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Alexandria Miller

@alexmsci.bsky.social
252 followers 198 following 19 posts

Assistant Professor at the University of Iowa studying ion channels and other membrane proteins in 🦠 | Previously at HHMI Janelia and MSK Cancer Center | Avid 🥾 and 🎻.

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Reposted by Alexandria Miller
University of Iowa Molecular Physiology and Biophysics @uiowaphysiology.bsky.social · 23/07/2026
What’s better than one major NIH award? Two! 🎉 Congratulations to @alexmsci.bsky.social and her lab on receiving an R01 from the National Institute of Allergy and Infectious Diseases for her project, “Decoding the Structure, Function and Pharmacology of TOK Channels from Human-Pathogenic Fungi.”
Miller lab team in lab
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Alexandria Miller @alexmsci.bsky.social · 28/04/2026
www.linkedin.com/posts/alexan...
linkedin.com
We are excited to share the first structure of a potassium channel from fungi, TOK1 from Candida albicans, a major human fungal pathogen, and it's a weird one! The first four helices form a… | Al...
We are excited to share the first structure of a potassium channel from fungi, TOK1 from Candida albicans, a major human fungal pathogen, and it's a weird one! The first four helices form a tetraspan...
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Alexandria Miller @alexmsci.bsky.social · 16/12/2025
Chowdhury and Miller labs … On Ice!
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Reposted by Alexandria Miller
Andrew Plested @andrewplested.bsky.social · 02/12/2025
What fantastic news. What a coup by the Charité! HIV remission!!! From basic science. Incredible what people are doing in Berlin. Yet we suffer under absurd short-sighted cuts whilst Bayern and others are expanding their science. People don't seem to realise it has taken decades to build this up.
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Alexandria Miller @alexmsci.bsky.social · 19/11/2025
www.nytimes.com/2025/11/18/c...
nytimes.com
Iowa City Made Its Buses Free. Traffic Cleared, and So Did the Air.
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Alexandria Miller @alexmsci.bsky.social · 02/11/2025
Fall is here in Eastern Iowa :)
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Alexandria Miller @alexmsci.bsky.social · 18/10/2025
www.cell.com/cell/abstrac...
cell.com
De novo designed voltage-gated anion channels suppress neuron firing
This study reports the successful de novo design of voltage-gated anion channels that are distinct from native channels. They exhibit voltage-dependent ion conductance and are capable of being tuned f...
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Alexandria Miller @alexmsci.bsky.social · 16/10/2025
Whoa, this is big…
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Reposted by Alexandria Miller
Jeremy Berg @jeremymberg.bsky.social · 24/08/2025
New York Times story with profiles of researchers whose grants were terminated. [Gift Link] www.nytimes.com/2025/08/24/o...
nytimes.com
Opinion | America First? Not When It Comes to Your Health.
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Reposted by Alexandria Miller
Nicholas Schnicker @nschnick.bsky.social · 06/05/2025
Happy to share we got the NoA for the NIH S10 proposal I submitted for a Glacios #cryoEM 🔬 for #IowaResearch #structuralbiology
NIH award notice
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Alexandria Miller @alexmsci.bsky.social · 11/04/2025
Scientists are “not opposed to examining how taxpayer funds are used; on the contrary, we welcome efforts to improve efficiency […]. But what’s happening now has nothing to do with efficiency. These actions […] are indiscriminate and risk doing real, long-lasting harm.” www.cnn.com/2025/04/09/h...
cnn.com
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
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Alexandria Miller @alexmsci.bsky.social · 17/03/2025
Irrespective of your opinion on the matter, I think this is an important read to understand why some of the mistrust in science exists in our society today.
nytimes.com
Opinion | We Were Badly Misled About the Event That Changed Our Lives
Five years after the start of Covid, we still don’t know the truth.
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Alexandria Miller @alexmsci.bsky.social · 13/03/2025
www.forbes.com/sites/michae...
forbes.com
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
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Reposted by Alexandria Miller
Brandy Zadrozny @brandyzadrozny.bsky.social · 26/02/2025
First measles death in a decade. www.nbcnews.com/health/healt...
nbcnews.com
A person dies of measles in West Texas outbreak
At least 124 cases have been reported in Texas, with at least 18 hospitalizations. Most are children.
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Reposted by Alexandria Miller
Jeremy Berg @jeremymberg.bsky.social · 21/02/2025
New York Times article now up on Federal Register stuff. www.nytimes.com/2025/02/21/s... 1/n
nytimes.com
Trump Administration Stalls Scientific Research Despite Court Ruling (Gift Article)
Using an arcane law, officials have effectively delayed funding from the National Institutes of Health, leaving medical studies in jeopardy.
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Reposted by Alexandria Miller
Channels, Receptors & Transporters Subgroup of BPS @bpscrt.bsky.social · 19/01/2025
The Channels, Receptors & Transporters Subgroup of the @biophysicalsoc.bsky.social is excited to announce the final program for our 2025 Symposium. Please join us on Feb 15 to hear from @willowcoyote.bsky.social @drcontrexin.bsky.social @corrylab.bsky.social and others 👇Thanks to our sponsors!
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Reposted by Alexandria Miller
Max Planck Institute of Biophysics @mpibp.bsky.social · 17/01/2025
Fresh out of the press! ✨Check out our new paper on the violent entry of the HIV capsid into the nuclear pore — and how it cracks the gate! 🤯 💥 Incredible work from @becklab.bsky.social and @hummerlab.bsky.social 🤩 More here: www.biophys.mpg.de/2842024/hivcapsid-cracks-the-npc?c=2011019 🔗 #teamTOMO
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Reposted by Alexandria Miller
Leading Edge Fellows Program @leadingedgeprogram.bsky.social · 06/01/2025
Leading Edge is celebrating a milestone: 100 (actually 102!) new assistant professors!!! 🎉🥳🎊 Learn more about them: www.leadingedgesymposium.org/fellows/ Applications are now open for the 2025 Leading Edge cohort! (Deadline Feb 3). You do NOT need to be ready for the job market to apply.
Headshots of 102 women and non-binary scientists who are now assistant professors. At the bottom is the Leading Edge logo and www.leadingedgesymposium.org
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Alexandria Miller @alexmsci.bsky.social · 16/01/2025
I had missed this. Looks to be the more interesting paper on the topic in a while. Using electric-field-stimulated time-resolved X-ray crystallography to investigate K ion movement across the selectivity filter in the well-studied “NaK2K” channel www.sciencedirect.com/science/arti...
sciencedirect.com
Direct visualization of electric-field-stimulated ion conduction in a potassium channel
Understanding protein function would be facilitated by direct, real-time observation of chemical kinetics in the atomic structure. The selectivity fil…
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Reposted by Alexandria Miller
Nurunisa @nneyzi.bsky.social · 07/01/2025
MYO7A, linked to Usher syndrome 1B, is known to localize key bundle proteins - but is this the motor protein responsible for tensioning hair cell tip links? Using a mouse line that enables late, conditional deletion of MYO7A, this work establishes that it is not- shifting focus back to MYO1C.
pnas.org
MYO7A is required for the functional integrity of the mechanoelectrical transduction complex in hair cells of the adult cochlea | PNAS
Myosin-VIIA (MYO7A) is an unconventional myosin responsible for syndromic (Usher 1B) or nonsyndromic forms of deafness in humans when mutated. In t...
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Reposted by Alexandria Miller
Ben Engel @cellarchlab.com · 06/01/2025
Towards community-driven visual proteomics! Excited to finally share this large-scale curated & annotated dataset of 1829 high-quality #cryoET tomograms of the little green alga that just keeps giving— Chlamydomonas! 🧪🧶🧬🌾🌊🌍 Preprint📜: www.biorxiv.org/content/10.1... A short thread🧵👇
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Alexandria Miller @alexmsci.bsky.social · 04/01/2025
De novo design of a voltage gated anion channel. www.biorxiv.org/content/10.1...
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Alexandria Miller @alexmsci.bsky.social · 02/01/2025
This is clever 👇
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Alexandria Miller @alexmsci.bsky.social · 24/12/2024
My amazing lab went bowling and shared a meal together a couple of weeks ago to celebrate the holidays. And there were soo many treats…Happy holidays to everyone!
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Reposted by Alexandria Miller
Janelia Research Campus @hhmijanelia.bsky.social · 19/12/2024
🦠A team led by the Lippincott-Schwartz Lab used a new technique developed at Janelia called high-resolution template matching, or HRTM, to uncover in unprecedented detail the movement of ribosomes – the molecular structures that synthesize proteins inside cells. 🔗 hhmi.news/401LKMq
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Reposted by Alexandria Miller
Science Magazine @science.org · 12/12/2024
Science’s 2024 Breakthrough of the Year is lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months. Learn more about this year's #BOTY and other big advances in science: scim.ag/3BrCtUn
Science’s 2024 Breakthrough of the Year is lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months. The drug attaches to the lattice-like capsid proteins that shield the virus’s genetic material—a mechanism that could inspire other antivirals. Lenacapavir could help end the HIV/AIDS epidemic, but that will hinge on access for those who need it most.
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Ardem Patapoutian @ardemp.bskyverified.social · 13/12/2024
I wasn’t sure about the new HHMI initiative at first, but learning that just 10 institutions—led by Stanford, Berkeley, and Rockefeller—account for over half of HHMI’s investigators puts things into perspective. Efforts to improve this aren’t a bad idea! www.statnews.com/2024/12/13/h...
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Reposted by Alexandria Miller
Oli Clarke @olibclarke.bsky.social · 10/12/2024
Filing under TIL... the PDBj mirror of EMPIAR automatically compresses compressible movies (MRC stacks) - meaning in this case only 600GB to download rather than 5.5TB! 😱
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Reposted by Alexandria Miller
Jon Grimm @dyerfulchymist.bsky.social · 03/12/2024
In honor of our annual ChemisTree event @hhmi.bsky.social @hhmijanelia.bsky.social today, here's a repost of a little video I made a few years back to demonstrate how the ornament silver plating works! #chemsky
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Janelia Research Campus @hhmijanelia.bsky.social · 04/12/2024
🎉Congratulations to Luke Lavis (@rhodamine110.bsky.social), recipient of the 2025 Gregorio Weber Award for Excellence in Fluorescence Theory and Applications from ISS for his pioneering work on the design & synthesis of small-molecule fluorescent dyes.🧪
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Reposted by Alexandria Miller
Willow Coyote-Maestas @willowcoyote.bsky.social · 04/12/2024
We are now accepting applications for speakers from Native American trainees - if you know of someone who would be a good fit, encourage them to apply! More info in the original thread Apply to be speaker at Full Circle here: forms.gle/dMUtGWvigrNA... PS: We have travel funds available! Plz share!
forms.gle
Google Forms: Sign-in
Access Google Forms with a personal Google account or Google Workspace account (for business use).
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Reposted by Alexandria Miller
Leading Edge Fellows Program @leadingedgeprogram.bsky.social · 10/11/2024
If you want to follow awesome women and non-binary early career scientists, the starter pack of Leading Edge Fellows is here! go.bsky.app/He3EAcq
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Reposted by Alexandria Miller
HHMI @hhmi-science.bsky.social · 20/11/2024
🎉 Congratulations to Vivek Jayaraman and Gaby Maimon, co-recipients of the 2024 W. Alden Spencer Award from Columbia University Vagelos College of Physicians and Surgeons for their pioneering contributions in elucidating the neural circuits underlying navigation in fruit flies.
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Alexandria Miller @alexmsci.bsky.social · 22/11/2024
Past and present unite. Quick trip to Janelia with my postdoc, Gufran Siddiqui. Was great to catch up with David Clapham and many others.
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