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Brain Communications

@braincomms.bsky.social
384 followers 36 following 901 posts

Open Access sister journal to Brain. 🧠🧠🧠 Proceeds go to Guarantors of Brain Charity to support the translational neuroscience community. Join our community of authors, reviewers, prize winners!

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Brain Communications @braincomms.bsky.social · 13h
Filip et al. link long COVID to cognitive impairment and altered cerebral microstructure. The prominence of neuroinflammation-sensitive MRI in the modelled latent axis suggests immune and vascular rather than neurodegenerative substrate. Read it at 👉https://buff.ly/7Wbbp0V #neuroscience #longcovid
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Brain Communications @braincomms.bsky.social · 29/09/2026
D’Amelio et al. report that, in a triple-transgenic Alzheimer’s disease mouse model, susceptibility to retroactive interference reveals early, sex-specific memory fragility before overt deficits appear. Read it at 👉https://buff.ly/bqkae4S #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 28/09/2026
Fujita et al. report that serial MRI up to 15 years reveals marked individual differences in brain volume loss among cognitively normal adults, including rapid-atrophy and atrophy-resistant phenotypes linked to modifiable lifestyle factors. Read it at 👉https://buff.ly/eec4u3P #braincommunications
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Brain Communications @braincomms.bsky.social · 27/09/2026
Rhymes et al. report that ciliary neurotrophic factor selectively slows the retrograde transport of signalling endosomes in motor neurons in vivo, highlighting the specificity with which neurotrophic factors shape axonal transport and motor neuron connectivity. Read it at 👉https://buff.ly/jfwxif1
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Brain Communications @braincomms.bsky.social · 26/09/2026
What Kafka’s Metamorphosis reveals about consciousness without communication? In his essay, Demas uses Gregor Samsa’s example to explore the limits of observable behaviour as a measure of consciousness. Read it at 👉https://buff.ly/4vwMY2D #neuroscience #braincommunications
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What Kafka’s Metamorphosis reveals about consciousness without communication
Gregor Samsa awakens transformed. His body has become unrecognizable, his movements incoherent and his voice unintelligible. Yet nothing in his inner life
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Brain Communications @braincomms.bsky.social · 25/09/2026
Meet Prof Tiago Outeiro, Professor at Newcastle University and Director of the Department of Experimental Neurodegeneration at the University Medical Center Goettingen 👋 He researches the molecular basis of neurodegenerative disorders, fousing on Alzheimer’s and Parkinson’s disease. #meettheteam
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Brain Communications @braincomms.bsky.social · 24/09/2026
Thompson et al. report the generation and characterization of novel gene-edited mice expressing the human superoxide dismutase 1 (SOD1) gene and carrying the pathogenic SOD1A5V mutation associated with amyotrophic lateral sclerosis. Read it at 👉https://buff.ly/J8mz8dt #neuroscience #ALS
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Brain Communications @braincomms.bsky.social · 23/09/2026
Orlando et al. show that heart rate variability is preserved in people with Parkinson’s disease receiving an acute dose of atomoxetine, supporting a safe cardiovascular profile for the drug. Read it at 👉https://buff.ly/hvluO1e #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 22/09/2026
Falconer et al. report that dynamic functional connectivity predicts treatment response in post-stroke aphasia with higher temporal variability, greater community stability, and more time spent in a high-modularity state predicting greater gains. Read it at 👉https://buff.ly/x3goq2v #neuroscience
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Brain Communications @braincomms.bsky.social · 21/09/2026
Lukyova et al. provide an overview of the genetic background of Alzheimer’s disease in the era of next-generation sequencing, highlighing mechanisms that may explain missing heritability and the potential of multi-omics for precision medicine. Read it at 👉https://buff.ly/tJgmAVp #neuroscience
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Brain Communications @braincomms.bsky.social · 20/09/2026
Sintini et al. report that MRI and 18F-FDG PET principal components diagnostic outperformed tau-PET, with the highest sensitivity for the semantic variant of primary progressive aphasia and progressive supranuclear palsy. Read it at 👉https://buff.ly/lLfZKxN #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 19/09/2026
Meier et al. found that increase in white matter volume, diffusivity and inositol, and abnormal magnetization transfer indicate pre-symptomatic white and grey matter involvement in asymptomatic adolescent adrenoleukodystrophy patients. Read it at 👉https://buff.ly/TbzGb2P #neuroscience
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Brain Communications @braincomms.bsky.social · 19/09/2026
The letter to the editor by Kapadia et al. highlights that the study by Bechkos et al. (2026) independently corroborate previous evidence that electrical stimulation reduces α-synuclein oligomerisation in Parkinson’s disease models. Read it at 👉https://buff.ly/c3RWM5j #neuroscience
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Modulating α-synuclein clearance: a comparison of high-frequency and direct current stimulation in preclinical models of Parkinson's disease
Parkinson’s disease involves degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). A defining pathological hallmark is misfold
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Brain Communications @braincomms.bsky.social · 18/09/2026
Meet Alfred Kongnyu Njamnshi, a Professor of Neurology and Neuroscience at the University of Yaoundé I and the founder of Brain Research Africa Initiative (BRAIN)👋 His team studies neurological and cognitive effects of parasitic infections, HIV and stroke-related neurocognitive disorders and sleep.
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Brain Communications @braincomms.bsky.social · 18/09/2026
Zoellin et al. report that autologous haematopoietic stem cell transplantation is associated with reduced retinal tissue loss in relapsing-remitting multiple sclerosis, with baseline inner nuclear layer thickness predicting better outcomes. Read it at 👉https://buff.ly/qTHPDO4 #neuroscience
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Brain Communications @braincomms.bsky.social · 17/09/2026
Pini et al. review developmental biomarker changes and propose that elevations of p-tau217 and glial fibrillary acidic protein in Alzheimer'’s disease may reflect unresolved adaptive brain programmes rather than intrinsically toxic responses. Read it at 👉https://buff.ly/epphj5D #neuroscience
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Brain Communications @braincomms.bsky.social · 17/09/2026
Leveraro et al. report that patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder show altered functional brain organization despite preserved cognition. Read it at 👉https://buff.ly/BOaMba0 #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 16/09/2026
Conti et al. report that impaired awareness of visual hallucinations in Lewy body disease involves reduced resting-state connectivity between right visual association and prediction-error systems. Read it at 👉https://buff.ly/ItuMXvA #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 16/09/2026
Xiong et al. report that susceptibility-weighted MRI of the substantia nigra and adjacent structures, analysed with a multi-task deep learning model, predicts motor outcome after subthalamic nucleus deep brain stimulation in Parkinson’s disease. Read it at 👉https://buff.ly/oLYnHD2 #neuroscience
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Brain Communications @braincomms.bsky.social · 15/09/2026
Norouzi et al. studied periodic and aperiodic resting-state features in Parkinson’s patients across six EEG and MEG datasets, finding elevated alpha power, slower alpha peak frequency, and higher aperiodic offset and exponent. Read it at 👉https://buff.ly/ouVad3F #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 15/09/2026
Keute et al. report that verbal and visuospatial working memory outcomes after deep brain stimulation in Parkinson’s disease were linked to baseline cortical activity and stimulation-related spectral changes. Read it at 👉https://buff.ly/IVZQIgn #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 14/09/2026
Braun et al. report that human synucleinopathy is associated with mislocalization of the astroglial water channel aquaporin-4 and glymphatic clearance of alpha-synuclein is impaired in a transgenic mouse model with loss of perivascular aquaporin-4. Read it at 👉https://buff.ly/KfcwH7V #neuroscience
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Brain Communications @braincomms.bsky.social · 14/09/2026
Oatman et al. studied how brain gene expression relates to levels of key Alzheimer’s disease proteins: amyloid-β, tau, and APOE. Most changes were related to levels of tau protein. Read it at 👉https://buff.ly/HmQxdUW #neuroscience
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Brain Communications @braincomms.bsky.social · 13/09/2026
Meron et al. report reduced neural responsivity to startling stimuli in post-ictal larval zebrafish, alongside increased receptor density at inhibitory glycinergic synapses. Disrupting these receptors restores responsivity. Read it at 👉https://buff.ly/uYmo0Lj #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 13/09/2026
Ringshaw et al. demonstrated that antenatal maternal anaemia may impact child brain structure as early as infancy, with detectable effects from 12 months of age, using ultra-low-field MRI. Read it at 👉https://buff.ly/sFq2qiG #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 12/09/2026
Goret et al. characterize a Dnm2K562E/SC− mouse model combining a heterozygous K562E dynamin-2 mutation with Schwann cell-specific deletion, capturing key Charcot–Marie–Tooth features. Dynamin-2 delivery after disease onset didn't reverse disease. Read it at 👉https://buff.ly/VHDOtO5 #neuroscience
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Brain Communications @braincomms.bsky.social · 12/09/2026
Malfer et al. report 69.3% 20-year dementia incidence in a parkinsonism cohort (67.8% in Parkinson’s disease), with risk linked to impaired postural reflexes, orthostatic hypotension, smooth pursuit alterations, and reduced ocular range of motion. Read it at 👉https://buff.ly/G7I6xyy #neuroscience
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Brain Communications @braincomms.bsky.social · 11/09/2026
Meet Dr Roisin McMackin, an Assistant Professor of Physiology at Trinity College Dublin 👋 She leads a research team studying neural network dysfunction in health and neurodegenerative diseases, focusing on amyotrophic lateral sclerosis and Huntington’s disease. #meettheteam #braincommunications
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Brain Communications @braincomms.bsky.social · 11/09/2026
Aldridge et al. report 319 genetic variants associated with multiple stroke recovery domains. Genome-wide analyses across 6 recovery domains in 565 participants further identified variants linked to neural plasticity genes. Read it at 👉https://buff.ly/NPlsvrA #neuroscience
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Brain Communications @braincomms.bsky.social · 10/09/2026
Laginha et al. report consistently reduced plasma and CSF prion protein (PrP) in D178N carriers, supporting plasma PrP as a promising pharmacodynamic biomarker for PrP-lowering trials for prion diseases. Read it at 👉https://buff.ly/aiVaEky #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 10/09/2026
Using clinically acquired brain MRI from 442 individuals with focal epilepsy, Ndagijimana et al. demonstrate that hippocampal volumetric asymmetry is a robust marker of pathologically confirmed hippocampal sclerosis. Read it at 👉https://buff.ly/MBycQLp #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 09/09/2026
Griffiths-King et al. proposed a convolutional neural network approach for automated segmentation of paediatric brain tumours, exclusively from diffusion-weighted MRI (DWI), demonstrating the feasibility of this approach with a Dice score of 0.63. Read it at 👉https://buff.ly/rY5tS7Y #neuroscience
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Brain Communications @braincomms.bsky.social · 09/09/2026
Camastra et al. report that rapid eye movement sleep behaviour disorder, depression and anxiety in Parkinson’s disease show converging structural changes that map onto shared attention networks and are spatially aligned with the noradrenergic system. Read at 👉https://buff.ly/Hwom2B9 #neuroscience
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Brain Communications @braincomms.bsky.social · 08/09/2026
Unlu Kobya et al. show that neuron-derived orphan receptor 1 is reduced in the motor cortex of multiple sclerosis and is associated with increased inflammation and ageing. Read it at 👉https://buff.ly/XUY3AVr #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 08/09/2026
A correction was published to: Jang and Kim et al., "Long-term effects of preterm birth on cortical folding trajectories in early childhood". Read it at 👉https://buff.ly/XBemfwM #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 07/09/2026
Doyon et al. found that individuals with narrower anterior choroidal arteries, which supply the anterior portion of the medial temporal lobe, have higher tau burden and experience faster cognitive decline. Read it at 👉https://buff.ly/cO1Omz4 #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 07/09/2026
Jomsky et al. report that combining structural MRI with synthesized measures of cerebral blood volume improves the estimation of brain age and enhances sensitivity to pathological brain ageing. Read it at 👉https://buff.ly/cwMmhj7 #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 06/09/2026
Li et al. found that alcohol use disorder is associated with increased intron retention in the human brain, replicated in rats. Retained introns may form double-stranded RNA, potentially driving neuroinflammation and cell death. Read at 👉https://buff.ly/84ZzZCn #neuroscience
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Brain Communications @braincomms.bsky.social · 06/09/2026
Boscolo Galazzo et al. found cortical and subcortical hypoperfusion in Multiple Sclerosis compared with controls. Hypoperfusion rarely co-localized with structural changes in grey matter and didn't differ across MS phenotypes. Read it at 👉https://buff.ly/LaQUfMM #neuroscience
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Brain Communications @braincomms.bsky.social · 05/09/2026
Eisenstein et al. report that, in a sample of 53,000 participants, men exhibit higher nigrosome-1 magnetic susceptibility than women across mid-to-late adulthood, independent of ageing trajectories or genetic, lifestyle or cardiometabolic factors. Read it at 👉https://buff.ly/XHBBcbf #neuroscience
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Brain Communications @braincomms.bsky.social · 05/09/2026
Ölmestig et al. studied whether daily tadalafil could improve brain blood flow in people with stroke and small vessel disease. Tadalafil increased overall brain blood flow but not the response during brain activity. Read it at 👉https://buff.ly/plVUx0W #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 04/09/2026
Meet Dr Isabel Martín-Monzón, an Associate Professor of Psychobiology at the University of Seville in Spain 👋 Her current research focuses on brain neuromodulation aimed at enhancing cognitive processes and strengthening stress resilience. #meettheteam #braincommunications
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Brain Communications @braincomms.bsky.social · 04/09/2026
Bottale et al. report impaired glymphatic function in motor neuron disease, using DTI-ALPS. Altered perivascular space diffusivity relates to bulbar onset of symptoms, longer disease duration, sleep problems and white-matter damage. Read it at 👉 buff.ly/SlCIl3a #neuroscience
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Brain Communications @braincomms.bsky.social · 03/09/2026
Karra et al. used a national geospatial index of resource scarcity and found that community disadvantage is negatively correlated with inhibitory control in sons with Duchenne muscular dystrophy and with cognitive flexibility in biological mothers. Read 👉 doi.org/10.1093/brai... #neuroscience
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Brain Communications @braincomms.bsky.social · 03/09/2026
Xing et al. demonstrated that cortico-cortical paired associative stimulation targeting the primary motor cortex and supplementary motor area reorganized large-scale brain network connectivity in stroke patients. Read it at 👉 doi.org/10.1093/brai... #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 02/09/2026
Trudel et al. report that atypical Alzheimer’s disease syndromes are highly specific indicators of autopsy-confirmed Alzheimer’s disease pathology. Read it at 👉 doi.org/10.1093/brai... #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 02/09/2026
Lam et al. report that specific white matter pathways support sleep rhythms important for memory. Read it at 👉 doi.org/10.1093/brai... #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 02/09/2026
Srikrishna et al. report that automated CT analysis accurately identifies imaging features of idiopathic normal pressure hydrocephalus. Read it at 👉 doi.org/10.1093/brai... #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 01/09/2026
Liu et al. report multiday bilateral intracranial EEG recordings in chronic neuropathic pain. Read it at 👉 doi.org/10.1093/brai... #neuroscience #braincommunications
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Brain Communications @braincomms.bsky.social · 01/09/2026
Brown et al. demonstrate the T-cell responses to NR1-derived peptides in patients with NMDA receptor antibody-associated encephalitis and healthy individuals. Read it at 👉 doi.org/10.1093/brai... #neuroscience #braincommunications
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