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Aakanksha Singhvi

@singhvilabglia.bsky.social
2.1K followers 425 following 69 posts

Associate Prof @Fred Hutch (+ @UW_NBio) Glia fascinate me. Worms are rad. singhvilab.org

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Reposted by Aakanksha Singhvi
Ben Williamson @benpatrickwill.bsky.social · 19/12/2025
Closing out my year with a journal editor shocker 🧵 Checking new manuscripts today I reviewed a paper attributing 2 papers to me I did not write. A daft thing for an author to do of course. But intrigued I web searched up one of the titles and that's when it got real weird...
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Jonathan Pettitt @genotripe.bsky.social · 28/11/2025
C. elegans researchers were early adopters of open science: "The development of common resources and the belief that research findings and mutant strains should be freely shared has propelled worm research to the forefront" www.pnas.org/doi/10.1073/...
pnas.org
From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism | PNAS
Experimental organisms such as the nematode Caenorhabditis elegans are fundamental to biological discovery. The success of C. elegans research has ...
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Monika Scholz @monikakscholz.bsky.social · 26/11/2025
The open source spirit of the worm community makes it so special - and so powerful for discovery! Great account of the impact of the community tools and databases had and have on understanding fundamental biology! 🪱 www.pnas.org/doi/10.1073/... Important to keep these resources funded!
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Aakanksha Singhvi @singhvilabglia.bsky.social · 23/11/2025
Yes, lab life is truly so much fun! So nicely said by Donna Strickland: www.facebook.com/reel/8264683...
facebook.com
210K views · 5.7K reactions | Throwback to 2018 when physics laureate Donna Strickland started her banquet speech by talking about Cyndi Lauper's song 'Girls Just Want To Have Fun'. Strickland told ...
Throwback to 2018 when physics laureate Donna Strickland started her banquet speech by talking about Cyndi Lauper's song 'Girls Just Want To Have Fun'. Strickland told us how enjoyable she found...
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 06/11/2025
If said women work for your competitors, I guess maybe
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Meera Sundaram @meera-sundaram.bsky.social · 11/10/2025
Reaffirming the value of model organisms in training scientific minds @ishmailsaboor.bsky.social exactly what we were talking about re your #Celegans background setting you up for creative work in other systems! www.nature.com/articles/s41...
nature.com
Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology
As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.
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Karolinska Institutet @ki.se · 06/10/2025
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...
Photo: Cecilia Odlind
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PLOS Biology @plosbiology.org · 29/09/2025
How are #circadian rhythms established during development? This study shows that maternal metabolic signals oscillate in the fetal #SCN before the endogenous #clock becomes functional, offering a plausible mechanism for maternal entrainment of the developing clock @plosbiology.org 🧪 plos.io/3VD45fZ
Rhythmic metabolites in the E19 SCN peak during the day. Majority of rhythmic lipids and polar metabolites in the E19 SCN peak during the day, while there are more diverse phase clusters in the developed P28 SCN postweaning. Polar metabolites and lipids identified as rhythmic in E19 SCN (E19 clusters 1, top, and 2, bottom) were divided into subgroups based on hierarchical K-means clustering. Line plots on the left show traces of the normalized level of each rhythmic compound in each corresponding cluster. Bar plots on the right represent the lipid classes and polar metabolites in each rhythmic cluster.
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Drug Monkey @drugmonkey.bsky.social · 25/09/2025
This may be the most important paper ever published about NIH funded research. www.science.org/doi/10.1126/...
science.org
What if NIH had been 40% smaller?
Replaying history with less NIH funding shows widespread impacts on drug-linked research
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Piali Sengupta @senguptalab.bsky.social · 13/09/2025
Whoa - neuronal ciliary proteome! Tons to dig into here - different from kidney cilia proteome (perhaps unsurprising) and enriched for many postsynaptic proteins, strengthening previous suggestions of cilia as postsynaptic signaling structures. @nachury.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
In situ Proteomics Unveils Specialized Domains for Extrasynaptic Signaling on Neuronal Cilia
Neuronal cilia have emerged as crucial signaling hubs, yet their molecular composition and integration with synaptic communication remain poorly understood. Using a newly developed Arl13b-TurboID mous...
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Travis Faust @travisfaust.bsky.social · 12/09/2025
Thrilled to share our new paper @cp-cell.bsky.social: “Microglia–astrocyte crosstalk regulates synapse remodeling via Wnt signaling.” This work demonstrates the necessity of glia–glia communication and coordination during synapse remodeling. 🔗 www.cell.com/cell/fulltex... Faust et al., Cell 2025
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John Borghi @johnborghi.bsky.social · 20/08/2025
A friendly reminder that the NIH Public Access Policy IS NOT “you must publish open access” but rather “you must ensure your copy of your paper is deposited into PubMed Central.” Yes, it is very confusing. Yes, you should be able to do that deposit yourself without paying anything to a journal.
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Kavita Babu @kavita-babu.bsky.social · 27/02/2025
The first one is some crazy work by @monmitabhar.bsky.social, Tanumoy, @hari-flies.bsky.social and Kamal Kishore. They eavesdropped on worm conversations and found the exciting phenomenon of movement of memory from one worm to another 2/n www.biorxiv.org/content/10.1...
biorxiv.org
Extracellular vesicles aid in the transfer of long-term associative memory between Caenorhabditis elegans
Memory formation is necessary for the survival of animals across phyla. Here, we elucidate the mechanism underlying the formation of long-term associative memory (LTAM) formed by treating Caenorhabdit...
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Neuromatch @neuromatch.bsky.social · 18/08/2025
📣 Calling all early career #neuroscientists! @thetransmitter.bsky.social & Neuromatch are teaming up to better understand how to support #EarlyCareer Researchers. Whether you're a student, postdoc, or launching your career, we want to hear from you. ➡️ www.thetransmitter.org/early-career...
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Fred Hutch @fredhutch.org · 29/07/2025
Fred Hutch researchers created a gene-expression map of glial cells in tiny worms, adding the missing component that completes an atlas of the entire nervous system of a multicellular adult animal at the molecular level. @singhvilabglia.bsky.social @manusetty.bsky.social bit.ly/47353c3
bit.ly
Mapping molecules of an unsung brain cell
Fred Hutch researchers have created a gene-expression map of glial cells of the tiny worm, C. elegans, adding the missing component that completes for the first time an atlas of the entire nervous sy...
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John Wallingford @jbwallingford.bsky.social · 29/07/2025
Great opportunity here to build your skills and your professional network! Apply for the SciComm Interns program! #devbiolwriteclub @socdevbio.bsky.social
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John Wallingford @jbwallingford.bsky.social · 29/07/2025
Interested in science administration? Want to meet and work with senior members of the SDB? Want to help chart the future of the SDB? Then apply for the Strategic Planning Internship! @socdevbio.bsky.social www.sdbonline.org/strategic_pl...
sdbonline.org
Society for Developmental Biology | Strategic Planning Internship
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Shane Liddelow @liddelowsa.bsky.social · 22/07/2025
fantastic work from @melcooperphd.bsky.social - what are these beautiful networks doing in our brains?
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Hadley Bergstrom @hadleybergstrom.bsky.social · 17/07/2025
Vassar College is seeking a biologist with a focus on Developmental Neurobiology on the tenure-track. Please spread widely! vassar.wd1.myworkdayjobs.com/en-US/Vassar...
vassar.wd1.myworkdayjobs.com
Assistant Professor of Biology, Tenure Track
Department Biology Vassar College is dedicated to providing equal employment opportunities to all applicants and employees and welcomes applications from individuals of all backgrounds. Decisions conc...
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K.T. Elliott @ktelliottmicro.bsky.social · 17/07/2025
🚨🚨🚨PUI TT Job Alert!! My dept at TCNJ is hiring a tenure track cell and molecular biologist. Come join my supportive colleagues, helpful staff, & fabulous students! We're surprisingly well resourced w/excellent equipment (confocal, SEM etc) and research w/students counts towards our teaching load!
tcnj.taleo.net
Assistant Professor - Biology
Click the link provided to see the complete job description.
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Miriam B. Goodman, PhD @wormsense.bsky.social · 16/07/2025
Hey 🧪 I’m looking for a sci-savvy illustrator to build a cartoon-style schematic for a paper about summer research experiences. HMU if this describes you or your side gig.
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John Tuthill @tuthill.bsky.social · 14/07/2025
i wrote an essay for @thetransmitter.bsky.social about what it feels like to serve on an NIH grant review panel (study section) right now www.thetransmitter.org/craft-and-ca...
thetransmitter.org
Fear and loathing on study section: Reviewing grant proposals while the system is burning
As grants are canceled, delayed and subject to general uncertainty, participating in study sections can feel futile. But it’s more important than ever.
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Aakanksha Singhvi @singhvilabglia.bsky.social · 14/07/2025
Firat ever Singhvi lab "reunion" at a meeting (how did we get this old a lab already? 🤔🫢😲) -with Liza Severs, Sasha Kravchuk, & alum @glia-maria.bsky.social #worm25
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Jason Shepherd @jasonsynaptic.bsky.social · 12/07/2025
www.genengnews.com/topics/trans...
genengnews.com
Why We Still Need Animal Research in a World of AI and Organoids
The portrayal of uncaring scientists without any thought for the animals being used in their research is far from the truth.
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Dr. Ahna Skop @ahnaskop.bsky.social · 04/07/2025
2025 Worm Show youtu.be/HXgUZzLJ-b0?...
youtu.be
Worm Show 2025
YouTube video by Morris Maduro
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callista yee @csybio.bsky.social · 02/07/2025
c. elegans, ba-ba-bah #worm25
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Aakanksha Singhvi @singhvilabglia.bsky.social · 02/07/2025
Absolutely agree! #Worm25 @genetics-gsa.bsky.social was amazing on many levels.. Thank you @cswormlab.bsky.social and @baristursun.bsky.social ..and cheers to the fabulous worm community!!👏🏼❤️
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Franki Compere M.S @misscelegans.bsky.social · 02/07/2025
Worm comedy show #worm25 this year was amazing, it made my 4th worm meeting very special, thank you!!
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Aakanksha Singhvi @singhvilabglia.bsky.social · 01/07/2025
Congratulations to all the 2025 awardees!! 👏🏼
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Laura Herndon @enchiladalaura.bsky.social · 01/07/2025
It doesn’t get any more classic than this #worm25
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Aakanksha Singhvi @singhvilabglia.bsky.social · 01/07/2025
Such a blast to hang out with these badass Women of Worms (WoW!!) #Worm25 @ahnaskop.bsky.social @senguptalab.bsky.social @barrlab.bsky.social
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Liz Ronan, PhD @elizabithian.bsky.social · 30/06/2025
“Do you have any advice for aspiring young scientists?” “Do genetics.” *mic drop* #worm25
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Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · 29/06/2025
For #worm25, here are updated lists of 200+ researchers for the #Celegans community to easily follow: C. elegans #1 (150 full) - go.bsky.app/HP1h3nW C. elegans #2 (50+) - go.bsky.app/J7soTHG ==> Reply to this if you'd like to be added! cc: @genetics-gsa.bsky.social #CeleganSky 🪱 🧪 1/n
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Swathi Arur @swathiarur.bsky.social · 29/06/2025
And to you and your student for the inaugural Brenner award last year!!!! 🙌🏽
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Max Heiman @heiman.bsky.social · 27/06/2025
This opens up (literally) a lot of possibilities! I thought the eggshell was needed as a mechanical constraint for morphogenesis. This image of a comma stage embryo happily letting it all hang out in the world with nothing around it is wild!
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Aakanksha Singhvi @singhvilabglia.bsky.social · 28/06/2025
A happy smiling start traveling to #worm25 with the fun @linadahlberg.bsky.social !!
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Dan Garisto @dangaristo.bsky.social · 24/06/2025
NEW: NSF will be kicked out of their building. Announcement will be made tomorrow by HUD Sec. and Governor of VA. HUD will take over the NSF building over the next two years. NSF staffer: "There is no planning for NSF, no identified future location, appropriation for a new building or a move."
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Meital Oren @meital.bsky.social · 25/06/2025
C. elegans enthusiasts - join me and @stern-lab.bsky.social ‪‪for a pre #worm25 meeting online workshop on *Monitoring inter-individual diversity across multiple levels and timescales* - Jun 26, 2025 12:30 PM Eastern Time us06web.zoom.us/j/8544967372... please share!
us06web.zoom.us
Join our Cloud HD Video Meeting
Zoom is the leader in modern enterprise cloud communications.
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Nikki Zabik, PhD @neurozabik.bsky.social · 21/06/2025
Plugging my favorite website for multi-color figures davidmathlogic.com/colorblind/#...
davidmathlogic.com
Coloring for Colorblindness
This interactive visual tool lets you see how accessible your color palettes are to viewers who are colorblind.
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John Murray @jisaacmurray.bsky.social · 20/06/2025
Happy to announce our paper comparing embryonic gene expression between C. elegans and C. briggsae, work led by Christopher Large with Rupa Khanal and in collaboration with Junhyong Kim and Bob Waterston. www.science.org/doi/10.1126/...
science.org
Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae
The constraints that govern the evolution of gene expression patterns across development remain unclear. Single-cell RNA sequencing can detail these constraints by systematically profiling homologous ...
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Aakanksha Singhvi @singhvilabglia.bsky.social · 16/06/2025
Happy to present a single cell atlas of ALL glia, in BOTH sexes of an animal (in vivo validated!)! Fab work by postdoc @glia-maria.bsky.social, team, & collaboration with @manusetty.bsky.social . Find insights into glia, new analytics and ML models, and browse our companion website (wormglia.org)
wormglia.org
React App
Web site created using create-react-app
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Aakanksha Singhvi @singhvilabglia.bsky.social · 11/06/2025
Thank you @klingensteinorg.bsky.social Philanthropies team and Klingenstein family for a fantastic conference (as always), and support of our research! It was a blast to share our recent work and talk science with this fab group of fellow neuroscientists and Scientific Committee members.
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Aakanksha Singhvi @singhvilabglia.bsky.social · 07/06/2025
Super-worm alert! Worms make Castells (super-organism pyramid/tower) to disperse...! Whoaw - Together They Stand. Congratulations to Siyu Serena Ding and team for this cool insight: www.cell.com/current-biol...
cell.com
Towering behavior and collective dispersal in Caenorhabditis nematodes
Perez et al. report that self-assembling nematode towers occur in nature and can function as collective dispersal structures. Using Caenorhabditis elegans, they establish a tractable empirical model t...
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EMBO Press @embopress.org · 19/05/2025
📣 Job alert: we're looking for a scientific editor at @emboreports.org to provide a 12-month absence cover. Prior editorial experience is not required. For details and to apply: www.embo.org/vacancy/scie...
embo.org
Scientific Editor (Absence cover) – EMBO
About us EMBO is a not-for-profit organization dedicated to promoting excellence in the life sciences in Europe and beyond. We fund talented researchers at all career stages, facilitate scientific exc...
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Aakanksha Singhvi @singhvilabglia.bsky.social · 08/05/2025
Agree, this one was a blast! Thank you @gtavosanis.bsky.social @hilliardlab.bsky.social Claudia Bagni, Nektarios Tabernarakis - and @embo.org - for such a fabulous gathering!!
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gregdfield.bsky.social @gregdfield.bsky.social · 02/05/2025
Attention Vision Scientists. The Jules Stein Eye Institute at UCLA has a faculty position open at the Assistant or Associate Professor level. I'll be at #ARVO2025 so feel free to reach out via DM or email if I can answer any questions. recruit.apo.ucla.edu/JPF10092
recruit.apo.ucla.edu
Vision Science Faculty at UCLA Stein Eye Institute
University of California, Los Angeles is hiring. Apply now!
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Mariko Bennett @nachoriko.bsky.social · 30/04/2025
Our lab's 1st paper, led by @fchrisbennett.bsky.social & @waisenberg.bsky.social. A decade thinking how to directly assess the impact of microglia replacement. Yrs of hard work. This kind of work is needed to expand brain disease care for kids & the vision for safer, more effective cell therapy.
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Elisabeth Bik @elisabethbik.bsky.social · 30/04/2025
The do’s and don’ts of scientific image editing Acceptable image-editing practices are partly a matter of common sense. But researchers say journals and funders could help scientists by standardizing policies. @sarareardon.bsky.social reports www.nature.com/articles/d41...
nature.com
The do’s and don’ts of scientific image editing
Acceptable image-editing practices are partly a matter of common sense. But researchers say journals and funders could help scientists by standardizing policies.
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Javier Apfeld @javierapfeld.bsky.social · 29/04/2025
Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans. Email or DM me to find out more. Please share & repost!
northeastern.wd1.myworkdayjobs.com
Postdoctoral Research Associate, Biology
About the Opportunity Job Summary The Apfeld Lab at Northeastern University is seeking a postdoctoral researcher to investigate how genes work together to determine the maximum lifespan of the nematod...
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Aakanksha Singhvi @singhvilabglia.bsky.social · 29/04/2025
A breath of fresh air and energy - a tribe I love @klingensteinorg.bsky.social in the NYC I love! Blown away by the cool blue sky science, Day 1 of the Fellows meeting!!
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