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Carlos Rodríguez

@carloslab.bsky.social
614 followers 1.5K following 46 posts

#newPI studying plant chemical diversity through Mass Spectrometry, and Natural Products biosynthesis whenever I can. Opinions are my own. 🇲🇽

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Reposted by Carlos Rodríguez
German Society for Plant Sciences (DBG) @plantsciencedbg.bsky.social · 10/07/2026
Microbial volatile compounds enhance drought resilience and productivity in CAM and C3 crops. Read more #OpenAccess in our Journal #PlantBiology @Wileyplantsci #PlantSci DOI: doi.org/10.1111/plb....
doi.org
Microbial volatile compounds enhance drought resilience and productivity in <fc>CAM</fc> and <fc>C3</fc> crops
Microbial volatiles EV and CAMP, derived from Bacillus spp. and Beauveria pseudobassiana associated with agaves and cacti, respectively, enhance drought resilience and productivity in Agave tequilana...
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Reposted by Carlos Rodríguez
Dr. Adeene Denton @spacewhalerider.com · 11/05/2026
"Scientists don't want you to know-" Buddy there are so many things I, as a scientist, want you to know and the only thing stopping me from writing more papers and posts about it and then starting a podcast to tell you even MORE things is that I am limited by hours in the day
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Lichman Lab @lichmanlab.bsky.social · 18/05/2026
Pleased to share our full publication of our manuscript describing completion of nicotine biosynthesis in @natcomms.nature.com following our pre-print from December last year. In this work we solve the 200-year-old puzzle of how tobacco plants make nicotine. www.nature.com/articles/s41...
nature.com
Nicotine biosynthesis is completed by cryptic activating glucosylation - Nature Communications
Despite the significance of nicotine, a neuroactive alkaloid produced by tobacco, its biosynthesis has remained elusive. Here, the authors report the in vitro and in planta&nbsp;reconstruction of a fo...
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Maite Colinas @maitecolinas.bsky.social · 10/02/2026
In our latest preprint we report the unexpected discovery of Epi-STR, an R-stereoselective ortholog of the S-selective canonical Strictosidine synthases (STRs). Found in the rather obscure plant Pogonopus specious. This work was led by my stellar student Clara Morweiser! #natprod #PlantScience
Scheme showing the Pictet-Spengler reaction between tryptamine and a secoiridoid by canonical S-selective STRs compared to the newly discovered Epi-STR. On the right a photo of the pink flowers of Pogonopus speciosus. Photo taken by Eva Rothe.
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Maite Colinas @maitecolinas.bsky.social · 11/04/2026
Our funky R-stereoselective Epi-STR is now available online and open access at its permanent home @angewandtechemie.bsky.social. 🥳 This is Clara's first first-author paper, makes me extra happy! @mpi-ce.bsky.social #PlantScience #natprod doi.org/10.1002/anie...
A collage showing on the left a picture of the  bright pink closed flowers and bracts of the plant Pogonopus speciosus. On the right a scheme depicting the reaction of tryptamine and secologanic acid to vincosidic acid that is catalyzed by P. speciosus Epi-STR, an unusual R-stereoselective ortholog of strictosidine synthase.
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Philipp Bayer @philippbayer.bsky.social · 30/03/2026
I'm glad I'm not in this sector any more. Working seven days, having to fight for every cent, receiving zero support, and then they turn around and spend billions on their mates. Why should I (or anyone) burn myself out for that www.abc.net.au/news/2026-03...
abc.net.au
As universities cut courses, spending on consultants and contractors nears $2b
Consultancies have been accused of infiltrating universities and wasting scarce public funds on questionable advice about cutting courses and jobs.
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Carlos Rodríguez @carloslab.bsky.social · 26/03/2026
I just got an e-mail asking me to "collaborate with data" that offers to put my name in a publication in exchange of experimentally testing some LLM-generated statement. I will not dignify that with an answer; my blood pressure can't deal with writing the appropriate answer.
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Shaily Patel @vox-magica.bsky.social · 23/03/2026
the upshot of all this is that universities shouldn't be chasing industry trends, or trends of any sort, probably. we cede our power to *set* intellectual and cultural trends when we do that. this power demands that we always remain a bit out-of-step. i'd give anything for us to see that.
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Chenxin Li, PhD @chenxinli2.bsky.social · 20/03/2026
I just had that conversation earlier this week. The college dean is deciding if they will (dis)continue the bioinformatics training program for grad students. An argument for discontinuation is that students will use GenAI to help them code, so they don’t need to learn bioinformatics.
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Chenxin Li, PhD @chenxinli2.bsky.social · 18/03/2026
Biosynthesis of cinchona alkaloids From: www.nature.com/articles/s41... #PlantScience #SpecMet
nature.com
Biosynthesis of cinchona alkaloids - Nature
A combination of isotopic labelling, gene silencing, single-nucleus RNA sequencing and comparative transcriptomics reveal the genes that mediate the biosynthesis of cinchona alkaloids in plants.
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Reposted by Carlos Rodríguez
Max Planck Institute for Chemical Ecology @mpi-ce.bsky.social · 18/03/2026
The process by which the cinchona tree produces quinine has been elucidated. In a new study published in @nature.com, researchers from the @oconnorlab.bsky.social and the @universityofga.bsky.social unveil the biosynthetic pathway behind this 400-year-old secret. www.ice.mpg.de/548102/PR_Ki...
ice.mpg.de
Mystery of quinine biosynthesis solved
For centuries, the process by which the cinchona tree produces its valuable alkaloids, including the life-saving quinine used to treat malaria, was shrouded in mystery. Now, a research team from the M...
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Michael D. Green, PhD @michaeldgreen.phd · 08/03/2026
I’ve seen ppl discuss how over 50% of their grants wouldn’t have been awarded @ current success rates. That’s an important reflection. What about the cost of living and the benefits you received at the start of your career? Expectations are higher, and many schools aren’t even offering startup $
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Reposted by Carlos Rodríguez
Nick Sousanis @nsousanis.bsky.social · 06/01/2026
In case anyone needs it for their syllabi, my statement in gen-Ai from the minicomic I made as a syllabus for class last semester. All online and printable here spinweaveandcut.com/fall-2025-sy...
a snippet of a mini-comic, at top - straight line stretches from point A to B. Immediately below, same dot at A, then becomes a curving, meandering line that winds through the page and ends at a point with rays and a question mark emanating from it. Text reads: "Nothing can do this for you - for that robs you of experience and conflates answers with learning. Rather, it's all the decisions you make along the way, the mistakes, struggles, and surprises! These pathways you create - this is learning. 

https://spinweaveandcut.com/fall-2025-syllabi/
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Henryk Straube @hstraube.bsky.social · 26/02/2026
🪴 🫘 🫛 Come work with us in beautiful Copenhagen! This is the erfect position for you, if you like: - natural products - working with plants - solving complex metabolism puzzles - having an applied impact shorturl.at/iIjW3
linkedin.com
Postdoc of Plant Natural Product Biosynthesis or Transport | Fernando Geu-Flores
🌿 Postdoc position in Plant Natural Products 🌿 📍 Geu-Flores lab at the University of Copenhagen (DK) 🥼 Are you passionate about uncovering how plants make and transport complex bioactive alkaloids? ...
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Carlos Rodríguez @carloslab.bsky.social · 25/02/2026
I forgot to ad hashtags!! #Biosynthesis #Olive #plantscience #NaturalProducts #SecMet I may have to repost this later this week; anyone know hashtags on natural product biosynthesis or enzyme/gene discovery?
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Carlos Rodríguez @carloslab.bsky.social · 25/02/2026
We're closing in on oleuropein biosynthesis in Olive! Oleuropein is the reason we can't eat raw olives, and also the "spicy" taste of olive oil. People assumed (and some wrongly reported) that the pathway was the same as in Catharanthus, but that's not entirely true! 🧵 www.cell.com/plant-commun...
cell.com
Comparative transcriptomic and co-expression analyses enable the discovery of key enzymes responsible for oleuropein biosynthesis in olive (Olea europaea)
Oleuropein, an oleoside-type secoiridoid, is the major determinant of olive oil flavor and quality. This study completes the biosynthetic pathway from 7-deoxy-loganic acid to 7-β-1-D-glucopyranosyl-ol...
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Nikolay Tumanov @ntumanovxray.bsky.social · 14/02/2026
You know, it would really add a bit credibility to your article if you would use correct structural formula of the (well-known) compound that you are studying. #chemsky www.mdpi.com/1999-4923/17...
A structural formula of "Lysine". Wrong one.
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Michael Hendricks 🇨🇦 @michaelhendricks.bsky.social · 23/01/2026
I like to tape these graphs next to the asbestos monitoring air pumps that have been running in my building since 2014.
A graph showing the increase of executive and management staff salaries at McGill (260%) since 2014-15 compared to full time faculty (125%). A second graph shows that academic salaries have decreased in real dollars by 4.2% while director/manager salaries have increased by 5.2%.
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New Phytologist @newphyt.bsky.social · 22/01/2026
In #Profile: Laila P. Partida-Martínez 👇 📖 nph.onlinelibrary.wiley.com/doi/10.1111/... #LatestIssue
Profile image of Laila P. Partida-Martínez
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Carlos Rodríguez @carloslab.bsky.social · 21/01/2026
There's something that breaks inside me whenever I read "human - AI collaboration" in a formal, scientific article. I don't collaborate with Excel or R anymore than I collaborare with a pipette or a mass spec. It's a marketing term that overstates capacities that editors should not allow.
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Carlos Rodríguez @carloslab.bsky.social · 16/01/2026
I need to start making my exams less dependent on NCBI; good thing it's 10mins to the end of the test, and that I also taught them to use the EBI. But there was some panic.
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Reposted by Carlos Rodríguez
Chenxin Li, PhD @chenxinli2.bsky.social · 18/12/2025
Our latest New Phytologist paper has been assigned an issue. #PlantScience #SecMet nph.onlinelibrary.wiley.com/doi/full/10.... Both papers advanced our understanding of how specialized metabolism are regulated in rare cell types to achieve cell type specificity. 1/n🧵
nph.onlinelibrary.wiley.com
A cell‐type‐specific regulon controlling monoterpene indole alkaloid biosynthesis with feedback and feedforward activation loops
Monoterpene indole alkaloids (MIA) are a diverse class of plant natural products produced by a subset of lineages within the Asterid clade of eudicots. The diversity of MIAs provides a unique opport.....
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Richard Sever @richardsever.bsky.social · 12/11/2025
The Matthew Effect is alive and well in academia - always makes me wary of programs aimed at identifying rising stars in an already highly talented pool... elifesciences.org/reviewed-pre...
elifesciences.org
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Mark A. Hanson @hansonmark.bsky.social · 11/11/2025
That's why funders hold the power here. Funders can decide to pay for services or not. They can decide to support authors who publish in for-profit journals, or not. They can decide to pay APCs in for-profit journals, or not. 9/n
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Elena Del Pup @elenadelpup.bsky.social · 29/10/2025
🌱plantiSMASH 2.0💥 is now live! I’m very excited to share that the 2.0 version of plantiSMASH is now available online and as a preprint on bioRxiv 📄https://lnkd.in/dN4F56pf 🌱 What’s new in plantiSMASH 2.0? ⬇️
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Carlos Rodríguez @carloslab.bsky.social · 16/09/2025
SAVE THE DATE! The annual meeting of the PSNA will be on June 15-19 in Wisconsin! Check the website go.wisc.edu/PSNA2026 and follow @psna-official.bsky.social for updates. And if you do research in phytochemistry, consider joining the PSNA; I've found the community to be very welcoming.
go.wisc.edu
PSNA2026@Madison
Save the date!! June 15 Monday - June 19 Friday, 2026
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Reposted by Carlos Rodríguez
Jeremy Baskin @jeremybaskin.bsky.social · 25/08/2025
Faculty opening in Cornell Chemistry at the Assistant Professor level in the area of chemical biology, broadly defined! academicjobsonline.org/ajo/jobs/30338 #chemjobs
academicjobsonline.org
Cornell University, Chemistry and Chemical Biology
Job #AJO30338, WDR-00054776 Assistant Professor - Chemistry and Chemical Biology, Cornell University (Ithaca, NY), Chemistry and Chemical Biology, Cornell University, Ithaca, New York, US
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Dr. Johnathan Flowers, Bisexual of the Blade (Alt-text or DIE) @shengokai.blacksky.app · 15/08/2025
Essentially, narratives about the efficiency and efficacy of AI have flooded our cultural conversation about AI thereby resulting in the uncritical uptake of anything branded as "AI" as inherently more valuable, more effective, than anything without AI, EVEN IF AI IS NOT NECESSARY.
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Carlos Rodríguez @carloslab.bsky.social · 14/08/2025
Has anyone else seen an increase in manuscript submissions using triple quads for untargeted metabolomics? Are vendors telling people they can do untargeted with a TQD? Or did I miss something?
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Swiss National Science Foundation (SNSF) @snsf.ch · 05/08/2025
Call for Ambizione Ambizione grants are aimed at early-career researchers who wish to conduct and lead a project of their own. Interested in learning more about this call? Take part in our online info event on 14 August 2025. Submission deadline: 4 November 2025 ➡️ buff.ly/dDQl9QA
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PlantEvolution 🌱🌾 @plantevolution.bsky.social · 30/07/2025
I’ve been mystified for years why my line of research (which includes genetic engineering of plants) makes (German) people so much more upset than the AI work of my campus neighbors. And why does eco-anxiety have a @wikipedia.org page, but not AI-anxiety?
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Carlos Rodríguez @carloslab.bsky.social · 27/07/2025
Also, I can tell you exactly all the components on your sample with a single test, including concentrations and place of origin! That's why my screen has all these spinning structures.
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Julie (unprofessional) @juliebalt.bsky.social · 27/07/2025
Hello, I am a scientist in a film. All my liquids are brightly coloured. The time it takes to perform tests and experiments is dependent on plot requirements, not biology or chemistry. Also, my safety glasses are extremely stylish.
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Kingfisher & Wombat @tkingfisher.com · 26/07/2025
Fiiiine, apparently half my readers enjoy an info dump, so here we go! Grasslands Sequester Carbon Too or “Why trees are not the be-all and end-all.” Ahem. *takes a sip of water*
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Stacey D. Smith @iochromaland.bsky.social · 05/05/2025
We owe this confidence to generations of scientists who pushed the boundaries of knowledge, not knowing if their efforts would make a difference. Oliver and Schafer didn’t put calf adrenal extracts into dogs to save my son but because they thought the world should know what adrenal glands do. 20/n
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FrankeLab @frankelab.bsky.social · 18/03/2025
Started as a very successful master thesis, now published in JACS. Screening sequence similarity networks turned out to be a great way to discover oxidosqualene cyclases with unusual activity from more than thousand plant transcriptome sequence datasets. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Expansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants
Triterpenoids and steroids are structurally complex polycyclic natural products with potent biological functions, for example, as hormones. In all eukaryotes, the carbon skeletons of these compounds a...
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Dr. Damien P. Williams, dread portent down from a mountain cave @wolven.blacksky.app · 24/04/2025
Authoritarians love "Gen AI" because it - Sounds confident even when factually wrong - Broadly conforms to & reproduces their biases, off the shelf - Lets them create bespoke realities (text, audio, moving & still image) which agree w/ their biases - Degrades trust in knowledge/evidence/expertise…
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Pingtao Ding (he/him) @dinglab.bsky.social · 23/07/2025
Three back-to-back Salicylic Acid biosynthesis papers 1/3 www.nature.com/articles/s41...
nature.com
Three-step biosynthesis of salicylic acid from benzoyl-CoA in plants - Nature
The salicylic acid (SA) biosynthesis pathway—involving ligation of benzoyl coenzyme A and benzyl alcohol to give benzyl benzoate; hydroxylation of benzyl benzoate to give benzyl salicylate; and cleava...
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Phytochemical Society of North America @psna-official.bsky.social · 24/06/2025
The 64th Annual Meeting of the Phytochemical Society of North America (#PSNA2025) starts today at York University, Toronto. We welcome all attendees to dive into groundbreaking phytochemical research, vibrant networking, and fun experiences! #PlantScience #Phytochemisty Download detailed programme
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Richard Sever @richardsever.bsky.social · 04/06/2025
"a fascinating case study on the limits of AI in biology and the harms of current publishing incentives" rachel.fast.ai/posts/2025-0...
rachel.fast.ai
Rachel Thomas, PhD - Deep learning gets the glory, deep fact checking gets ignored
an AI researcher going back to school for immunology
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Carlos Rodríguez @carloslab.bsky.social · 20/06/2025
Highly recommended read on the discovery of a very, very elusive enzyme!
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Conor McClune @cmcclune.bsky.social · 11/06/2025
Today in Nature we report a systematic strategy to activate & identify gene sets in plants. We identify 8 new genes from the yew tree's Taxol biosynthetic pathway, enabling us to engineer tobacco with 17- & 20-gene pathways to Taxol precursors baccatin III & deBz-deoxy-Taxol #SingleCell #secmet 🧬🧪🌾
nature.com
Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III - Nature
An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose&nbsp;curren...
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FrankeLab @frankelab.bsky.social · 11/06/2025
Fantastic work by the Sattely group on taxol biosynthesis, featuring a highly innovative application of single nuclei sequencing to find elusive biosynthetic genes 👏 www.nature.com/articles/s41...
nature.com
Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III - Nature
An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose&nbsp;curren...
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Neftaly Cruz Mireles @neftalycm.bsky.social · 01/06/2025
Hi everyone! I’m new to Bluesky. At the beginning of the year, I moved to Zurich @UZH_en to start a postdoc with #CyrilZipfel and @pedrobeltrao.bsky.social, investigating protein phosphorylation in plants 🌱 If you’re nearby or working on something similar, let’s connect 😀
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Maite Colinas @maitecolinas.bsky.social · 23/05/2025
New preprint out from the @oconnorlab.bsky.social department led by Moonyoung Kang, Anh Vu and Lorenzo Caputi. Metabolomics and RNA-seq on the same single cell! Or as we call it here in the lab: "the split-cell method"
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Sebastian S. Cocioba @atinygreencell.bsky.social · 02/05/2025
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚
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geufloreslab.bsky.social @geufloreslab.bsky.social · 16/04/2025
We're hiring! 🥼 2-year lab technician at UCPH from 01 Aug 🌿 Support our research in plant natural products with relevance in agriculture, nutrition, and medicine. 🧬 Your skills: plant molecular biology and/or tissue culture & transformation 📅 Deadline 18 May 2025 jobportal.ku.dk/administrati...
jobportal.ku.dk
Laboratory Technician, Department of Plant and Environmental Sciences
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Phytochemical Society of North America @psna-official.bsky.social · 11/03/2025
Hello Bluesky! 🎉 The Photochemical Society of North America☘️ is here! We'll be sharing all the latest updates on PSNA2025. Don't miss out on early bird registration – it's still available! Join us! #PSNA2025 #Photochemistry #Science www.psna2025.com/register
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Carlos Rodríguez @carloslab.bsky.social · 27/03/2025
Is anyone else having problems with MASSive? Anyone know if the repository is going to remain active? #MassSpec
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Max Planck Institute for Chemical Ecology @mpi-ce.bsky.social · 27/03/2025
Our director Sarah O'Connor, head of the Department of Natural Product Biosynthesis @oconnorlab.bsky.social, has has been elected a member of the German National Academy of Sciences, the #Leopoldina! Congratulations! 👏 www.ice.mpg.de/492460/sarah...
ice.mpg.de
Sarah O'Connor is a new member of the Leopoldina
Sarah O'Connor has been elected as a new member of the Leopoldina's Section for Organismic and Evolutionary Biology. Election to the oldest scientific society in the German-speaking world is one of th...
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