Recent work from the Degron Tagging Cluster Wood laboratory addresses an important question in the targeted protein degradation field: does the mechanism by which an oncogene become overactive influence how effectively the target protein can be eliminated?
nmgn.mrc.ukri.org/news/how-can...
nmgn.mrc.ukri.org
How cancer genes are activated shapes the effectiveness of next-generation protein-degrading drugs | National Mouse Genetics Network
A new study from the Degron Tagging Cluster Wood laboratory at the University of Edinburgh addresses an important but underexplored question in the targeted protein degradation field: does the mechani...