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MRC MitoCluster

@mrcmitocluster.bsky.social
185 followers 183 following 14 posts

Research cluster working with @MRCHarwell.bsky.social as part of @MRCMouseNetwork.bsky.social studying mitochondria using #MouseModels nmgn.mrc.ukri.org

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MRC MitoCluster @mrcmitocluster.bsky.social · 24/09/2026
The MitoCluster team was well represented at the @mrcmousenetwork.bsky.social Science Meeting in York this week w several presentations from PIs & ECRs - well done! @uclqsion.bsky.social @mrc-mbu.bsky.social @mrcharwell.bsky.social @robpitceathly.bsky.social @jellevda.bsky.social
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London Mitochondrial Centre @londonmito.bsky.social · 01/06/2026
We are delighted to share a new open-access study by Dr Micol Falabella & colleagues, published in @natcomms.nature.com Nature Communications: "COXFA4L2 upregulation preserves residual cytochrome c oxidase activity in COXFA4-related Leigh-like encephalopathy" Paper: www.nature.com/articles/s41...
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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 30/04/2026
#Training: Our new 2-day Using Conditional Transgenic Models course is designed for anyone using or planning to use conditional models and will equip trainees with a clear understanding of how these models function biologically, as well as the practical ways in which they can fail. Join us in June:
har.mrc.ac.uk
Using Conditional Transgenic Models | Mary Lyon Centre
Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!
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MRC MitoCluster @mrcmitocluster.bsky.social · 12/05/2026
Catch up on the session "Introduction to Mitochondrial Diseases & Where We Are with Models" delivered by MitoCluster at Queen Square Advances in Mitochondrial Medicine 2026. Link to online recording available via the London Mitochondrial Centre.
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 07/05/2026
Excited to share results from the first Business Engagement Fund from the MRC, supporting #academia-#industry collaboration. Work from Nick Greene and Outfox Bio shows LNP-mRNA delivery works effectively in an NKH mouse model—proof of concept for therapeutic mRNA. nmgn.mrc.ukri.org/news/a-busin...
nmgn.mrc.ukri.org
A Business Engagement Fund project to test Lipid Nanoparticle (LNP)-mediated mRNA delivery and efficacy | National Mouse Genetics Network
The Medical Research Council provided £750K in funding for the National Mouse Genetics Network’s Business Engagement Fund with a call for applications in early 2023. The Business Engagement Fund suppo...
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London Mitochondrial Centre @londonmito.bsky.social · 23/04/2026
Looking forward to seeing you soon at Queen Square Advances in Mitochondrial Medicine 2026! We hope you'll join us for the day, plus the networking reception after (drinks and snacks provided). UCL/UCLH staff & students - contact us via email for your free registration code: bit.ly/QSmitomed2026
bit.ly
Queen Square Advances in Mitochondrial Medicine 2026
The London Mitochondrial Centre is hosting a one-day symposium.
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MRC MitoCluster @mrcmitocluster.bsky.social · 31/03/2026
Interested in Pre-clinical Mitochondrial Disease Models? MRC MitoCluster is delivering a session this May at Queen Square Advances in Mitochondrial Medicine 2026. Register now to join! #MitochondrialDisease #MitochondrialMedicine #mtDNA #GeneticEngineering #PreclinicalResearch #RareDisease
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 23/03/2026
Stealth BioTherapeutics has today announced an award from our Business Engagement Fund to support a new collaboration to evaluate the effects of their compound SBT-589 on biomarkers of disease in a mouse model of Leigh syndrome, a rare mitochondrial disorder: nmgn.mrc.ukri.org/news/busines...
nmgn.mrc.ukri.org
Business Engagement Fund award to support mitochondrial disease research | National Mouse Genetics Network
Stealth BioTherapeutics, a commercial-stage biotechnology company focused on the discovery, development, and commercialisation of novel therapies for diseases involving mitochondrial dysfunction, have...
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Cambridge Clinical Mitochondrial Research Group @mitocamb.bsky.social · 25/02/2026
#mito @mrc-mbu.bsky.social @taylorlabncl.bsky.social @londonmito.bsky.social @mitonewcastle.bsky.social
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 10/02/2026
Our Best Models Working Group can offer advice on the use of a range of model systems. The next in our series of #MeetTheExpert posts features Laura Greaves, whose group investigates the role of age-related mitochondrial DNA mutations in cancer biology nmgn.mrc.ukri.org/working-grou...
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MRC MitoCluster @mrcmitocluster.bsky.social · 14/11/2025
Great two days in York with the MRC National Mouse Genetics Network. Always a pleasure to be invited to share MitoCluster's work, thank you! @mrcmousenetwork.bsky.social @jellevda.bsky.social @lauragreaves.bsky.social @robpitceathly.bsky.social
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 04/11/2025
Our Best Models Working Group can offer advice on the use of a range of model systems. Over the coming weeks, we will be highlighting the diverse expertise of our Working Group, starting with Julia Cordero, an expert in the use of Drosophila to study intestinal biology. #MeetTheExpert
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MRC MitoCluster @mrcmitocluster.bsky.social · 10/11/2025
📢 PhD Opportunity with Dr Christopher Carroll at City St George's School of Health & Medical Science, "Advancing genotype-phenotype correlations with Multiplex Assays of Variant Effect". Read more: mrc-lid.lshtm.ac.uk/2026-27-proj... Apply: mrc-lid.lshtm.ac.uk/apply/
mrc-lid.lshtm.ac.uk
2026-27 Project (Carroll & Pittman) - MRC London Intercollegiate Doctoral Training Partnership Studentships
Advancing genotype-phenotype correlations with Multiplex Assays of Variant Effect SUPERVISORY TEAM Supervisor Dr Christopher Carroll...
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London Mitochondrial Centre @londonmito.bsky.social · 21/10/2025
✍️ Apply now! Clinical Fellowship in imaging for evaluation of mitochondrial disease severity, progression, and treatment response, in our excellent & supportive team at UCL Queen Square / UCLH NHS Highly Specialised Service for Rare Mitochondrial Disorders shorturl.at/jaSke
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 30/09/2025
#Training: Our new Laboratory Skills for Animal Technicians course is for #technicians who would like to develop their lab skills, including processing blood samples, dose calculations, and use of standard equipment. Join us in February: www.har.mrc.ac.uk/training/cou...
har.mrc.ac.uk
Laboratory Skills for Animal Technicians | Mary Lyon Centre
Having the knowledge and confidence to work safely in the laboratory is a valuable skill for all animal technicians. This course will cover basic theoretical and practical laboratory skills including following COSHH risk assessments, best laboratory practice, use of fume hoods/biosafety cabinets, centrifuges and other laboratory equipment, pipetting skills, using balances and preparing reagents and […]
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 25/09/2025
Our first session of today's #OrganoidsAreUs2025 is dedicated to organoid models in cancer research. We go with ✨ Vincenzo Corbo ✨ Ben Dwyer ✨ Maximilian Reichert ✨ Chiara Braconi Another packed session for a critical and fast-developing field!
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 24/09/2025
Second session on #StemCells #regeneration and #cancer. We start with 🧪 Phil Jones from the @sangerinstitute.bsky.social 🧪 Followed by Suet Yu Leung from Hong Kong Uni and 🧪 Eleanor Earp from @edinburghuni.bsky.social , ✨ First keynote lecture by Helmuth Gehart from @ethz.ch #OrganoidsAreUs2025
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 23/09/2025
Opening session sponsored by @stemcell.com and OLS with a welcome from Director Owen Sansom @cruk-si.bsky.social and Elizabeth Vincan @unimelb.bsky.social . Our plenary speaker Prof Hans Clevers from @utrechtuniversity.bsky.social talks about human epithelial organoids. #OrganoidsAreUs2025
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 23/09/2025
We are ready to go at the CRUK Scotland Institute, @cruk-si.bsky.social, for this exciting meeting, bringing together a huge wealth of new technologies and scientific advances. First session this afternoon. Watch this space! #OrganoidsAreUs2025
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London Mitochondrial Centre @londonmito.bsky.social · 19/09/2025
It's World Mitochondrial Disease Awareness Week 💚 Since we couldn't #LightUpForMito this year the team's looking lit in green to raise awareness instead! Read more here: www.thelilyfoundation.org.uk/charity/get-... #mitoaware #mitochondrialdisease #worldmitoweek2025 @lilyfoundation.bsky.social
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 16/09/2025
On 14th November, we are once again holding our Network Science Day in York, which is an exciting opportunity for Network members and non-members to engage and develop new collaborations! The meeting is free to attend. Find out more and register by emailing us at Genetics_Network@har.mrc.ac.uk.
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London Mitochondrial Centre @londonmito.bsky.social · 22/07/2025
Looking for a Clinical Research Fellow to join our team! Please share and apply below by 7th August 👇
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 17/07/2025
Join us for Organoids Are Us 2025, a symposium featuring organoids, stem cells, cancer, inflammatory disorders and infectious disease. 📆23 - 26 September 2025 📍Glasgow, Scotland Early bird registration extended to 18th July. Register below! 👇 www.crukscotlandinstitute.ac.uk/events/organ...
crukscotlandinstitute.ac.uk
Organoids Are Us 2025
Further information about this event including our invited speakers and conference programme are available in the tabs below. If you have any questions, please contact organoids-are-us@crukscotlandinstitute.ac.uk
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Alex Whitworth lab @labwhitworth.bsky.social · 16/07/2025
Delighted to share our latest work looking at the role of the RNA-binding proteins Clu1 (yeast)/Clu (flies) in regulating the translation of #mitochondria proteins. Really interesting regulator of mito biology. Huge, long-running effort by PDRA Leonor Miller-Fleming 👏 dx.plos.org/10.1371/jour...
dx.plos.org
Clu1/Clu form mitochondria-associated granules upon metabolic transitions and regulate mitochondrial protein translation via ribosome interactions
Author summary Mitochondria are essential cellular organelles that perform many important roles in regulating metabolism. They are dynamic in form, function and composition which is crucial to maintai...
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Newcastle Mitochondrial Research Group @mitonewcastle.bsky.social · 26/06/2025
📢 Exciting 3-year funded PhD opportunity 🧠 Prof Bobby McFarland and Dr Laura Smith are advertising for a PhD student to join their lab at the Newcastle Mitochondrial Research Group. 📅 Closing date: 16th July 2025 ⏰ Start date: 15th September 2025 To apply: www.findaphd.com/phds/project...
findaphd.com
PhD studentship - Understanding the causes and identifying treatments for Alpers’ syndrome at Newcastle University on FindAPhD.com
PhD Project - PhD studentship - Understanding the causes and identifying treatments for Alpers’ syndrome at Newcastle University, listed on FindAPhD.com
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The Lily Foundation @lilyfoundation.bsky.social · 16/07/2025
10 years ago, The Lily Foundation stood at the heart of the campaign to legalise #mitochondrialdonation. Today, research confirms it’s working, giving families the chance to have healthy, genetically related children 💗 Read more and please share! www.thelilyfoundation.org.uk/news/breakth...
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Newcastle University @newcastleuni.bsky.social · 17/07/2025
We're proud to announce our work developing a ground-breaking mitochondrial donation IVF treatment has now seen eight healthy babies born 👶 Find out more 👇 www.ncl.ac.uk/press/articl... #WeAreNCL #Health #News #Mitochondria
ncl.ac.uk
Eight babies born after Mitochondrial donation
The UK’s pioneering licensed IVF technique to reduce the risk of mitochondrial diseases carried out in Newcastle has seen eight babies born, published research shows.
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Cambridge Clinical Mitochondrial Research Group @mitocamb.bsky.social · 07/05/2025
We spent a great afternoon at the House of Lords for the launch of the @lifearc.bsky.social Centre for #Rare #Mitochondrial Diseases, supported by @mdukcharity.bsky.social The event centre hosted staff, dignitaries, patients, MPs & those involved in rare disease policy & research. We even unveiled…
Plaque showing that we are proudly part of the LifeArc Centre for Rare Mitochondrial Diseases, with funding from MDUK
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Minczuk Lab @mitogene.bsky.social · 06/05/2025
Last chance to join us for the Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair, June 1 - 5, 2025 | Nashville, Tennessee @faseborg.bsky.social
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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 29/04/2025
#Training: Our Mouse Genetics and Colony Management for Animal Technologists course introduces animal technicians and ECRs to the background of mouse genetics, genetic crosses, and calculations of breeding numbers. Book a place on our July course now www.har.mrc.ac.uk/training/cou...
har.mrc.ac.uk
Mouse Genetics and Colony Management for Animal Technologists
This course covers topics such as Mendelian gene inheritance and genetic crosses, as well as important colony management aspects
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Prof Anthony Isles @profantisles.bsky.social · 29/04/2025
Fantastic symposium at #BNA2025 @britishneuro.bsky.social highlighting the work the MRC National Mouse Genetics Network and friends! @mrcmousenetwork.bsky.social
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MRC MitoCluster @mrcmitocluster.bsky.social · 15/04/2025
Very full schedule at our #IMGCglasgow workshop last week, delivered by MitoCluster team @robpitceathly.bsky.social, Carlo Viscomi, @mitogene.bsky.social, and @jim-ca.bsky.social. A pleasure to attend, thanks for the invite @mrcmousenetwork.bsky.social & IMGS! 🧬 #mitochondria #MouseModels #ECR
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 07/04/2025
Kicking off the main sessions today with a welcome from IMGS president Yan Herault and Network Director Owen Sansom #IMGCGlasgow
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 07/04/2025
Ageing Cluster member Nicholas Schaum presenting the cluster and the work he’s doing to advance our understanding of the ageing process and the possible intervention points for a healthier life using #mouse cohorts at different age points #IMGCGlasgow #AgeingResearch @mrcharwell.bsky.social
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 06/04/2025
Workshops in full swing with two of them led by us. Robert Pitceathly and Carlo Viscomi of the MitoCluster with Andrew Wood of the Degron Cluster running the Mouse models of mitochondrial DNA disease workshop. Sara Wells and Sonia Bains running the Home cage monitoring one. #IMGCGlasgow #ECRS
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 06/04/2025
Waiting for the delegates to come and start the science rolling. Trainee workshops and symposium today! #IMGCGlasgow
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MRC MitoCluster @mrcmitocluster.bsky.social · 25/03/2025
Looking forward to #IMGC2025 Glasgow next month! MitoCluster will be delivering an #ECR Workshop on Mouse Models of #Mitochondrial DNA Disease, featuring cluster lead @robpitceathly.bsky.social and investigators Carlo Viscomi, @jim-ca.bsky.social, and @mitogene.bsky.social🐁
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London Mitochondrial Centre @londonmito.bsky.social · 25/03/2025
We're fundraising for the @lilyfoundation.bsky.social as part of their Mito Communi-TEA Party campaign this April! Join us at the National Hospital for Neurology & Neurosurgery next Friday 4th for a sweet treat 🦋 Donate & more info: www.justgiving.com/page/qsmito
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Cambridge Clinical Mitochondrial Research Group @mitocamb.bsky.social · 05/03/2025
Check out this exciting @faseborg.bsky.social conference with some top quality speakers, talking about #mito DNA mutation & repair! @mrc-mbu.bsky.social @mrcmitocluster.bsky.social @mbu-postdocs.bsky.social @jellevda.bsky.social @ritahorvath.bsky.social @mito-news.bsky.social
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Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social · 04/03/2025
#Training: Our DNA to Disease course will be running on 28th April and provides a comprehensive introduction into genetics, covering the genetic code and how this leads to protein formation, as well as how errors in DNA can lead to disease. Book now: www.har.mrc.ac.uk/training/cou...
har.mrc.ac.uk
DNA to Disease: Genetics for Beginners
This course provides a comprehensive introduction into genetics, covering the genetic code and how this leads to protein formation, as well as how errors in DNA can lead to disease.
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Cambridge Clinical Mitochondrial Research Group @mitocamb.bsky.social · 28/02/2025
📢 We have not 1 but 3 clinical/patient-facing jobs working with #mitoCAMB on the #LifeArc #raredisease centre for #mito diseases. 1x pre/post-doctoral CRA; 1x post-doctoral CRA (with potential to become a 4 year ACL); 1x research coordinator Join us! Links below.
QR code for 3 jobs
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MRC MitoCluster @mrcmitocluster.bsky.social · 24/02/2025
Great opportunity to discuss cross-cluster collaborations involving mitochondrial dysfunction with a talk by @robpitceathly.bsky.social
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 14/02/2025
We are #hiring for a number of positions in a new Data Science Team at the @cruk-si.bsky.social that will be delivering the National Mouse Genetics Network data platform, including this Data Science Team Leader role: Deadline: 28th February www.crukscotlandinstitute.ac.uk/careers/comp...
crukscotlandinstitute.ac.uk
Data Science Team Leader – Professor Crispin Miller
A senior position is available at Staff Scientist level within the Computational Biology Group at the CRUK Scotland Institute to lead a new Data Science Team. The Institute is a world leading cancer research institute situated in the vibrant city of Glasgow. It hosts approximately 60 researcher scientists at any one time. The Institute has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis.  
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MRC National Mouse Genetics Network @mrcmousenetwork.bsky.social · 20/02/2025
Our MURIDAE cluster, led by @profantisles.bsky.social is part of an international team that has been awarded £3.5 million to investigate how cognitive decline and premature brain ageing contribute to psychotic disorders like schizophrenia.
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MRC MitoCluster @mrcmitocluster.bsky.social · 18/02/2025
Collaborative paper with MitoCluster's Jim Stewart 📰 @mrcmousenetwork.bsky.social @mrcharwell.bsky.social #mitochondria #mousemodels
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MRC MitoCluster @mrcmitocluster.bsky.social · 18/02/2025
Welcome to our new account! You can also keep up to date with us on LinkedIn: www.linkedin.com/company/mrc-...
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