Sign in

Daniel Yu

@danielsyu.bsky.social
860 followers 1K following 13 posts

Postdoc in the Banfield lab @ John Innes Centre | PhD in the Williams lab @ ANU | Plant immune receptor engineering 🌾 | Fungal effectors 🍄 | Structural biology 💎 | 🇦🇺

PostsRepliesMedia
Reposted by Daniel Yu
Adam Bentham @adamrbentham.bsky.social · 30/09/2026
🚨 Please share! 🚨 I'm recruiting a fully funded 4-year Gatsby Sainsbury PhD studentship at Durham! 🌱🤖 Designing plant immune receptors from scratch, combining AI protein design with structural biology and plant immunity. If you're interested please get in touch! benthamlab.org shorturl.at/U2PdV
benthamlab.org
Bentham Lab — Durham University
Bentham Lab, Centre for Programmable Biological Matter, Durham University. Structural biology and de novo protein design applied to host-pathogen interactions, plant immunity, and neglected tropical d...
02935
Reposted by Daniel Yu
John Innes Centre @johninnescentre.bsky.social · 25/09/2026
PRESS RELEASE - Can this biotech innovation halt the destructive march of a cereal killer? 🌾🦠 A UK-led research collaboration has taken a significant step in the global effort to protect crops from the devastating wheat fungus pathogen
okt.to
Can this biotech innovation halt the destructive march of a cereal killer? | John Innes Centre
A UK-led research collaboration has taken a significant step in the global effort to protect cereal crops from the devastating blast fungus pathogen...
143
Reposted by Daniel Yu
yuxuan-xi.bsky.social @yuxuan-xi.bsky.social · 11/07/2026
Our new preprint is out! Using AI-guided design (RFdiffusion + ProteinMPNN), we engineered a plant immune receptor to recognise non-cognate pathogen effectors. Huge thanks to our amazing co-authors for making this possible! doi.org/10.64898/202...
doi.org
Computational design of de novo integrated domains enables rational control of pathogen effector recognition in plant NLR immune receptors.
The rapid evolution of plant pathogens poses a persistent threat to global agricultural sustainability, often outpacing the discovery and deployment of natural disease resistance genes. While bioengin...
04526
Reposted by Daniel Yu
Mitchell Sorbello @mitchsorbello.bsky.social · 16/01/2026
Hello bluesky
141
Reposted by Daniel Yu
Gitta Coaker @gittacoaker.bsky.social · 16/12/2025
Tandem Kinases containing HMA domains can be engineered to sense additional effectors. Parallels with NLR HMA engineering and highlights the versatility of this interesting integrated domain. www.biorxiv.org/content/10.6...
biorxiv.org
Engineering plant tandem kinase immune receptors expands effector recognition profiles
Plant intracellular immune receptors are widely deployed in breeding to protect crops from disease. In addition to nucleotide-binding leucine-rich repeat receptors (NLRs), tandem kinase proteins (TKPs...
0102
Reposted by Daniel Yu
Gitta Coaker @gittacoaker.bsky.social · 17/12/2025
Another exciting preprint! Two additional HMA-TKP sensors from wheat and barley, swapping HMAs can confer recognition specificity. Evo analyses supporting HMA-TKP has differentiated to recognize different effectors through HMA diversification. other links below. www.biorxiv.org/content/10.6...
biorxiv.org
Evolution of HMA-integrated tandem kinases accompanied by expansion of target pathogens
Tandem kinase proteins (TKPs) are an emerging family of plant intracellular immune receptors that offer potential for developing novel disease resistance. We cloned Rmo2 and Rwt7, genes for resistance...
1157
Reposted by Daniel Yu
mjbanfield.bsky.social @mjbanfield.bsky.social · 16/12/2025
Super-happy sharing my Lab's new work on engineering plant HMA-containing tandem kinase immune receptors. Congrats to all authors (@danielsyu.bsky.social and @njw33.bsky.social on here). Work only possible in collaboration with Soichiro Asuke. See linked paper to follow! bsky.app/profile/bior...
0156
Daniel Yu @danielsyu.bsky.social · 16/12/2025
Excited to share our #plantimmunity preprint on engineering cereal TKPs www.biorxiv.org/content/10.6... A short thread below 👇
biorxiv.org
Engineering plant tandem kinase immune receptors expands effector recognition profiles
Plant intracellular immune receptors are widely deployed in breeding to protect crops from disease. In addition to nucleotide-binding leucine-rich repeat receptors (NLRs), tandem kinase proteins (TKPs...
12210
Daniel Yu @danielsyu.bsky.social · 01/12/2025
Excited to share our review on structure-based engineering of NLRs in plant immunity. We also have some cool plant immunity engineering stories coming out this month so watch this space! #plantimmunity #nlr www.sciencedirect.com/science/arti...
sciencedirect.com
Architects of plant immunity: Structure-informed strategies for engineering plant nucleotide-binding leucine-rich repeat receptors
Diseases caused by plant pathogens are a major factor decreasing crop yields that lead to food insecurity. To protect against pathogen threats, plants…
052
Reposted by Daniel Yu
Peter Solomon @plantpathpete.bsky.social · 20/08/2025
Registrations are rolling in for the 2025 Stromlo Plant Pathology meeting in Canberra (Nov 27–28)! Secure your spot! Speakers: @yasukadota.bsky.social, Cecille Segonzac, @thamlab.bsky.social, @yichangsung.bsky.social, Tek Tay & @danielsyu.bsky.social. Register at tinyurl.com/3e3tx9j2 #strompath25
tinyurl.com
10th Stromlo Plant Pathology Conference | wheatbiosecurity
01613
Daniel Yu @danielsyu.bsky.social · 17/07/2025
Super excited to be giving a talk at #2025ISMPMI today in the Synthetic biology concurrent session from 15:15 - 15:35! Come along if you’re interested in engineering Tandem Kinase Proteins
0103
Reposted by Daniel Yu
Christine Faulkner @pdchristine.bsky.social · 16/07/2025
GROUP LEADER VACANCY JIC is recruiting a Group Leader in Discovery Plant Sciences. If you think your research would synergise and thrive at JIC, please apply. www.jic.ac.uk/vacancies/gr...
jic.ac.uk
Group Leader in Discovery Plant Sciences | John Innes Centre
The John Innes Centre (JIC) seeks a visionary Group Leader to lead research on Discovery Plant Science.
16689
Reposted by Daniel Yu
Yi-Chang Sung (宋宜璋) @yichangsung.bsky.social · 25/04/2025
Our Research Briefing on the tandem kinase proteins paper is online now! Curious about the story behind our TKP paper? 📄 Research Briefing: www.nature.com/articles/s41... 📄 Research article: www.nature.com/articles/s41...
nature.com
A plant dual-kinase protein traps a pathogen effector to trigger immunity - Nature Genetics
Tandem kinase proteins (TKPs) are key regulators of plant immunity. We found that RWT4, a wheat TKP, confers resistance to the fungal pathogen Magnaporthe oryzae by directly recognizing the effector A...
0136
Reposted by Daniel Yu
Simon Williams @williamsanu.bsky.social · 28/02/2025
Its out.... Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors | Science www.science.org/doi/10.1126/... A wonderful collaboration with the Schaffrath @rwth.bsky.social and Oliveira-Garcia groups! Huge credit to Carl Mcombe and Alex Wegner.
science.org
Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors
Inorganic phosphate (Pi) is essential for life, and plant cells monitor Pi availability by sensing inositol pyrophosphate (PP-InsP) levels. In this work, we describe the hijacking of plant phosphate s...
14117
Reposted by Daniel Yu
Megan McDonald @mcdonaldmeganc.bsky.social · 07/12/2024
HI old friends! Finally took the leap here to say I have several open positions going in my lab at the moment (and more to come). 1) PhD studentship in collaboration with the Royal Horticultural Society (genomics) 2) Biochemistry Postdoc to understand how Starships move Check out the links below!
47650
Reposted by Daniel Yu
Mauricio Contreras @mpcontreras.bsky.social · 04/12/2024
If you're from the UK and are looking for a PhD, don't miss out on this fantastic opportunity! Amazing lab and amazing project!
065
Daniel Yu @danielsyu.bsky.social · 23/11/2024
Excited for more #sciart! Here is a #blender render of a small #fusarium effector I solved during my PhD
1121
Reposted by Daniel Yu
The Sainsbury Laboratory @thesainsburylab.bsky.social · 18/11/2024
In case you missed it, here is the TSL Autumn Symposium 2024 in full 🍿
061
Reposted by Daniel Yu
Frank Menke @frankmenke.bsky.social · 18/11/2024
📣 PhD opportunity at @thesainsburylab.bsky.social Norwich, UK. "Investigating host penetration by the rice blast fungus" with Dr Frank Menke and Nick Talbot @FrankMenke.bsky.social @talbotlabtsl.bsky.social Apply before 25 Nov 2024! ⬇️ biodtp.norwichresearchpark.ac.uk/projects/inv...
03828
Reposted by Daniel Yu
Kate Michie @kmichie.bsky.social · 17/11/2024
So many keen peeps interested in structural biology.. we have a new unit cell. 🧶🧬 go.bsky.app/HByHiW6
146125
Reposted by Daniel Yu
Razvan Borza @rborza.bsky.social · 16/11/2024
I created this Starter Pack for PhDs and Postdocs in Structural Biology to help connect with colleagues who share similar interests and concerns in the field. Feel free to recommend people or yourself! I'll be adding people 💪🏼😁 bsky.app/starter-pack...
265722
Reposted by Daniel Yu
Marc Somssich @somssich.bsky.social · 16/11/2024
Hello new Plant Scientists, To get you started, the two #PlantScience Research #StarterPacks will connect you to other Scientists & relevant feeds: 1) go.bsky.app/8Zfmwf7 2) go.bsky.app/3NcqRCE You can find more relevant Plant Science feeds here: bsky.app/profile/soms... Further... 1/2
34630
Daniel Yu @danielsyu.bsky.social · 15/11/2024
First post on bluesky! Sharing some photogenic protein crystals I got a few months back 💎. Shame they didn’t diffract as well as they look
071
Reposted by Daniel Yu
Pierre Grognet @pierregrognet.bsky.social · 14/11/2024
Hi everyone, I created a starter pack for all fungal biologists. Tell me who I should add or if you want to be part of it! #fungi go.bsky.app/12PCCjU
93214