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François Deloche

@fdeloche.bsky.social
170 followers 173 following 40 posts

Hearing science - peripheral auditory system, cochlear models, computational neuroscience. Postdoc researcher at Macquarie University (Sydney). Alumni of: Purdue, Ghent University. From Paris

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Reposted by François Deloche
Mark R. Saddler @msaddler.bsky.social · 07/10/2026
Pleased to share my new preprint with @joshhmcdermott.bsky.social and Torsten Dau: www.biorxiv.org/content/10.6... ! It shows that many of the characteristic limits of human hearing emerge from perceptual representations optimized for everyday hearing behavior. [1/6]
biorxiv.org
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Quanta Magazine @quantamagazine.org · 23/07/2026
Every four years, the math world’s preeminent awards are given to the finest minds of a generation. The young Fields and Abacus Medal winners — all under 40 on the first day of the year — have reshaped mathematics and theoretical computer science. Here are the #ICM2026 winners:
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Stephen Turner @stephenturner.us · 24/06/2026
How to give a bad talk www.nature.com/articles/s41...
How to give a bad talk https://www.nature.com/articles/s41568-026-00954-8
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Claus Wilke @clauswilke.com · 25/06/2026
People always say "tell a story" but then don't explain how to do so! How is that helping? If we knew how to tell a story we wouldn't need the advice in the first place. 1/
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Tim Kietzmann @timkietzmann.bsky.social · 26/05/2026
Our NeuroAI study made it onto the cover of Nature Machine Intelligence ❤️. In it, we demonstrate that a developmentally-inspired visual diet can drastically improve the robustness of ANN-based vision systems. www.nature.com/articles/s42... open access, open code, open weights, open science.
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Michelle Dawson @autismcrisis.bsky.social · 26/05/2026
"The starting point that the typical brain is optimal shapes both research theory (e.g., neurodevelopmental theory) and practice... We argue that this premise is false--in many ways, the brain is 'suboptimal', and importantly so" www.cell.com/trends/cogni... autism-relevant, free
cell.com
Embracing the suboptimal organization of the human brain
Human brain architecture is guiding brain-inspired artificial intelligence (AI) and has been treated as an optimal template, whose deviations could mark different psychiatric and neurological conditio...
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The Transmitter @thetransmitter.bsky.social · 01/04/2026
Catherine Carr explains her discovery that geckos retain a vibration-sensing pathway previously thought to be lost when animals moved onto land. By @helenak.bsky.social #neuroskyence" www.thetransmitter.org/neuros-ark/n...
thetransmitter.org
Neuro’s ark: Sounding out the evolution of hearing with geckos
Catherine Carr explains her discovery that geckos retain a vibration-sensing pathway previously thought to be lost when animals moved onto land.
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Jennifer Groh @jmgrohneuro.bsky.social · 27/03/2026
Science peeps! Excited to share first of two preprints just uploaded. This one concerns a person who hears sounds when she moves her eyes! We could actually record these sounds and verify they were connected to eye movements 1/ www.biorxiv.org/content/10.6...
biorxiv.org
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Renato Duarte @rcfduarte.bsky.social · 11/03/2026
I tracked every keyword in 22 years of Cosyne abstracts to map how computational neuroscience evolved — from Bayesian brains to neural manifolds to LLMs — and where it's heading next.
open.substack.com
22 years of Brain Science: what CoSyNe tells us about the evolution of Neuroscience
Tracking the intellectual DNA of Computational and Systems Neuroscience through its flagship meeting
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Jay 🦋 @jay.bsky.team · 09/03/2026
Some personal news: I’m transitioning from CEO to a new role as Bluesky’s Chief Innovation Officer! I’m excited to welcome @toni.bsky.team as our interim CEO. More here: bsky.social/about/blog/0...
bsky.social
A New Chapter for Bluesky - Bluesky
After several intense and incredible years building Bluesky from the ground up, I've decided to step back as CEO and transition to a new role as Bluesky's Chief Innovation Officer.
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Joshua Weitz @joshuasweitz.bsky.social · 07/03/2026
The data is in: the NIH goalposts have shifted. What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards. Another manifestation of how HHS policies have led to fewer awards and less science.
Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success.

Data source: https://report.nih.gov/nihdatabook/report/302
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Uri Manor @manorlaboratory.bsky.social · 19/02/2026
A fun (AI-enhanced) image of 12187 ABR waveforms. We used these data from our own lab and several others to train ABRA (PMID: 38948763) and are still using it to train next-gen machine learning models for cochlear studies. Stay tuned (no pun intended) for more!
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Konrad Kording @kordinglab.bsky.social · 26/02/2026
This paper on how the brain may do gradient descent is very cool: www.nature.com/articles/s41...
nature.com
Vectorized instructive signals in cortical dendrites - Nature
Mice learning a neurofeedback brain–computer interface task show neuron-specific teaching signals in cortical dendrites, consistent with a vectorized solution for credit assignment in the brain.
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Jennifer Groh @jmgrohneuro.bsky.social · 10/02/2026
Hey #ARO2026, today we have a poster on an interesting participant who hears sounds when her eyes move! Board #134 1/
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Theo Sanderson @theo.io · 08/02/2026
I made a map of 3.4 million Bluesky users - see if you can find yourself! bluesky-map.theo.io I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail
bluesky-map.theo.io
Bluesky Map
Interactive map of 3.4 million Bluesky users, visualised by their follower pattern.
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Neuroskeptic @neuroskeptic.bsky.social · 25/01/2026
"How much of the brain's learned algorithms depend on the fact it is a brain?" arxiv.org/abs/2601.02063 The brain is a neural network, but also a biological organ (unlike artificial neural networks). How much does this matter to cognition?
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Mayank Mehta @mayankmehta.bsky.social · 31/12/2025
Bye bye 2025, a divisive year, with many divisors: 3, 5, 9, 15, 25, 27, 45, 75, 81, 135, 225, 405, 675. Happy 2026 = 2*1013 Just two primes Cheers!
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CNRS @cnrs.fr · 17/12/2025
Du format de compression d’images JPEG 2000 aux fondements mathématiques de l’IA, Stéphane Mallat a façonné des outils devenus incontournables. Pour ses travaux exceptionnels, il reçoit la médaille d'or 2025 du CNRS. #TalentsCNRS 🏅 Son portrait vidéo 👉 youtu.be/m3zNvnGSjjk
youtu.be
Stéphane Mallat, bâtisseur de ponts mathématiques et informatiques | Talents CNRS
YouTube video by CNRS
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François Deloche @fdeloche.bsky.social · 31/10/2025
Each year amazed by the incredible carving work of Purdue Audiology student Isabella Huddleston 🤩🤩 via x.com/HeinzLab_Pur... #Halloween 🎃👻
pumpkin carving representing the inner ear. left: inner ear, center: transverse section of the cochlear duct, right: spiral canal, modiolus and sprial ganglion
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Sam Gershman @gershbrain.bsky.social · 14/10/2025
Really interesting work by Bakhurin and colleagues challenging the reward prediction error hypothesis of dopamine: www.nature.com/articles/s41... I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
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Zach Rosenthal @zachrosenthal.bsky.social · 24/09/2025
Super proud of this collaboration with rockstar Ryan Raut - born out of playing in the sandbox in our last year of grad school! Multi-scale brain activity can be predicted from a simple measure of arousal like pupil diameter. Out with linear causality, in with dynamic systems to explain neurobiology
nature.com
Arousal as a universal embedding for spatiotemporal brain dynamics - Nature
Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.
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Ben Hayden @benhayden.bsky.social · 22/09/2025
New manuscript from the lab! "Mirror manifolds: partially overlapping neural subspaces for speaking and listening" Led by superstar grad student Anilu Chavez (not on Bluesky)! www.biorxiv.org/content/10.1...
biorxiv.org
Mirror manifolds: partially overlapping neural subspaces for speaking and listening
Participants in conversations need to associate words their speakers but also retain those words general meanings. For example, someone talking about their hand is not referring to the other speakers ...
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François Deloche @fdeloche.bsky.social · 11/09/2025
I had the chance to have Stephane Mallat as a teacher. His course connected important ideas in statistical signal processing/machine learning with mathematical concepts. It was very inspiring I know him as a great mentor. His book 'a wavelet tour on signal processing' is a classic IMO :)
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The Rockefeller University @rockefeller.edu · 18/08/2025
We are deeply saddened to share that our friend and colleague Jim Hudspeth passed away on Saturday. We will remember and continue to be inspired by Jim’s integrity, his humility, and his unwavering commitment to discovery.
rockefeller.edu
A. James Hudspeth, neuroscientist who unlocked secrets of hearing, has died - News
A. James Hudspeth, a Rockefeller neuroscientist who discovered how sound waves are converted into electrical signals in the ear's cochlea, died Saturday at his home in Manhattan. A pioneering scientist and dedicated mentor, he was the university's F.M. ...
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Uri Manor @manorlaboratory.bsky.social · 18/08/2025
Jim Hudspeth has died 💔 I am so sad. He was probably my favorite hearing researcher of all time. Absolute genius and also generous - he spent hours on the phone advising me on my career even tho we barely knew each other. May his memory be a blessing. www.ted.com/talks/jim_hu...
ted.com
Jim Hudspeth: The beautiful, mysterious science of how you hear
Have you ever wondered how your ears work? In this delightful and fascinating talk, biophysicist Jim Hudspeth demonstrates the wonderfully simple yet astonishingly powerful mechanics of hair cells, th...
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Akira Miyake @amiyake.bsky.social · 08/08/2025
I love this experience-sampling study on the absolute pitch of earworms! It's a really nicely done study conducted in everyday settings. The link to this paper (open access) is provided below. It is also featured in a podcast (tinyurl.com/4ydrw5zp) by the Psychonomic Society. Congrats!
link.springer.com
Absolute pitch in involuntary musical imagery - Attention, Perception, & Psychophysics
Memory for isolated absolute pitches is extremely rare in Western, English-speaking populations. However, past research has found that people can voluntarily reproduce well-known songs in the original...
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Antonino Greco @agreco.bsky.social · 09/08/2025
🔵 Proud to share our new preprint 🔵 We compared humans and deep neural networks on sound localization 👂📍 Humans robustly localized OOD sounds even without primary interaural cues (ITD & ILD) Models localized well only in-training distribution sounds, failing on OOD regime Link & full story 🧵👇
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Flor Iacaruso @flor-iacaruso.bsky.social · 01/08/2025
1/N What are the organizational principles underlying crossmodal cortical connections? We address this in this new preprint, led by @alexegeaweiss.bsky.social & ‪@bturner-bridger.bsky.social‬ in collab w/ ‪@petrznam.bsky.social‬ @crick.ac.uk www.biorxiv.org/content/10.1...
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Meg Tirrell @megtirrell.bsky.social · 29/07/2025
A major NIH grant to study ways to restore hearing was terminated by the Trump administration bc it was awarded through a DEI initiative—to a researcher who qualified bc of his own hearing loss www.cnn.com/2025/07/29/h... @manorlaboratory.bsky.social
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Blake Richards @tyrellturing.bsky.social · 11/07/2025
1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex: www.biorxiv.org/content/10.1... I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction. But... 🧠📈 🧪
biorxiv.org
Sensory responses of visual cortical neurons are not prediction errors
Predictive coding is theorized to be a ubiquitous cortical process to explain sensory responses. It asserts that the brain continuously predicts sensory information and imposes those predictions on lo...
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François Deloche @fdeloche.bsky.social · 02/07/2025
👏
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Sheffield Hearing Group @hearingshef.bsky.social · 02/07/2025
Howdy! Today's paper spotlight comes from Chun Liang and was published in June. This paper shows that knocking out the ATP gated receptor P2X7 enhances hearing sensitivity but makes noise induced cochlea damage much worse! Adds info to those mysterious type II fibres 🔍 www.pnas.org/doi/10.1073/...
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François Lallemend @flallemend.bsky.social · 02/07/2025
Gene therapy to treat deafness now a success in young adults! www.nature.com/articles/s41...
nature.com
AAV gene therapy for autosomal recessive deafness 9: a single-arm trial - Nature Medicine
Preliminary results from an investigator-initiated clinical trial showed that an AAV-OTOF gene therapy was safe and led to hearing improvements in ten patients with congenital deafness with 6–12 month...
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Paula Kuokkanen @paulakuokkanen.bsky.social · 28/06/2025
Delighted to have our newest paper out in #Jneurosci ! We looked at how much a single cell contributes to an auditory-evoked EEG signal. Big thanks to my co-authors Ira Kraemer, Christine Köppl, Catherine Carr and Richard Kempter (all not in Bsky). Here’s how: (1/13) bsky.app/profile/sfnj...
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Dan Levenstein @dlevenstein.bsky.social · 26/06/2025
Does anyone else find it perpetually annoying that what most folks would consider neural "computation" is Marr's "algorithmic" level, while his *computational* level is really just "what's the goal of this thing anyway?" AKA function.
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François Deloche @fdeloche.bsky.social · 16/06/2025
[PAPER ALERT 🚨] Happy to share our new publication 'Active control of transverse viscoelastic damping in the tectorial membrane: A second mechanism for traveling-wave amplification? ' also presented at the Mechanics of Hearing workshop last year. authors.elsevier.com/a/1lFhQ1M5IZ...
authors.elsevier.com
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Sheffield Hearing Group @hearingshef.bsky.social · 05/06/2025
Today's #PaperSpotlight comes from Patricia M. Quinones et al, published in April this year. The study mainly used optical coherence tomography (OCT), and interestingly showed that silencing inner hair cells led to larger sound-induced vibrations in the cochlea! 🔗: www.jneurosci.org/content/45/1...
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University of Rochester BME (Biomedical Engineering) @uofrbme.bsky.social · 02/06/2025
👏 Dr. Laurel Carney has been named the 2025 David T. Blackstock Mentorship Award from the Acoustical Society of America (@asa-news.bsky.social‬)! Honored for her outstanding #mentorship in #acoustics & #hearing research. 🔗 Read more: tinyurl.com/uofrbme-carney-blackstock #facultyawards #Meliora!
hajim.rochester.edu
Laurel Carney Wins ASA Blackstock Mentorship Award
Related Links...
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Léo Varnet @leovarnet.bsky.social · 27/05/2025
Yesterday I defended my 'Habilitation à diriger des Recherches'! Thanks to those who attended! And thank you to a wonderful jury: J. Gervain, A. Calcus, I. Chitoran, J.J. Aucouturier, E. Gaudrain, C. Lorenzi.
Myself, in front of the title slide "une étude microscopique des mécanismes auditifs de la perception du langage oral".
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Mickaël Launay @mickaellaunay.bsky.social · 25/05/2025
Bonjour, nous sommes le
Ma main tient un papier carré sur lequel est ecrit 2025 perpendiculairement à un miroir. Avec la symetrie, on peut lire 25 05 2025.
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Jean-Rémi King @jeanremiking.bsky.social · 15/05/2025
Crucially, these language representations evolve with age: while fast phonetic features are already present in the superior temporal gyrus of the youngest individuals, slower word-level representations only emerge in the associative cortices of older individuals.
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Phie Jacobs @phiejacobs.bsky.social · 07/05/2025
The Deaf Scientists Pipeline in Rochester, NY offers support for students and researchers from high school to postdoctoral levels. Now, due to NIH funding cuts, this one-of-a-kind initiative has been dismantled. My recent story for @science.org
science.org
Crucial training pipeline for Deaf scientists dismantled by NIH funding cuts
The one-of-a-kind initiative offered support from high school to postdoctoral levels
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Michelle Dawson @autismcrisis.bsky.social · 08/05/2025
Karl Friston explains autistic meltdowns? psycnet.apa.org/record/2026-... "chronic hypervigilance, acute hyperreactivity, and ultimately meltdowns in autism reflect a reduction in deep inference within the interoceptive predictive coding hierarchy"?
psycnet.apa.org
APA PsycNet
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Nicole Rust @nicolecrust.bsky.social · 25/04/2025
A putative neural correlate of mood! One big (scandalous?) idea, simple analyses, and the STRONGEST brain/behavior correlation I've EVER seen (which is shocking, given that it's mood). Work with: You-Ping Yang, @catrinahacker.bsky.social and Veit Stuphorn. www.biorxiv.org/content/10.1...
biorxiv.org
The representation of mood in primate anterior insular cortex
Understanding how the brain reflects and shapes mood requires resolving the disconnect between behavioral measures of mood that can only be made in humans (typically based on subjective reports of hap...
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BWJones @bwjones.bsky.social · 23/04/2025
If your perception is that all interactions are transactional and that there is no such thing as sincerity of curiosity, or a desire to discover, then you will never value science. No matter how many economic arguments there are for funding it. Because you don’t understand the fundamental premise.
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Patrick Mineault @patrickmineault.bsky.social · 18/04/2025
I asked o3 for help with LaTeX quote boxes. This is the example quote it used. The machines are on to us.
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Lauer Lab @lauerlab.bsky.social · 10/04/2025
This federal research funding situation is stressful for all scientists in the US, but I’m especially disheartened about what is happening to the training and career development grants. We need to cultivate the best and brightest, no drive them away! 👩‍🔬🧑‍🔬😡
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Sam Gershman @gershbrain.bsky.social · 10/04/2025
I'm fascinated by how machine learning is increasingly looking like traditional neuroscience (replacing prediction with explanation) while neuroscience is increasingly looking like traditional machine learning (replacing explanation with prediction).
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Hari Bharadwaj @haribharadwaj.bsky.social · 22/03/2025
Taking a moment to celebrate new science with a paper alert 🚨 🎉 Congratulations to @samhauser.bsky.social, and co-authors Alexandra Hustedt-Mai and Anna Wichlinski on the latest publication from our lab in The Journal of the Acoustical Society of America! doi.org/10.1121/10.0... (1/5)
doi.org
The relationship between distortion product otoacoustic emissions and audiometric thresholds in the extended high-frequency range
Distortion product otoacoustic emissions (DPOAEs) and behavioral audiometry are routinely used for hearing screening and assessment. These measures provide rela
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