In this talk, I will show how combining phylogenetic inference, protein structure prediction, and ancestral sequence reconstruction opens new ways to investigate how protein functions originate and di...

Here, the authors show that 2’-O-methylated RNA fragments from ribosomal RNA naturally block TLR7 and TLR8, helping to avoid avoid harmful self-RNA detection and autoimmunity.

Throughout my PhD, I determined the transport mechanisms of two proteins that we show break the standard channel / transporter definitions and instead function as anion “chansporters” - proteins that exist somewhere on the spectrum between transporters and channels.

Tao and Corry investigate how the binding of sodium channel inhibitors to the Nav1.5 pore using simulations reveal promiscuous, polyspecific binding at the

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The Australian Universities Accord offers a roadmap for reform, but there are major challenges ahead.