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Nicolas Fernandez

@cornhundred.bsky.social
2K followers 4.6K following 74 posts

Computational biology with a focus on single-cell/spatial biology & data visualization. I usually post about bikes and urbanism 🚲 🏪 🧬

PostsRepliesMedia
Reposted by Nicolas Fernandez
Maksim Kalutskii @maksimkalutskii.bsky.social · 23/09/2026
Excited to share our new preprint! 📜 Here, we used CALVADOS and ultra-CG models to show how the kinetochore establishes a robust attachment to the dynamic microtubule end. Spoiler: IDRs 🧵 1/n www.biorxiv.org/content/10.6...
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Bromptonymous 🇨🇦 @bromptonymous.ca · 13/09/2026
“Bruh, these bike lanes are social engineering.“ - I know.
Freedom on a bike.
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Hao Yin @haoyin.bsky.social · 14/09/2026
MILK Multi-resolution Integration of Large-scale and high-dimensional Kernel information Biological architecture seems better preserved than UMAP/t-SNE across scales on one hierarchical tree😎 Allow interrogation of different clade sizes along the tree🥸 bioRxiv 2026 www.biorxiv.org/content/10.6...
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Robin Wigglesworth @robinwigglesworth.ft.com · 01/09/2026
Me 🤜 🤛 @fmckenna.bsky.social Great long chat about journalism, bonds, repo and all the good stuff. Plus, A Fabulous Debt of course, and why preorders are important (have i mentioned that in the past 24 hours?) thedig.substack.com/p/a-fabulous...
thedig.substack.com
A Fabulous Debt: Video interview with author, FT Editor Robin Wigglesworth
FT Alphaville Editor Robin Wigglesworth talks to me about his new book, “A Fabulous Debt”, available on September 29.
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Nicolas Fernandez @cornhundred.bsky.social · 29/08/2026
What neighborhoods emerge if you cluster bike share stations based on their destination probabilities? We calculated and visualized these neighborhoods using Celldega's neighborhood module and Clustergram viz 🚲🚲🚲 #citibike #bluebike #capitalbikeshare #divvy cornhundred.github.io/bike_network...
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Fietser Brandon @americanfietser.bsky.social · 23/08/2026
For the Americans whining about gas prices as they constantly keep having to fill up their 4-wheeled tanks for basic participation in society, this is the equivalent of $8.91/gallon. We don't have high gas prices, we have oversized vehicles and no other options in mobility.
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Tom Flood @tomflood.bsky.social · 23/08/2026
better.
person on a cargo bike
red background
CHORES repeated in blue
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Nicolas Fernandez @cornhundred.bsky.social · 19/08/2026
We're excited to share our new preprint, Celldega: Integrated Toolkit for Visualization and Analysis of Spatial Data! Celldega is an open-source framework that tightly couples scalable, interactive visualization (>1M cells and >1B transcripts) with spatial-omics analysis #Xenium #StrataMap #Atera
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bioRxivpreprint @biorxivpreprint.bsky.social · 18/08/2026
Celldega: Integrated Toolkit for Visualization and Analysis of Spatial Data www.biorxiv.org/content/10.64898/20…
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Fietser Brandon @americanfietser.bsky.social · 09/08/2026
Another day, another account peddling this bullshit. They don't realize this just permanently entrenches car infrastructure, forced car dependency, and all the waste and pollution that comes with it. Basic critical thinking makes it easy to distinguish greenwashing from actual good policy.
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Darren Buck @bikepedantic.bsky.social · 08/08/2026
Please please please finish the job Evan started two years ago, 25th Middlesex voters
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Darren Buck @bikepedantic.bsky.social · 05/08/2026
Camberville finally has some trail-oriented retail… and no trail. @cornhundred.bsky.social tipped us off to Art’s Creamery (so good!), open for two months next to the Community Path which has been closed for nine-ish months. Stop by and support them during what must be a tough opening season.
An ice cream shop on the right, closed trail on the left
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Laura G Mitchell @lauragmitchell.com · 03/08/2026
Naysayers re: biking for transportation in Minneapolis: “This isn’t Amsterdam.” Minneapolis parents: “So what? We’ll make our own version.”
Photo shows  a family of three riding bikes on a protected bike lane. One parent is riding an electric cargo trike with a kids bike attached to the back. The other parent is riding beside them on an electric bike. Two parents and three kids ride bikes on a protected bike lane. The two older kids are riding their own bikes and the youngest is riding behind one of the parents on an electric bike. 
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Gravel Influencer @gravelinfluencer.bsky.social · 01/08/2026
Car brained leaders and NIMBYs like to portray bike and safe streets advocates as some tiny group of extremist elites and videos like this are a good reminder of just how many of us are out there fighting for our lives.
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Nicolas Fernandez @cornhundred.bsky.social · 01/08/2026
Check out this proof-of-concept website built with Claude that walks through an example multimodal live-cell imaging and Cell Painting workflow from Darian Ventura's (bit.ly/4534nBr) cell motility work cornhundred.github.io/cell_motilit... #celldega #Jupyter #anywidget #CellPainting #cellpose
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Gravel Influencer @gravelinfluencer.bsky.social · 15/07/2026
Someone tried to insult me by saying I'm "stanning for e-bikes" and yeah buddy, I am wholeheartedly championing a revolutionary form of transportation that is making biking more accessible and enabling people to drive their cars less
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Hoodlum 🇺🇸 @nothoodlum.bsky.social · 15/07/2026
She can duck and weave, but Susan Collins is the chair of the Senate Appropriations Committee. She’s responsible for overseeing the appropriations process, including funding for ICE. Collins voted in favor of providing $70 billion in additional funding for ICE and Border Patrol. Vote her out.
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Aaron Rupar @atrupar.com · 11/07/2026
This is total insanity. Words fail to explain how anyone let alone a plurality of voters thought giving an obviously demented person control of the most powerful government in the world was a good idea. We will be lucky to come out the other side of this alive.
1000 Missiles are Locked and Loaded and aimed at the Islamic Republic of Iran, with thousands of more to immediately follow, should the Iranian Government act on its threat, pronounced in many corners of the Globe, to assassinate, or attempt to assassinate, the sitting President of the United States of America, in this case, ME! Orders have already been given, and the U.S. Military is ready, willing, and able, for a one year period of time, subject to extension, to completely decimate and destroy all areas of Iran - PRAISE BE TO ALLAH! President DONALD J. TRUMP
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Gravel Influencer @gravelinfluencer.bsky.social · 09/07/2026
Every cyclist death is heartbreaking, but it hits even harder when it's an advocate like this. It's infuriating and saddening. These deaths, especially on roads that are known to be dangerous, are simply policy choices.
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Thomas Bamonte @thomasbamonte.bsky.social · 09/07/2026
The takeaway for cities: “The best bang for your buck is protected bike lanes,” Moran told Bike Talk‘s Nick Richert. “Really focus on bike infrastructure that’s protected. That’s how you grow ridership. That’s how you diversify ridership.” sf.streetsblog.org/2026/07/08/s...
sf.streetsblog.org
Study: Only Protected Bike Lanes Cause a Real Increase in Cycling - Streetsblog San Francisco
"The best bang for your buck is protected bike lanes... That's how you grow ridership. That's how you diversify ridership."
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J¡m Vaughn @jiminyspigot.bsky.social · 10/07/2026
I, for one, welcome our new gay baseball overlords.
them.us
The Women’s Pro Baseball League Is Here — And It’s Even Gayer Than the WNBA
​The WPBL shared the names and jerseys of its first four teams in Boston, Los Angeles, New York, and San Francisco.
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Brent Toderian @brenttoderian.bsky.social · 10/07/2026
Never forget, a 13-year study found that protected bike-lanes led to a drastic decline in fatalities for all road users. ALL ROAD USERS. What about painted bike-lanes? No safety improvement at all. For sharrows, it’s actually safer to NOT have them. Via @usa.streetsblog.org @nyc.streetsblog.org
usa.streetsblog.org
Separated Bike Lanes Means Safer Streets, Study Says — Streetsblog USA
Cities that build protected lanes for cyclists end up with safer roads for people on bikes and people in cars and on foot, a new study of 12 large metropolises revealed Wednesday.
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Brent Toderian @brenttoderian.bsky.social · 02/07/2026
“The city’s transition away from the car, tho fantastically chaotic, has become a global role model. Under mayor @annehidalgo.bsky.social, Paris was ‘the most influential city in the world’ says Canadian urbanist Brent Toderian. Hidalgo, stepping down after 12 yrs, exulted: ‘The bike beat the car.’”
ft.com
How Paris beat the car
Though chaotic, the city’s transition has become a global role model
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Darren Buck @bikepedantic.bsky.social · 28/06/2026
A cargobike couldn’t substitute for the station wagon for the Goodwill dropoff. TWO cargobikes however…
A cargobike with boxes loaded on it in foreground, cargobike loaded in background
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derek guy @dieworkwear.bsky.social · 27/06/2026
To answer everyone's question: Yes, this is bad for the suit, as water can shrink the different layers inside at different rates (face cloth, haircloth, canvas, and padding). If this happens, the damage can't be reversed. That said, I admire his commitment to wearing a suit at all times.
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Nicolas Fernandez @cornhundred.bsky.social · 27/06/2026
Turkey crossing the bike lane and road 🦃 🚲 #cambridge @cambbikesafety.bsky.social @cambridgemass.bsky.social
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Fietser Brandon @americanfietser.bsky.social · 25/06/2026
​I grew up farming and hold a CDL. I genuinely love semis, heavy machinery, big jets, and rural life. I’m ALSO a bikes-for-transportation advocate, urban infrastructure nerd, and "ban cars" enjoyer. ​I don't normally mix my interests here on Fietser, because...
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Tom Flood @tomflood.bsky.social · 21/06/2026
Pro Tip: Go to every event, extra curricular, school trip you can, do whatever it takes to make that happen. Tuck them in even though you’re tired, play with with them even though you’re busy, hug them even though you’re mad as hell. talk to them even if you’re spent - it goes by so goddamn fast.
me standing with my kid when they were young at a school father's day party
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The War on Cars @thewaroncars.bsky.social · 20/06/2026
"The glee with which Superman carries out his obliteration of the vehicles and the terror of the bystanders is palpable. It all feels like revenge for something." This story features prominently in our book, LIFE AFTER CARS. Superman, welcome to The War on Cars!
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Dude @impenetrable.bsky.social · 20/06/2026
About right 🤣
#TheITGrowd
HOORAY. HE'S KICKED THE BALL, NOW THE BALL'S OVER THERE. THAT MAN HAS IT NOW.
THAT'S AN INTERESTING DEVELOPMENT.
MAYBE HE'LL KICK THE BALL. HE HAS INDEED AND APPARENTLY THAT DESERVES A ROUND OF APPLAUSE.
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Chico Escuela @blaqdocdown.bsky.social · 20/06/2026
New York Knicks with Zohran Mamdani in City Hall after their NBA Championship parade. Photographed by Ali Imam.
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Nick Langley @nicklangley.bsky.social · 20/06/2026
#SUVs: The psychopath's choice. “Buying whatever vehicle we like, and driving it wherever and whenever we please without having to think about the consequences for other people, has become normalised and ingrained across our society over decades." www.theguardian.com/world/2026/j...
theguardian.com
SUV buyers undeterred by warnings of risk to pedestrians, UK study finds
Exclusive: Research suggests financial penalties necessary if number of large vehicles on roads is to be reduced
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Leah Hyman @lmdawkins.bsky.social · 20/06/2026
There are so many things I love about my town, and our bike traffic signage is definitely one of them. Portland, OR.
3 traffic signs on a pole that say, in order:
Bicycles may use full lane
Neighborhood Greenway
Bike Bus, with a cute illustration of a big person on a bike followed by 4 small people on bikes.
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Philip Bump @pbump.com · 19/06/2026
I’m sorry, no. This is not the guy who did the reflecting pool. No. Come on. We’re just putting a hat on a hat here. www.nytimes.com/2026/06/18/u...
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The War on Cars @thewaroncars.bsky.social · 18/06/2026
Timothee Chalamet and Kylie Jenner, welcome to The War on Cars.
people.com
Timothée Chalamet and Kylie Jenner Spotted Biking Around N.Y.C. Day Before Knicks Victory Parade
Timothée Chalamet and Kylie Jenner may be getting ready for the Knicks victory parade, after they were spotted together biking and walking around New York City on Wednesday, June 17.
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The War on Cars @thewaroncars.bsky.social · 17/06/2026
We are once again asking Mayor Mamdani... @mayor.nyc.gov
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Darren Buck @bikepedantic.bsky.social · 16/06/2026
First in a series: Drivers of Cambridge doing their best and failing to stop at the stop sign immediately next to the playground.
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Nicolas Fernandez @cornhundred.bsky.social · 16/06/2026
Welcome to the war on cars Boston @thewaroncars.bsky.social - spotted on way to the @humancellatlas.org #HCA2026GM #boston
The Boston Cotgo sign is shown partially disassembled and a see through triangle.
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Juliet Shen @julietshen.online · 09/06/2026
this is the way
a crowd of people sit in folding chairs and stand around a TV showing the Knicks game outside a deli in nyc
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Tom Flood @tomflood.bsky.social · 08/06/2026
A message for the masses.
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Amanda Mull @amandamull.bsky.social · 08/06/2026
Thought you guys might enjoy this enormous cat who manages a butcher shop
A fluffy gray Norwegian forest cat—who is, I cannot emphasize enough, enormous—sits in front of a butcher shop display case and a rack of flavored potato chips. He has so many toes.
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Jason Concepcion @netw3rk.bsky.social · 06/06/2026
Peter Thiel fleeing to Argentina ahh interesting. Grok, has anyone else fled to Argentina in years past?
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Willie Lopez @willielopezshow.bsky.social · 06/06/2026
As the Son of a Dad who owned bodegas for over a decade in the Bronx growing up, I can relate. IT'S AN AWESOME NICKNAME! I did not realize that Bodega Kat is actually part Dominican as his Mom was from the Domican Republic! He obviously has frequented many a "bodega" growing up in Jersey! #BodegaKAT
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Real Ale Cyclist @realalecyclist.bsky.social · 06/06/2026
Test ride of a Brompton electric G line. First time on an e-bike. Massive fun on it, throughly enjoyed myself. Even did 2 ascents of the killer hill to test how the motor works best. Think I'll be getting one as my train/pub bike for trips out further afield.
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Willie Lopez @willielopezshow.bsky.social · 06/06/2026
I can't say enough about the player that Karl Athony Towns, affectionately known as "Bodega KAT", is! The only thing better than his balls skills is the MAN that he is! His upbringing & the passing of his Mom has had a profound impact on his life. He is so well spoken & thankful. God bless you! 🙏✝️
static.klipy.com
Karl-Anthony Towns Knicks Celebration
ALT: Karl-Anthony Towns Knicks Celebration
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CJ Fogler @cjzero.bsky.social · 06/06/2026
Jeremy Lin's jacket liner has images of Linsanity headlines & magazine covers
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The War on Cars @thewaroncars.bsky.social · 06/06/2026
just sayin'
satellite image of frost bank center in san antonio showing arena with parking on two sides.satellite image of madison square garden showing msg in middle of manhattan street grid.
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Gravel Influencer @gravelinfluencer.bsky.social · 04/06/2026
A Boston bike commuter posted a video on reddit of nearly being killed by a speeding pick-up truck driver racing to a red light. Something non-cyclists probably don't realize is that it's not uncommon for riders to have multiple encounters like this on a ride. Source: www.reddit.com/r/bikecommut...
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The War on Cars @thewaroncars.bsky.social · 04/06/2026
Knicks fans, welcome to The War on Cars.
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Dr. Lucky Tran @luckytran.com · 01/06/2026
BREAKING: Mayor Mamdani just signed an “executive order” to repeal bedtime so NYC kids can watch the Knicks play in the NBA Finals!
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