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Xtremo-Devo Lab @ WMU

@xtremo-devo-lab.bsky.social
279 followers 1.3K following 10 posts

Eco-Evo-Devo of killifish & kin. 🐟 Uncovering the 🧬 blueprints for life in extreme environments. Ex luto surgimus. #EcoEvoDevo #Killifish #WMU andrewwt.github.io/xtremodevo-lab

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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 28/09/2026
#fish 🐟 🐠 researchers and PIs of tomorrow! We like to sponsor you for an Ecology, Evolution and Behavior (EEB) Presidential #Postdoc Fellowship application @michiganstateu.bsky.social. Applications due Nov 1, so get in touch soom! #EndlessFishMostBeautiful www.fishevodevogeno.org Pls repost!
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Xtremo-Devo Lab @ WMU @xtremo-devo-lab.bsky.social · 25/09/2026
Last day to register for #AQMHD2026! It's going to be a fun time in Woods Hole!
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Xtremo-Devo Lab @ WMU @xtremo-devo-lab.bsky.social · 23/09/2026
Only 2 days left to join us in MBL! #Zebrafish #Gar #Killifish #Medaka #Stickleback #Xiphophorus #Lamprey #Xenopus #Cephalopod #Squid #Hydra #Aplysia #Nematostella #Tunicate #SeaUrchin #Planarian #Ctenophore #Ciona #Echinoderm #Aiptasia #Coral #ComparativeBiology
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Xtremo-Devo Lab @ WMU @xtremo-devo-lab.bsky.social · 27/08/2026
Hope to see you there!
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aqmhd2026.bsky.social @aqmhd2026.bsky.social · 11/08/2026
📣 Registration is now OPEN for #AQMHD2026! 🐟 12th Aquatic Models of Human Disease Conference 📍 Marine Biological Laboratory, Woods Hole, MA 📅 October 17–21, 2026 We’re also extending the abstract deadline to Aug. 17, 2026! More info: aqmhd.org
aqmhd.org
AQMHD 2026 | Aquatic Models of Human Disease
12th Aquatic Models of Human Disease Conference, October 17–21, 2026, Marine Biological Laboratory, Woods Hole, MA
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aqmhd2026.bsky.social @aqmhd2026.bsky.social · 04/08/2026
#AQMHD2026 Registration will open soon. Please repost and stay tuned!
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Xtremo-Devo Lab @ WMU @xtremo-devo-lab.bsky.social · 30/07/2026
So grateful to be part of this awesome project!
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Xtremo-Devo Lab @ WMU @xtremo-devo-lab.bsky.social · 30/07/2026
Spread the word!
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Xtremo-Devo Lab @ WMU @xtremo-devo-lab.bsky.social · 27/07/2026
My favorite conference! Hope to see you in Woods Hole!
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Xtremo-Devo Lab @ WMU @xtremo-devo-lab.bsky.social · 23/07/2026
Excited to see what’s next!
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aqmhd2026.bsky.social @aqmhd2026.bsky.social · 21/07/2026
📣 Abstract submission is OPEN for #AQMHD2026! 🐟🦑🪸 Join us Oct 17–21, 2026 at MBL in Woods Hole, MA for the 12th Aquatic Models of Human Disease Conference. Submit by Aug 10, 2026: docs.google.com/forms/d/e/1F...
docs.google.com
AQMHD 2026 Abstract Submission
12th Aquatic Models of Human Disease Conference October 17–21, 2026 | Marine Biological Laboratory, Woods Hole, Massachusetts Submit one form per abstract. Complete all required fields and paste the ...
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aqmhd2026.bsky.social @aqmhd2026.bsky.social · 17/07/2026
Hello AQMHD community! The “final” #AQMHD2026 program is live—final, that is, until we add talks selected from submitted abstracts! 🐟🧬 Join us Oct. 17–21 at the Marine Biological Laboratory in Woods Hole, MA. Abstract submission opens soon—watch for details next week! aqmhd.org/program.html
aqmhd.org
Final Program | AQMHD 2026
Final program for the 12th Aquatic Models of Human Disease Conference
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Mike Dorrity @mwdorr.bsky.social · 19/06/2026
First pre-print from the lab, a collaborative effort led by Jess Bourn @bournsupremacy.bsky.social, a fantastic PhD in my group. We resolve a key problem in development + evolution: how do we quantify heterochrony and link temporal variation to phenotype? www.biorxiv.org/content/10.6...
biorxiv.org
Quantitative mapping of heterochrony to species-specific phenotypes
The genetic program of animal development is conserved, but its rate of execution varies across species. Heterochrony, shifts in the relative timing of developmental events, generates phenotypic varia...
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Zebrafish Rock! @zebrafishrock.bsky.social · 10/05/2026
Very cool work from the Teleost zoo! #TeleostTalk 🧪
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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 08/03/2026
#OTD 10 years ago we published the spotted #gar genome. 600+ citations later, we are proud of its impact on vertebrate genomics. @jpostlethwait.bsky.social Check out the new assemblies generated with @vertebrategenomes.bsky.social www.ncbi.nlm.nih.gov/datasets/gen... #EndlessFishMostBeautiful
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Xtremo-Devo Lab @ WMU @xtremo-devo-lab.bsky.social · 04/03/2026
Please repost and share! We look forward to seeing you there!
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Trends in Genetics @cp-trendsgenetics.bsky.social · 23/02/2026
"Medaka: A novel model for analyzing genome-environment interactions" by Kiyoshi Naruse & colleagues "Endemic to habitats spanning from 4 to 40°C and varying salinities, [medaka] combines broad ecological adaptability with experimental tractability." Read more: authors.elsevier.com/sd/article/S...
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Mike Inouye @mikeinouye.bsky.social · 12/02/2026
Super cool work on medaka by @ewanbirney.bsky.social and colleagues www.cell.com/cell-genomic... Includes an excellent summary from Ewan via linkedin... and I maintain that 'humans aren't special' 😊 www.linkedin.com/pulse/little...
linkedin.com
The little fish that could.
Today sees the publication of a long awaited paper from my group. This has been.
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Igor Schneider @ischneider.bsky.social · 22/01/2026
And it's out indeed! Huge congrats to @josanesousa.bsky.social, @gabrielalima19.bsky.social, @perezlouise.bsky.social & Hannah Schof! A true tour-de-force that highlights how emerging model systems can shed new light on long-standing macro-evolutionary questions. Go #axolotl, #polypterus #zebrafish!
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Arjun Krishnan @compbiologist.bsky.social · 06/01/2026
Our Perspective article on Computational Strategies for Cross-Species Knowledge Transfer is now published in @natmethods.nature.com! This was a collab b/w @krishnanlab.bsky.social & @fishevodevogeno.bsky.social, led by the amazing Hao Yuan @yhbioinfo.bsky.social. 🧵 www.nature.com/articles/s41...
Figure depicting the four classes of important questions that frequently arise when using research organisms to study biomedical questions and translating findings to humans. a, How to predict disease–gene or function–gene relationships across species? Diagram depicts genes in each species associating with specific functions, diseases and phenotypes. b, How to identify functionally equivalent molecular components across species? Diagram depicts finding the most equivalent gene, pathway or expression module or phenotype between species. c, How to infer perturbed molecular profiles across species? Diagram depicts gene expression in each species as a result of taking a particular perturbation like a drug. d, How to map equivalent cell types and cell states across species? Diagram depicts alignment of cell types across species. This Perspective comprehensively lays out the landscape of recent and state-of-the-art data-driven strategies, including those that leverage artificial intelligence and machine learning (ML), for answering these questions.
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Patricia Schneider @patyschneider22.bsky.social · 04/11/2025
How do four-eyed fish see above & underwater? 🌤️🌊 Our new preprint reveals how Anableps rewired its retina for dual vision- evolution at work 👁️👁️ Kudos to @perezlouise.bsky.social @josanesousa.bsky.social @keylapruett.bsky.social + team! 🔗 tinyurl.com/3a8r9xy5
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Molecular Biology and Evolution @molbioevol.bsky.social · 21/10/2025
@snbogan.bsky.social @notothentoma.bsky.social @scotthotaling.bsky.social @paulbfrandsen.bsky.social et al. explore the evolution of type III antifreeze proteins in deep sea zoarcoid fishes. 🔗 doi.org/10.1093/molbev/msaf219 #evobio #molbio
MBE | Temperature and Pressure Shaped the Evolution of Antifreeze Proteins in Polar and Deep Sea Zoarcoid Fishes
A graphic visualizing the finding by Bogan et al. that antifreeze protein (AFP) genes increased in copy number among shallow-water, polar species of Zoarcoidei fishes. Top left: Pholis gunnellus photographed by Chris Isaacs (CC-BY-NC). Top right: Cebidichthys violaceus photographed by Alex Heyman (CC0 1.0). Bottom left: Lycenchelys sp. photographed by Julien Savoie (CC BY 4.0). Bottom right: Lycodes sp. photographed by Julien Savoie (CC BY 4.0).
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Emily Troyer @fishfetisher.bsky.social · 22/10/2025
Why are some species smaller than a paperclip while others grow longer than a school bus? How is body size evolution governed in animals? Out now in @pnas.org we tackle these longstanding questions through a genetic lens using my favorite group of fishes as our model!! www.pnas.org/doi/10.1073/...
pnas.org
Parallel shifts in differential gene expression reveal convergent miniaturization in fishes | PNAS
Body size variation in vertebrates is a complex polygenic trait, tightly correlated with numerous aspects of a species’ biology, ecology, and physi...
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Parichy Lab | Dave Parichy @dparichy.bsky.social · 19/10/2025
New preprint up with collaborators Jianguo Lu, @mpodobnik.bsky.social, Uwe Irion, Braedan McCluskey, John Postlethwait and others. New Danio genomes, evolution and pigment pattern variation. Long time in the making www.biorxiv.org/content/10.1...
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Zebrafish Rock! @zebrafishrock.bsky.social · 19/10/2025
Zebrafish embryo undergoing gastrulation. Credit to Dr. Gopi Shah at EMBL. #ZebrafishZunday 🧪
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Monterey Bay Aquarium @montereybayaquarium.org · 20/10/2025
👻 G-g-ghost? Nope, s-s-snailfish! 🤍 Meet the mesmerizing new addition to our Into the Deep/En lo Profundo exhibit, rough snailfish! These ethereal charmers live in the benthic zone, a scientific term for the seafloor.
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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 02/10/2025
Congrats @liujuan.bsky.social, our very own @zzhou32.bsky.social and all co-authors! Fintastic work!
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Marc Robinson-Rechavi @marcrr.bsky.social · 03/09/2025
Update of our preprint on Inter-individual gene expression variability in fishes! We improved statistical analyses of continuous variables, and especially added machine learning on promoters which confirms cis-regulation of organ-specific expression variability. www.biorxiv.org/content/10.1...
biorxiv.org
Inter-individual gene expression variability implies stable regulation of brain-biased genes across organs
Phenotypic variation among individuals plays a key role in evolution, since variation provides the material on which natural selection can act. One important link between genetic and phenotypic variat...
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EvoDevo PanAm @evodevopanam.bsky.social · 23/07/2025
You're fin-tastic! 🐟🐠🌟🤩 Our fish community present #PASEDB2025! @nakamuralab.bsky.social @phernandez.bsky.social @patyschneider22.bsky.social @ischneider.bsky.social @xtremo-devo-lab.bsky.social @fishevodevogeno.bsky.social @homeobox.bsky.social and more! Help us to tag them
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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 23/07/2025
Our dear friend @ischneider.bsky.social receiving the Young Investigator Award from @evodevopanam.bsky.social! So incredibly deserved! #PASEDB2025 To infishity and beyond! Great work, Igor!
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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 22/07/2025
EvoDevotees, if you are at #PASEDB2025 and interested in either of these job opportunities for Fish Facility Manager or Presidential Postdoc at Michigan State U, let’s grab a coffee and chat #EndlessFishMostBeautiful @evodevopanam.bsky.social
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Igor Schneider @ischneider.bsky.social · 22/07/2025
#PanAmEvodevo2025 is about to start! Starting countdown, engines on! @fishevodevogeno.bsky.social @xtremo-devo-lab.bsky.social @patyschneider22.bsky.social
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Current Biology @currentbiology.bsky.social · 07/07/2025
Our latest issue is now live! On the cover is a species of Asian noodlefish characterized by their transparency due to the absence of red blood cells, slender bodies and scaleless skins, and a poorly ossified skeleton. www.cell.com/current-biol...
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M. Brent Hawkins @homeobox.bsky.social · 07/07/2025
We take for granted that our hands have two sides and can articulate in an endless number of ways. But what about a fish’s fin? Can a fish know something “like the back of its fin,” or have its future told with a fin palm reading? Check out this bluetorial to find out 👇🧪🧬🐟 doi.org/10.1101/2025...
Schematics depicting the dorsal and ventral sides of fins and limbs
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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 01/07/2025
The Braasch Lab @fishevodevogeno.bsky.social will soon post a position to replace manager of our *Ancient Fish Facility* at Michigan State. Looking for aquaculturist excited for unusual 🐟 species (gar, bowfin, paddlefish, polypterus) + zebrafish. Pls send candidates our way (DM or braasch@msu.edu)!
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EvoDevo PanAm @evodevopanam.bsky.social · 28/06/2025
At #PASEDB we embrace all organisms. Each one has its own evolutionary trajectory that makes life so diverse 🌈🦄 Artwork: Ximena Gutierrez Ramos and Katie Reding
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Jeff Farrell @jeffreyafarrell.bsky.social · 13/06/2025
If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)
DaniocellDesktop logo, depicting a fish on a laptop screen.
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EvoDevo PanAm @evodevopanam.bsky.social · 06/06/2025
You have so-fish-ticated taste 🐟 Fish satellite symposia speaker talks at #PASEDB Invited speaker: Andrew Thompson Organizers: @nakamuralab.bsky.social @patyschneider22.bsky.social & Joaquín Letelier Register: evodevo.wildapricot.org/event-6007396
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Prosanta Chakrabarty @prosanta.bsky.social · 06/06/2025
An (omics) perspective on the evolution of vision in deep-sea fishes reveals exceptional adaptations to life in the extreme Musilova & Cortesi 2025 Functional Ecology besjournals.onlinelibrary.wiley.com/doi/pdfdirec... #ichthyology #teamfish neat review of genetics of deep-sea vision in fishes
deep-sea adaptations have evolved independently in several groups.
Eye shape: A prominent morphological example is the evolution of an elongated tubular, barrel eye to maximize photon capture in several
deep-sea groups. Groups, where tubular eyes are common, are marked by a black square and a tubular eye scheme; groups with one/
few cases of tubular eyes but where the majority of species have a camera-type eye are marked with black dots (i.e. anglerfishes and
dragonfishes). Retina: Rod-only retinas are a common feature of many adult deep-sea fishes. In other cases, they possess the typical duplex
retina with cones (green cells) and rod cells (grey cells). Multibank: In some species, the rod cells are organized in multiple layers, forming a
multibank retina, while other deep-sea fishes have the typical vertebrate single layer. Cone/rod id: Some deep-sea fishes have photoreceptor
cells with an uncertain id that is intermediate between rods and cones due to a mismatch of the opsin and phototransduction cascade genes
(e.g. in Scopelarchidae and Evermanellidae; Aulopiformes), or thanks to the presence of transmuted cells (i.e. rod-like cones in Maurolicus
spp.; Sternoptychidae; Stomiiformes). Rhodopsins: Like other vertebrates, most lineages only have one rhodopsin (rh1) gene. Two rhodopsins
are found in pearleyes (Scopelarchidae; Aulopiformes), and hatchetfishes (Sternoptychidae, Stomiiformes), and more than three rhodopsin
genes are found in lanternfishes (Myctophiformes), spinyfins (Diretmidae), and tube-eye (Stylephoriformes). Photos (from top to bottom):
Threadfin dragonfish, Echiostoma barbatum (Stomiiformes; photo Zuzana Musilova); pearleye, Benthalbella sp. (Aulopiformes; photo Zuzana
Konvičková); and silver spinyfin, Diretmus argenteus (Trachichthyiformes; photo Vít Kaufman). Based on data from Collin and Partridge (1996),
De Busserolles et al. (2017), De Busserolles et al. (2020), Lupše et al. (2021) and Musilova, Cortesi, et al. (2
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SHOAL @shoalorg.bsky.social · 04/06/2025
🐟 Thanks to everyone who joined our Killifish Webinar! We chatted with four expert voices about the brilliant killifish conservation work they have been doing in the Mediterranean Basin #freshwater ICYMI it's now available to watch again on YouTube 👇 buff.ly/R4wxOcY
Photograph of a grey and green fish, with a green box inside which is a green play button.
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Fredrik Jutfelt 🐠 @jutfelt.bsky.social · 03/06/2025
Sturgeon surprise! 🧜‍♀️
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Xtremo-Devo Lab @ WMU @xtremo-devo-lab.bsky.social · 01/06/2025
Gotta tag some #library people! @jacquelinethompson.bsky.social
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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 30/05/2025
Backflippin’ feeding action! #Paddlefishing #Polyodon #EndlessPaddlefishMostBeautiful Le fin!
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Emily Troyer @fishfetisher.bsky.social · 30/05/2025
Incredible morphological convergence!! #Evol2025
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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 22/05/2025
Hyperactive #Polyodon - one week old #Paddlefishing #EndlessFishMostBeautiful
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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 24/05/2025
#Paddlefishing #Polyodon #EndlessFishMostBeautiful
Paddlefish 8 days post fertilization
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EvoDevo PanAm @evodevopanam.bsky.social · 22/05/2025
😅🤩Fish Community!! We are happy to announce our amazing lineup for the Fish Satellite Symposium at #PASEDB2025 #evodevo 🐠🐟🐡 @homeobox.bsky.social @fishevodevogeno.bsky.social Organizers @nakamuralab.bsky.social @patyschneider22.bsky.social & Joaquín Letelier
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#SingleCell preprints @prepub-singlecell.bsky.social · 16/05/2025
Empowering medaka fish biology with versatile genomic resources in MedakaBase #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.1101/202…
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EMBL-EBI @ebi.embl.org · 13/05/2025
Heart disease is the world’s leading killer, and tackling it demands decoding the multi-gene networks driving disease progression 🫀 Learn how researchers used Medaka fish plus high-throughput heartbeat imaging to build a biomarker toolkit for early screening. www.nature.com/articles/s41...
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Braasch Lab @ Michigan State University @fishevodevogeno.bsky.social · 20/05/2025
#Paddlefishing #Polyodon #EndlessFishMostBeautiful
Paddlefish embryos 4 days old
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