Reposted by Harnessing Pluripotency
Excited to share our new paper in Nat Comms on how human stem cell-derived pancreatic progenitors choose between islet and enterochromaffin (EC)-like fates - and how we can steer that choice! A story in a few tweets…
Full paper 👉 doi.org/10.1038/s414...
doi.org
Efficient control of enterochromaffin versus islet differentiation from human pluripotent stem cell-derived pancreatic progenitors - Nature Communications
How different islet lineages emerge within pancreatic islets remains largely unknown. Here, using hPSC and mouse models, the authors identify mechanisms that influence islet versus enterochromaffin li...
