Reposted by Brett CollinsHourly Garth Marenghi's Darkplace @hourlydarkplace.bagpuss.org · 01/10/2026 0316
Reposted by Brett CollinsHourly Garth Marenghi's Darkplace @hourlydarkplace.bagpuss.org · 23/09/2026 327364
Reposted by Brett CollinsPrincess Vimentin PhD | Cancer Biologist @princess-vimentin.bsky.social · 02/10/2026October is #breastcancerawareness month. Did you know: Mary Claire King discovered the BRCA1 gene. In the 70s, she told people that one gene might be responsible for inherited breast cancer. No one believed her. In 1990, she found proof. It created a paradigm shift. It saved millions of lives.🧪 26922333
Reposted by Brett CollinsARC Tracker @arc-tracker.bsky.social · 02/10/2026ARC has given some details of how new Explore scheme will run ▶️ www.arc.gov.au/news-and-pub... ❗️There's a lottery❗️ Peer review yields 3 categories: highly competitive, competitive, uncompetitive. After funding highly competitive apps, competitive ones enter a lottery for remaining $. 32919
Reposted by Brett CollinsBen Schulz @benschulz.bsky.social · 02/10/2026Solving grant review lottery by adding an actual lottery! 🤦 241
Reposted by Brett CollinsBiochemical Society @biochemsoc.bsky.social · 30/09/2026Membrane Contact Sites in Cellular Homeostasis 2026 has officially wrapped. Thank you to our programme coordinators and delegates for the insightful discussions, new connections and outstanding science throughout the meeting. 094
Reposted by Brett CollinsSjors Scheres @sjorsscheres.bsky.social · 30/09/2026Our adventures into #proteinfolding: GuideFlip designs flexible molecular interactions by discrete flow matching to design sequence & structure together! Grateful for funding by Love Tito's (@titosvodka.bsky.social) and the @ukri.org. 🥳 02513
Reposted by Brett CollinsMelanie D. White @melaniedwhite.bsky.social · 01/10/2026I spoke with @nature.com about the Nikon Small World controversy. As AI becomes part of scientific imaging, we need greater transparency about what was measured, inferred or generated. It's not about excluding AI. It’s about preserving trust in scientific evidence. www.nature.com/articles/d41...nature.comThis award-winning microscopy image used AI — igniting controversy in a prestigious competitionResearchers say that using artificial-intelligence tools to visualize scientific images can become problematic when models misrepresent the underlying data. 44413
Reposted by Brett CollinsLadyBusiness @ladybusiness.bsky.social · 30/09/2026On my way to a job interview, smartly leaving the iced coffee at home 1224552619
Reposted by Brett CollinsMark Histed @markhisted.org · 29/09/2026Well-deserved. The guy is a hero and an inspiration 322242
Reposted by Brett CollinsMelanie D. White @melaniedwhite.bsky.social · 27/09/2026The Nikon Small World AI controversy has me worried. AI is transforming science, but what happens once it can generate “raw data” indistinguishable from real data? How do we embrace AI without losing confidence in the data underpinning scientific discovery? www.the-scientist.com/allegations-...the-scientist.comAllegations of AI Use in Nikon Competition Spark Controversy | The ScientistMicroscopists raise concerns about inappropriate AI usage in Nikon's microscopy contest-winning video. Nikon stands their ground, citing no policy breach. 2185
Reposted by Brett CollinsIn Otter News @in-otter-news.bsky.social · 26/09/2026After a long day at the aquarium, the otters help tidy their toys away. Payment is made promptly and entirely in ice cubes. 331188983967
Reposted by Brett CollinsA/Prof Sam Stehbens PhD (She/Her) @samstehbens.bsky.social · 26/09/2026#Nikon will address our concerns by next week. Hopefully the pre-processed movie & raw data will be part of that. #NikonSmallWorld 3268
Reposted by Brett CollinsRasmus Jensen @rasmusjensen.bsky.social · 25/09/2026🎉 Out today in Cell: the paper I've been looking forward to sharing for a long time 🎉 We used cryo-ET to find a molecular machine nobody knew existed on the surface of a minimal bacterium, and worked out what it does. 🧵(1/7) #TeamTomo #cryoET 1023296
Reposted by Brett CollinsAnh Hoang Le, PhD 🏳️🌈🏴🇻🇳 @anhhle2702.bsky.social · 25/09/2026Happy #FluorescenceFriday. The first time I imaged a 🐸 embryo, I didn't realise they had these ciliated cells on the outer surface. So you can imagine how surprised and curious I was! These cilia are similar to those found in the human airway. And yes, this is just a good old confocal + 🔥LUT! 59822
Reposted by Brett CollinsSlenderSherbet @slendersherbet.bsky.social · 24/09/2026"I don't fucking think so" 0850195
Reposted by Brett CollinsScott Barolo @sbarolo.bsky.social · 19/10/2023MR DARCY: Please disregard my last email. At the time I believed myself perfectly calm and cool, but I am since convinced that it was written in a dreadful bitterness of spirit, during faculty meeting 341583
Reposted by Brett CollinsARC Tracker @arc-tracker.bsky.social · 25/09/2026ARC has provided key dates for the next (supposedly final) Discovery Projects round (DP28) ▶️ www.arc.gov.au/funding-rese... Opens 1 Feb, closes 10 May 27. Outcomes not until Apr–May 28😔 (this is embarrassing) Look out for Guidelines in “late Oct” – remember, no rejoinder! So it’ll be…interesting 🧐arc.gov.au 384
Reposted by Brett CollinsVasilii Mikirtumov @vasiliimikirtumov.bsky.social · 24/09/2026thrilled to share that my main phd project is finally out in @natcomms.nature.com we present high-resolution structures of RyR1 in native membranes across multiple functional states by both cryo-ET/StA #TeamTomo and SPA! paper: www.nature.com/articles/s41... and a thread below⬇️⬇️⬇️ 45820
Reposted by Brett CollinsMaksim Kalutskii @maksimkalutskii.bsky.social · 23/09/2026Excited to share our new preprint! 📜 Here, we used CALVADOS and ultra-CG models to show how the kinetochore establishes a robust attachment to the dynamic microtubule end. Spoiler: IDRs 🧵 1/n www.biorxiv.org/content/10.6... 27737
Reposted by Brett CollinsWhat a week, huh? all Wednesdays @whataweekhuh.bsky.social · 23/09/2026 0264135
Reposted by Brett CollinsYuan He @yuanhejhu.bsky.social · 22/09/2026A big week for the lab! Two new papers on how cells repair DNA double-strand breaks: one on getting NHEJ started in chromatin, one on processing the ends before ligation. Years of work by a fantastic team. 410840
Reposted by Brett CollinsMartin Pacesa @martinpacesa.bsky.social · 21/09/2026ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/Bi... 4292142
Reposted by Brett CollinsJoe Bak-Coleman @jbakcoleman.bsky.social · 20/09/2026We can simulate fish schools or ants in ways that solve complex problems (gradient detection, bridge building, nest selection) but no one would create this weird soul/no-soul dichotomy to argue they these that multi-agent swarms of extremely simple rules are “thinking”. 14505169
Reposted by Brett CollinsDevelopment @dev-journal.bsky.social · 18/09/2026Pathway to Independence – an interview with Yamini Ravichandran In this interview, Yamini discusses her work focusing on understanding tissue-scale processes, regeneration and morphogenesis. doi.org/10.1242/dev.... 03113
Reposted by Brett CollinsStellbound: Stellraiser II @antlervel.vet · 18/09/2026Share if you agree 189103383304
Reposted by Brett CollinsMerja Joensuu @joensuulab.bsky.social · 17/09/2026Bringing the good energy! Thank you Garton T. Dodd and colleagues for highlighting our work and the emerging evidence on lipase DDHD2 and mechanisms enabling fatty acid mobilisation and oxidation in neurons. Read the beautifully written piece here: www.nature.com/articles/s44...nature.comNeurons run on fat - npj Metabolic Health and DiseaseNeurons were long thought to depend primarily on glucose metabolism for ATP production. However, recent findings from three laboratories show neurons metabolise long-chain fatty acids as alternative f... 133
Reposted by Brett CollinsMilot Mirdita @milot.bsky.social · 16/09/2026ColabFold 1.6.3 is out! 2.5x faster, pip-installable, ipSAE+pDockQ2 scores. Thanks Choonghwan Lee, Marielle Russo, Gyuri Kim 🐍pip install colabfold[alphafold] CF2 Sneak Peak with AF3/Boltz/Protenix/ESMFold2… 🐍pip install "colabfold[alphafold3]@git+https://github.com/sokrypton/ColabFold@af3-preview" 29736
Reposted by Brett CollinsSergey Ovchinnikov @sokrypton.org · 14/09/2026Finally a more intuitaive way to learn pLDDT/pAE? 😎 sokrypton.github.io/protein_figh... (Character idea from @hannes-stark.bsky.social & Alex Waldherr) 727698
Reposted by Brett CollinsLuca @lucagalletti.bsky.social · 13/09/2026Short film about hope www.reddit.com/r/funny/s/CG... 1951524323
Reposted by Brett CollinsIn Otter News @in-otter-news.bsky.social · 12/09/2026Important otter tummy content: 332379281
Reposted by Brett CollinsWorld Bollard Association™️ @worldbollardassoc.bsky.social · 12/09/2026The Marge Simpson bollard. #WorldBollardAssociation 6184411032
Reposted by Brett CollinsHauke Hillen @haukehillen.bsky.social · 11/09/2026Happy to share our new preprint on the structure of the human mitochondrial RNA degradosome, a central player in organellar RNA metabolism! Work led by graduate student @paulafprado.bsky.social in our group. www.biorxiv.org/content/10.6... 🧵 1/9 19134
Reposted by Brett CollinsMelanie D. White @melaniedwhite.bsky.social · 11/09/2026Happy #FluorescenceFriday! ✨ It's the glue that holds us together, but it looks like a pair of angel wings to me. 👼 This beautiful meshwork of extracellular matrix surrounds the developing tissues of a quail embryo, helping guide cells as they build the body. 📷 @wangjianxiong.bsky.social 🔬 07415
Reposted by Brett CollinsKranzusch Lab @kranzuschlab.bsky.social · 10/09/2026Stunning cryo-ET analysis from the Harrison Lab capturing every stage of how non-membrane viruses infect animal cells www.science.org/doi/10.1126/... 08326
Reposted by Brett CollinsJason Rasgon @vectorgen.bsky.social · 09/09/2026The text I just sent to my spouse... 6373
Reposted by Brett CollinsGuillaume Thibault @gthibault.bsky.social · 10/09/2026Singapore Bioscience Symposium 2026 reminder. Abstract submission and early bird registration both close 30 September. The lineup includes 9 keynotes, 18 invited speakers, 12 countries. Details 🧵👇 075
Reposted by Brett CollinsRoland Pierik @roleo.eurosky.social · 08/09/2026The number of cases of cervical cancer reported in Scotland among women given the HPV vaccine at 12-13 years of age is now zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. Zero. www.bbc.com/news/article...bbc.comNo cervical cancer cases in fully HPV-vaccinated women in ScotlandA study published by Public Health Scotland finds that the HPV vaccine is "highly effective". 6360692263
Reposted by Brett CollinsJanet Iwasa @jiwasa.bsky.social · 09/09/2026Interested in molecular animation? Give ProteinBlender a try! It's free and open source. animation-lab.github.io/ProteinBlend... The latest tools include a DNA builder (shown in the tutorial video below). We'd love to hear what you think! We have short tutorials that cover all the features! 19542
Reposted by Brett CollinsIshier Raote @ishier.bsky.social · 07/09/2026Membrane Trafficking Seminar Series 2026 fall season is here! An exciting programme: membrane traffic, organelle biogenesis, lipid transport, endomembrane evolution, we have it all! Save the dates and join us for fun science and discussions. Details at felixcampelo.wixsite.com/membranetraf... 22725
Reposted by Brett CollinsARC Tracker @arc-tracker.bsky.social · 08/09/2026To the many unsuccessful Future Fellowship applicants who got great scores (& feedback) from their peer ("Detailed") reviewers, but much poorer scores from their ARC College ("General") assessors, here's an old thread explaining why this happens👇 And, by the way, I'm sorry – the system ain't great. 2346
Reposted by Brett CollinsAleksandra Filipovska @filipovskalab.bsky.social · 08/09/2026We’re hiring! 🧬 Exciting opportunities in mitochondrial genome engineering and therapies for mitochondrial disease with @FilipovskaLab in sunny Western Australia ☀️ and at our new biotech CodeBreakers Apply: au.seek.com/job/94426759 #Mitochondria #GenomeEngineering #Postdoc #Biotech 055
Reposted by Brett CollinsIn Preparation @inprep.bsky.social · 08/09/2026inpreparation.substack.com40% Of PhD Now Spent Selecting ‘All Squares Containing Bicycles’BALTIMORE, MD—A study published Tuesday in PLOS ONE found that approximately 40% of doctoral training is now spent confirming the researcher is not a robot, primarily through the selection of squares… 07020
Reposted by Brett CollinsARC Tracker @arc-tracker.bsky.social · 07/09/2026ARC says they'll announce outcomes of Future Fellowships (FT26) tomorrow (Tue 8 Sep). In recent times, these announcements have been around 11am Canberra time, though certainly with some variation. My bot will automatically post within a minute after the announcement. 64713
Reposted by Brett CollinsMagnus Bauer @kinasekid.bsky.social · 06/09/2026AlphaFold Server’s ligand menu just got a lot bigger and I almost missed it! You can now add any ligand from the wwPDB Chemical Component Dictionary. Just enter its CCD code 🥳 16028
Reposted by Brett CollinsJonathan Edward Durham @thisone0verhere.bsky.social · 04/09/2026I’m beginning to think waking up and immediately reading the most insane things anyone has ever read is not exactly great for me 2095384546
Reposted by Brett CollinsJake Wright @bcnjake.bsky.social · 04/09/2026Hey, students. If you did something cool and you have a faculty member who helped you do it, like write a letter of rec, tell us about it! We want to be proud and excited for you! I had a student come in yesterday to tell me they got into grad school, and it absolutely made my week. 0164
Reposted by Brett CollinsSlenderSherbet @slendersherbet.bsky.social · 04/09/2026When they call your name in a work meeting and you weren't listening. 19190998
Reposted by Brett CollinsLorne Proteins @lorneproteins.bsky.social · 04/09/2026Abstract submissions are now open for Lorne Proteins 2027! Applications for eligible awards 🏆 and bursaries 💸 are via the same portal: ➡️ www.lorneproteins.org/submissions Register today to join researchers from all over the world, converging on a small seaside town in Victoria, Australia! 066
Reposted by Brett CollinsAparna Nair @disabilitystor1.bsky.social · 04/09/2026with every word this headline got worse and worse 410830