Viruses are ubiquitous mobile genetic elements that are obligate symbionts of cellular life forms and replicate exclusively within host cells. The ...

Cyclic transcription is a hallmark of the cell cycle. While transcriptional waves in eukaryotes are driven by oscillations in cyclin-dependent kinase (CDK) activity, many archaea have an ordered cell ...

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Abstract. In prokaryotes, bidirectional promoters are pseudo-symmetrical DNA sequences that stimulate divergent transcription. Ubiquitous, and far more lik

DNA topoisomerases are essential enzymes found in all cells, where they regulate DNA supercoiling. Reverse gyrase (RG) is a unique type of topoisomerase that introduces positive supercoils into DNA an...

Bona fide gene clusters for archaella are widespread across a bacterial phylum and encode functional motility machinery.

Proteins SegA and SegB are important for chromosome segregation and organization in archaea of the order Sulfolobales, but mechanisms are unclear. Here, Kabli et al. uncover patterns and mechanisms th...

Nature Communications - The cell cycle of the archaeon Saccharolobus islandicus displays similarities to that of eukaryotic cells. Here, the authors use transcriptomic analysis of synchronized...

Histones are fundamental chromatin-organizing proteins in eukaryotes and archaea, where they assemble into (hyper)nucleosomes that wrap DNA. Recent studies have expanded the known repertoire of histon...

In an iron-sulfide chemical garden experiment that mimics the kind of hydrothermal vents that might have occurred in the early Archaean, mackinawite and greigite are precipitated and abiotic H2 is pro...

Research Associate (Fixed Term) in the Department of Genetics at the University of Cambridge.

PhD Project - Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews, listed on FindAPhD.com

PhD Project - Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea at University of York, listed on FindAPhD.com