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Dave Grainger

@degrainger.bsky.social
1.5K followers 707 following 42 posts

Developmental biologist studying endothelial cell differentiation and heterogeneity Postdoc in the Stone Lab - Institute of Developmental and Regenerative Medicine, Oxford, UK

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Reposted by Dave Grainger
Simon Cleary @simoncleary.bsky.social · 11h
Nikon: '"At this time, we don't see that any rules were violated," it said in a statement.' www.bbc.co.uk/news/article...
bbc.co.uk
Tiny image sparks big backlash in Nikon photo contest
Dr Ning Xu denies he broke the rules of Nikon's annual Small World In Motion contest.
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Dave Grainger @degrainger.bsky.social · 27/08/2026
open.spotify.com/track/2ifYUf...
open.spotify.com
Ain't It The Life
Foo Fighters · There Is Nothing Left To Lose · Song · 1999
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Manx Neurobiologist @garyrlewin.bsky.social · 15/07/2026
For me this paper is a career highlight..truly astonishing biology! www.nature.com/articles/s41...
nature.com
A queen odour mediates reproductive suppression in a eusocial mammal - Nature
Naked mole-rat (Heterocephalus glaber) queens produce isopropyl myristate, a low-volatility ester that high-ranking animals detect and avoid, which alters prolactin and progesterone in other females t...
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Young Embryologist Network @yen-network.bsky.social · 10/06/2026
We are excited to share with you the shortlisted image submissions for the YEN 2026 Image Competition! Public voting is now open, cast a vote for your favourite image here: forms.gle/dxx8SGj2LUtd...
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Dave Grainger @degrainger.bsky.social · 13/05/2026
open.spotify.com/track/2fDVMN...
open.spotify.com
Home
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Dave Grainger @degrainger.bsky.social · 29/04/2026
I have since used CODEX to help me with a relatively complex analysis of microscopy data. It has blown me away with it's ability to write and test code while reasoning the best way to approach a problem. Shouting this into the void in the hopes someone sees it and tries it for themselves
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Dave Grainger @degrainger.bsky.social · 29/04/2026
I attended an AI agents for researchers workshop on Monday and it involved many live demonstrations from researchers at my university. It was honestly shocking how good CODEX was at complex coding tasks (coming from someone who has been pasting their coding errors into ChatGPT for a while now)
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Dave Grainger @degrainger.bsky.social · 17/04/2026
Seeing the dismantling of science in the US reminds us that public trust and support of science in the UK is crucial. There are some recommendations for scientists in this report (and short summary) on how we can better engage people in all parts of society
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Iain Roberts @slowbikeiain.bsky.social · 20/01/2026
Yesterday it was cows using tools, today its penguins using satellite imagery.
Headline: "Scientists discover emperor penguin colony in Antarctica using satellite images"
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Oliver Stone @oliverastone.bsky.social · 20/12/2025
Please check out our job post @biologists.bsky.social! We are recruiting a Postdoc Scientist to develop cutting-edge tools and techniques for bioengineering human lymphatic networks, as part of an interdisciplinary collaboration with the group of Prof Dame Molly Stevens! bit.ly/3La9idq
bit.ly
Postdoctoral position in vascular bioengineering in Oxford, UK - the Node
The Stone Group at the Institute of Developmental and Regenerative Medicine, University of Oxford, is looking for a motivated Postdoctoral Research Scientist to develop tools and techniques that enabl...
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 06/11/2025
Today’s #ScientificImage — “Where Vessels Begin,” comes from @degrainger.bsky.social, a postdoctoral researcher in IDRM's Stone group. 💬"We are working to understand how blood and lymphatic vessels form during embryonic development and how organ-specific characteristics of these vessels arise."
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Dave Grainger @degrainger.bsky.social · 02/11/2025
Our Institute for Desperately Regrowing Moustaches @idrm.ox.ac.uk is raising money for men’s mental health, suicide prevention, and prostate and testicular cancer awareness by growing moustaches. Please donate on our Movember page if you're able! movember.com/t/institute-...
movember.com
Institute of Developmental and Regenerative Medicine (IDRM)'s Mo Space
Movember, the month formerly known as November, is a moustache growing charity event held during November each year that raises funds and awareness for men's health.
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Giulia Boezio @giulia-boezio.bsky.social · 26/10/2025
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions 🧵👇 www.biorxiv.org/content/10.1...
biorxiv.org
Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding
The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...
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Dave Grainger @degrainger.bsky.social · 15/10/2025
BBC News - Pictured: Winning entries for Wildlife Photographer of the Year 2025 - BBC News www.bbc.co.uk/news/article...
bbc.co.uk
Pictured: Winning entries for Wildlife Photographer of the Year 2025
South African photographer Wim van den Heever takes the main prize for his shot
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kostaslekkos.bsky.social @klekkos.bsky.social · 01/10/2025
Do zebrafish regenerate their hearts equally? In our new paper at the @tillymommersteeg.bsky.social lab we uncovered variations in the regenerative response of 7 wt zebrafish strains leading us to identify a critical role of oxidative phosphorylation in long-term heart regeneration. rdcu.be/eI1v5
rdcu.be
Oxidative phosphorylation is required for cardiomyocyte re-differentiation and long-term fish heart regeneration
Nature Cardiovascular Research - Lekkos et al. show that a metabolic switch toward oxidative phosphorylation is required for cardiomyocyte re-differentiation and heart regeneration after injury in...
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Kate Cavanaugh @katecavanaugh.bsky.social · 01/10/2025
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
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Dave Grainger @degrainger.bsky.social · 25/09/2025
Whether you're into photography or not there's something here for everyone. Some amazing shots www.britishphotographyawards.org/2025-shortli...
britishphotographyawards.org
British Photography Awards
The British Photography Awards is a charity oriented photography prize open to all UK residents and British photographers the world over
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Dave Grainger @degrainger.bsky.social · 10/09/2025
Whew the most amazing I've ever seen the sea. Off the coast of Kerry, Ireland
Picture from the edge of a cliff looking along the coast with dark grey rocks sticking out of a turbulent aqua marine sea with lots of foam
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FocalPlane @focalplane.bsky.social · 04/09/2025
ICYMI – Our featured image was this beautiful colour-coded depth projection of the blood endothelial cells of the mouse embryonic thymus & surrounding structures. The image was acquired by David Grainger. Find out about David’s research⤵️ focalplane.biologists.com/2025/08/29/f... #SciArt
focalplane.biologists.com
Featured image with David Grainger - FocalPlane
Featured image with David Grainger - News
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Dave Grainger @degrainger.bsky.social · 05/09/2025
Have a look at my featured image with FocalPlane. It's a thymus, I swear 🦋
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Private Eye Magazine @privateeyenews.bsky.social · 03/09/2025
“I’m not sure I want to give way to the right” From the new Private Eye, in shops now.
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Thiago Carvalho @cyrilpedia.bsky.social · 25/08/2025
Wow 'Here, we present a high-speed blockface volumetric imaging system with an optimized workflow of whole-body clearing, capable of imaging the entire adult mouse at micrometer resolution within 40 h.' www.cell.com/cell/fulltex...
cell.com
High-speed mapping of whole-mouse peripheral nerves at subcellular resolution
A high-speed pipeline enables whole-mouse imaging and mesoscopic analysis of peripheral nerves using transgenic, immunostaining, and viral labeling, providing an effective means to map body-wide struc...
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Dave Grainger @degrainger.bsky.social · 16/08/2025
Giant fiancée took me out for my nearly-birthday
A woman and a man standing next to eachother in a black and white room. An optical illusion makes the woman appear twice the height of the man
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Beth Psaila @bethpsaila.bsky.social · 15/08/2025
Thrilled that our paper is in print @science.org!! *Platelets sequester cell free DNA, including free fetal and tumour-derived DNA* Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
science.org
By sucking up DNA, clot-producing platelets could help diagnose cancer
The cells could be a new source of tumor DNA for liquid biopsies
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Dave Grainger @degrainger.bsky.social · 23/07/2025
Looking forward to the Spa GP this weekend. Ferrari sharing some cool artwork this week
Comic book style drawing of a red formula 1 car driving on a race track with green mountains in the background and orange flowers in the foreground. Written on the floor next to the F1 car is written Spa Francorchamps
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Daniyal Jafree @daniyaljafree.bsky.social · 22/07/2025
Excited to share our new collaborative preprint between @uclnews.bsky.social and @sickkidsto.bsky.social 🥳 We found that kidney lymphatic vessels, an emerging target in kidney diseases, partly arises from the same group of cells that give rise to the kidney www.biorxiv.org/content/10.1... (1/4)
biorxiv.org
Genetic lineage tracing identifies intermediate mesoderm as a novel contributor to mammalian kidney lymphatics
The lymphatic vasculature is essential for fluid homeostasis, immune regulation and possesses diverse organ-specific functions. During development, lymphatic endothelial cells (LEC) arise from multipl...
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Dave Grainger @degrainger.bsky.social · 20/07/2025
I've seen a massive influx of bot-looking accounts following me on here. Almost all only posting about US politics. Hope it doesn't drown out why I joined this platform like it did on twitter
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Reposted by Dave Grainger
Development @dev-journal.bsky.social · 28/05/2025
Register now to attend our #DevPres webinar next week, featuring the winners of the @bsdb.bsky.social poster prize, @shifaant.bsky.social and @giuliapaci.bsky.social, and chaired by Abigail Tucker. 4 June at 15:00 BST us02web.zoom.us/webinar/regi...
Development presents...
Wednesday 4 June 15:00 BST
BSDB poster prize winners. CHair: Abigail Tucker
Giulia Paci University College London - ‘3D cell topology regulates signalling range to promote precise patterning of wing sensory organs’
Shifaan Thowfeequ University of Oxford - ‘Visualising calcium dynamics in the developing embryo: from fertilisation to the first heartbeat’
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 28/05/2025
🎓 The MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies (REACT) is inviting applications for a fully funded DPhil studentship, based at the IDRM. Learn more and apply: lnkd.in/gb-mEX8K @oxforddpag.bsky.social
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Dave Grainger @degrainger.bsky.social · 20/05/2025
My entry SMILE made it into the top ten 😁 Alongside many great entries. My favourite is Minnie's Bow!
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Dave Grainger @degrainger.bsky.social · 19/05/2025
Great evening of talks at #pint25 in Oxford Tech Me Out theme. Very interesting talks from Alex and Jorge from @alpinef1.bsky.social followed by Muhammed Waqas from JLB. Alpine even brought a front wing from their 2024 F1 car! @pintofscience.uk
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Dave Grainger @degrainger.bsky.social · 18/05/2025
Great weekend celebrating @emmarose64.bsky.social's graduation with friends and family. Very proud! 😊
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Young Embryologist Network @yen-network.bsky.social · 02/05/2025
We indeed got many entries!
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Pint of Science UK @pintofscience.uk · 14/04/2025
✨Tickets for #pint25 are now on sale!✨ 🎟Book here 👉 pintofscience.co.uk 👈 🐝🧪👩‍🔬📚🔬👓🧠🐟🫀💫🥼👨‍🔬🔭🧫🦴 🗓19th-21rd May 2025 📍45+ locations across the UK 🗣400 event
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Young Embryologist Network @yen-network.bsky.social · 07/04/2025
YEN Image Competition Update! We already have some amazing contributions from early career researchers from the UK, Switzerland and US. We would love to see contributions from other countries as well! If you can't travel to the conference remember you can always participate online.
World map with YEN Image Competition contributors.
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Molecular Instruments, Inc. @hcrimaging.bsky.social · 28/03/2025
#onlywithHCR: @degrainger.bsky.social, @oliverastone.bsky.social, and their team reveal that lymphatic endothelial cells arise from specialized progenitors. #HCRimaging helped them to visualize endothelial progenitors in whole-mount mouse embryos. Learn more: www.nature.com/articles/s44...
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Biomedical Picture of the Day BPoD @bpodaily.bsky.social · 20/03/2025
Lymphatic vessels traced to their origins from a specialised pool of cells called angioblasts 📷: Irina Lupu @degrainger.bsky.social Nils Kirschnick et al @oliverastone.bsky.social Friedemann Kiefer @ox.ac.uk @uni-muenster.de @naturecvr.bsky.social ➡️: bpod.org.uk/archive/2025...
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Hans schoofs @hansschoofs.bsky.social · 20/03/2025
• Happy to announce that our paper in @nature.com is finally out! Thanks to the perseverance of @taijamakinenlab.bsky.social and our many collaborators we finally pulled it off! A small 🧵 www.nature.com/articles/s41... Laymen video: www.nature.com/articles/d41...
nature.com
Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium - Nature
Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result from continuous...
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the Node @the-node.bsky.social · 11/03/2025
Together with @focalplane.bsky.social, we're having an image competition to accompany the #Biologists100 conference. Thank you everyone who submitted their images. Shortlisting only 15 was tough! Browse through the gallery and vote for your favourite image: thenode.biologists.com/vote-for-you...
thenode.biologists.com
Vote for your favourite image in the Node–FocalPlane image competition - the Node
Browse through the gallery of the 15 shortlisted images and vote for your favourite image by Wednesday 26 March.
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Dave Grainger @degrainger.bsky.social · 11/03/2025
Some great images in this years @the-node.bsky.social image competition. Including my own "Thymus in the Spotlight" image taken in the @idrm.ox.ac.uk Zeiss CoE. Vote for your favorite here: thenode.biologists.com/vote-for-you...
A vibrant abstract image with a network of lines in blue, purple, yellow, and red against a white background. Shape resembles a medical illustration of a woman with a painterly effect
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Maria Diaz de la Loza, Scientific Illustrator @mariadiazillus.bsky.social · 26/02/2025
My first blue update! Sharing my most recent illustration in a scientific journal.Thank you to @oliverastone.bsky.social who contacted me to adapt his concept as the cover for his paper in @naturecvr.bsky.social. These are the original design and the journal version!
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Ben Hogan @benjhogan.bsky.social · 19/02/2025
We have a postdoc position available in the lab! Come and work on lymphatic vascular development and regeneration. We use zebrafish, mouse, cells, tumour models and love imaging, genetics and genomics🔬 Come join us in Melbourne! www.seek.com.au/job/82157187...
seek.com.au
Postdoctoral Fellow Job in Melbourne at Peter MacCallum Cancer Centre - SEEK
The Hogan laboratory is offering work for a highly motivated and skilled postdoctoral fellow in the area of lymphatic development and regeneration.
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Dave Grainger @degrainger.bsky.social · 31/01/2025
www.bbc.co.uk/news/article...
bbc.co.uk
NHS to offer 'groundbreaking' sickle cell gene therapy
The gene therapy Casgevy, which will now be offered to some patients in England, could help people live disease-free, experts say.
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Young Embryologist Network @yen-network.bsky.social · 30/01/2025
Registration and abstract submission for YEN 2025 is officially open! We are looking forward to seeing you at the 17th Young Embryologist Network Conference on the 19th May 2025. Attendence is FREE thanks to our amazing sponsors: @biologists.bsky.social @10xgenomics.bsky.social and Azenta.
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Dave Grainger @degrainger.bsky.social · 26/01/2025
Taking @emmarose64.bsky.social and my mum to their live first rugby games was great. Especially with it being such a good game and Gloucester winning 🍒⚪
Three happy people wearing Gloucester rugby jersey's (cherry and white stripes) stood in front of a rugby pitch.A rugby stadium with two teams playing, a stand full of supporters in the background with the sun setting behind it
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OxfordDPAG @oxforddpag.bsky.social · 23/01/2025
DPAG's Stone Group publishes new research in @naturecvr.bsky.social on the cellular mechanisms underpinning the formation of lymphatic endothelial cells @oliverastone.bsky.social @degrainger.bsky.social Read the paper here www.nature.com/articles/s44...
nature.com
Direct specification of lymphatic endothelium from mesenchymal progenitors - Nature Cardiovascular Research
Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...
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Oliver Stone @oliverastone.bsky.social · 22/01/2025
Very happy to share our work on lymphatic endothelial cell specification, which was published in Nature Cardiovascular Research this week.
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Dave Grainger @degrainger.bsky.social · 20/01/2025
Whew, photos like these certainly aren't going to stem the excitement of Hamilton at Ferrari www.motorsport.com/f1/news/hami...
motorsport.com
Hamilton makes first visit to Ferrari F1 factory ahead of testing debut
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Dave Grainger @degrainger.bsky.social · 16/01/2025
It's also defintely worth reading the news & views written by Tatiana Petrova and Valeria Orlova for more details on how our work fits within the field and the potential impacts it could have www.nature.com/articles/s44...
nature.com
Paraxial mesoderm as a direct gateway to lymphatic endothelial cells - Nature Cardiovascular Research
The origins of mammalian lymphatic vessels have been debated since the early twentieth century; recent data are shifting the balance toward a less widely accepted view.
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Dave Grainger @degrainger.bsky.social · 13/01/2025
✨Excited to share our work revisiting the developmental origins of mammalian lymphatic endothelial cells.✨ A summary of our key findings using scRNA-seq, snMultiome-seq and imaging to show the direct specification of mesenchymal progenitors to LECs🧵 #blutorial #blabstract tinyurl.com/LECspec
tinyurl.com
Direct specification of lymphatic endothelium from mesenchymal progenitors - Nature Cardiovascular Research
Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...
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