Nature - Spatial proteomics is helping biologists to uncover how cells work by mapping where proteins operate.

Algorithms for studying knots and other topological objects could have a quantum advantage.

Spatial proteomics is helping biologists to uncover how cells work by mapping where proteins operate.

Multiple gene therapy approaches for Duchenne muscular dystrophy (DMD) have been under development for more than 35 years. AAV-mediated delivery of miniaturized dystrophin genes have shown some encouraging results and led to initial FDA approval of one drug. Here we review challenges and future prospects for AAV methods for DMD.

Sequencing of 7,000-year-old human genomes from when the Sahara Desert was green suggest that pastoralism spread through cultural exchange, not large-scale migration.