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Amanda Oakie

@aoakie.bsky.social
151 followers 142 following 8 posts

Postdoctoral fellow, Nostro Lab, McEwen Stem Cell Institute. Islet biology enthusiast.

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Reposted by Amanda Oakie
CIRTN-R2FIC @cirtn.bsky.social · 22/09/2026
The final recap of CIRTN Summer 2026 publications: August🌻! Here are works from the labs of Drs. Devlin, Dhavantari, Hill, Korbutt, Pepper, Lim, Prentki, Rabasa-Lhoret and Shapiro.
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CIRTN-R2FIC @cirtn.bsky.social · 08/09/2026
(🧵1/17) CIRTN labs continued to publish throughout the Summer. We will recap the works three parts. In June, there have been publications from Drs. Ferdaoussi, Gaisano, Hoesli, Kopp, Verchere, Levings, Lynn, P. MacDonald, Nostro, Paraskevas, Rabasa-Lhoret, Riddell, Rideout, Johnson and Rutter.
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Stem Cell Network @stemcellnetwork.ca · 31/08/2026
(1/2) ✨ APPLICATIONS NOW OPEN! SCN has launched a NEW national research funding competition in #RegenerativeMedicine. 🔬 We’re proud to partner with @azrielifoundation.bsky.social and Breakthrough T1D to offer joint-funding opportunities across four programs:
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Stem Cell Network @stemcellnetwork.ca · 11/05/2026
✨ Exciting opportunity at SCN! We’re hiring a Finance Specialist to manage day-to-day accounting and support reporting, audits, and financial operations driving #StemCell and #RegenerativeMedicine research. Learn more and apply. ➡️ stemcellnetwork.ca/careers/
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CIRTN-R2FIC @cirtn.bsky.social · 01/05/2026
(🧵 1/22) Many publications from the CIRTN labs this Spring 🌷! Works are from Drs Bruin, MacDonald, Johnson, Mulvihill, Chen, Verchere, Kolic, Huang, Hull-Meichle, Kin, Shapiro, Korbutt, Pepper, P. MacDonald, T. MacDonald, Rideout, Riddell, Rutter, Rabasa-Lhoret and Prentice.
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Lara Green @laragreen.bsky.social · 10/04/2026
A new step toward cures for type 1 diabetes in Canada. Breakthrough T1D Canada has formally asked the federal government to partner in launching the Breakthrough T1D Network for Canada (BTNC), a national effort to accelerate treatments for #T1D. 💙 Learn more 🔗 ow.ly/yi8850YH60L
ow.ly
A new step toward cures for type 1 diabetes in Canada | Breakthrough T1D
If you live with type 1 diabetes (T1D), or love someone who does, you know how much daily effort it takes to stay healthy and how urgently better treatments and cures are needed. That’s why we want to share an important update. Breakthrough T1D Canada has formally asked the federal government to partner with us […]
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Paraish S. Misra, MD PhD @paraish.bsky.social · 20/03/2026
Excited to share our new paper in Nat Comms on how human stem cell-derived pancreatic progenitors choose between islet and enterochromaffin (EC)-like fates - and how we can steer that choice! A story in a few tweets… Full paper 👉 doi.org/10.1038/s414...
doi.org
Efficient control of enterochromaffin versus islet differentiation from human pluripotent stem cell-derived pancreatic progenitors - Nature Communications
How different islet lineages emerge within pancreatic islets remains largely unknown. Here, using hPSC and mouse models, the authors identify mechanisms that influence islet versus enterochromaffin li...
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CIRTN-R2FIC @cirtn.bsky.social · 19/03/2026
(🧵1/18) Lots of new papers from the members of CIRTN🍀! Here are works from the labs of Drs Mulvihill, Huang, Poitout, Bruin, Johnson, Doucette, Hull-Meichle, Kieffer, Nostro, Prentice, Prentki, Rabasa-Lhoret, Riddell and Shapiro.
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Amanda Oakie @aoakie.bsky.social · 18/03/2026
Hot off the press! This paper provides protocols for directed differentiation of hPSCs to different pancreatic islet-like endocrine cells as well as to enterochromaffin cells. Congratulations to the whole team! www.nature.com/articles/s41...
nature.com
Efficient control of enterochromaffin versus islet differentiation from human pluripotent stem cell-derived pancreatic progenitors - Nature Communications
How different islet lineages emerge within pancreatic islets remains largely unknown. Here, using hPSC and mouse models, the authors identify mechanisms that influence islet versus enterochromaffin li...
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Lara Green @laragreen.bsky.social · 12/03/2026
Breakthrough T1D Canada is pleased to announce three new trainees joining the fourth cohort of our partnership with the Canadian Islet Research and Training Network @cirtn.bsky.social Learn more about their research and the impact of this collaboration: breakthrought1d.ca/breakthrough...
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Lara Green @laragreen.bsky.social · 25/02/2026
Calling all residents and fellows interested in type 1 diabetes #T1D research! Breakthrough T1D Canada's Clinician Investigator Fellowship is currently open for applications. Up to $50,000 salary support per year. Deadline to submit is March 31st. breakthrought1d.ca/research/gra...
breakthrought1d.ca
Breakthrough T1D Canada Clinician Investigator Fellowship Program  | Breakthrough T1D
JDRF Clinician Investigator Fellowships are designed to attract and promote clinician scientists in the field of T1D research. These fellowships are open to medical residents who are pursuing graduate...
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CIRTN-R2FIC @cirtn.bsky.social · 20/02/2026
(🧵1/7) Several publications coming out of CIRTN labs in the first half of February 2026🎉! This includes labs of Drs: Prentice, Riddell and Rutter.
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CIRTN-R2FIC @cirtn.bsky.social · 02/02/2026
(🧵1/23) First month of 2026: complete✅! Many papers coming from CIRTN scientists, including works from the labs of Drs Bruin, Lynn, Estall, Ferdaoussi, Fullerton, Hull-Meichle, Pepper, Korbutt, Levings, Lim, Mulvihill, Rabasa-Lhoret, Riddell, Rutter, Tsai, Woo and Verchere! 📝
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Gareth Lim @glim2016.bsky.social · 27/01/2026
Are you soon-to-be PhD student or postdoctoral fellow, based outside of Canada? Here is a great program for you if you are interested in diabetes and/or obesity research! PhD students- $40k CAD/year; three years PDFs- $70k CAD/year; two years Let's chat! nserc-crsng.canada.ca/en/canada-im...
nserc-crsng.canada.ca
Canada Impact+ Research Training Awards: Q&A
As announced in Budget 2025 - Canada Strong, a resilient Canadian economy depends on a highly skilled workforce.
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Sarah Crome @sarahcrome.bsky.social · 22/01/2026
The new Crome Lab at BC Cancer is up and running — and we’re hiring! We’re recruiting a PDF for a newly funded project on ILCs & NK cells in Type 1 Diabetes, using spatial genomics and single-cell approaches. 🔗 jobs.phsa.ca/job/postdoct... #Immunology #SingleCell #SpatialGenomics #Type1Diabetes
jobs.phsa.ca
Postdoctoral Fellow - Innate Lymphoid Cells and Spatial Genomics in Type 1 Diabetes, Crome Lab, Terry Fox Laboratory - BC Cancer Vancouver | Working at Provincial Health Services Authority | Careers a...
Postdoctoral Fellow - Innate Lymphoid Cells and Spatial Genomics in Type 1 Diabetes, Crome Lab, Terry Fox Laboratory BC Cancer Vancouver, BC We are recruiting a highly motivated Postdoctoral Fellow to...
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Lara Green @laragreen.bsky.social · 05/01/2026
I'm excited to share that we are hiring two positions with Breakthrough T1D (formerly JDRF) Canada! National Specialist, Research & Mental Health (Bilingual) National Manager, Medical Affairs Please pass these along to anyone who may be interested: jobs-ca.silkroad.com/breakthrough...
jobs-ca.silkroad.com
Recent Job Search - Breakthrough T1D
Find a career with Breakthrough T1D
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CIRTN-R2FIC @cirtn.bsky.social · 25/11/2025
CIRTN-R2FIC is currently running in Toronto its 4th Annual Meeting. During this meeting we have launched our mini interview series called "Islets in a Pod" ! Our first interview is with Dr. Patrick MacDonald from the University of Alberta. youtu.be/UlHn_1Fz3ck?...
youtu.be
#1 Islets in a Pod with Dr. Patrick MacDonald
YouTube video by CIRTN-R2FIC
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Banting & Best Diabetes Centre @bbdc-uoft.bsky.social · 06/11/2025
🌟 New opportunity - Fourteen summer studentships are available for undergraduate and med students to carry out summer research in diabetes under the supervision of a member of the BBDC. Learn more! bbdc.org/funding/fund...
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Amanda Oakie @aoakie.bsky.social · 05/11/2025
Congratulations, Cristina, well deserved!
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Research at UHN @uhnresearch.ca · 05/11/2025
Congratulations to Dr. Cristina Nostro from @uhn.ca’s McEwen Stem Cell Institute on winning the prestigious 2025 Till & McCulloch Award! 🎉 Her impactful research in #diabetes and #RegenerativeMedicine brings us closer to #AHealthierWorld every day. 🔗 Read more: www.uhnresearch.ca/news/honouri...
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Stem Cell Network @stemcellnetwork.ca · 30/10/2025
(1/2) 🇨🇦 Canada changed the world with the discovery of insulin — and 40 years later, with #StemCells, launched #RegenerativeMedicine. Today, another breakthrough is within reach.
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Stem Cell Network @stemcellnetwork.ca · 27/10/2025
📢 Exciting job opportunity! The Epelman Lab at University Health Network is hiring a Postdoctoral Researcher in #Cardiology to study engineered heart tissue, tissue regeneration, and macrophage biology. 🫀 Learn more and apply! ➡️ stemcellnetwork.ca/career-oppor...
Postdoctoral Researcher
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Stem Cell Network @stemcellnetwork.ca · 14/10/2025
📢 McGill University is hiring! A tenure-track Assistant Professor position is open in Pluripotent Stem Cells in Regenerative Medicine, within the Department of Pharmacology and Therapeutics, in partnership with the Meakins-Christie Labs at the RI-MUHC. Apply. ➡️ stemcellnetwork.ca/wp-content/u...
Assistant Professor (Tenure-Track)
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Patrick MacDonald🇨🇦 @bcellorg.bsky.social · 30/09/2025
Yesterday we celebrated our 600th human research islet isolation in support of diabetes research (and then last night isolated the islets in the pic). I’m very fortunate to work with such a dedicated team! See more at www.isletcore.ca
CakeCelebrating 600Islets for research
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Elizabeth Rideout @ejrideout.bsky.social · 20/09/2025
I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.
cell.com
Insulin/insulin-like growth factor signaling pathway promotes higher fat storage in Drosophila females
Biswas et al. show that greater dietary sugar intake promotes fat accumulation in Drosophila adult females. In the presence of dietary sugar, the activity of the conserved insulin/insulin-like growth ...
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Rebecca Hull-Meichle @rlhull-meichle.bsky.social · 18/09/2025
Save the date for the 2026 A-BC Islet Biology meeting! Looking forward to many fantastic presentations by trainees in islet biology from all over Canada as well as great keynote lectures. Please share widely! isletmeeting.weebly.com
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Daniel Durocher @durocher1.bsky.social · 28/08/2025
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!
Image of Toronto
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Banting & Best Diabetes Centre @bbdc-uoft.bsky.social · 13/08/2025
Discover MyRoad, a platform dedicated to research training and mentorship in the fields of obesity, diabetes, and cardiometabolic diseases. New opportunities are available this fall, including cohort-based training, travel awards, and health research exchange competitions. www.myroadplatform.ca/en
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Novo Nordisk Network for Healthy Populations @nhp-uoft.bsky.social · 06/08/2025
The @calvin-ke.bsky.social lab is hiring a Postdoctoral Fellow! Apply to join the team, where you will lead community-engaged, equity-focused type 2 diabetes research (qualitative & mixed-methods). jobs.smartrecruiters.com/UniversityHe...
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Yassi Aghazadeh @yassiag.bsky.social · 04/08/2025
Very proud to share the first review from the lab with contributions of all lab members. Writing this gave our new lab opportunity to read and discuss many papers and grow as a team. www.frontiersin.org/journals/imm...
frontiersin.org
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Amanda Oakie @aoakie.bsky.social · 25/07/2025
👇👇👇
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Daniel Drucker @danieljdrucker.bsky.social · 15/07/2025
A regulated pathway through which glucagon modulates insulin release via alpha to beta cell communication and control of GLP-1R internalization and beta cell Ca2+ responses to high glucose @cp-cellmetabolism.bsky.social @daveyboyhod.bsky.social #islets www.cell.com/cell-metabol...
cell.com
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication
Tong et al. utilize advanced imaging approaches to reveal that beta cells located next to alpha cells are specially adapted as glucagon sensors by virtue of their high expression levels of GLP1R. Thes...
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Stem Cell Network @stemcellnetwork.ca · 11/07/2025
📣 Exciting opportunity! The McEwen Stem Cell Institute at @uhnresearch.ca is hiring a Postdoc Researcher to join the Protze Lab. The project focuses on #HumanPluripotent stem cell-derived AVNLPCs and their application as a biological conduction bridge. 🔗 jobs.smartrecruiters.com/UniversityHe...
Postdoctoral Researcher
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Patrick MacDonald🇨🇦 @bcellorg.bsky.social · 08/07/2025
We are launching a new initiative to support experimental design, data management/analysis and bioinformatics. Early days yet, but check it out here. www.bcell.org/adi-datasci....
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 07/07/2025
Come join us in Vancouver! Exciting opportunity for a more senior investigator researching new regenerative medicine approaches for Type 1 diabetes. $8M in funding for successful candidate research.ubc.ca/media/file/j...
research.ubc.ca
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Yassi Aghazadeh @yassiag.bsky.social · 27/06/2025
Very excited about our project aiming at advancing cell therapies for type 1 diabetes. and very thankful for receiving funding from @stemcellnetwork.ca
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Patrick MacDonald🇨🇦 @bcellorg.bsky.social · 25/06/2025
Review on metabolism in stem cell derived beta cells from former PhD student with us, Frank Lin. Cell Reports @cp-cellreports.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Glucose metabolism and regulation in establishing human stem cell-derived β cell maturation
Efforts to generate mature stem cell-derived β (SC-β) cells have been ongoing for decades, yet their functional performance still falls short of prima…
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Gareth Lim @glim2016.bsky.social · 28/05/2025
There is still a spot for a PhD student or Postdoc in the Lim Lab! If you are interested in metabolism, 14-3-3 proteins, adipocytes, or beta-cells, please email me (details at www.limlab.ca). International applicants are welcome! Positions are fully funded. Looking forward to working with you!
limlab.ca
Lim Lab
Exploring how 14-3-3 proteins contribute to metabolism and metabolic diseases
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Amanda Oakie @aoakie.bsky.social · 26/05/2025
Congrats to @sarahcolpitts.bsky.social and the @sarahcrome.bsky.social lab! Check out the effects of ILC-islet co-tx below 👇👇
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Amanda Oakie @aoakie.bsky.social · 20/05/2025
Neat discussion below! 👇👇
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Harnessing Pluripotency @pluripotency.bsky.social · 20/05/2025
📣 NEW PAPER ALERT! 🧵 I love kidney organoids - tiny nephron clusters grown in the lab from pluripotent stem cells. But can they treat kidney disease? New data suggests they can (in mice)! Let's dive in ⬇️ tinyurl.com/mr3sd6vu #KidneyOrganoids #CellTherapy #ChronicKidneyDisease #AcuteKidneyInjury
tinyurl.com
Human iPSC–derived nephron progenitor cells treat acute kidney injury and chronic kidney disease in mouse models
Expanded human iPSC–derived nephron progenitor cells secrete renoprotective factors that have therapeutic potential for AKI and CKD.
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Dr Peter Senior @islettx.bsky.social · 15/05/2025
Excited to enroll our first participant for testing an agent (tolimidone) we hope will promote beta cell regeneration, building on preclinical work from Dr Jean Buteau at @albertadiabetes.bsky.social. Supported by Alberta Diabetes Foundation & biodexa pharmaceuticals www.ualberta.ca/en/folio/202...
ualberta.ca
Could a pill cure diabetes? A U of A researcher is working on it
A simple pill to treat or even cure diabetes could be possible, thanks to University of Alberta research — and funding that is laying vital groundwork.
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 13/05/2025
Is ELISA success correlated with strength with which plate is banged when washing?
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 29/04/2025
Thrilled to share our latest work, which was the outstanding doctoral work of @samanthajsyoon.bsky.social academic.oup.com/endo/advance... 1/12
academic.oup.com
NPAS4 depletion in POMC neurons protects from obesity and alters the feeding-regulated transcriptome in male mice
Abstract. Immediate Early Genes (IEGs), such as Neuronal PAS domain protein 4 (Npas4), are induced as part of the response to environmental stimuli. In the
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Daniel Drucker @danieljdrucker.bsky.social · 17/04/2025
New data from Gary Lewis and colleagues @uhnresearch.bsky.social interrogating how GLP-2 modulates chylomicron secretion in rats via VEGFR3 and MLC2 www.ghadvances.org/article/S277...
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Daniel Drucker @danieljdrucker.bsky.social · 18/03/2025
@elaineywchen.bsky.social www.statnews.com/2025/03/17/t...
statnews.com
NIH cancels funding for landmark diabetes study at a time of focus on chronic disease
The Trump administration has canceled funding for an ongoing 30-year, nationwide study tracking patients with prediabetes and diabetes, researchers said.
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Mathieu Ferron @mathieuferron.bsky.social · 18/03/2025
Tenure track position in pharmacology or toxicology at McGill, in Montreal!!! www.nature.com/naturecareer...
nature.com
Assistant / Associate Professor (Tenure Track), Department of Pharmacology and Therapeutics - Montréal, Quebec (CA) job with McGill University | 12837963
Faculty of Medicine and Health Sciences – Department of Pharmacology and Therapeutics, Toxicology (L000054
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Dr Peter Senior @islettx.bsky.social · 13/03/2025
Come and work with us at the Alberta Diabetes Institute. We are connecting people with T1D and researchers to accelerate innovation to improve the lives of people with diabetes. We need a project lead to help us. apps.ualberta.ca/careers/post...
apps.ualberta.ca
Project Lead - Careers@UAlberta.ca
University of Alberta: Careers@UAlberta.ca
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 10/03/2025
We're looking for postdoctoral scholars to join our team in Vancouver 🇨🇦. We work on cell-based approaches aimed at curing type 1 diabetes. Bring your own ideas for projects or work on one that's already funded! More details here: www.nature.com/naturecareer...
nature.com
Postdoctoral Research Fellow - Vancouver, British Columbia (CA) job with University of British Columbia Department of Surgery | 12837375
The successful candidate will work on a project developing cell-based therapies for those living with type 1 diabetes (T1D).
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Mathieu Ferron @mathieuferron.bsky.social · 03/03/2025
Opening at UdeM Biochemistry department for a professor position in bioinfomatics! www.umontreal.ca/public/www/d...
umontreal.ca
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