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Dirk Metzler

@dirkmetzler.bsky.social
231 followers 220 following 17 posts

stochastic modelling in biology, evolutionary bioinformatics, theoretical population genetics, evolutionary (epi)genomics and transcriptomics

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Reposted by Dirk Metzler
SPP 2349 Gevol @gevol.bsky.social · 01/10/2026
🌞 Our GEvol SPP had a fantastic, sunny annual meeting in beautiful Halle (Saale) over the last three days. It was particularly lovely to welcome the many new students joining us for our second GEvol phase. We’re looking forward to having a great time with you all. 🐞
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Katie Martin @katie0martin.ft.com · 25/09/2026
I have blamed The agents That hacked Your website And which You probably Reasonably thought I controlled Forgive me I am rich And unaccustomed To taking responsibility
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Mario Stanke @masta.bsky.social · 10/09/2026
With his program, Vipsania, Richard Krieg has shown, that it is possible to do unsupervised deep gene finding with masked language modeling The trick: use an HMM in the middle of the deep-learning architecture that knows the grammar of gene structures. preprint: www.biorxiv.org/content/10.6...
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Janoschki @janoschki.bsky.social · 10/08/2026
Po, Rhein, Loire 2026.
Stahlbrücke über ein fast vollständig ausgetrocknetes Flussbett des Po – nur ein schmaler Wasserlauf schlängelt sich durch die weite, sandig-kiesige Fläche mit vereinzelten grünen Büschen, im Hintergrund landwirtschaftliche Felder und Hügel unter blauem Himmel mit Wolken.Flussschleife mit der Burg Pfalzgrafenstein auf einer sandigen Insel inmitten des Rheins, umgeben von deutlich freiliegenden Kies- und Sandbänken, im Hintergrund eine bewaldete und mit Weinbergen bewachsene Uferlandschaft sowie eine Ortschaft entlang des Ufers.Weites, größtenteils trockengefallenes Flussbett der Loire mit ausgedehnten hellen Sandbänken, durch die sich nur noch schmale, dunkle Wasserrinnen ziehen. Eine lange Hängebrücke überspannt das Flussbett, am rechten Bildrand eine Ortschaft mit Wohnhäusern, im Hintergrund grüne Uferwälder.
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Dirk Metzler @dirkmetzler.bsky.social · 30/07/2026
Congratulations to Priscilla and many thanks for the great collaboration!
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Amrei Bahr @amreibahr.bsky.social · 05/07/2026
Uuund die 200.000-Marke ist locker geknackt! 🤩 Großartig! Da geht noch mehr, oder? 💪 #Informationsfreiheitsgesetz @fragdenstaat.de
weact.campact.de
SPD, stoppt den Frontalangriff auf die Informationsfreiheit!
Wir alle haben das Recht auf staatliche Informationen. Seit 2006 müssen Behörden auf Antrag nach dem Informationsfreiheitsgesetz (IFG) Dokumente herausgeben – seien es Verträge, interne Weisungen oder...
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Wolf Lab @jochenwolflab.bsky.social · 17/06/2026
Looking for a postdoc opportunity in evolutionary genetics? Join the Wolf Lab at LMU Munich. job-portal.lmu.de/jobposting/7...
job-portal.lmu.de
Postdoctoral Researcher in Evolutionary Genetics (m/f/x)
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Itai Yanai @itaiyanai.bsky.social · 24/06/2026
🔥 Published today, and just in time for summer conferences, here are your guidelines for presenting badly www.nature.com/articles/s41... rdcu.be/fqa92
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Wolfgang Huber @wkhuber.bsky.social · 10/06/2026
One of the good things about the AI co-scientist brouhaha is that it makes us discuss what science *is*, and how to measure its value, impact, quality. — Questions that have been there all along, but many preferred to gloss over.
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Susanne Foitzik @temnothorax.bsky.social · 27/05/2026
Sequential origin of an alternative colony founding strategy driven by two supergenes in Temnothorax ants academic.oup.com/mbe/article/...
academic.oup.com
Sequential origin of an alternative colony founding strategy driven by two supergenes in Temnothorax ants
Abstract. Recent discoveries reveal that many complex intraspecific polymorphisms are shaped by a single supergene that maintains coadapted genetic variant
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Ruprecht Polenz @polenz.bsky.social · 03/05/2026
Da hat jemand die Aufklärung nicht verstanden, der wir unser liberales System der Wahrheitsfindung verdanken
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Susanne Foitzik @temnothorax.bsky.social · 24/04/2026
Save the date and join us next March for the GEM Evolution Meeting😀
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Katie Mack @astrokatie.com · 23/04/2026
When Einstein developed general relativity the closest thing to a practical application that could even be imagined at the time was a slightly more precise description of where to look for the planet Mercury in the sky, and yet now we’d all be literally lost without it. Anyway: fund basic research.
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Peter Jelinek @peterjelinek.eurosky.social · 18/04/2026
"Wir unterrichten bereits in den ersten Semestern, dass Verbrennungsprozesse viel ineffizienter sind als die Erneuerbaren. Und was man jetzt momentan vorhat, ist ungefähr so, als wenn jemand zu euch nach Hause kommt & sagt: Der Induktionsherd, muss raus. Jetzt wird wieder auf offenem Feuer gekocht."
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Christoph Bautz @christophbautz.bsky.social · 17/04/2026
Harald Lesch bringt es auf den Punkt: Viele sind “geschockt, dass wir demonstrieren müssen für den gesunden Menschenverstand, für erneuerbare Energien.” Aber angesichts von Reiches fossiler Lobbypolitik müssen wir das tun - und das werden wir morgen bundesweit. Erneuerbare Energien verteidigen!
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LMU München @lmu.de · 17/04/2026
LMU-Professor Harald Lesch wird Ehrenbürger von München 🎉 Auszeichnung für Wissenschaft, Aufklärung und Engagement. #HaraldLesch #München #Wissenschaft
lmu.de
Harald Lesch wird Ehrenbürger der Stadt München
Die LMU gratuliert ihrem langjährigen Professor Harald Lesch zur Verleihung der Ehrenbürgerwürde, die am 16. April 2026 im Rahmen eines feierlichen Festakts überreicht wurde.
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José Antonio Borrero @borreroja.bsky.social · 15/04/2026
¡Contento de compartir nuestro nuevo artículo sobre el forrajeo de polen en Heliconius himera en @behavecol.bsky.social! 🦋🌼 Exploramos cómo hembras y muchos de H. himera difieren en el forrajeo de polen y rasgos sensoriales. 1/6🧵👇https://academic.oup.com/beheco/article/37/3/arag014/8490681
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José Antonio Borrero @borreroja.bsky.social · 15/04/2026
Excited to share our new paper on pollen foraging in Heliconius himera @behavecol.bsky.social! 🦋🌼 academic.oup.com/beheco/artic... We explored how female and male H. himera differ in pollen foraging & sensory traits. 1/6🧵👇
academic.oup.com
Sexual dimorphism in pollen foraging and sensory traits in Heliconius butterflies
Male and female butterflies often face different ecological and sensory demands, yet how this shapes their foraging behaviour remains unclear. In Heliconiu
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Laura Sophie Dornheim @lsdornheim.eurosky.social · 22/03/2026
Ich radle durch die sonnige Stadt und möchte am liebsten jede Person, die ich sehe, fragen, ob sie schon wählen war. Wenn ihr das als Münchner*innen lest, wart ihr bestimmt schon, oder geht gleich, richtig? #govote
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Robert E. Rollins @robertrollins1892.bsky.social · 19/03/2026
New publication alert! 🥳🍾 With Prof. Dr. Kraiczy's lab, we asked how natural genetic variation affects the function of immune modulatory Borrelia proteins and if this could influence how pathogenic the populations are to humans. Out now in Scientific Reports: doi.org/10.1038/s415...
doi.org
Natural genetic variation impacts complement inhibitory activity of PFam54 orthologs of Asian Borrelia bavariensis - Scientific Reports
European and Asian populations of Borrelia (B.) bavariensis, a causative agent of Lyme borreliosis, substantially differ in their infection dynamics. This is argued to be a byproduct of the unique dem...
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Robert E. Rollins @robertrollins1892.bsky.social · 19/03/2026
Help us find ticks in Germany! NABU has launched a nation wide effort to understand the range expansion of ticks in Germany. With changing climates, tick species have been able to extend their ranges. You can help by reporting tick images as explained below: www.nabu.de/tiere-und-pf...
nabu.de
Zecken melden - NABU
In den letzten Jahren haben sich Zecken in Deutschland weiter ausgebreitet und es sind neue Arten hinzugekommen. Gemeinsam mit Ihnen möchten NABU|naturgucker und wir mehr über das Verhalten und die Ve...
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Dirk Metzler @dirkmetzler.bsky.social · 11/03/2026
This sounds so great that I just have to re-repost it, even though it is competing with our masters program EES at LMU!
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SPP 2349 Gevol @gevol.bsky.social · 09/03/2026
You want to work on Transcriptional Regulation in Beetles 🐞? Join our GEvol Community and work with many great people ➡️ Two open PhD positions in @bfeldmeyer.bsky.social lab in Frankfurt: g-evol.uni-muenster.de/open-positio...
g-evol.uni-muenster.de
Open Positions – GEvol – DFG SPP 2349
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Dirk Metzler @dirkmetzler.bsky.social · 10/03/2026
Two exciting PhD positions for biologists or bioinformaticians in Barbara Feldmeyer's lab at Senckenberg Biodiversity and Climate Research Institute in Frankfurt, one on transcriptional regulation of odorant perception in hymenoptera and... g-evol.uni-muenster.de/open-positio...
g-evol.uni-muenster.de
Open Positions – GEvol – DFG SPP 2349
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Campact e.V. @campact.de · 05/03/2026
3/ Wir kennen alle die Lösung: Erneuerbare Energien! Sie… ☀️ …machen unabhängig von Autokraten 🏭 …schaffen jede Menge Jobs 💶 …bringen langfristig niedrigere Strompreise 🌍 …sind die beste Antwort auf die Klimakrise.
Grafik mit Überschrift „Gegen fossile Abhängigkeit“. Text kritisiert die Bundesregierung dafür, die Energiewende auszubremsen und fordert: Schluss mit Politik für Gas- und Öllobby, Energieversorgung sichern und Energiewende retten. Aufruf, einen Appell an die Bundesregierung zu unterzeichnen.
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MPI for Biology Tübingen & Friedrich Miescher Laboratory @mpi-bio-fml.bsky.social · 05/03/2026
Excited to see our FML Research Group Leader @luisapallares.bsky.social in the latest Max Planck Research! 🎉 The article follows her journey from Colombia to Germany and her work on how genes and environment shape complex traits using fruit flies. Read the full story: www.mpg.de/26180374/W00...
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Sandra Jansen @sj2915.bsky.social · 26/02/2026
Here’s some more: www.nature.com/articles/d41...
nature.com
How to stop the revolving door of German academia
Germany is one of the most popular destinations for students and scholars worldwide, but those pursuing academic careers face significant hurdles to success.
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Robert Reich @rbreich.bsky.social · 26/02/2026
The richest man owns X. The second and third richest men control Google. The fourth richest man owns Facebook, Instagram, and WhatsApp. The fifth richest man owns The Washington Post. And now the sixth richest could soon take over both Paramount and Warner Bros. See the problem here?
nytimes.com
Netflix Backs Out of Bid for Warner Bros., Paving Way for an Ellison Takeover
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Wolf Lab @jochenwolflab.bsky.social · 21/02/2026
Oft Herr Mendel dreams that genes form living matter. They do the latter. doi.org/10.1093/gene...
doi.org
Beyond Mendel: a call to revisit the genotype–phenotype map through new experimental paradigms
Abstract. The long-standing notion that genotypes map to phenotypes through simple one gene–one trait relationships continues to shape both research in the
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Amrei Bahr @amreibahr.bsky.social · 20/02/2026
Gestern hab ich bekannt gegeben, dass ich spätestens 2028 aus der Wissenschaft aussteigen werd — darüber schreibt @evamurasov.bsky.social nun im @tagesspiegel.de. Zig Kommentare & Nachrichten zeigen mir: Sehr viele Wissenschaftler_innen hadern. Bedingungen müssen dringend besser werden! #IchBinHanna
tagesspiegel.de
#IchbinHanna-Gründerin schmeißt hin: Amrei Bahr wurde Juniorprofessorin – und verlässt die Wissenschaft
Mit ihrem Einsatz für bessere Arbeitsbedingungen an Unis wurde Amrei Bahr bekannt und löste eine Bewegung aus, die das Wissenschaftssystem ändern will. Jetzt gab die Juniorprofessorin ihren Ausstieg a...
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EvoBioLMU @evobiolmu.bsky.social · 09/02/2026
@jochenwolflab.bsky.social Where do potentially harmful mutations accumulate? We have an answer in birds. Congratulations Fidel for wonderful paper! doi.org/10.1093/gene...
doi.org
Determinants of mutation load in birds
Abstract. Many mutations have detrimental effects. The mutation load in a population depends on the efficacy of purifying selection in removing deleterious
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LMU München @lmu.de · 09/02/2026
#Photosynthesis 🌿: A team led by #LMU biologist Hans-Henning Kunz has now deciphered the chloroplast ionome of various plant species. Their findings form an important basis for elucidating the regulation of mineral homeostasis in chloroplasts & developing new biotech strategies.
lmu.de
Photosynthesis: new insights into mineral homeostasis of chloroplasts
LMU biologists decipher the ionome of chloroplasts and create the foundations for new biotech strategies.
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Claas Gefroi @claasgefroi.bsky.social · 30/01/2026
Man muss sich das einmal klar machen: Die Staatssekretärin im Bundeswirtschaftsministerium Connemann relativiert wissenschaftliche Erkenntnisse und wischt sie einfach weg. Das ist Querdenkertum und Trumpismus inmitten der Bundesregierung. www.tagesschau.de/inland/innen...
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Auch der Ökonom Martin Wietschel vom Fraunhofer-Institut für System- und Innovationsforschung in Karlsruhe sagt, es sei inzwischen Konsens, dass E-Fuels für Pkw und Lkw keinen Sinn machten. Die Herstellung sei viel zu teuer, so Wietschel, der Wasserstoff würde außerdem für andere Bereiche dringender benötigt.

Staatsekretärin Connemann teilt die Bedenken offenbar nicht. "Manche Wissenschaftler können sich auch täuschen", sagt die CDU-Politikerin im Interview mit Panorama, E-Fuels würden nicht nur eine Nische bedienen, E-Fuels würden Zukunft schreiben.
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Barack Obama @barackobama.bsky.social · 25/01/2026
The killing of Alex Pretti is a heartbreaking tragedy. It should also be a wake-up call to every American, regardless of party, that many of our core values as a nation are increasingly under assault.
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SPP 2349 Gevol @gevol.bsky.social · 07/01/2026
Gevol Job alert: 2 New PhD positions. You want to do Bioinformatics 💻, please check the job Mario Stankes lab in Greifswald, or maybe work on ant venoms 🐜, please check the job in Simon Tragust lab in Halle. These and more open jobs can be found g-evol.uni-muenster.de/open-positio...
g-evol.uni-muenster.de
Open Positions – GEvol – DFG SPP 2349
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Bornberglab @bornberglab.bsky.social · 17/12/2025
📢🪳 New paper alert! Former group members Alina and Mark contributed to a new study just published in Nature Communications. The team generated 47 new high-quality genomes from termites and cockroaches, filling a major gap in available data. Check out the paper here: www.nature.com/articles/s41...
nature.com
Unravelling the evolution of wood-feeding in termites with 47 high-resolution genome assemblies - Nature Communications
Termites, the largest lineage of non-hymenopteran social insects, are important decomposers of plant organic matter in the tropics. Here, the authors sequence the genomes of 45 termites and two cockro...
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SPP 2349 Gevol @gevol.bsky.social · 15/12/2025
GEvol Job Alert: PhD position in Robert Paxtons lab in Halle This research project focuses on the extent to which the origin of eusociality in the socially variable halictid bees is ascribable to changes in gene regulatory mechanisms. Find this and more open positions @ g-evol.uni-muenster.de
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Peter Jukes @peterjukes.bsky.social · 06/12/2025
Here is the whole Trump, Brexit, Russia story neatly summed up for you The battle started about Ukraine, now it’s about big tech monopoly power
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Benoit Nabholz @benoitevol.bsky.social · 04/12/2025
The CNRS is breaking free from the Web of Science www.cnrs.fr/en/update/cn...
cnrs.fr
The CNRS is breaking free from the Web of Science
From January 1st 2026, the CNRS will cut access to one of the largest commercial bibliometric databases, Clarivate Analytics'
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Katharina Hoff @katharinahoff.bsky.social · 29/11/2025
What has to change in the German academic system? In my opinion, achievements should be rewarded. Some countries have criteria for in-house promotions & tenure in place. In Germany, that is very difficult. Our anti nepotism laws make it hard. www.nature.com/articles/d41...
nature.com
How to stop the revolving door of German academia
Germany is one of the most popular destinations for students and scholars worldwide, but those pursuing academic careers face significant hurdles to success.
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Sebastian Höhna @hoehna.bsky.social · 27/11/2025
Deadline soon (end of Nov) for this PhD position in evolutionary genomics/bioinformatics in my group.
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Jun Ishigohoka @junishigohoka.bsky.social · 26/11/2025
www.nature.com/articles/s41...
nature.com
Progressive coevolution of the yeast centromere and kinetochore - Nature
Thousands of centromeres were identified and tracked across two major fungal clades, showing that new centromeres spread progressively and that the kinetochore acts as a filter to determine which new ...
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Dirk Metzler @dirkmetzler.bsky.social · 26/11/2025
PhD position available for theoretical and statistical modeling in my joint @gevol.bsky.social project with @luisapallares.bsky.social on the evolution of transcriptional variability and its role in adaptation and evolutionary innovation. See job-portal.lmu.de/jobposting/6...
job-portal.lmu.de
PhD candidate in biology — theoretical and statistical modeling (m/f/x)
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SPP 2349 Gevol @gevol.bsky.social · 26/11/2025
📢 Job alert: Post-Doc Position in the project "Functional annotation of genomic🧬 innovations in a densely populated clade🪰 with deep learning 💻" Join the GEvol community in a collaborative project between @bornberglab.bsky.social and @katharinahoff.bsky.social lab. 👉 bornberglab.org/post-doc-pos...
bornberglab.org
Post-Doc – bornberglab.org
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Dirk Metzler @dirkmetzler.bsky.social · 12/11/2025
I am also super happy and excited about our joint project with @luisapallares.bsky.social as part of DFP SPP GEvol @gevol.bsky.social !
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Sebastian Höhna @hoehna.bsky.social · 11/11/2025
PhD position available in evolutionary genomics/bioinformatics (hoehnalab.github.io/job_adverts/...). Topic: analyzing gene expression evolution across several firefly species and linking expression changes to genomic architecture. The position is jointly supervised with @anaevolcatalan.bsky.social
hoehnalab.github.io
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EvoBioLMU @evobiolmu.bsky.social · 10/11/2025
@jochenwolflab.bsky.social Check out the latest paper spearheaded by @chyiyin.bsky.social. She explored different methods for target enrichment of DNA extracted from thousands of years old crow bones. Long live ancient DNA! doi.org/10.1111/1755...
doi.org
Performance of Two Custom Probe Kits for In‐Solution Enrichment of Ancient Avian DNA
Ancient DNA (aDNA) analysis remains challenging due to low endogenous DNA content of degraded samples. Hybridisation-based in-solution enrichment has emerged as an effective tool for targeting genomi...
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SPP 2349 Gevol @gevol.bsky.social · 10/11/2025
🎉We are happy to announce that our wonderful GEvol SPP will be funded by @dfg.de for another 3 years. Included are 17 great projects all over Germany with amazing people. You want to be part of this fantastic community? Soon you can find new PhD/Post-Doc positions here & on our website. Stay tuned🎉
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Dirk Metzler @dirkmetzler.bsky.social · 04/11/2025
Cuckoos: Maternal genes determine egg color www.lmu.de/en/newsroom/...
lmu.de
Cuckoos: Maternal genes determine egg color
European cuckoos lay very different eggs depending on the host species. Genetic analyses have revealed how this adaptation is inherited without leading to speciation.
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Justin Merondun @merondun.bsky.social · 30/10/2025
Our new @science.org paper is out! Cuckoos and hosts are locked in a coevolutionary arms race over egg mimicry. But how are these egg types inherited, and could this drive speciation? We sequenced hundreds of genomes to find out! doi.org/10.1126/scie... 🧵1/6
doi.org
Genomic architecture of egg mimicry and its consequences for speciation in parasitic cuckoos
Host-parasite arms races facilitate rapid evolution and can fuel speciation. Cuculus cuckoos are deceptive egg mimics that exhibit a broad diversity of counterfeit egg phenotypes, representing host-ad...
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