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Eduardo Marbán, MD, PhD

@eduardomarban.bsky.social
188 followers 239 following 34 posts

Executive Director, @SmidtHeart.bsky.social at Cedars-Sinai Medical Center Views are my own.

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Reposted by Eduardo Marbán, MD, PhD
JCI insight @insight.jci.org · 14/09/2026
Suggesting a novel therapy for systemic sclerosis: doi.org/10.1172/jci.... @eduardomarban.bsky.social & team report that an orally delivered noncoding RNA (TY1) reduces inflammation and organ fibrosis in models of systemic sclerosis through inhibition of the cGAS/STING axis. @the-asci.org
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 08/09/2026
Excited to share our latest paper in @insight.jci.org, with Michael Jones, Salwa Soussi & @ahmedgibrahim.bsky.social: #TY1, an #RNA #exomer drug, reverses the key disease manifestations of #scleroderma in two mouse models and in human #SSc cells. 📃https://insight.jci.org/articles/view/197716
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Reposted by Eduardo Marbán, MD, PhD
Ying Ge @yingge2121.bsky.social · 09/11/2025
#AHA25 also congratulations to @eduardomarban.bsky.social for receiving the George Brown lectureship and Jiang Chang for the Thomas Smith lectureship! Well-deserved ❤️🎉👍🙌
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 23/09/2025
Delighted to welcome these three new stars to our faculty: Stephen Nageotte and Mark Sklansky to our congenital heart program, and Eli Friedman to lead #SportsCardiology!
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 29/07/2025
For the 12th year in a row, @smidtheart.bsky.social has been ranked #1 in California for Cardiology, Heart, and Vascular Surgery by @usnews.com! www.cedars-sinai.org/newsroom/ced...
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 04/06/2025
Fascinating @smidtheart.bsky.social research seminar by Farah Sheikh of @ucsandiego.bsky.social on #ARVC— #BenchToBedside journey towards AAV gene therapy with PKP2, now in clinical trials!
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 19/05/2025
Our lab hosts a few select UCLA #undergraduates as #interns. One of our stellar interns, working with #postdoc Junlang Li, just presented her work at the Undergraduate Research & Creativity Showcase— #EVs from #iPSCs— check it out! youtu.be/ElnJW6-UrqQ
youtu.be
Medical Research: Prerecorded - Panel 9 - Presentation 4
YouTube video by UCLA Undergraduate Research Centers
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 07/05/2025
Congrats Sumeet! www.beckershospitalreview.com/hospital-exe...
beckershospitalreview.com
Cedars-Sinai appoints chief AI health research officer - Becker's Hospital Review | Healthcare News & Analysis
Los Angeles-based Cedars-Sinai has promoted Sumeet Chugh, MD, to serve as vice dean and chief artificial intelligence health research officer.  In this newly created role, Dr. Chugh will lead efforts ...
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Reposted by Eduardo Marbán, MD, PhD
The American Society for Clinical Investigation @the-asci.org · 02/05/2025
Healing the heart! @eduardomarban.bsky.social & team discover the long non-coding RNA BCYRN1 contained in extracellular vesicles from cardiosphere-derived cells modulates Tregs and reduces damage in a mouse heart-attack model: buff.ly/n1q0Bac
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Reposted by Eduardo Marbán, MD, PhD
Journal of Clinical Investigation @jci.org · 02/05/2025
Healing the heart! @eduardomarban.bsky.social & team discover the long non-coding RNA BCYRN1 contained in extracellular vesicles from cardiosphere-derived cells modulates Tregs and reduces damage in a mouse heart-attack model: buff.ly/n1q0Bac
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 01/05/2025
Pleased to share our paper: #EVs released from #heart #postMI travel to #brain and cause #neuroinflammation, underlying #depression. Work of Ke Liao, PhD ahajournals.org/doi/epub/10.11…
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Reposted by Eduardo Marbán, MD, PhD
Russell Rogers, Ph.D. @russellrogers.bsky.social · 22/04/2025
Wonderful Research In Progress update by NIH T32 Fellow, Jonah Zarrow, on developing novel #ncRNA drugs for #Duchenne muscular dystrophy. Important work for #DMD! @eduardomarban.bsky.social @smidtheart.bsky.social @mda.org
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Reposted by Eduardo Marbán, MD, PhD
Eugenio Cingolani, MD @eugeniocingolani.bsky.social · 09/04/2025
Great #Breakout #Session at Cedars Sinai Faculty Retreat #NewTherapies from #Concept to #Clinic Fantastic panel ➡️ Dr. Eduardo Marban @eduardomarban.bsky.social describing his pathway to #clinic #CDCs followed by Dr. Anand Karumanchi going over his experiences towards #translation #regulatorypathways
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 08/04/2025
Brilliant @smidtheart.bsky.social research seminar by Rajan Sah MD PhD of Washington University on SWELL channels and their role in #platelet #thrombosis. Big implications for therapeutics of #MI and #stroke. #CardioSky
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 08/04/2025
Provocative @smidtheart.bsky.social #cardiology grand rounds by Rita Redberg who highlights the low bar set for @fda.gov approval of medical devices. Hard clinical endpoints in adequately powered trials sorely lacking. No wonder investors prefer devices over drugs or novel biological therapies!
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 06/04/2025
Inspiring start to Cedars Sinai’s academic retreat by Shlomo Melmed, MD, who emphasizes how our unique structure enables progress towards science-based clinical innovation.
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 03/04/2025
New discoveries abound in @ahmedgibrahim.bsky.social as evidenced today by #labmeeting on #EVs and #ncRNAs from genetically engineered #fibroblasts that pulled a Jekyll and Hyde, becoming salutary post- #MI. Great work of Hiroaki Komuro! #CardioSky
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 28/03/2025
Let's get #ACC25 started! ⬇️Check out the agenda and don't miss hearing from @smidtheart.bsky.social! Follow us all weekend for highlights! @accintouch.bsky.social
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 27/03/2025
Recent paper published in @jclinical-invest.bsky.social from @eduardomarban.bsky.social & Ke Liao finds a #ncRNA that enhances #Treg cells that could potentially repair heart muscle damage after a #HeartAttack & be applied to a variety of inflammatory disorders. www.cedars-sinai.org/newsroom/pre...
cedars-sinai.org
Preclinical Study: After Heart Attack, a Boost in Anti-Inflammatory Cells Promoted Healing
A scientific technique that rapidly increases the body’s production of anti-inflammatory cells promoted healing from heart attacks in mice, according to a new study by investigators from the Smidt Hea...
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 25/03/2025
Check out the in-press preview of our @jclinicalinvest paper on regulatory #Tcells — we discovered a #ncRNA that can enhance #Treg dynamics fast enough to improve #MI healing in vivo. New hope for refractory inflammatory and immune conditions? 🔗 www.jci.org/articles/vie...
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 21/03/2025
We’re ready for day 2 of the #HFpEFSummit listening in on sessions about exercise intolerance and the new and late breaking clinical trials! Exciting day ahead!
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 21/03/2025
@russellrogers.bsky.social discussed experiments w/Lefer Lab taking advantage of the mechanistic differences between #GLP1RA & #ncRNA #TY1 as therapeutics for #HFpEF. Compelling evidence for synergistic benefits in two rodent models! Potential for less skeletal muscle loss? @smidtheart.bsky.social
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 20/03/2025
The incomparable @mkittlesonmd.bsky.social teaches us that #HFpEF is a diagnosis of exclusion— rule out AS, HCM, pericardial constriction and, above all, #amyloidosis.
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Reposted by Eduardo Marbán, MD, PhD
Russell Rogers, Ph.D. @russellrogers.bsky.social · 20/03/2025
Pleased to share out latest work on cell therapy for #Duchenne. We show #deramiocel therapy initiated early protects against disease-related decline in muscle function. @eduardomarban.bsky.social @smidtheart.bsky.social @stemcellreports.bsky.social @mda.org
cell.com
Long-term preservation of muscle function and structure by repeated administration of cardiosphere-derived cells in mdx mice
Duchenne muscular dystrophy (DMD) is a progressive disease associated with functional decline. Chronic administration of cardiosphere-derived cell therapy prevents disease-related functional decline f...
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 20/03/2025
Single nuclei #RNAseq of human #HFpEF heart biopsies by Virginia Hahn of @hopkinsheart.bsky.social reveals interesting #macrophage specific changes. Lots of provocative findings!
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 20/03/2025
Great opening lecture by #HFpEF pioneer @dakheartguy.bsky.social on #sarcomere abnormalities— huge differences in #calcium activated force in #myocytes from obese vs morbidly obese patients. Clinical correlation less evident… @smidtheart.bsky.social #CardioSky
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 19/03/2025
The final agenda is up! We can't wait to see you tomorrow. Follow us Thursday and Friday for meeting highlights! #HFpEF
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 28/02/2025
We are less than 3 weeks away from the start of the #HFpEF Conference! There's still a few spots left, grab your seat now. Registration🔗 hfpefsummit.org
hfpefsummit.org
Home | HFpEF Summit
Join the HFpEF Summit, March 19–21, 2025, at The Maybourne Beverly Hills. Connect with global leaders in HFpEF research.
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 28/02/2025
On #RareDiseaseDay, we honor the families who are fighting for a cure. #DuchenneMD, a disease that weakens muscles & affects the heart. Research led by @eduardomarban.bsky.social offers hope through #CellTherapy slowing #HF. This breakthrough may extend lives & change futures. tiny.cc/8hob001
cedars-sinai.org
Potential Treatment for Heart Disease Caused by Duchenne MD
Catherine Jayasuriya thought it was strange her then-6-year-old son, Dusty Brandom, seemed to fall down more often than other children and couldn’t keep up with his siblings. That year, 1998, Jayasuri...
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Reposted by Eduardo Marbán, MD, PhD
Barbra Streisand Women's Heart Center @womensheart.bsky.social · 28/02/2025
Echoing this! 💙 A big THANK YOU to our fellows for your hard work and dedication—you make a difference every day! #ThankAFellow #HeartHeroes
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 27/02/2025
👋 Say hi to our friends at @womensheart.bsky.social! Be sure to follow to keep up with the latest news from our Barbra Streisand Women's Heart Center. 🫶 #CardioSky
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 25/02/2025
Inspiring kickoff to @fda.gov Cell Therapy workshop with keynote lecture by Sally Temple— PSC-derived neural cells are coming into their own! FDA CBER has been highly supportive of this transformative field.
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 25/02/2025
@smidtheart.bsky.social discoveries translated to the clinic….. Potential Treatment for Heart Disease Caused by Duchenne Muscular Dystrophy www.cedars-sinai.org/newsroom/duc...
cedars-sinai.org
Potential Treatment for Heart Disease Caused by Duchenne MD
Catherine Jayasuriya thought it was strange her then-6-year-old son, Dusty Brandom, seemed to fall down more often than other children and couldn’t keep up with his siblings. That year, 1998, Jayasuri...
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 21/02/2025
Terrific editorial by Noel Bairey Merz, Holly Andersen and @drmarthagulati.bsky.social lamenting the dire consequences of federal funding cuts for women's heart health-- will 4 decades of progress be undone? @womensheart.bsky.social @smidtheart.bsky.social
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 20/02/2025
In an effort to pretend life is normal and we can just talk science, our #journalclub today featured Liz on the lasting epigenomic traces of #obesity; Diana on ML-directed #protein #evolution; and James critiqued #iPSC #cardiomyocyte sheets. A welcome distraction from the prevailing woes about NIH.
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 20/02/2025
On Feb 25, @fda.gov is proceeding with its scheduled workshop on #celltherapy. The agenda starts with an address by CBER Director Peter Marks, WarpSpeed hero, and is packed thereafter. Tune in for my session at 230PM EST. 🔗 www.fda.gov/news-events/...
fda.gov
Cell Therapies and Tissue-Based Products: A Public Workshop on Generat
CBER, OTP is hosting a virtual scientific public workshop on February 25, 2025, titled “Cell Therapies and Tissue-based Products: A Public Workshop on Generating Scientific Evidence to Facilitate Deve...
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 19/02/2025
We're proud to share with the community the @smidtheart.bsky.social Institute's 2025 Quarterly Report. 🔗 www.cedars-sinai.edu/health-scien...
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 17/02/2025
Great plenary talk by Jennifer Van Eyk at Cardiac Muscle Society meeting on #proteomics of the 🫀— inspiring journey of discovery from 2d gels of tissue to single-cardiomyocyte protein profiling!
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 13/02/2025
Exciting new findings on #SAnode dysfunction in #HFpEF by Thassio Mesquita in our #labmeeting today. Chronotropic incompetence is due to intrinsic #pacemaker abnormalities! #CardioSky
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 12/02/2025
We're counting down to the HFpEF Summit! 🗓️March 19-21 🏨Beverly Hills, CA Looking forward to hearing from a great line up of internationally recognized leaders in the clinical, biological, and translational study of #HFpEF. See you there! 🔗 hfpefsummit.org
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 08/02/2025
We wear red to raise awareness about heart disease in women. Let’s stand together to spread the message of heart health, prevention, and action. ❤️ #WearRedDay #GoRedForWomen
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Reposted by Eduardo Marbán, MD, PhD
Jeanna Huynh @jeannahuynh.bsky.social · 07/02/2025
Our labs got our red on! @russellrogers.bsky.social @ahmedgibrahim.bsky.social @eduardomarban.bsky.social #WearRedDay #GoRedForWomen
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 07/02/2025
Don’t forget it’s Wear Red Day! Join us in wearing red today to raise awareness for women's heart health! Together, we can spread knowledge, inspire action, and empower women to take charge of their heart health. Share with us your red outfit of the day! #WearRedDay #GoRedForWomen
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 04/02/2025
A great pleasure to host my former #postdoc @stevenpjones.bsky.social of the @cardiometabosci.bsky.social @uoflenvirome.bsky.social as Visiting Professor in our @smidtheart.bsky.social #Frontiers seminar series. The intersection of #metabolism and #inflammation is vital!
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 01/02/2025
February is American Heart Month! Let's unite and wear red on Friday Feb 7 to support women's heart health. Let's spread awareness, encourage healthy habits, and take care of our hearts! ❤️ #HeartHealth #WearRed #GoRedForWomen #cardiosky
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 31/01/2025
Day 2 of Controversies is on the way with discussions on #EP #Imaging #CAD #AI #HeartFailure #INOCA See you soon!
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 31/01/2025
Stimulating discussion of best therapy for #bicuspid #aortic #stenosis by, among others, Aakriti Gupta and Michael Bowdish. Paradoxical realization that bioprosthetic valves may be worse than mechanical ones in young people…. Let alone #TAVR vs #SAVR.
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 31/01/2025
Provocative summary of #AI in #medicine by Sumeet Chugh. #CardioSky @smidtheart.bsky.social
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Reposted by Eduardo Marbán, MD, PhD
Smidt Heart Institute @smidtheart.bsky.social · 30/01/2025
Controversies afternoon keynote lecture delivered by @eduardomarban.bsky.social discussing the development of a new #ncRNA drug to treat #Scleroderma/#SystemicSclerosis
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Eduardo Marbán, MD, PhD @eduardomarban.bsky.social · 30/01/2025
Great talk on #Lpa by @drmarthagulati.bsky.social in @smidtheart.bsky.social outstanding #Controversies meeting!
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