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Mitchell Sorbello

@mitchsorbello.bsky.social
24 followers 37 following 3 posts

PhD candidate in the Kobe Lab at The University of Queensland, Studying TIR domains in plant immunity

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Reposted by Mitchell Sorbello
parkergroup.bsky.social @parkergroup.bsky.social · 09/06/2026
TIRs are key regulators of plant immunity, but the role of conserved TIR-only proteins has remained unclear. Here, we compare TIR-only proteins from Arabidopsis and barley and show that they share a conserved role in plant immunity. www.biorxiv.org/content/10.6...
biorxiv.org
Conserved TIR-only proteins drive transcriptional defense and basal immunity in dicot and monocot plants
Toll/interleukin-1/resistance (TIR) domain NADase enzymes signal in plant immunity by producing ribosylated nucleotide second messengers which activate EDS1 dimer-helper NLR pathways to restrict patho...
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Mitchell Sorbello @mitchsorbello.bsky.social · 07/02/2026
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Mitchell Sorbello @mitchsorbello.bsky.social · 16/01/2026
Hello bluesky
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