Using a combined approach of monkey electrophysiology, artificial neural networks and human psychophysics, Xue et al. show that neuronal interference from irrelevant information underlies behavioral e...

This study leverages cell type-specific optogenetics in the monkey cerebral cortex to elucidate the unique functional contributions of excitatory and inhibitory neurons in visual form processing. The ...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Finding your way home in the dark can be challenging, but pigeons have developed surprising navigational strategies to sense magnetic fields to make it home safe.

uses statistical and theoretical approaches to study the neural basis of flexible behavior

Functional synapse clusters (FSCs) are synapses with correlated presynaptic activity that are colocalized on the same neuronal dendritic branch. FSCs have been observed after learning in cortical and ...

In macaques, old memories, relative to new ones, are supported by more stable and interconnected cell assemblies. New-biased and old-biased assemblies reactivate during overnight sleep and can sometim...

Abstract. Decades of research have established the hippocampus as central to episodic memory, but growing evidence suggests that it also contributes to str

Shared trial-to-trial variability across sensory neurons is reliably reduced when perceptual performance improves, yet this variability is low dime...

Busch et al. use nonlinear neural manifolds to help humans gain rapid control over a noninvasive brain–computer interface, allowing them to learn how to play a video game with real-time fMRI neurofeed...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Science chats with a researcher whose team is using “timescapes” to understand how nonhumans experience the world

To solve diverse real-world tasks, the brain must flexibly switch between task rules and adjust computations. Recent advances in analyzing neural data and modeling neural networks have revealed their ...

Summary: The call to arms for alternatives to model organisms of disease will fail without ongoing integration with – and validation against – complex animal models and support from the animal modelli...

In the hippocampus, complex processing of sensory stimuli occurs even in the unconscious state.

This Earth Day three environmental experts share stories about times when environmental action succeeded in saving the planet—and explain why this can be done again

Mengting Fang, Psychology “Pause, Then Power: How the Brain Decides When to Work Hard” Natural Sciences Presentations | March 27, 2026 Penn Grad Talks (formerly known as Grad Ben Talks) features TE...

Mental imagery allows us to remember previous experiences and imagine new ones. Animal studies have yielded rich insight into mechanisms for visual perception, but the neural mechanisms for visual imagery remain poorly understood. We determined that ...

Nature - A brain–machine interface is used in monkeys to investigate the biophysical underpinnings of cortical high gamma-band activity, a signal that is often studied in the context of many...