iiinova — where your digital self keeps evolving

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 12h

Microglia are best known as the brain's cleanup crew. New paper from @dgsomucla.bsky.social @ladenardo.bsky.social & Lindsay De Biase shows they're just as important for building synapses. Great reminder that immune cells shaping our brains do far more than tidy up. www.nature.com/articles/s41...

Drs. De Biase and DeNardo standing in a lab next to a microscope.

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Sara J Hussain @sarahussain.bsky.social · 27/09/2026

Looking forward to this one - nice cross disciplinary program tackling the problem of recovery after neural damage!

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Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · 14/09/2026

This is a first of a kind conference on recovery ranging from basic science to translational neuroscience. Looking forward to it! Please see below for deadlines for abstracts, scholarships, etc.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 16/09/2026

A message from our Theme leader @annechurchland.bsky.social representing @dgsomucla.bsky.social at a rally for medical research in Washington D.C. #rallyformedicalresearch #neuroscience #cancerresearch #advocacy

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Carlos A. Sánchez León @carlosasleon.bsky.social · 13/09/2026

Huge thanks to my co-authors and the amazing team at UCLA! (porteralab.dgsom.ucla.edu) Thanks for reading, and remember: Dale a tu cuerpo alegría _____! 🙌 Read the full preprint here: doi.org/10.64898/202... 📄

porteralab.dgsom.ucla.edu

Portera-Cailliau Research Lab

The Portera-Cailliau Lab studies neurodevelopmental disorders, using circuit neuroscience to identify therapies for autism and intellectual disability.

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Keystone Symposia @keystonesymposia.bsky.social · 09/09/2026

Calling all neuroscientists 🧠 $1500 scholarship app + short talk deadlines are approaching! Sept 22: Sensory Systems + Appetite Control Sept 24: Neurodevelopmental Disorders + Neural Plasticity & Recovery 4 Neuro meetings, 1 week in January, 30 min apart in the CO Rockies.

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Keystone Symposia @keystonesymposia.bsky.social · 09/09/2026

Sensory Systems 🔗 hubs.la/Q04x3Q6m0 Appetite Control 🔗 hubs.la/Q04x3Q880 Neurodevelopmental Disorders 🔗 hubs.la/Q04x3Qp40 Neural Plasticity & Recovery 🔗 hubs.la/Q04x3Qxb0

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Sahib Khalsa @skhalsa.bsky.social · 08/09/2026

Postdoc job alert! I’m looking for someone with a PhD in neuroscience/psychology, psychiatry, computational modeling or a related field to join my NIH-funded team at UCLA studying the neural & computational mechanisms of #interoception in anorexia nervosa 1/2

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Samantha Butler @samanthabutler.bsky.social · 02/09/2026

Please spread the news - the Department of Neurobiology at UCLA is hiring. This is an open rank search for all and any amazing neuroscientists! Please apply here by Nov 15th, first review end of October : recruit.apo.ucla.edu/JPF11296

recruit.apo.ucla.edu

Open-rank tenure-track faculty position

University of California, Los Angeles is hiring. Apply now!

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 01/09/2026

How does early scientific discovery become real hope for patients? The 1st UCLA Neurology newsletter is here, illuminating @dgsomucla.bsky.social discoveries that can change lives. ✨ Read about researchers developing therapies for #Alzheimers, studying #Parkinsons disease, & more! t.co/ABSlAls3Uv

Picture of four lighthouses decreasing in size and increasing in brightness of the light shining.

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Joe Sabatino @jsabatino37.bsky.social · 31/08/2026

🚨If you are a CA resident, please be aware of Prop 38, which is on the ballot this Nov. This initiative will provide $8.4 billion to advance breakthrough immunology research and treatments w/ half the funds dedicated to Alzheimer’s, cancer, and heart disease 1/

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Thanh Neville, MD, MSHS @thanh-neville.bsky.social · 31/08/2026

Getting NIH funding has always been crazy & now nearly impossible. My reaction was fuck that, I'm not doing this anymore. I learned UCLA has maintained our same amount of $$ NIH funding this past year, bc researchers have submitted TWICE as many grant proposals. Such resilience that I don't have.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 21/08/2026

Why can't we remember things from infancy? New from @ladenardo.bsky.social @dgsomucla.bsky.social lab: brain region called retrosplenial cortex physically matures on same timeline memories shift from fleeting to permanent. Great insight on how architecture of #memory itself develops: t.co/m4Rsx1vsVV

A 2x3 grid of fluorescence microscopy images comparing retrocortical / retrosplenial cortex (RSP) neuronal labeling across three developmental stages (Infant, Juvenile, Adult) under two behavioral conditions: CFC (Contextual Fear Conditioning, top row) and NS (Non-Shocked control, bottom row). Cell nuclei are stained in blue (DAPI), with active neuronal ensembles labeled in magenta/pink (TRAP, Fos) marked by dashed white circles.

Summary of the Image Content:
* Columns (Age Groups): Displays the progression of retrosplenial cortex maturation from Infant to Juvenile and Adult.
* Rows (Conditions):
* CFC (Top): Shows context-dependent fear conditioning memory-evoked cellular activation.
* NS (Bottom): Shows baseline/non-shocked control activation.
* Markers: Fluorescent staining highlights TRAP (tdTomato), Fos expression, and DAPI nuclear counterstain, demonstrating an increase in specific, learning-evoked ensemble reactivation as animals mature.

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Sara J Hussain @sarahussain.bsky.social · 19/08/2026

Interested in rehab, motor control, neurophysiology, and neuroengineering? Our group is recruiting a new PhD student for fall 2027. Funding is available via a research or teaching assistantship. See attached for info, and please share!

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 12/08/2026

The developing brain isn't just a biological puzzle; it's a metabolic one. New paper from Aparna Bhaduri's lab at @dgsomucla.bsky.social creates 1st metabolic atlas of early human cortex, revealing glucose metabolism plays direct role in shaping which cell types the brain produces: t.co/VcIW6QaWet

These are images of cortical organoids stained for SOX2, CTIP2, and DAPI (columns) at weeks 5, 8, 10, 12, and 15 (rows). Ratio of SOX2 or CTIP2 to DAPI+ cells. Data are from 3 stem cell lines (KOLF, circles; UCLA6, squares; UCLA1, triangles), 13–40 technical replicates are used for each time point, w/ unique regions of organoids across all three stem cell lines. Adjacent time points compared only.

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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 12/08/2026

Join researchers exploring neurodevelopmental disorders—from single-cell genomics & gene–environment interactions to emerging therapies | @keystonesymposia.bsky.social 📅 Jan. 19–22 | Breckenridge 🎓 Scholarships + Short Talk Abstracts due Sept 24 keysym.us/KSNDDs27 #KSNDDs27

keysym.us

Neurodevelopmental Disorders: Mechanisms and Therapeutics | Keystone Symposia

Join us at the Keystone Symposia on Neurodevelopmental Disorders: Mechanisms and Therapeutics, January 2027, in Breckenridge, with field leaders!

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The Lewy Body Society @lewybodysociety.bsky.social · 11/08/2026

Twelve years ago today #RobinWilliams died. No one knew at the time he had #Lewybodydementia. His wife Susan Schneider Williams wrote a powerful piece about Robin and the disease that had caused him so much pain.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 10/08/2026

A new award from the @simonsfoundation.org recognizes research from @dgsomucla.bsky.social's João Couto. His ultra-high-throughput approach for measuring neural activity has the potential to tackle unanswered questions in #autism research. Learn more: www.simonsfoundation.org/2026/07/31/a... #UCLA

João Cuoto smiling with his arms crossed while wearing a gray shirt, standing in front of a brick and cement arch outside of Royce Hall at UCLA.

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Aligning Science Across Parkinson's @asapresearch.parkinsonsroadmap.org · 28/07/2026

#TeamTuesday 🌱 CRN Team Khurana, one of our new PD Heterogeneity teams, is studying how pesticide exposures may shape #Parkinsons biology and clinical subtypes. Their work combines cohort data, stem-cell models, alpha-synuclein biomarkers, and AI tools. 🔗 bit.ly/4wVuHt4

Graphic introducing CRN Team Khurana’s project, “Fingerprinting How Pesticide Exposures Shape Parkinson’s,” which integrates epidemiology, stem-cell models, biomarkers, and AI across three longitudinal Parkinson’s cohorts. Team members pictured are Lead PI Vikram Khurana and Co-PIs Kimberly Paul, Beate Ritz, David Walt, and Marinka Zitnik.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 27/07/2026

Meet the newest generation of UCLA neuroscientists. Last year's incoming PhD trainees are now joining labs & beginning research that will define the next chapter of brain science. They arrived full of curiosity & ambition during trying times & we are proud to have them at @dgsomucla.bsky.social!

Newest generation of UCLA neuroscientists standing in three rows on stairs outside of UCLA.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 24/07/2026

Stroke is the leading cause of adult disability & most survivors never fully recover. Tom Carmichael, chair of Neurology at @dgsomucla.bsky.social, has identified a drug that mimics physical rehabilitation by restoring brain rhythms disrupted by #stroke. A pill for stroke recovery. t.co/a646Zo6j5c

A three-panel scientific figure comparing brain structures across three conditions: Sham, Stroke, and Stroke + Rehab. The top row shows high-resolution fluorescence microscopy images of green dendritic spines on neurons, displaying loss of spines after stroke and recovery with rehab. The lower panels present outline diagrams of the mouse brain mapping functional motor and somatosensory cortical areas (labeled cRFA, iRFA, and SS) with highlighted connections.

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The Parkinson's Foundation @parkinsondotorg.bsky.social · 20/07/2026

Parkinson’s disease can cause attention, memory, language and problem-solving difficulties, sometimes appearing at diagnosis and progressing slowly. Learn about managing these PD symptoms: Parkinson.org/understanding-parkinsons/non-movement-symptoms/cognitive

parkinson.org

Cognitive Changes

Brain changes that lead to motor symptoms can also result in slowness in memory and thinking.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 16/07/2026

Aficionado's corner: An aptamer is a short single-stranded piece of DNA or RNA that is designed to bind very specifically to a target molecule, much like an antibody does but with some advantages. The name comes from the Latin "aptus" meaning "to fit." The aptamer they use here is called 1R6.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 14/07/2026

Glioblastoma tumor cells behave like cells from a developing brain, proliferating w/o normal controls. Aparna Bhaduri's lab at @dgsomucla.bsky.social is using what we know about cortical development to understand why & find new therapeutic targets. Neuroscience meets cancer biology. t.co/VLyfqOEpPv

A scientific flow chart and diagram titled "Tumor Periphery," "Hypoxia and Immune Response States," and "Tumor Core," illustrating the microenvironment and cellular transitions of Glioblastoma (GBM).

Tumor Core: Shown on the bottom left as a brain illustration with a highlighted red tumor mass, leading into an "Immune-infiltrated" cellular cluster, as well as "Vascular" and "Neurovascular" cell types.

Hypoxia and Immune Response States: A central circular pathway depicts transitions between "MES progenitor" cells and "MES" cells, alongside dividing cells.

Tumor Periphery: The right side of the diagram details "Neurodevelopmental States," showing progenitor cells (RG and oRG) differentiating into neural lineages including neurons (purple), oligodendrocytes (green), astrocytes (blue), NPCs, and OPCs.

Arrows indicate the dynamic cellular plasticities and cycling between these different states and regions. A citation reads "Martija A, Bhaduri A. 2026. Annu. Rev. Neurosci. 49:19-37”

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ZeigerLab @zeigerlab.bsky.social · 10/07/2026

The Keystone meeting on neural plasticity after CNS injury is ~6 months away. Time to start planning and getting excited. We’ve got promos! urldefense.com/v3/__https:/...

urldefense.com

YouTube

Share your videos with friends, family, and the world

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Aligning Science Across Parkinson's @asapresearch.parkinsonsroadmap.org · 07/07/2026

#TeamTuesday 🌱 CRN Team Bronstein, one of our new PD Heterogeneity teams, is studying how environmental toxins and genetic factors may shape #Parkinsons progression. Their work uses stem cells and animal models to examine vulnerability to faster progression. 🔗 bit.ly/4waZHVM

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 06/07/2026

Parkinson's is the fastest growing neurological disorder & aging alone can't explain it. A @dgsomucla.bsky.social study links air toxics in CA's Central Valley to #parkinsons risk. Nickel, benzene & 1,3-butadiene all show striking associations. sciencedirect.com/science/article/pii/S0048969726006637

$Choropleth map of California's Central Valley focusing on Fresno, Tulare, and Kern counties, illustrating workplace exposure levels to Nickel measured in nanograms per cubic meter ($\text{ng/m}^3$). A legend labeled "A. Nickel ($\text{ng/m}^3$)" categorizes exposure into five color-coded ranges from pale beige ($1.56 - 1.86$) to dark red ($2.04 - 2.23$), with Kern and Fresno counties highlighted in the highest concentration tiers.$

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 04/07/2026

Tonight’s fireworks are a full-brain workout: color and motion engage the visual system, booms recruit multisensory circuits, surprise triggers dopamine, and watching together amplifies the experience. Evolution built us to find meaning in sensation. Happy 4th from @UCLA Neuroscience!

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Craig Brown @craigedbrown.bsky.social · 03/07/2026

Very pleased to share our latest (now published), from star student Kamal Narayana. He finds lowering (not increasing) peri-infarct blood flow beyond the hyper-acute phase, improved stroke recovery by lessening blood brain barrier disruption and neuro-inflammation. www.nature.com/articles/s41...

nature.com

Knockdown of endothelial Serpine1 improves stroke recovery by attenuating peri-infarct blood flow and blood-brain barrier disruption - Cell Death & Disease

Cell Death & Disease - Knockdown of endothelial Serpine1 improves stroke recovery by attenuating peri-infarct blood flow and blood-brain barrier disruption

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Aligning Science Across Parkinson's @asapresearch.parkinsonsroadmap.org · 29/06/2026

🧪 How do environmental exposures, like pesticides and chemicals, shape #Parkinsons risk, and point us toward new therapeutic strategies? Four CRN teams are studying how toxins interact with biology and genetics to drive disease, opening new paths for prevention and treatment. bit.ly/44wpUlv

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CMU Mellon College of Science @cmuscience.bsky.social · 16/06/2026

Neurosicientist Aryn Gittis and colleagues show Parkinson’s symptoms like tremor and slowed movement arise from different brain circuits, a finding that could lead to more targeted, personalized treatments. 🧪 #WomenInSTEM www.cmu.edu/mcs/news-eve...

cmu.edu

Parkinson’s Symptoms Trace to Distinct Brain Circuits

Carnegie Mellon University’s Aryn Gittis and colleagues suggest the most recognizable symptoms of Parkinson's disease result from disruptions in different motor circuits of the brain, an insight that ...

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Paul Tuite @tuite002.bsky.social · 12/06/2026

The Researcher Who Didn’t Want to Know www.nytimes.com/2026/06/11/s...

nytimes.com

The Researcher Who Didn’t Want to Know

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 04/06/2026

What does it take to understand the brain? At UCLA, it takes a community. More than 320 #neuroscience labs across medicine, science, and engineering are working together to advance discovery & develop new approaches to neurological & psychiatric disorders. Learn more in today's video. #brainhealth

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 21/05/2026

@annechurchland.bsky.social also appreciates the Parkinson’s symposium was made freely available online afterward. Making research conversations accessible to patients, families, & caregivers should be part of how we build trust, understanding & community around neurodegenerative disease research.

youtube.com

Exploring the Latest in Parkinson's Disease Research and Treatment at UCLA

YouTube video by UCLA Neurology

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 21/05/2026

That is why community-focused events like this symposium matter so much. They create space not just for education, but for connection.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 21/05/2026

Organized by William Zeiger (@zeigerlab.bsky.social) the event reflects something I think we need more of in medicine & neuroscience: making research conversations more accessible to the people most impacted by these diseases. Grateful for support of the UCLA BRI in making events like this possible.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 21/05/2026

As part of this week’s spotlight on neurodegeneration research, we're highlighting a recent @dgsomucla.bsky.social Parkinson’s symposium. Patients, families & community were invited to engage directly with researchers & learn more about the science shaping the future of #parkinsons treatment.

Drs. Katy Cross, Lindsay De Biase, Jeff Bronstein, Will Zeiger, Chao Peng, Gal Bitan, and Dani Thordarson standing in front of a projector screen at the UCLA Brain Research Institute Parkinson’s Disease Research Community Outreach Symposium at the David Geffen School of Medicine at UCLA.

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Michael Williamson @m-r-williamson.bsky.social · 19/05/2026

Thrilled to share that I’ll be starting my lab at the SickKids Research Institute and University of Toronto in August! williamsonlab.ca Recruiting at all levels. Get in touch if you’re interested in astrocyte biology of cognition and disease!

williamsonlab.ca

Williamson Lab

The Williamson Lab studies astrocyte biology across development, cognition, and disease.

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UCLA Neuroscience Theme @uclaneurotheme.bsky.social · 08/05/2026

Exciting new research identifies specific neural circuits that appear to be restored by brain stimulation therapies to rapidly relieve severe #depression. From @dgsomucla1.bsky.social's @michaelgongwer.bsky.social, @ladenardo.bsky.social & @scottwilke5.bsky.social. Read more: t.co/0b4CEmfTly #TMS

Graphical abstract of a mouse model of repetitive transcranial magnetic stimulation (rTMS)

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Sara J Hussain @sarahussain.bsky.social · 26/04/2026

📣 Postdoc in Human Neurophysiology & Neurorehab 📣 The Real-Time NeuroRehabilitation Lab at the U of Iowa is hiring a Postdoctoral Research Scholar! Motor control, EEG/TMS, neurorehabilitation, and real-time multimodal methods. 📅 Summer/Fall 2026 📧 sara-hussain@uiowa.edu Please share!

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ZeigerLab @zeigerlab.bsky.social · 21/04/2026

We’re recruiting! Come join our lab as a staff research assistant. Lots of interesting skills to learn - 2P imaging, behavior, disease models, and more! www.uclahealthcareers.org/job/23287056...

uclahealthcareers.org

Staff Research Associate I - Neurology - UCLA Health Careers - Job #30035 - Los Angeles, CA

Take a look at a great career opportunity where you can make a real difference at UCLA Health

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International Parkinson and Movement Disorder Society® @movedisorder.bsky.social · 11/04/2026

In honor of #worldparkinsonsday, lets acknowledge some of the researchers and clinicians who have advanced our understanding of PD. Identified alpha-synuclein as a major component of Lewy bodies, clumps of proteins found in Parkinson’s disease and dementia with Lewy bodies.

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International Parkinson and Movement Disorder Society® @movedisorder.bsky.social · 11/04/2026

In honor of #WorldParkinsonsDay, let's acknowledge James Parkinson — the first person to document "paralysis agitans," now known as Parkinson's disease, within his work "An Essay on the Shaking Palsy."

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