Detailed guide describing how to accurately detect deamidation in bottom-up proteomics datasets.

In a recent Cell paper, Maurais et al. show that genomic instability drives human cells to transfer fragmented chromosomes to neighbors via tunneling nanotubes (TNTs), with heritable functional consequences, raising fundamental questions about intercellular communication, genome surveillance, and cancer evolution.

Garge et al. use experimentally matched mass spectrometry and RNA-sequencing to quantify proteins, phosphosites and transcripts across four key stages of human and mouse gastruloid development.

AlphaGenome, a deep learning model that inputs 1-Mb DNA sequence to predict functional genomic tracks at single-base resolution across diverse modalities, outperforms existing models in variant effect...

Liam Ramos' innocence, like the innocence of all kids, is unimpeachable. The visuals of his arrest are excruciating.

Schooley et al. find that mitotically bookmarked loci drive a transient chromosome folding state during G1 entry that is subsequently modulated by factors inherited through the cytoplasm.

James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.

Accurate spectral libraries are essential for analyzing data-independent acquisition (DIA) proteomics data. Here, the authors present Carafe, which trains on DIA data to build experiment-specific spec...

Early last year, the city signed a $2.7 million lease extension to continue using a hotel’s rooms as shelter space. Yet despite committing to pay the rent, the city stopped sending people there.

Rookie right-hander Cam Schlittler struck out 12 as he shut down Boston with 100 mph heat, and the New York Yankees took advantage of a pair misplays in a four-run fourth inning to beat the Red Sox 4-0 for a 2-1 AL Wild Card Series win and a Division Series matchup against Toronto.

YouTube video by Stowers Institute for Medical Research

Rather than steer the nation's top students toward the most lucrative careers, schools could help them build meaningful lives.

DNA replication is molecularly asymmetric, due to distinct mechanisms for lagging and leading strand DNA synthesis. Whether chromatin assembly on newly replicated strands is also asymmetric remains un...

Dr. Mary-Claire King was the first to link a gene to hereditary cancer risk with the identification of BRCA1. She was just getting started.