iiinova — where your digital self keeps evolving

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 22/07/2026

Clinical research and patient care go hand in hand. Hear Dr Fatima Dhalla from the Holländer Group discuss why in this excellent interview.

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 17/07/2026

The Oxford-ZEISS Centre of Excellence in Biomedical Imaging between @kiroxford.bsky.social and the Institute of Developmental & Regenerative Medicine has become the first to acquire the new ZEISS Lightfield 4D system. Read more: www.idrm.ox.ac.uk/news-and-fea...

171

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 24/06/2026

We were delighted to bring colleagues together to celebrate Prof Paul Riley's election to the Fellowship of the Royal Society. In true IDRM fashion, Paul used the occasion to recognise the many researchers, collaborators and colleagues who have contributed to the Institute's success.

Scientists gathered at the IDRM cafe to celebrate. Many people with their backs to the camera.

Left to right, Prof Matthew Wood, Prof Paul Riley, and Prof Carlo Rinaldi smile at the camera.

120

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 11/06/2026

How do immune cells help heal the heart? In the latest episode of the @stemcellpodcast.com, Dr. Simões @simoesfilipa.bsky.social, Group Leader at IDRM and Co-Director of the Oxford Organoid Hub, discusses her research on how macrophages shape heart development, repair, and regeneration.

130

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 09/06/2026

In a new expert commentary, Associate Professor Thomas Roberts discusses a paper published in Gene Therapy, which examines the progress and challenges of AAV microdystrophin gene replacement therapies for #DuchenneMuscularDystrophy. Read more: tinyurl.com/2rzbyv6s

A scientist looking through a microscope with labe equipment around her

110

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 27/05/2026

We are excited to share that Professor Paul Riley has been elected to the Fellowship of the Royal Society, the UK’s national academy of sciences, for his outstanding contribution to regenerative medicine and cardiovascular science. www.idrm.ox.ac.uk/news-and-fea... @oxforddpag.bsky.social

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 14/04/2026

The Oxford-ZEISS CoE in Biomedical Imaging, between the IDRM and @kiroxford.bsky.social at @ox.ac.uk, in collaboration with @zeiss-microscopy.bsky.social, is developing a new cutting-edge imaging technology: Selective Plane Illumination Lattice Light Sheet Microscopy. 🔗https://tinyurl.com/mu6xvpwc

140

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 26/03/2026

📢Exciting opportunity for postdocs! The IDRM is offering a Transition Fellowship for outstanding researchers at an intermediate/career development stage. Apply now: lnkd.in/eYkYUAhB #FellowshipOpportunity #Postdoc #InterdisciplinaryResearch @paediatrics.ox.ac.uk

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/03/2026

Congratulations to Filipa Simões and team on their new publication 👏 #regenerativemedicine #zebrafish #heart

010

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 18/03/2026

Spring has arrived at the IDRM! As research in developmental biology and regenerative medicine pushes boundaries within IDRM's laboratories, our scientists can take a look outside and enjoy the view of the blossoming trees in our Japanese garden. 🌸 @ox.ac.uk

011

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 10/03/2026

New research from the Roberts Group @ribomedicine.bsky.social at IDRM explores a new way to increase the body’s own production of BDNF, a key brain protein involved in neuron health, learning and memory. Read the paper: tinyurl.com/ydwxk49d

000

Reposted by Institute of Developmental & Regenerative Medicine

Filipa Simões @simoesfilipa.bsky.social · 02/03/2026

What a pleasure to host @hsiuchuanlin.bsky.social @crg.eu to @idrm.ox.ac.uk @oxforddpag.bsky.social! We discussed in much depth novel technologies pushing forward the engineering human cell fate space- looking forward to exciting collaborations 🤩 And always a treat to visit @jesusoxford.bsky.social!

051

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/02/2026

Spring has arrived at the IDRM just in time for Green Action Week! We are taking action by promoting our book swap, recycling, and Beauty Banks sustainable initiatives. Our bug houses made for pollinators are spring-ready too — with a ladybird already spotted 🐞 #GreenActionWeek #Sustainability

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 11/02/2026

International Women and Girls in Science Day 👩‍🔬✨ We’re proud to support brilliant women at the IDRM, including Dr Andia Redpath, Dr Inhye Park, Dr Sophie Payne and Dr Susann Bruche, who recently took part in the EMBO Laboratory Leadership Course. Read more 👉 tinyurl.com/mrxurm52

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 05/02/2026

On #TimeToTalkDay, we’re proud to support open conversations about mental health. Will Vaulks, who recently gave a talk at the IDRM, and Prof Willem Kuyken remind us that sharing experiences can help reduce stigma around mental health challenges. 📽️ www.youtube.com/watch?v=8Hkd...

youtube.com

Time to talk

YouTube video by University of Oxford

011

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 16/01/2026

In December, we hosted the EMBO Lab Leadership Course with NDM and the Dunn School of Pathology. We spoke to Dr Sophie Payne, Dr Susann Bruche, Dr Inhye Park and Dr Andia Redpath about what they learned about leadership and leading their own research teams. Read more: tinyurl.com/mrxurm52

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 16/12/2025

This week’s scientific image, submitted by the Holländer Lab, is titled “The birth of immunity: spatial transcriptomics illuminating the thymus at E14.5.” The image uses spatial transcriptomics to visualise gene expression patterns across the embryonic thymus at day 14.5.

010

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 11/12/2025

This week’s scientific image, created by Ehsan Razaghi, DPhil student, Simões lab, is titled “Immune-mediated spatial orchestration of cardiac regeneration in zebrafish, 5 days post cryoinjury.” His research focuses on the role of the immune system in heart regeneration after myocardial infarction.

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 10/12/2025

A huge congratulations to Joe Day, former Communications & Operations Apprentice and current Business Development & Engagement Officer at the IDRM, on winning the Shining Star Apprentice Award at the 2025 University of Oxford Apprenticeship Awards!

010

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 04/12/2025

This week’s scientific image, contributed by Dr Emma Haberman from the Riley and Holländer groups, is titled “Atrial Architecture.” Her work investigates the role of T cell-mediated autoimmunity in the progression of heart failure after myocardial infarction.

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 28/11/2025

New from Dr Matthew Stower and the Srinivas Group at IDRM 👇 Calcium signalling turns out to be essential for setting up the embryo’s anterior-posterior body axis. Using light-sheet microscopy, the team captured calcium activity in early mouse embryos. Read more: tinyurl.com/5999kkm8

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 27/11/2025

This week's scientific video, created by Dr Shifaan Thowfeequ from the Shankar Srinivas lab, is titled “Chasing the wave – in search of the origins of the first heartbeat.” The video captures the mechanical and chemical dynamics of an embryonic chick heart as it first forms and starts to beat.

091

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/11/2025

Thanks to everyone who joined us for last week’s Get To Know Each Other event at the IDRM, and to all our fantastic speakers and poster presenters who made the afternoon such a success!

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 20/11/2025

This week’s featured scientific image, "From blueprint to beating - engineering human cardiac development in a dish," comes from Selin Tüzüner (Simões Group), whose work was selected as a finalist in the BHF Reflections of Research competition. Read more: lnkd.in/dQ4rZR9t #ScientificImaging

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 19/11/2025

✨ Monthly Featured Member ✨ Meet Mary Deadman, who recently retired after an incredible 44 years at the University, most recently as Laboratory Manager for the Holländer Group. Mary has supported countless projects and colleagues throughout her career. 🔗Read more: shorturl.at/SWhc5

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 13/11/2025

This Christmas, we’re teaming up with the Department of Paediatrics to support #Sleigh2Give and bring festive cheer to children in hospitals and families across Oxfordshire. 🎁✨ Donate brand new, unwrapped gifts by 12 Dec to help make the holidays a little brighter.

011

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 12/11/2025

Today’s scientific image of the week, “Cellular Hummingbird”, comes from Elizabeth Figueroa-Juárez. 🧫 She’s modelling atherosclerosis in vitro using hiPSC-derived endothelial cells. ✨ The colours and shape reminded her of hummingbirds—“gods’ messengers from the afterlife,” in Mayan legend.

010

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 06/11/2025

Today’s #ScientificImage — “Where Vessels Begin,” comes from @degrainger.bsky.social, a postdoctoral researcher in IDRM's Stone group. 💬"We are working to understand how blood and lymphatic vessels form during embryonic development and how organ-specific characteristics of these vessels arise."

001

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 03/11/2025

Last week's spooky creations, courtesy of IDRM's Mommersteeg Group, were carved just in time for Halloween! @tillymommersteeg.bsky.social

022

Reposted by Institute of Developmental & Regenerative Medicine

Dave Grainger @degrainger.bsky.social · 02/11/2025

Our Institute for Desperately Regrowing Moustaches @idrm.ox.ac.uk is raising money for men’s mental health, suicide prevention, and prostate and testicular cancer awareness by growing moustaches. Please donate on our Movember page if you're able! movember.com/t/institute-...

movember.com

Institute of Developmental and Regenerative Medicine (IDRM)'s Mo Space

Movember, the month formerly known as November, is a moustache growing charity event held during November each year that raises funds and awareness for men's health.

021

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 30/10/2025

Rise of the Arteries — a lightsheet image capturing the intricate vascular network of a developing mouse heart. By visualising endothelial and smooth muscle cells in 3D, researchers at IDRM reveal the beauty of coronary vessel formation. 📷 Credit: Konstantinos Miti & Polen Bareke

0304

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 02/10/2025

New research led by @klekkos.bsky.social and @tillymommersteeg.bsky.social at the IDRM and DPAG has uncovered an essential role for oxidative metabolism in heart regeneration. Read the full paper here: www.nature.com/articles/s44... Read the overview of the study: tinyurl.com/2syythet

022

Reposted by Institute of Developmental & Regenerative Medicine

Tilly Mommersteeg @tillymommersteeg.bsky.social · 01/10/2025

More new work from the lab! @idrm.ox.ac.uk @oxforddpag.bsky.social Do all zebrafish regenerate their hearts equally? Also featuring the Mexican cavefish☺️ Thanks to all co-authors and especially the incredibly talented DPhil student Kostas Lekkos who drove the project. #zebrafish #heartregeneration

2158

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 28/08/2025

Meet Antonio Garcia Guerra, a Postdoctoral Research Scientist in the Rinaldi Group, and our August featured member. Antonio's research focuses on cell-specific gene editing in neuromuscular disease. Find out more about his research: www.linkedin.com/feed/update/... @oxfordpaediatrics.bsky.social

010

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 18/08/2025

How do you turn cutting-edge science into a business idea? We spoke with Dr Sophie Payne (IDRM, DPAG), a postdoctoral researcher, about her journey on the Oxford Venture Builder, where she pitched her enhancer-based gene therapy idea. Read the full interview: lnkd.in/dx27XkV8

020

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 11/08/2025

🎉Congratulations to the IDRM's Professor Sarah De Val on being awarded the title of Professor of Cardiovascular Science by the University of Oxford 🎉 #CardiovascularScience #AcademicAchievement #WomenInSTEM

Square photo showing the head and shoulders of a woman against a blurred background and outlined by a red and yellow gradient border. On the right hand sign is white text on a blue background that reads: Professor of Cardiovascular Science. Congratulations to Sarah De Val, Group Leader within the IDRM Cardiovascular Theme, who has been awarded the title of Professor of Cardiovascular Science by the University of Oxford. To the bottom left are logos for the Institute of Developmental & Regenerative Medicine, and for the University of Oxford.

010

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 30/07/2025

🎉Huge congratulations to Dr Nancy Stathopoulou, IDRM Transition Fellow @oxfordpaediatrics.bsky.social who has been awarded the BHF Intermediate Science Research Fellowship by the @thebhf.bsky.social. Nancy’s work focuses on epigenetics in cardiac development and congenital heart disease.

030

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/07/2025

👋Meet Konstantinos Lekkos, a DPhil Student in the Mommersteeg group, and our most recent featured member. Kostas' research focuses on the role of oxidative metabolism in zebrafish heart regeneration. Find out more about his research: www.linkedin.com/feed/update/... @oxforddpag.bsky.social

011

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 21/07/2025

🎉 Congratulations to Konstantinos Lekkos, a 2nd year DPhil student in the Mathilda Mommersteeg Group. Kostas won first prize at this year’s Oxford MRC-DTP Symposium with his talk on a novel discovery in zebrafish metabolism and heart regeneration. @oxforddpag.bsky.social

031

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 08/07/2025

🚨 The Simões Group is hiring! Join Filipa's team here at the IDRM as a Research Assistant and help advance cutting-edge cardiovascular regeneration research. 🔗 Apply now: lnkd.in/eKiSHWht 📅 Deadline: Midday 1st August 2025

lnkd.in

This link will take you to a page that’s not on LinkedIn

031

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 04/07/2025

Tomorrow is #ResearchAppreciationDay2025! On the final day of our countdown, we’re spotlighting new work from the Thomas Roberts Group (Ahlskog et al.) that challenges a proposed strategy for upregulating therapeutically relevant genes. 🔬 Study: tinyurl.com/4sd3kc86 📰 Story: tinyurl.com/mka7f3j5

tinyurl.com

A new study challenges a potential gene-activating mechanism using antisense oligonucleotides

A new study from the Roberts Group, Ahlskog et al., published in Molecular Therapy: Nucleic Acids, challenges the therapeutic potential of a mechanism previously thought to upregulate protein

000

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 03/07/2025

It is day 3 of our #ResearchAppreciationDay2025 countdown! Dr Filipa Simões and team reveal how immune cells shape the heart from the earliest stages and guide regeneration in species like zebrafish. 🔬 Read the review: shorturl.at/kIYBf

053

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 02/07/2025

Next up in our countdown to #ResearchAppreciationDay2025, we are spotlighting public engagement at the IDRM! IDRM researchers took part in Pint of Science 2025, bringing research and more to local Oxford pubs. Thanks to everyone who helped make it happen! 🔗 Read more: shorturl.at/z3yUI

010

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 01/07/2025

🔬 Research Appreciation Day 2025, Saturday, July 5th, is just around the corner. To mark the occasion, we will spotlight a different project from the IDRM each day until Saturday in our very own Research Appreciation Week!

100

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/06/2025

👋Meet Claudio Cortes Rodriguez, a Postdoctoral Research Fellow in the Riley group, and our most recent featured member. Claudio's research focuses on uncovering the cause of defects in the heart wall. Find out more about Claudio's research: lnkd.in/ebKNJ-zE @oxforddpag.bsky.social

020

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 19/06/2025

This #CleanAirDay, we’re highlighting the small changes and big ambitions shaping sustainability at the IDRM. Yesterday’s biodiversity walk through the Lye Valley was a good reminder of what we’re working to protect: clean air, healthy ecosystems, and time to connect with nature.

042

Reposted by Institute of Developmental & Regenerative Medicine

Filipa Simões @simoesfilipa.bsky.social · 11/06/2025

Truly heart galore here at @thebhf.bsky.social Reflections of Research competition! My vote goes to @selintuzuner.bsky.social beautiful cardiac organoid!! Have you voted yet? @idrm.ox.ac.uk @oxforddpag.bsky.social @ox.ac.uk #OxfordOrganoidHub

052

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 09/06/2025

Exciting news! Dr Jacinta Kalisch-Smith, @jkalism.bsky.social, has been awarded a BHF fellowship to explore how placental blood vessels support fetal growth and development. Her research could change how we detect and prevent complications during pregnancy. 🔗 Read more: shorturl.at/OVzqq

031

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 28/05/2025

🎓 The MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies (REACT) is inviting applications for a fully funded DPhil studentship, based at the IDRM. Learn more and apply: lnkd.in/gb-mEX8K @oxforddpag.bsky.social

001

Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 27/05/2025

Find out how IDRM researchers raised over £1,300 for Muscular Dystrophy UK earlier this month through the Oxford Town & Gown 10k race and fundraising events. Their combined efforts helped raise awareness and support vital research into muscle-wasting conditions. Read more: shorturl.at/rP9RK

shorturl.at

IDRM Researchers Raise Over £1,300 for Muscular Dystrophy UK at Oxford Town & Gown 10k Race

On Sunday 11 May, researchers from the MDUK Oxford Neuromuscular Centre, based at the Institute of Developmental & Regenerative Medicine (IDRM), joined more than 6,000 participants in the historic

000