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Alberto Sanz

@albertosanzmon1.bsky.social
80 followers 66 following 30 posts

A scientist researching aging. Passionate about unlocking all forms of knowledge. Championing technology as a catalyst for human progress.

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Alberto Sanz @albertosanzmon1.bsky.social · 27/06/2026
Latest publication from Mario Cordero's lab: NLRP3 haploinsufficiency unmasks a compensatory NLRP1-NLRP3 interaction that drives accelerated aging in mice | Science Advances www.science.org/doi/10.1126/... with a modest contribution from yours truly ;-)
science.org
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Reposted by Alberto Sanz
Korolchuk Lab @korolchuklab.bsky.social · 26/04/2026
My son is raising money for @msf.ca. Please help by donating and spreading the word 🙏🏻 www.justgiving.com/page/ivan-ko...
justgiving.com
100km Ultramarathon for Medical Care in Crisis Zones
Help Ivan Korolchuk raise money to support Medecins Sans Frontieres / Doctors Without Borders (MSF)
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Reposted by Alberto Sanz
Mike Murphy @mitoredox.bsky.social · 30/01/2026
Funding? I'm a simple academic, so I'll have to await someone smart to explain to me how "pausing" MRC and BBSRC funding is the action of a biomedical science superpower...?
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Michael Rera @michaelrera.bsky.social · 24/12/2025
😂 and this is after a full round of review at Nature... read the paper anyway, it's still good :) www.biorxiv.org/content/10.1...
biorxiv.org
Proteome-wide Prediction of the Functional Impact of Missense Variants with ProteoCast
Background Dissecting the functional impact of genetic mutations is essential to advancing our understanding of genotype-phenotype relationships and identifying new therapeutic targets. Despite the pr...
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Reposted by Alberto Sanz
Anthony Dornan @dornan.bsky.social · 23/12/2025
A welcome finish to what has been, & continues to be, a rough year. Proud to have been a (small) part of this work published in @elife.bsky.social, which, as always from the Dobson Lab, is meticulous, thorough & insightful.
doi.org
Microbiota impact Drosophila ageing via Acetobacter, Tachykinin, and TkR99D
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Alberto Sanz @albertosanzmon1.bsky.social · 17/12/2025
PhD studentship at @glasgow.ac.uk #Mitochondria × #spectroscopy × #machinelearning. Detect mitochondrial defects, estimate age, and identify anti-ageing drugs across species. Supervisors: @albertosanzmon1.bsky.social @mariogonzalez.es & @nealdawson.bsky.social UK Home fees only. shorturl.at/wvMQa
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Reposted by Alberto Sanz
Mike Murphy @mitoredox.bsky.social · 15/12/2025
Huge congratulations to Abigail Giles whose paper has just come out in Nature Cardiovascular Research - from a great collaboration with Bob Balaban, along with Thomas Krieg and Tish Murphy. doi.org/10.1038/s441...
doi.org
Rapid mitochondrial repolarization upon reperfusion after cardiac ischemia - Nature Cardiovascular Research
Giles et al. developed a method for noninvasive absorbance measurement of mitochondrial hemes to monitor the mitochondrial membrane potential in the perfused heart. They then applied this approach to ...
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Alberto Sanz @albertosanzmon1.bsky.social · 07/12/2025
We have updated a previous preprint from our laboratory, and after two additional years of experiments, we now present new findings that fundamentally reshape how we—meaning us, not necessarily everyone—understand ageing. www.biorxiv.org/content/10.1...
biorxiv.org
Developmental Programming of Mitochondrial Function Limits Lifespan in Short-Lived Animals
The contribution of mitochondria to lifespan determination remains controversial, as impaired mitochondrial function can paradoxically both shorten and extend longevity. During ageing, mitochondria ac...
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Alberto Sanz @albertosanzmon1.bsky.social · 07/12/2025
We have updated a previous preprint from our laboratory, and after two additional years of experiments, we now present new findings that fundamentally reshape how we—meaning us, not necessarily everyone—understand ageing. www.biorxiv.org/content/10.1...
biorxiv.org
Developmental Programming of Mitochondrial Function Limits Lifespan in Short-Lived Animals
The contribution of mitochondria to lifespan determination remains controversial, as impaired mitochondrial function can paradoxically both shorten and extend longevity. During ageing, mitochondria ac...
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Alberto Sanz @albertosanzmon1.bsky.social · 31/10/2025
Two weeks left to apply for a PhD position in my laboratory at #Glasgow. The project focuses on #Ageing, #Mitochondria, and #Drosophila, with emphasis on Complex I (CI) function. Fees are fully covered for applicants eligible for UK Home Student status. www.findaphd.com/phds/project...
findaphd.com
FULLY FUNDED PhD - Identifying Critical Periods for Mitochondrial Function in Drosophila Development and Lifespan at University of Glasgow on FindAPhD.com
PhD Project - FULLY FUNDED PhD - Identifying Critical Periods for Mitochondrial Function in Drosophila Development and Lifespan at University of Glasgow, listed on FindAPhD.com
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Alberto Sanz @albertosanzmon1.bsky.social · 17/10/2025
There is a PhD Studentship in my laboratory starting in March 2026. Please contact me if you are interested. www.findaphd.com/phds/project...
findaphd.com
FULLY FUNDED PhD - Identifying Critical Periods for Mitochondrial Function in Drosophila Development and Lifespan at University of Glasgow on FindAPhD.com
PhD Project - FULLY FUNDED PhD - Identifying Critical Periods for Mitochondrial Function in Drosophila Development and Lifespan at University of Glasgow, listed on FindAPhD.com
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Alberto Sanz @albertosanzmon1.bsky.social · 23/06/2025
ROS Signalling, not ROS Damage: A new Paradigm in Ageing youtu.be/yt1kiuOyNtY?... via @YouTube #Aging #ROS #Drosophila #Mitochondria
youtu.be
ROS Signalling, not ROS Damage: A new Paradigm in Ageing
YouTube video by The Sanz Science Experience
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Alessandro Prigione @aleprigio.bsky.social · 19/05/2025
Exciting news! Our most important work is out as preprint! We suggest sildenafil as a treatment for mitochondrial disease Leigh syndrome, from stem and organoid model to mice and off-label use. Next step is the clinical trial starting early next year! www.medrxiv.org/content/10.1...
medrxiv.org
Pluripotent stem cell-based drug discovery uncovers sildenafil as a treatment for mitochondrial disease
Mitochondrial disease encompasses inherited disorders affecting mitochondrial function. A severe and untreatable form of mitochondrial disease is Leigh syndrome (LS) causing psychomotor regression and...
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Alberto Sanz @albertosanzmon1.bsky.social · 02/05/2025
NAD+ Boosters: Slowing Aging or Selling Hype? youtu.be/0QxzAz9B--Y?... via @YouTube #aging #healthyaging #NAD+ #NADH #muscle #supplements #hype
youtu.be
NAD+ Boosters: Slowing Aging or Selling Hype?
YouTube video by Science Sanz Hub
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Alberto Sanz @albertosanzmon1.bsky.social · 08/05/2025
What's Aging? A Survey Among Professionals youtu.be/iX_QUwrHkfY?... via @YouTube #aging #surve #disagreement
youtu.be
What's Aging? A Survey Among Professionals
YouTube video by Science Sanz Hub
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Alberto Sanz @albertosanzmon1.bsky.social · 02/05/2025
NAD+ Boosters: Slowing Aging or Selling Hype? youtu.be/0QxzAz9B--Y?... via @YouTube #aging #healthyaging #NAD+ #NADH #muscle #supplements #hype
youtu.be
NAD+ Boosters: Slowing Aging or Selling Hype?
YouTube video by Science Sanz Hub
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Alberto Sanz @albertosanzmon1.bsky.social · 20/04/2025
Age Deceleration and Reversal in C elegans youtu.be/QSmpKDEjYNA?... #aging #worms #celegans #dauer
youtu.be
Age Deceleration and Reversal in C elegans
YouTube video by Science Sanz Hub
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Alberto Sanz @albertosanzmon1.bsky.social · 17/04/2025
How does a Fly Die? And why should we care? #Drosophila #Aging #Biology youtu.be/-akcyD68-eA?...
youtu.be
How Does a Fly Die? And why should we care?
YouTube video by Science Sanz Hub
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Alberto Sanz @albertosanzmon1.bsky.social · 15/04/2025
A concise and excellent summary of our recent @emboreports.org manuscript, now published in @natsmb.nature.com. www.nature.com/articles/s41...
nature.com
Timing of complex I activity and lifespan control - Nature Structural & Molecular Biology
Nature Structural & Molecular Biology - Timing of complex I activity and lifespan control
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Alberto Sanz @albertosanzmon1.bsky.social · 23/03/2025
New paper from my laboratory in EMBO Reports doi.org/10.1038/s443.... Our study challenges what we know about #mitochondria & #aging.
embopress.org
Developmental mitochondrial complex I activity determines lifespan | EMBO reports
imageimageTemporal manipulation of CI function reveals development as critical window where reduction of CI produces short-lived and stress sensitive adults characterised by maladaptive transcriptomic...
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Alberto Sanz @albertosanzmon1.bsky.social · 23/03/2025
A podcast discussing our paper on the role of CI on aging and mitochondrial disease: www.youtube.com/watch?v=Usu7...
youtube.com
Timing Mitochondrial Dysfunction: The Key to Regulating Aging
YouTube video by Science Sanz Hub
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Alberto Sanz @albertosanzmon1.bsky.social · 23/03/2025
New paper from my laboratory in EMBO Reports doi.org/10.1038/s443.... Our study challenges what we know about #mitochondria & #aging.
embopress.org
Developmental mitochondrial complex I activity determines lifespan | EMBO reports
imageimageTemporal manipulation of CI function reveals development as critical window where reduction of CI produces short-lived and stress sensitive adults characterised by maladaptive transcriptomic...
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