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UCSF Broad Stem Cell Center

@ucsfstemcell.bsky.social
945 followers 407 following 46 posts

Discovering the inner workings of stem cells, engineering treatments using genome editing tools, and healing patients by developing life-saving therapies.

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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 29/09/2026
Congratulations, Dr. Licia Selleri, recipient of the 2026 David Bixler Distinguished Scientist Award. This is the highest honor of @scgdb.bsky.social, reflecting Dr. Selleri's extensive accomplishments in craniofacial research and contributions to the community. We are #UCSFProud!
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Leslie B Vosshall PhD @leslievosshall.bsky.social · 18/09/2026
Transformative opportunity for early career faculty @hhmi-science.bsky.social #FreemanHrabowski Scholars competition opens 11/3/2026 but you can get started NOW: view application components, establish eligibility, and unlock example applications and other resources www.hhmi.org/programs/fre...
hhmi.org
Early Career Faculty Program | Freeman Hrabowski Scholars | HHMI
The Freeman Hrabowski Scholars Program offers comprehensive support to outstanding early career faculty committed to scientific excellence in their own research, and to fostering labs that expand the ...
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Reposted by UCSF Broad Stem Cell Center
UCSF @ucsanfrancisco.bsky.social · 27/08/2026
What if doctors could use your own tumor to teach your immune system to destroy cancer? UCSF scientists may have found a way. By coating lab-grown immune cells with pieces of a patient’s own tumor, they trained T cells to recognize and attack the cancer. ow.ly/JJZ450ZGgZ4
ow.ly
How to Teach T Cells to Track Cancer Like a Hound Dog
Scientists made universal stem-cell-derived dendritic "immune teacher" cells that can be coated with a patient’s tumor proteins, creating a cancer vaccine that activated tumor-killing T cells in laboratory studies, patient samples, and mouse models.
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Reposted by UCSF Broad Stem Cell Center
UCSF @ucsanfrancisco.bsky.social · 11/09/2026
Their work has advanced health and improved lives around the world. Congratulations to the 2026 UCSF Medal recipients on receiving UCSF’s highest honor for their lasting contributions to health and society. www.ucsf.edu/news/2026-ucsf-medal
Five professionally dressed individuals standing together in front of a beige curtain at a formal event or conference.
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Institute for Human Genetics at UCSF @ihgatucsf.bsky.social · 14/09/2026
Take a break and have lunch with Novogene :) humangenetics.ucsf.edu/tech-seminar...
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 25/08/2026
@robertblelloch.bsky.social + team engineered iPSC-derived dendritic cells coated w/ patient tumor membranes to present multiple cancer antigens to T cells. The approach induced tumor-specific T cell responses in patient samples and slowed tumor growth in humanized mice. www.cell.com/cell-stem-ce...
cell.com
Engineered human iPSC-derived dendritic cells dressed with tumor MHC complexes as a cancer vaccine
Blelloch and colleagues create genetically engineered universal human iPSCs, differentiate them into CCR7+ migratory dendritic cells, and dress them with tumor-derived MHC class I-antigen complexes to...
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Reposted by UCSF Broad Stem Cell Center
Juan Moriano @juanmoriano.bsky.social · 19/08/2026
1/4 Thrilled to launch this space with our latest preprint on the developmental trajectory of Broca's area in the human brain doi.org/10.64898/202...
doi.org
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Institute for Human Genetics at UCSF @ihgatucsf.bsky.social · 18/08/2026
@ihgatucsf.bsky.social and @ucsfstemcell.bsky.social are excited to invite you to the Genotech Symposium on September 23! 📍 NEW LOCATION: Fisher Banquet Room, 1st Floor, Rutter Center Join us to foster collaboration between industry and academia in genetics and genomics! genotech.ucsf.edu
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 13/08/2026
Congratulations to Kyle Cromer, PhD, on receiving Emily’s Entourage’s first 2026 Translational Research Grant. The project tackles a key challenge in CF gene therapy: helping corrected airway stem cells expand and persist to repair lung tissue. More: www.emilysentourage.org/emilys-entou...
emilysentourage.org
Emily’s Entourage Funds Synthetic Biology Approach to Enable Durable Gene Therapy for Cystic Fibrosis - Emily's Entourage
Engineered synthetic receptor technology aims to selectively expand corrected airway stem cells and improve long-term treatment durability. Lower Merion, PA—August 13, 2026—Emily’s Entourage (EE), an ...
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 12/08/2026
Join researchers exploring neurodevelopmental disorders—from single-cell genomics & gene–environment interactions to emerging therapies | @keystonesymposia.bsky.social 📅 Jan. 19–22 | Breckenridge 🎓 Scholarships + Short Talk Abstracts due Sept 24 keysym.us/KSNDDs27 #KSNDDs27
keysym.us
Neurodevelopmental Disorders: Mechanisms and Therapeutics | Keystone Symposia
Join us at the Keystone Symposia on Neurodevelopmental Disorders: Mechanisms and Therapeutics, January 2027, in Breckenridge, with field leaders!
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 10/08/2026
Congratulations to Dr. Tara McIntyre, selected as a 2026 Life Sciences Research Foundation (LSRF) Fellow to investigate the Mechanisms and consequences of immune aging in reproduction in Dr. Diana Laird's lab: lsrf.org/wp-content/u...  #basicresearch #lifesciences #postdocfunding #earlycareer
Smiling woman in nature setting next to colorful Life Sciences Research Foundation logo
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Institute for Human Genetics at UCSF @ihgatucsf.bsky.social · 29/07/2026
@ihgatucsf.bsky.social and @ucsfstemcell.bsky.social are excited to inform you about the annual Genotech Symposium, taking place on 9/23. The goal is to foster collaboration and cross-fertilization between industry and academia in genetics and genomics. Hope to see you there! genotech.ucsf.edu
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UCSF Health @ucsfhealth.bsky.social · 03/03/2026
Exercise protects the brain, and now UCSF researchers may have discovered how: An exercise-induced protein appears to strengthen the blood-brain barrier, slowing decline. “We’re uncovering biology that Alzheimer’s research has largely overlooked,” Saul Villeda says. ucsfh.org/4aAJ9OQ
ucsf.edu
Scientists Find a Mechanism for How Exercise Protects the Brain
A UCSF team finds a liver protein, released with exercise, that improves memory in aging and Alzheimer’s disease by repairing the brain’s blood vessels. It's the missing link between exercise and brai...
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Reposted by UCSF Broad Stem Cell Center
Jeremy Reiter @reitergroup.bsky.social · 09/06/2026
Congratulations, @konjikusicmia.bsky.social. It makes my heart well up to have this cohort named in memory of Zara, an extraordinary scientist.
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 11/06/2026
Congratulations, Corey Harwell, PhD, on being named a 2026 McKnight Neurobiology of Brain Disorders Award recipient. His work investigates how brain circuits are built and how disruptions in these pathways may contribute to neurological and developmental disorders: stemcell.ucsf.edu/news/corey-h...
smiling man in light green shirt in a lab setting adjacent text reading McKnight Foundation 2026 Neurobiology of Brain Disorders Awards
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 19/05/2026
Excited to have the ISSCR 2027 Annual Meeting here in San Francisco! 🧬
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UCSF Helen Diller Family Comprehensive Cancer Center @ucsfcancer.bsky.social · 09/03/2026
Research led by Tomasz Nowakowski, PhD @ucsanfrancisco.bsky.social @ucsfstemcell.bsky.social in @nature.com | New map of fetal brain cell development may change our understanding of mental illness and cancer www.earth.com/news/new-map... #UCSFProud
earth.com
New map of fetal brain cell development may change our understanding of mental illness and cancer
A chronological map of the fetal brain reveals when key cells emerge and provides clues about autism and cancer.
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 19/02/2026
Peng He & colleagues published “Toward informed batch correction for single-cell transcriptome integration” in Nature Computational Science. They review current data cleaning methods & envision interpretable frameworks that model technical + biological variation in single-cell data: rdcu.be/e4cSp
rdcu.be
Toward informed batch correction for single-cell transcriptome integration
Nature Computational Science - Batch effects pose substantial challenges for obtaining meaningful biological insights from large-scale yet heterogeneous single-cell RNA-sequencing datasets. Here...
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 09/02/2026
15 years ago today, @ucsanfrancisco.bsky.social celebrated the opening of the Ray & Dagmar Dolby Regeneration Medicine Building on our Parnassus campus. Take a look back at scenes from opening day and move-in, and see what our researchers are working on today: stemcell.ucsf.edu/2024-2025-uc...
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 05/02/2026
The UCSF Broad Stem Cell Center and Department of Surgery invite applications for a new faculty position focused on the development of delivery tools for gene editing to enable cutting-edge gene therapies. Please share and apply 🔗 aprecruit.ucsf.edu/JPF05914
UCSF Broad Stem Cell Center hiring ad. Modern building and lush greenery. Announces faculty position in gene editing delivery. Includes a QR code for applying.
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Nature @nature.com · 25/01/2026
Nature research paper: Dissecting gene regulatory networks governing human cortical cell fate go.nature.com/4qBG5rp
go.nature.com
Dissecting gene regulatory networks governing human cortical cell fate - Nature
Systematic screening of transcription factors reveals conserved mechanisms governing cortical radial glia lineage progression across primates and provides a framework for functional dissection of gene regulatory networks in human cortical neurogenesis.
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 18/12/2025
Researchers in Diana Laird's lab discovered the decline in female fertility w/age isn’t driven solely by eggs; other cells in the ovary, including glia and fibroblasts, influence ovarian health & aging—part of UC’s top discoveries of 2025. #UCSFProud www.universityofcalifornia.edu/news/10-awes...
universityofcalifornia.edu
10 awesome discoveries from UC research in 2025
A year of new treatments, new technologies, new ways to stay safe during disasters and new insights on the mysteries of the galaxy, our planet and our past.
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 12/11/2025
Kyle Cromer's team published collaborative work with Stanford in @bloodadvances.bsky.social using CRISPR tools to create a mouse model of a rare juvenile leukemia. Congrats to Roshani Sinha, Devesh Sharma, & Benjamin Lesch for co-authoring this publication. More: ashpublications.org/bloodadvance...
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Alex Pollen @brainevodevo.bsky.social · 07/11/2025
Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...
nature.com
Conservation and alteration of mammalian striatal interneurons - Nature
An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...
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Reposted by UCSF Broad Stem Cell Center
UCSF @ucsanfrancisco.bsky.social · 07/11/2025
Happening TODAY! Tune in at noon for #UCSFSOTU 2025 with Chancellor Sam Hawgood. Hear about UCSF’s accomplishments from the past year and how our institution is innovating to adapt for the future. tiny.ucsf.edu/HuBTYF
tiny.ucsf.edu
State of the University Address
Live viewing page of the annual UCSF Chancellor's State of the University Address.
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Johanna Joyce @johannajoyce.bsky.social · 05/11/2025
New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) 🧠🧪🔬 An amazing set of resources for all scientists working on the brain! 🧠 Immersive feature: www.nature.com/immersive/d4... 🧠 Perspective: www.nature.com/articles/s41...
Cover of this week's Nature showing a brain rendering

Cover caption from the journal:
Brain development:
Our ability to process information into complex emotions, behaviours and decisions relies on the rich diversity of cell types that make up the human brain. Uncovering the molecular and cellular events that take place during brain development could reveal not only the mechanisms that give rise to this diversity but also shed light on how this process might go awry in neurodevelopmental disorders such as autism and schizophrenia. In this week’s issue, the BRAIN Initiative Cell Atlas Network (BICAN) builds on its previous work creating atlases of cell types in the adult mouse, non-human primate (NHP) and human brains to present cell-type atlases of the developing human, mouse and NHP brains. Across a suite of papers, nine of which are published in Nature, the researchers uncover the complex programs through which cell types emerge during brain development in humans and animals, revealing both the shared and unique features of the human brain. The latest work, along with future research directions, is summed up in a Perspective article by Tomasz Nowakowski and colleagues
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Leading Edge Fellows Program @leadingedgeprogram.bsky.social · 05/11/2025
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor. The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2. www.leadingedgesymposium.org/apply/
Candid photo of Zara Weinberg. She has short red hair, bangs and glasses. She is laughing.
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 24/10/2025
We love this!! ❤️ #UCSFProud
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Trends in Genetics @cp-trendsgenetics.bsky.social · 20/10/2025
Happy World CRISPR Day! The CRISPR revolution began with genome editing, but the platform has evolved into a versatile molecular toolkit with wide-ranging applications. The current issue of TiG includes a Review of these applications. Check it out! www.cell.com/trends/genet...
cell.com
Expanding horizons of CRISPR applications beyond genome editing
Clustered regularly interspaced short palindromic repeats (CRISPR) technologies have rapidly evolved beyond genome editing, transforming fields such as molecular diagnostics, biosensing, transcription...
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 16/10/2025
Join us today, 10/16, for Getting to Patients! Dr. Claire Clelland will share “Developing CRISPR gene therapy for C9orf72 FTD/ALS: the path ahead to clinic” with Special Guests and perspectives from a family with the C9orf72 gene tiny.ucsf.edu/14kshU @ucsfsurgery.bsky.social
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 10/10/2025
Congrats to Kyle Cromer, PhD, on receiving an NIH Director’s New Innovator Award! Dr. Cromer is working on better treatments for sickle cell disease by trying to help the bone marrow produce more healthy red blood cells. 🧬 #UCSFProud www.ucsf.edu/news/2025/10...
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 10/10/2025
A new imaging technique and single-cell sequencing reveal a deeper understanding of ovarian aging. @ucsanfrancisco.bsky.social & @czbiohub.bsky.social study could be key to strategies for extended fertility and healthier aging. www.ucsf.edu/news/2025/10...
ucsf.edu
Why Does Female Fertility Decline So Fast? The Key Is the Ovary
New research shows that the surrounding cells and tissues of the ovary play a crucial role in how eggs mature and how quickly fertility wanes.
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 08/10/2025
For #StemCellAwarenessDay, a look at a human neuron grown from stem cells, captured by Dr. Yonatan Perez, a Kriegstein Lab postdoc alum. This work could inform therapies for neurological disorders and brain regeneration.
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 26/09/2025
Congratulations to our Broad Center members (Bruce Conklin, Tippi MacKenzie, Jingjing Li, Benoit Bruneau, and Holger Willenbring) and colleagues on their newly awarded CIRM Discovery (DISC0) grants!
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 24/09/2025
From cloudy mornings to golden sunsets—the UCSF Broad Stem Cell Center always has a view worth sharing. 🌿☀️ Thanks to Lael and Cassie from the IRM Admin Team for these shots! #UCSF #Dolby #KarlTheFog #OfficeViews #CampusViews #GoldenHour
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 09/09/2025
Congratulations, Tomasz Nowakowski, PhD! 🧬🧠✨ #UCSFProud
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University of California @uofcalifornia.bsky.social · 17/07/2025
The University of California provides transformative educational opportunities, life-saving health care and research that moves our state forward and powers our economy. Stand with UC for the future of California: bit.ly/46LvcMo youtu.be/OpvhTJtxF5o?...
youtu.be
The University of California: Boldly Californian
YouTube video by University of California
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 12/08/2025
Congrats to Lilian Gomes de Oliveira, PhD, who joins the 2025 class of Pew scholars and fellows! As a Pew Latin American Fellow, Lilian will explore how the Zika virus disrupts cerebral cortex development during the second trimester of pregnancy. Learn More: www.pew.org/en/about/new...
The Pew Charitable Trusts today announced the 2025 class of the Pew Latin American Fellows Program in the Biomedical Sciences.

The 10 postdoctoral fellows from five Latin American countries—Argentina, Bolivia, Brazil, Chile, and Mexico—will receive two years of funding to conduct research in laboratories throughout the United States. They will work under the mentorship of prominent biomedical scientists, including alumni from the Latin American fellows program and the Pew Scholars Program in the Biomedical Sciences.

“Scientific exchange and collaboration foster new discoveries that help advance human health for all,” said Donna Frisby-Greenwood, Pew’s senior vice president for Philadelphia and scientific advancement. “Pew is proud to support this outstanding group of young researchers, whose pursuits will help pave the way to biomedicine’s future.”

Fellows who choose to return to Latin America to launch their own research labs will receive additional funding from Pew. Nearly 70% of program participants have taken this path, which has helped cultivate a robust biomedical research community in Latin America.

Scientists in the 2025 class are exploring a range of research topics, including examining how brain tumors evolve to resist therapy, the ways in which immune cells reduce chronic pain during pregnancy, and how the nervous system rebuilds after injury.
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 12/08/2025
New from the Cromer Lab detailing methods for achieving high-efficiency CRISPR-based genome editing in primary hematopoietic stem and progenitor cells (HSPCs). Discover more @cp-starprotocols.bsky.social | star-protocols.cell.com/protocols/4394
What’s the story?
The protocol provides step-by-step methods to efficiently and safely edit the genome in human hematopoietic stem cells (HSCs) using the CRISPR/AAV editing platform, from preparing the repair template, maintaining the HSCs, and evaluating the editing outcomes.

What did they learn?
The researchers demonstrated that using their CRISPR‑Cas9 plus AAV protocol on human HSCs leads to highly efficient genome editing and robust production of functional erythroid cells in vitro.

What’s the impact?
The piece, published in STAR Protocols journal, provides a reliable, efficient way to edit human HSCs while keeping them healthy, paving the way for developing new genome editing therapies for blood disorders.
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Dr. Elizabeth Crouch @elizabethcrouch.bsky.social · 01/08/2025
So proud of Kaylee who won a #GordonConference Travel Award! 🥇 🤩 Congrats to @brisapalikuqilab.bsky.social for a fantastic #GRS and Profs Karina Yaniv and Anne Eichmann for an outstanding #Angiogenesis conference @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 08/08/2025
Congratulations, Jaela Caston and @elizabethcrouch.bsky.social!! We’re #UCSFProud to celebrate you as 2025 Gilliam Fellow & Advisor 🎉 @ucsanfrancisco.bsky.social www.hhmi.org/programs/gil...
The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.

Through this program, HHMI supports both graduate students and their faculty thesis advisors. Fellows receive up to three years of PhD dissertation support alongside numerous opportunities to connect with peers, program alumni, and HHMI scientists at every career stage. Both students and advisors benefit from tailored professional development programming and become part of HHMI’s vibrant scientific community.
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 04/08/2025
🧬 The gene therapy landscape for sickle cell is evolving—join the UCSF Sickle Cell Center of Excellence for a powerful virtual town hall with Dr. Mark Walters, an expert in sickle cell and cell/gene therapy. This session is perfect for patients, caregivers, healthcare professionals, and advocates.
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California Institute for Regenerative Medicine (CIRM) @cirmnews.bsky.social · 30/07/2025
Thank you to all the incredible trainees, program directors, patient advocates, and inspiring speakers who joined us for the 2025 #CIRMTraineeConference! We’re grateful for the insights you shared and the community we continue to build together in advancing #RegenerativeMedicine. #BlueskyBiotech
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 29/07/2025
New in @natneuro.nature.com: Astrocyte fate isn’t hardwired — it’s shaped by where they grow up. Local neuron signals — not just where they come from — shape their identity. A key step toward understanding brain health and developing new therapies. rdcu.be/eyoIX #NewResearch
rdcu.be
Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals
Nature Neuroscience - The relative contribution of intrinsic and extrinsic factors to astrocyte heterogeneity is unknown. Using heterotropic transplantation of septal astrocytes with distinct...
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 28/07/2025
🎧 Don’t miss this podcast with Dr. Tippi MacKenzie, Broad Center Director, on in utero therapies & the future of regenerative medicine. 📍19:40: vision for the Center → discover, engineer, heal. 🔗 bit.ly/46qjYgi #UCSF #StemCells #FetalSurgery #GeneTherapy #GenomeEditing #DiscoverEngineerHeal
bit.ly
Curing Genetic Disease Before Life Begins with Tippi MacKenzie
Fetal surgeon Tippi MacKenzie on curing genetic disease before birth using in utero therapy.
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Innovative Genomics Institute @innovativegenomics.bsky.social · 24/07/2025
Did you know that the illustrations in our resources like CRISPRpedia are free to use for non-commercial, educational purposes? Check out our Science x Art page to see a selection of work from our designers & artists. Tag us to show us how you're using them! innovativegenomics.org/science-x-art/ 🧬🎨
innovativegenomics.org
Science x Art
Science x Art - Innovative Genomics Institute (IGI)
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Society for Neuroscience @sfn.org · 22/07/2025
It's #WorldBrainDay! The brain controls everything that makes life possible. Scientific research provides the tools and knowledge needed to protect, restore, and enhance brain health for all. Are you a #neurowiz? Take this short quiz to find out: vist.ly/3yr5j
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UCSF Broad Stem Cell Center @ucsfstemcell.bsky.social · 18/07/2025
Why Is Discovery Research So Important? Broad Center member Grae Davis unpacks how big breakthroughs happen and why public understanding of science matters: magazine.ucsf.edu/why-discover...
magazine.ucsf.edu
Why Is Discovery Research So Important?
Neuroscientist Grae Davis, PhD, unpacks why public understanding of science matters.
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Dr. Elizabeth Crouch @elizabethcrouch.bsky.social · 16/07/2025
A full circle ⭕️ moment interviewing @ameliecollins79 . Dr. Collins was my fellow during my #neonatology sub-I. Fascinating #hsc work (the mother cell of #immunology!) ✅it out and her 😍publication: pubmed.ncbi.nlm.nih.gov/38428422/ @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social
pubmed.ncbi.nlm.nih.gov
Maternal inflammation regulates fetal emergency myelopoiesis - PubMed
Neonates are highly susceptible to inflammation and infection. Here, we investigate how late fetal liver (FL) mouse hematopoietic stem and progenitor cells (HSPCs) respond to inflammation, testing the...
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California Institute for Regenerative Medicine (CIRM) @cirmnews.bsky.social · 12/06/2025
🚨 REMINDER: Prospective DISC4 applicants, the Pre-Submission Form deadline is June 16 at 2 PM. The DISC4 Awards support large, cross-disciplinary teams working on innovative ways to understand and treat human disease. Learn more at www.cirm.ca.gov/disc4/.
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