Abstract. High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective evidence-based therapy for Parkinson’s disease; howe

Goede et al. combined multiple modalities to define a common tremor network across disorders. This finding may help optimize deep brain stimulation and guide future noninvasive therapies.

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Background and ObjectivesParkinson disease (PD) exhibits a characteristic pattern of brain perfusion or metabolism, thereby being considered network disorder. Using dual-phase N-(3-fluoropropyl)-2β-ca...

Objective The objective of this study was to obtain individual clinical and neuroimaging data of patients undergoing deep brain stimulation (DBS) for essential tremor (ET) from 5 different European ...

Background Subthalamic nucleus deep brain stimulation (STN-DBS) effectively treats motor symptoms and quality of life (QoL) of advanced and fluctuating early Parkinson's disease. Little is known abo...

Al-Fatly et al. establish predictive connectivity maps of deep brain stimulation in essential tremor. They demonstrate that electrode connectivity to tremo

Chen et al. identify a fast, non-stop pathway between the prefrontal cortex and subthalamic nucleus in humans using multisite invasive brain recordings. This pathway is critically involved in the stopping of ongoing actions. Modulation of this pathway may be a means of treating disorders of inhibitory control, such as impulsivity.