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GerstnerLab

@gerstnerlab.bsky.social
367 followers 119 following 23 posts

The Laboratory of Computational Neuroscience @EPFL studies models of neurons, networks of neurons, synaptic plasticity, and learning in the brain.

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Alireza Modirshanechi @modirshanechi.bsky.social · 15/08/2026
Excited to share that I'll be starting as a junior professor and Emmy Noether awardee at the University of Göttingen this October! 🥳 🚀 I'll be hiring #phd students and #postdoc across #machinelearning, #neuroscience and #cogsci: modirlab.github.io/open-positio... Please spread the word! 🙏
PhD ad informationPostdoc ad informationInformation about Göttingen and equal opportunities
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Shuqi Wang @shuqiw.bsky.social · 15/07/2026
Our paper "Rarely categorical, highly separable representations along the cortical hierarchy" is now out in Nature! www.nature.com/articles/s41... In this paper, we studied whether the brain is well-organized and interpretable, both globally and locally. (See thread below.)
nature.com
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Louis Pezon @lpezon.bsky.social · 30/06/2026
Both brains and RNNs can re-use components of computation across similar tasks or contexts. But what exactly are those “shared components”? How can they be used to solve several tasks? We address these questions in a new preprint with @avm.bsky.social! Link: www.biorxiv.org/content/10.6...
biorxiv.org
Interpretable compositional computation with recurrent neural networks
Flexible cognition utilizes reusable components to enable rapid adaptation of behavior to different contexts or tasks. Analysis of artificial neural networks trained on multiple tasks suggested that t...
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GerstnerLab @gerstnerlab.bsky.social · 29/06/2026
How can the brain learn the hidden hierarchical structure from high dimensional data? In our latest work, we use synthetic datasets to analyze two classes of bio-plausible learning rules: variants of Direct Feedback Alignment, and local self-supervised learning. We find only the latter succeeds.
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GerstnerLab @gerstnerlab.bsky.social · 22/06/2026
📂 We're sharing code of a classic from the lab! A biologically inspired RL model from Frémaux, Sprekeler @sprekeler.bsky.social & Gerstner (2013, PLOS CB): a continuous-time actor–critic using spiking neurons that learn to navigate a water maze
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Guillaume Bellec @bellecguill.bsky.social · 17/06/2026
Accepted at ICML 2026. I am extremely proud of this work. Local learning is starting to work really well! The theoretical perspective of local learning minimizing an emergent global objective has been eye opening Congrats @zihan-wu.bsky.social and Ariane Delrocq! Great team
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GerstnerLab @gerstnerlab.bsky.social · 16/06/2026
How far are biologically-plausible local learning rules from backpropagation (BP)? In our new ICML paper we look at local self-supervised learning and find how to better align its gradients to BP. We achieve competitive performance on various datasets!
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GerstnerLab @gerstnerlab.bsky.social · 10/06/2026
Ever heard of the lottery ticket hypothesis? Our new paper shows that lottery tickets are not a useful metaphor to explain the success of overparameterized neural networks - and suggests an alternative metaphor: escape dimensions
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Sophia Becker @sobeckerneuro.bsky.social · 27/05/2026
Incredibly grateful to @cmiehl.bsky.social and @gjorjulijana.bsky.social for their thoughtful and spot-on Preview "Novelty beyond counting" of our recent work in Neuron with @modirshanechi.bsky.social and @gerstnerlab.bsky.social! 🧠✨ It's a real honor 🙏 www.cell.com/neuron/fullt...
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Valentin Schmutz @bio-emergent.bsky.social · 08/05/2026
Unbelievably honoured to read Tatiana Engel's (@engeltatiana.bsky.social) wonderfully written Preview on our work "Linking neural manifolds to circtuit structure in recurrent networks" (with @lpezon.bsky.social & @gerstnerlab.bsky.social) in this issue of Neuron www.cell.com/neuron/fullt... 🙏
cell.com
Finding clues to circuit structure in population dynamics and single-neuron selectivity
In this issue of Neuron, Pezon et al. introduce neural circuit models with flexible connectivity structure that can generate low-dimensional population dynamics with different distributions of single-...
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Gaute Einevoll @gauteeinevoll.bsky.social · 28/03/2026
Episode #39 in #TheoreticalNeurosciencePodcast: On modeling neural population activity with mean-field models – with Tilo Schwalger theoreticalneuroscience.no/thn39 How can mean‑field models be systematically derived from the underlying microscopic dynamics of individual neurons?
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EPFL Brain Mind Institute @epfl-brainmind.bsky.social · 01/04/2026
Novelty is not just about whats new, but also what feels new given past experience. New study from Sophia Becker in Wulfram Gerstner’s @epfl-brainmind.bsky.social lab posits a model showing how similarity between familiar and novel stimuli shapes exploration and learning - doi.org/10.1016/j.ne...
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Louis Pezon @lpezon.bsky.social · 13/03/2026
Presenting a poster tomorrow at Cosyne 26: [3-033] Compositional computation via shared latent dynamics in low-rank RNNs. With @avm.bsky.social, we explore how RNNs can re-use the same dynamics across different tasks, and what it implies for their connectivity and neural activity.
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Louis Pezon @lpezon.bsky.social · 06/03/2026
Excited to share our new paper to be published in Neuron! With Valentin Schmutz @bio-emergent.bsky.social and Wulfram Gerstner @gerstnerlab.bsky.social, we explore how circuit structure in RNNs shapes network computation and single-neuron responses. www.sciencedirect.com/science/arti...
sciencedirect.com
Linking neural manifolds to circuit structure in recurrent networks
Dimensionality reduction methods are widely used in neuroscience to investigate two complementary aspects of neural activity: the distribution of sing…
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Flavio Martinelli @flavioh.bsky.social · 04/12/2025
🧵Excited to present our latest work at #Neurips25! Together with @avm.bsky.social, we discover 𝐜𝐡𝐚𝐧𝐧𝐞𝐥𝐬 𝐭𝐨 𝐢𝐧𝐟𝐢𝐧𝐢𝐭𝐲: regions in neural networks loss landscapes where parameters diverge to infinity (in regression settings!) We find that MLPs in these channels can take derivatives and compute GLUs 🤯
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Alexander van Meegen @avm.bsky.social · 05/11/2025
This was a lot of fun! From my side, it started with a technical Q: what's the relation between two-side cavity and path integrals? Turns out it's a fluctuation correction - and amazingly, this also enable the "O(N) rank" theory by @david-g-clark.bsky.social and @omarschall.bsky.social. 🤯
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GerstnerLab @gerstnerlab.bsky.social · 30/09/2025
Lab members are at the Bernstein conference @bernsteinneuro.bsky.social with 9 posters! Here’s the list: TUESDAY 16:30 – 18:00 P1 62 “Measuring and controlling solution degeneracy across task-trained recurrent neural networks” by @flavioh.bsky.social
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Alireza Modirshanechi @modirshanechi.bsky.social · 28/09/2025
New in @pnas.org: doi.org/10.1073/pnas... We study how humans explore a 61-state environment with a stochastic region that mimics a “noisy-TV.” Results: Participants keep exploring the stochastic part even when it’s unhelpful, and novelty-seeking best explains this behavior. #cogsci #neuroskyence
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Valentin Schmutz @bio-emergent.bsky.social · 19/09/2025
🎉 "High-dimensional neuronal activity from low-dimensional latent dynamics: a solvable model" will be presented as an oral at #NeurIPS2025 🎉 Feeling very grateful that reviewers and chairs appreciated concise mathematical explanations, in this age of big models. www.biorxiv.org/content/10.1... 1/2
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GerstnerLab @gerstnerlab.bsky.social · 04/09/2025
🧠 “You never forget how to ride a bike”, but how is that possible? Our study proposes a bio-plausible meta-plasticity rule that shapes synapses over time, enabling selective recall based on context
sciencedirect.com
Context selectivity with dynamic availability enables lifelong continual learning
“You never forget how to ride a bike”, – but how is that possible? The brain is able to learn complex skills, stop the practice for years, learn other…
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Alireza Modirshanechi @modirshanechi.bsky.social · 25/08/2025
So happy to see this work out! 🥳 Huge thanks to our two amazing reviewers who pushed us to make the paper much stronger. A truly joyful collaboration with @lucasgruaz.bsky.social, @sobeckerneuro.bsky.social, and Johanni Brea! 🥰 Tweeprint on an earlier version: bsky.app/profile/modi... 🧠🧪👩‍🔬
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Alireza Modirshanechi @modirshanechi.bsky.social · 13/08/2025
Attending #CCN2025? Come by our poster in the afternoon (4th floor, Poster 72) to talk about the sense of control, empowerment, and agency. 🧠🤖 We propose a unifying formulation of the sense of control and use it to empirically characterize the human subjective sense of control. 🧑‍🔬🧪🔬
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GerstnerLab @gerstnerlab.bsky.social · 08/08/2025
Is it possible to go from spikes to rates without averaging? We show how to exactly map recurrent spiking networks into recurrent rate networks, with the same number of neurons. No temporal or spatial averaging needed! Presented at Gatsby Neural Dynamics Workshop, London.
youtu.be
From Spikes To Rates
YouTube video by Gerstner Lab
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Lucas Gruaz @lucasgruaz.bsky.social · 11/06/2025
Excited to present at the PIMBAA workshop at #RLDM2025 tomorrow! We study curiosity using intrinsically motivated RL agents and developed an algorithm to generate diverse, targeted environments for comparing curiosity drives. Preprint (accepted but not yet published): osf.io/preprints/ps...
osf.io
OSF
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Sophia Becker @sobeckerneuro.bsky.social · 11/06/2025
Stoked to be at RLDM! Curious how novelty and exploration are impacted by generalization across similar stimuli? Then don't miss my flash talk in the PIMBAA workshop (tmr at 10:30, E McNabb Theatre) or stop by my poster tmr (#74)! Looking forward to chat 🤩 www.biorxiv.org/content/10.1...
biorxiv.org
Representational similarity modulates neural and behavioral signatures of novelty
Novelty signals in the brain modulate learning and drive exploratory behaviors in humans and animals. While the perceived novelty of a stimulus is known to depend on previous experience, the effect of...
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Valentin Schmutz @bio-emergent.bsky.social · 09/06/2025
Our new preprint 👀
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Alexander van Meegen @avm.bsky.social · 10/06/2025
Interested in high-dim chaotic networks? Ever wondered about the structure of their state space? @jakobstubenrauch.bsky.social has answers - from a separation of fixed points and dynamics onto distinct shells to a shared lower-dim manifold and linear prediction of dynamics.
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Gaute Einevoll @gauteeinevoll.bsky.social · 07/12/2024
Episode #22 in #TheoreticalNeurosciencePodcast: On 50 years with the Hopfield network model - with Wulfram Gerstner theoreticalneuroscience.no/thn22 John Hopfield received the 2024 Physics Nobel prize for his model published in 1982. What is the model all about? @icepfl.bsky.social
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Valentin Schmutz @bio-emergent.bsky.social · 22/01/2025
A cool EPFL News article was written about our recent neurotheory paper on spikes vs rates! Super engaging text by science communicater Nik Papageorgiou. actu.epfl.ch/news/brain-m... Definitely more accessible than the original physics-style, 4.5-page letter 🤓 journals.aps.org/prl/abstract...
actu.epfl.ch
Brain models draw closer to real-life neurons
Researchers at EPFL have shown how rough, biological spiking neural networks can mimic the behavior of brain models called recurrent neural networks. The findings challenge traditional assumptions and...
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Alireza Modirshanechi @modirshanechi.bsky.social · 10/01/2025
Super excited to see my PhD thesis featured by EPFL! 🎓 actu.epfl.ch/news/learnin... P.S.: There's even a French version of the article! It feels so fancy! 😎 👨‍🎨 🇫🇷 actu.epfl.ch/news/apprend...
actu.epfl.ch
Learning from the unexpected
A researcher at EPFL working at the crossroads of neuroscience and computational science has developed an algorithm that can predict how surprise and novelty affect behavior.
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Valentin Schmutz @bio-emergent.bsky.social · 06/01/2025
New round of spike vs rate? The concentration of measure phenomenon can explain the emergence of rate-based dynamics in networks of spiking neurons, even when no two neurons are the same. This is what's shown in the last paper of my PhD, out today in Physical Review Letters 🎉 tinyurl.com/4rprwrw5
tinyurl.com
Emergent Rate-Based Dynamics in Duplicate-Free Populations of Spiking Neurons
Can spiking neural networks (SNNs) approximate the dynamics of recurrent neural networks? Arguments in classical mean-field theory based on laws of large numbers provide a positive answer when each ne...
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Guillaume Bellec @bellecguill.bsky.social · 08/01/2025
Pre-print 🧠🧪 Is mechanism modeling dead in the AI era? ML models trained to predict neural activity fail to generalize to unseen opto perturbations. But mechanism modeling can solve that. We say "perturbation testing" is the right way to evaluate mechanisms in data-constrained models 1/8
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