellier, France). I can’t wait to meet my future colleague! Apply :-) More infos here: igh.cnrs.fr/join-igh-as-...
igh.cnrs.fr
Join IGH as Group Leader - IGH
The Institute of Human Genetics invites applications for a Principal Investigator position in its main research areas. Read more...
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Takashi Akera Lab @takashiakeralab.bsky.social · 22/03/2026
We are hiring POSTDOC now!🚨please repost! Fully-funded 5-year position 👩🏻‍🔬👨‍🔬🧬Looking forward to your application!✉️
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Rob Klose @robklose.bsky.social · 13/03/2026
We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).
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Fena Ochs @fenaochs.bsky.social · 02/01/2026
We are looking for a Postdoc at the Center for Gene Expression in Copenhagen. Deadline for applications is the 11th of January. If you are interested in 3D chromatin, SMC complexes, and super-resolution microscopy, join us. www.nature.com/naturecareer...
nature.com
Postdocs at Center for Gene Expression in Department of Cellular and Molecular Medicine - Copenhagen, Hovedstaden (DK) job with University of Copenhagen | 12849488
We are looking for 2 or more highly motivated postdocs interested in ribosome biology, 3D chromatin organisation, or regulation of protein turnove...
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Ben Carty @bencarty.bsky.social · 27/11/2025
Very proud to have our latest work now online in @natsmb.nature.com. A wonderful team effort across the centromere community, across @jansenlab.bsky.social @naltemose.bsky.social @dfachinetti.bsky.social and Giunta labs. Happy reading! 1/4 www.nature.com/articles/s41...
nature.com
Heterochromatin boundaries maintain centromere position, size and number - Nature Structural & Molecular Biology
Carty et al. identify the H3K9 methyltransferases that restrict the size and position of the centromere protein A chromatin domain, maintaining functional centromeres.
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Mark A. Hanson @hansonmark.bsky.social · 15/11/2025
WE ARE RECRUITING PHD STUDENTS!!! We have three(!) funded PhD studentships advertising presently. If any of these are of interest, please reach out! Thread below with links to more information on each project. #Drosophila #Evolution #Immunity #SelfishGene #Aphids Thread with links below 🧵 1/4
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Fitz-James Lab @fitz-james-lab.bsky.social · 18/10/2025
It’s been a big month for the lab! We’ve gone from just me to six in as many weeks. I’m so excited to embark on this new chapter with these wonderful people, and I’m looking forward to the exciting science 🧪we’ll be doing together in the new Life and Mind Building @biology.ox.ac.uk #epigenetics
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Fitz-James Lab @fitz-james-lab.bsky.social · 17/09/2025
Excited to be presenting my work today at @biochemsoc.bsky.social event Transcription and Chromatin UK!
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Fitz-James Lab @fitz-james-lab.bsky.social · 24/07/2025
Last day of #SMBE2025 in Beijing! It was a real pleasure to talk about epimutation on Tuesday and to get to know lots of new researchers and their exciting work!
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Fitz-James Lab @fitz-james-lab.bsky.social · 19/07/2025
Traveling to Beijing for @official-smbe.bsky.social #SMBE 2025. I have both a talk and a poster on Tuesday on different aspects of epigenetic inheritance. Stop by if you’re there!
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Duncan Sproul @sproullab.bsky.social · 03/07/2025
🚨Fantastic PhD opportunity for Autumn 2025 with our colleague Rebekah Tillotson @uoe-igc.bsky.social, asking whether ATRX syndrome is treatable: sidb.org.uk/phds/tillots... Please share 🙏 #epigenetics #raregeneticdisease #chromatinopathies
sidb.org.uk
SIDB
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Biochemical Society @biochemsoc.bsky.social · 26/06/2025
Taking place on 17-19 September 2025, Transcription and Chromatin UK will showcase cutting-edge research and is a ‘mustattend’ for anyone within the transcription and epigenetics community🧪. Register now: www.eventsforce.net/biochemsoc/2...
Transcription and Chromatin UK
Manchester, UK
17-19 September 2025
Earlybird deadline: 17 July 2025
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Alessandro Costa @costalaboratory.bsky.social · 20/06/2025
Postdoc positions open in my lab (Francis Crick Institute) to study 1. initiation of DNA replication. 2. chromatin replication/epigenetic inheritance. Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists. Deadline 3 August 2025. crick.wd3.myworkdayjobs.com/External/job...
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Fitz-James Lab @fitz-james-lab.bsky.social · 20/06/2025
Great opportunity in a fun lab / cool city!
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Magdalena Skipper @magdalenaskipper.bsky.social · 16/06/2025
From today, every paper submitted to Nature -if published - will be accompanied by peer reviewers comments & authors rebuttal. We started the trial in 2020; we now want to open up the review process & showcase its role in shaping & improving papers 🧪 #AcademicSky www.nature.com/articles/d41...
nature.com
Transparent peer review to be extended to all of Nature’s research papers
From today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science.
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Fitz-James Lab @fitz-james-lab.bsky.social · 05/06/2025
A nice short reminder to be wary of the press overstating scientific claims link.springer.com/article/10.1...
link.springer.com
Clarifying the public misrepresentation of transgenerational epigenetic inheritance - Theoretical Medicine and Bioethics
Theoretical Medicine and Bioethics -
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Fitz-James Lab @fitz-james-lab.bsky.social · 23/05/2025
🚨Job Alert🚨 We are looking for a technician to join us in Oxford @biology.ox.ac.uk to study epigenetics and vibration-sensing: my.corehr.com/pls/uoxrecru... The work will be varied: Arthropod culture 🕷️🪰 Lab work (DNA/RNA extraction, sequencing library preparation…) Apply by Mon 23 June 🧪
my.corehr.com
'
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Berta Verd @bertaverd.bsky.social · 19/05/2025
Experimental embryology postdoc available in my lab at the @biology.ox.ac.uk @ox.ac.uk working on the evolution of vertebral counts. Reach out if you’re passionate about EvoDevo, enjoy lab work and microscopy and are into or could get into cichlid fishes. Deadline on the 16th June. Please share!
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Fitz-James Lab @fitz-james-lab.bsky.social · 09/05/2025
Very cool paper combining two of my favourite things: phylogeny and genome organisation
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Fly Journal @fly-journal.bsky.social · 17/04/2025
Fly journal is now on BlueSky! The world’s only academic journal dedicated to research on Drosophila & cognate insects. A fully open-access journal that combines rapid publication with high standards of peer-review. For further info and how to submit your work, see the link.
tandfonline.com
Fly
Open access research on Drosophila developmental/evolutionary biology, organogenesis, neurobiology, circadian rhythms, learning & memory, sex determination
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Flora Paldi @fpaldi.bsky.social · 14/04/2025
Our new review in @cp-trendscellbio.bsky.social is now online! We discuss the connection between the epigenome, 3D genome folding, gene expression and cellular memory, specifically in loop extrusion-independent contexts.
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Sheppard Lab @sheppardlab.bsky.social · 07/04/2025
TWO postdoc positions in Computational Microbiology and/or biochemistry. Join our interdisciplinary group in the new Life and Mind Building @OxfordBiology, @UniofOxford, @IneosOxford Please apply and share this post: www.jobs.ac.uk/job/DMP641/p...
jobs.ac.uk
Postdoctoral Research Associate at University of Oxford
Discover Postdoctoral Research Associate jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.
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Antoine Molaro @antoinemolaro.bsky.social · 31/03/2025
Hello World! Are you passionate about epigenomics and evolution 🧪🧬🐭🐵 ? Are you looking for a postdoc in a stimulating and inclusive environment ? Look no further... We are seeking creative postdocs for our ERC project EvoEpi @igred.fr ! 👇Details👇 tinyurl.com/PostdocEvoEp... Repost are appreciated
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Fitz-James Lab @fitz-james-lab.bsky.social · 15/03/2025
Something to ponder when considering which journal to submit to. Society owned journals are an important source of income for the community.
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Fitz-James Lab @fitz-james-lab.bsky.social · 12/03/2025
1/10 Excited to share our recent work with @psarkies.bsky.social out in Open Biology today. We follow up on a case of Drosophila epigenetic inheritance and find no evidence of sRNA involvement. Plus a surprising result of interest to Drosophilists! royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org
Polycomb-mediated transgenerational epigenetic inheritance of Drosophila eye colour is independent of small RNAs | Open Biology
Transgenerational epigenetic inheritance (TEI) describes the process whereby distinct epigenetic states are transmitted between generations, resulting in heritable gene expression and phenotypic diffe...
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Alicia Hidalgo Lab @aliciahidalgolab.bsky.social · 01/03/2025
Postdoc opportunity in UK, Wellcome funded, 3 years, to investigate neurogenetics underlying how the brain changes throught life: plasticity vs degeneration. Drosophila, imaging, behaviour. Candidates of all nationalities welcome. Application deadline 19 March. Pls repost. #Drosophila #postdoc #job
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Peter Sarkies @psarkies.bsky.social · 27/02/2025
Postdoc or PhD working on C. elegans? Interested in applying C. elegans techniques to understand the astonishing world of epigenetics in parasitic nematodes? Apply to our Wellcome Trust funded postdoc position, joint between my lab in Oxford and Mark Viney's in Liverpool: tinyurl.com/5y6cpvcv
tinyurl.com
Job Specification
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Fitz-James Lab @fitz-james-lab.bsky.social · 20/02/2025
Wow! Incredibly grateful to Jessica Hawes and Alyson Ashe for their very kind preview of our paper for the current issue of Mol Cell! @cellpress.bsky.social www.cell.com/molecular-ce...
cell.com
Moving epigenetic inheritance into the space age: Evidence that 3D genome organization is required for the establishment of epigenetic memory
In this issue, Fitz-James et al. use genetic manipulations to show that transient interchromosomal contacts between distant regulatory elements, mediated by the transcription factor GAF, can initiate ...
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Fitz-James Lab @fitz-james-lab.bsky.social · 19/02/2025
Still two weeks left to apply to join the lab in Oxford @biology.ox.ac.uk for an exciting project on #epigenetic inheritance in #Drosophila !
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Fitz-James Lab @fitz-james-lab.bsky.social · 18/02/2025
Very excited to be setting up my lab @biology.ox.ac.uk and looking forward to growing the team in the coming years!
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Epigenetics Podcast @epigeneticspod.bsky.social · 17/02/2025
In the most recent episode we talked with Giacomo Cavalli from the IHG in Montpellier about his work on critical aspects of epigenetic regulation, particularly the role of Polycomb proteins and chromatin architecture. #podcast #epigenetics Listen here: buff.ly/41eRD9E
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The Groth lab @grothlab.bsky.social · 12/02/2025
🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
tinyurl.com
6 Postdoctoral and PhD positions in Center for Epigenetic Cell Memory (EpiC)
The Center for Epigenetic Cell Memory (EpiC) is a new Center of Excellence that will be established based on funding by the Danish National Research Foundation.
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Fitz-James Lab @fitz-james-lab.bsky.social · 11/02/2025
I can highly recommend a great programme to come work at a very welcoming place!
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Berta Verd @bertaverd.bsky.social · 05/02/2025
I am recruiting an #ERC funded PostDoc to work on the evolution of vertebral counts in cichlids. This is an experimental project & will be looking for candidates with experience generating reporter lines, live-imaging and experimental embryology. Application deadline: 25th Feb. tinyurl.com/33jbu8fa
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Fitz-James Lab @fitz-james-lab.bsky.social · 05/02/2025
We are looking for a post-doc to join us in Oxford @biology.ox.ac.uk to study epigenetic inheritance! The project will use Cut&Run and RNA-seq to map and track new epimutations as they arise in Drosophila populations across multiple generations. Feel free to share! my.corehr.com/pls/uoxrecru...
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Science of the Times Podcast @scienceofthetimes.bsky.social · 04/02/2025
Our first recording is underway! Watch this space for details, folks. @sykhalid.bsky.social @timcoulson.bsky.social
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Ivana Jerkovic @ivana-jerkovic.bsky.social · 31/01/2025
We seek a bioinformatician to join our group at the College de France, Paris. If you like genomics, 3D genome organization, gene regulation, and development check out the offer and get in touch!
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Fitz-James Lab @fitz-james-lab.bsky.social · 10/01/2025
Pour les intéressés francophones, un résumé de notre article récent dans Molecular Cell: www.insb.cnrs.fr/fr/cnrsinfo/...
insb.cnrs.fr
L’ADN maître de l’origami : un nouveau mécanisme d’héritage biologique
Dans un article publié dans Molecular Cell, des scientifiques ont découvert comment l’organisation tridimensionnelle de l’ADN dans nos cellules influ
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Lars Jansen Lab @jansenlab.bsky.social · 17/12/2024
Join our team www.jansenlab.org as a @wellcometrust.bsky.social -funded postdoctoral fellow and help us discover how chromatin at human centromeres is formed and inherited. Position now open at @oxfordbiochemistry.bsky.social! See: my.corehr.com/pls/uoxrecru... for details!
https://www.jansenlab.org/home
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Chris Jiggins @chrisjiggins.bsky.social · 18/12/2024
Join us in Cambridge! This evolutionary genomics professorship (lecturer/reader level) has an emphasis on introgression and gene flow. If you study any aspect of evolutionary genomics then please apply! www.jobs.cam.ac.uk/job/49389/
jobs.cam.ac.uk
Associate Professor / Professor of Evolutionary Genomics - Job Opportunities - University of Cambridge
Associate Professor / Professor of Evolutionary Genomics in the Department of Genetics at the University of Cambridge.
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Fitz-James Lab @fitz-james-lab.bsky.social · 11/12/2024
And here is a write-up of the study on the Departmental website @oxfordbiochemistry.bsky.social www.bioch.ox.ac.uk/article/dna-...
bioch.ox.ac.uk
DNA origami: a new frontier in epigenetic inheritance across generations
In a collaboration between two labs spanning both sides of the English Channel, scientists have discovered a new way in which the organisation of DNA within our cells affects genes for generations
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Fitz-James Lab @fitz-james-lab.bsky.social · 11/12/2024
Excited to share my new paper implicating the 3D genome in epigenetic inheritance. We show that chromatin contacts are able to trigger epimutation in Drosophila. I'm very thankful for the support of Giacomo Cavalli, @psarkies.bsky.social and to all others involved! www.cell.com/molecular-ce...
cell.com
Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila
In some cases, non-genetic information can be inherited across generations. Fitz-James et al. investigate the mechanism by which such epigenetic information becomes heritable in fruit flies. They show that physical contact between regions of DNA within the cell is able to trigger the histone modification H3K27me3 to become heritable.
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European Drosophila Society @fly-eds.bsky.social · 10/12/2024
The European Drosophila Society is delighted to join Bluesky! Follow us for the latest European fly news. #EDRC2025 #Drosophila #Drosofeed
European Drosophila Society logo: a stylised fly on blue background with yellow stars created by MC Diaz de la Loza.
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Megan McDonald @mcdonaldmeganc.bsky.social · 07/12/2024
HI old friends! Finally took the leap here to say I have several open positions going in my lab at the moment (and more to come). 1) PhD studentship in collaboration with the Royal Horticultural Society (genomics) 2) Biochemistry Postdoc to understand how Starships move Check out the links below!
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Rebecca Berrens @rberrens.bsky.social · 06/12/2024
Register now to join me at The Festival of Genomics & Biodata. My talk details here: festivalofgenomics.com/london/en/pa.... Curious? Let me know what questions I should cover in my session. Registration is free for most of the audience: hubs.la/Q02TptWZ0 #FOG2025 #TESky #transcription #nanopore
hubs.la
The Festival of Genomics & Biodata London
Join us on Wednesday 29th January & Thursday 30th January 2025 in London for 300+ inspirational speakers, the latest research and clinical breakthroughs, cutting-edge technology and incredible network...
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Fitz-James Lab @fitz-james-lab.bsky.social · 02/12/2024
We are advertising for a project looking at epigenetic inheritance in Drosophila at the Department of Biology, University of Oxford @oxfordbiology.bsky.social Please get in touch if you are interested! Only 1 month left to be considered for funding. www.findaphd.com/phds/project...
findaphd.com
How is epigenetic information inherited across generations in insects? at University of Oxford on FindAPhD.com
PhD Project - How is epigenetic information inherited across generations in insects? at University of Oxford, listed on FindAPhD.com
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Fitz-James Lab @fitz-james-lab.bsky.social · 30/11/2024
@hansonmark.bsky.social would love to be added to the insect genetics and molecular biology starter pack please!
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Fitz-James Lab @fitz-james-lab.bsky.social · 29/11/2024
Very pleased to have had a chance to present our work on epigenetic inheritance at the wonderful LabUM EpiGenMed conference at @umontpellier.bsky.social today! It was a great 3 days of talks in the sunny South of France.
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