Abstract. Chemical stressors in environmental and clinical settings can alter conjugative plasmid transfer, which is a key process driving antibiotic resis

Microbial CO2 fixation in alpine grassland soils is highly sensitive to warming and drought. Nitrogen inputs from grazing may stimulate autotrophic nitrifiers, including ammonia-oxidizing archaea (AOA...

Plasmid-mediated dissemination of antibiotic resistance genes (ARGs) is a major driver of antimicrobial resistance (AMR). The nucleoside analogue zidovudine (azidothymidine, AZT) has emerged as a prom...

Combined sewer overflows (CSOs) are a major pathway for untreated wastewater into urban streams, yet their role in shaping antimicrobial resistance (AMR) dynamics remains poorly understood. Here, we u...

npj Clean Water - Reusable immobilised quaternary ammonium particles reduce microbial and resistome burdens without promoting resistance selection during wastewater post-treatment

Abstract. Conjugal plasmid transfer is an efficient mechanism for gene exchange among bacteria. Most bacteria exist in biofilms encased in extracellular po

Antibiotics and heavy metals are widely used in livestock farming to promote animal health and growth, leading to their frequent co-occurrence as contaminants in livestock wastewater. However, their r...

Anthropogenic nitrogen pollution poses a systemic threat to microbial interaction networks and biogeochemical cycling in groundwater ecosystems, yet t…

Abstract. Antibiotic resistance poses a global public health threat, which can originate from the transfer of environmental antibiotic resistance genes to

Livestock wastewater is a crucial source of antibiotic resistance. However, the impact of disinfection byproducts (DBPs), stemming from disinfectants …

Antimicrobial resistance genes that have been mobilized between bacterial species represent a subset of the naturally occurring resistome. Here, the authors compare the abundance, diversity and geogra...

This study investigates the distribution of shear stress in a lab-scale membrane bioreactor consisting of a 56 mm-diameter cylindrical test cell, a 0.…

Fostering collaboration and addressing the interconnected challenges at the interface of human, animal, and environmental health.

Florfenicol treatment substantially increased the abundance and mobility of antibiotic resistance genes (ARGs) in the common carp gut microbiome. The resistome and mobilome profiles failed to return t...

Antibiotic resistance is frequently observed shortly after the clinical introduction of an antibiotic. Whether and how frequently that resistance occurred before the introduction is harder to determin...

npj Antimicrobials and Resistance - Towards the integration of antibiotic resistance gene mobility into environmental surveillance and risk assessment

Carbamazepine (CBZ), a widely used anticonvulsant, is a persistent aquatic micropollutant that withstands biodegradation and accumulates in wastewater-impacted environments. While non-antibiotic pharm...

Abstract. Selection for antibiotic resistance has been demonstrated at low, environmentally relevant antibiotic concentrations. The concept of minimum sele

Background Antimicrobial resistance poses a substantial and growing threat to global health. While antibiotic resistance genes (ARGs) are tracked most closely in clinical settings, their spread remain...

Assessing the risks associated with antibiotic resistance genes (ARGs) in the environment remains challenging due to limited understanding of their distribution and transmission across various media, ...

Antibiotic resistance poses a global public health threat. Cefiderocol, a recently introduced siderophore cephalosporin, employs a 'Trojan Horse' mechanism by exploiting bacterial iron uptake systems ...

Bacteria use molecular weapons such as toxins to outcompete rivals, but their horizontal gene transfer can undermine this advantage. This study shows that horizontal gene transfer of toxin plasmids is...

Antimicrobial resistance (AMR) is a critical global health concern. While AMR research has primarily focused on medical and veterinary settings, the spread of antibiotic-resistant bacteria (ARB) and a...

Aquaculture waters often contain antibiotics, which inhibit the removal of ammonia nitrogen (NH4+-N) by traditional microbial technologies. Thus, it i…

Wastewater treatment plants are important reservoirs of antibiotic resistance genes (ARGs). Here, the authors analyze ARGs in a global collection of samples from wastewater treatment plants across six...

A cellular spike-in metagenomic method for absolute quantification of microorganisms in the aquatic environment is used to develop a risk assessment framework to support informed water quality managem...

AbstractSummary. Currently available and frequently used tools for annotating antimicrobial resistance genes (ARGs) in genomes and metagenomes provide resu

Selection for antibiotic resistance has been demonstrated at low, environmentally relevant antibiotic concentrations. Over the past decade, the concept of minimum selective concentrations (MSC) has be...

Pro Tag werden in Deutschland über 180 Millionen Zigaretten konsumiert. Die TU Dresden hat eine Studie zur Ausbreitung von Keimen aufgrund von Zigarettenstummeln veröffentlicht – mit überraschenden Er...

Conjugative plasmids carrying antimicrobial resistance (AMR) genes are critical for the spread of AMR, due to their ability to transmit horizontally between bacterial hosts. We previously observed tha...

Effective surveillance of antimicrobial resistance (AMR) in the environment is crucial for assessing the human and animal health risk of AMR pollution…

Microbial community structure is affected by phage resistance evolution in Variovorax, which increases host density. Created in BioRender. Castledine, M. (

RP4, RP1, RK2 and R68 were isolated from the multidrug-resistant bacterial wound isolates in 1969 in the Birmingham Accident Hospital, Birmingham, England, and collectively called Birmingham-group Inc...

A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common resistanc...