iiinova — where your digital self keeps evolving

Reposted by Jeff Farrell

Nick Desnoyer @nickdesnoyer.bsky.social · 27/07/2026

So honored to receive the @socdevbio.bsky.social SciCom award and to share my work with the wonderful people in this community! This #2026SDB conference was a celebration of biodiversity 🧵

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Reposted by Jeff Farrell

Mike Piacentino @mikepiacentino.bsky.social · 21/07/2026

Come join us! 🔬🐣 The Piacentino Lab at Johns Hopkins @hopkinsmedicine.bsky.social is recruiting a postdoc to study membrane lipids, cell migration, and invasion in neural crest and embryonic models! @socdevbio.bsky.social @ascbiology.bsky.social #devbiol #cellbio #lipids

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Reposted by Jeff Farrell

Society for Developmental Biology @socdevbio.bsky.social · 14/07/2026

✨Jeffrey Farrell @jeffreyafarrell.bsky.social is a Stadtman Investigator at the NIH. He has led seminal work constructing single-cell RNAseq atlases for entire embryos using zebrafish. We are excited to host Jeffrey at the #2026SDB in Las Vegas! 🔬

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Jeff Farrell @jeffreyafarrell.bsky.social · 01/05/2026

Hard to say goodbye today to the lab’s first postdoc, but so excited to see what @abhinavsur.bsky.social will do in his new lab at U Arizona. We’re going to miss you deeply over here. Safe travels and knock em dead.

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Jeff Farrell @jeffreyafarrell.bsky.social · 27/02/2026

Apply to this course!!! The deadline is soon, but if you are considering using zebrafish for the first time in your career, this is an incredible opportunity. I took this in 2013, and it changed my career - and started several friendships and scientific relationships that persist to today!

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Reposted by Jeff Farrell

Roberto Mayor Lab @mayorlab.bsky.social · 08/02/2026

It’s a real honour to receive the Viktor Hamburger Outstanding Educator Prize from the SDB. Teaching is one of the most rewarding parts of my life. Thanks to the SDB and the hundreds of students and faculty at the Quintay course who have made it such a joy.

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Jeff Farrell @jeffreyafarrell.bsky.social · 05/02/2026

Oh man! What a crazy honor to receive this award from SDB!! I love being a part of SDB so much - it has led to so many awesome ideas, collaborations, and friendships over the last 13 years, so this is really exciting. Looking forward to seeing you all at the meeting. Thank you, SDB!!!

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Jeff Farrell @jeffreyafarrell.bsky.social · 29/01/2026

I’m recruiting new members to the Farrell Lab this summer. We will have space for 1 postdoc (since Abhinav is leaving to start his own lab at U Arizona!!) and 2 postbacs, since my current two will leave for PhD programs at the end of the summer. More details in thread:

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Jeff Farrell @jeffreyafarrell.bsky.social · 09/01/2026

Happy New Year! NEW LAB PREPRINT testing how best4+ intestinal epithelial cells develop! best4+ cells are conserved across vertebrates and altered in IBD & colorectal cancer. But they were first molecularly IDed in 2019. We barely know anything about them yet! What do they do?? HOW DO THEY GET MADE?

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Reposted by Jeff Farrell

Shawn Burgess @burgesslab.bsky.social · 15/08/2025

#zebrafish genome update, our T2T assembly of the inbred strain of AB (M-AB) generated by my buddy Nori Sakai has now been released at NCBI and will be a second reference genome for zebrafish (GRCz12ab):

ncbi.nlm.nih.gov

JBQAYU000000000.1 Danio rerio :: NCBI

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Jeff Farrell @jeffreyafarrell.bsky.social · 31/07/2025

Ok, friends! If you’re a Daniocell user, it’s now available again outside of the NIH. Very sorry for any inconvenience this posed for any of you and thanks for your patience. We’re taking additional steps to hopefully prevent similar outages in the future. Happy surfing 🎣

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Jeff Farrell @jeffreyafarrell.bsky.social · 29/07/2025

Hey friends - Daniocell is experiencing a temporary outage right now. The NICHD server it is hosted on got dropped from the NIH’s firewall list & so currently can’t be accessed outside the NIH. The relevant IT teams are working to resolve it. Sorry for any inconvenience. It’ll be back soon!!

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Jeff Farrell @jeffreyafarrell.bsky.social · 29/07/2025

It was super fun working on this interview with Saanjbati Adhikari about my path during my scientific training.

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Reposted by Jeff Farrell

Rebecca D. Burdine, PhD @rburdine1.bsky.social · 22/06/2025

@mads100tist.bsky.social calling attention to the awesomeness of #zebrafish #devbio and community. #SDB

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Jeff Farrell @jeffreyafarrell.bsky.social · 13/06/2025

If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)

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Reposted by Jeff Farrell

James Gagnon @james-gagnon.bsky.social · 02/06/2025

To dissect the gene regulatory networks used to build organisms, we need Perturb-seq-like tools that work in whole animals. For this purpose, we developed MIC-Drop-seq, a tool that couples high-throughput CRISPR in zebrafish embryos with single-cell RNAseq. www.biorxiv.org/content/10.1...

biorxiv.org

MIC-Drop-seq: Scalable single-cell phenotyping of mutant vertebrate embryos

Pooled perturbation screens can reveal cellular regulatory networks, yet scaling these techniques for large-scale screens in animals remains challenging. To address this, we developed MIC-Drop-seq, wh...

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Reposted by Jeff Farrell

Kristen Kwan @blockintheback.bsky.social · 21/05/2025

It was so awesome to have @jeffreyafarrell.bsky.social here to give a departmental seminar today!!

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Reposted by Jeff Farrell

Todd Macfarlan @toddmacfarlan.bsky.social · 29/04/2025

I am looking for postdocs to join my group at NIH. Are you interested in Development, Evolution, Genetics, Genomics, and Human health? Please apply! www.training.nih.gov/jobs/pdf-mb-...

training.nih.gov

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Reposted by Jeff Farrell

Alex Chesler @alexchesler.bsky.social · 23/04/2025

An example of what we in the NIH Intramural program can accomplish. Excited to share our latest paper in close collaboration with Nick Ryba's group. We examined how inflammation transforms representation in somatosensory neurons to cause pain. Lots of surprises here: www.nature.com/articles/s41...

nature.com

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Reposted by Jeff Farrell

Zebrafish Rock! @zebrafishrock.bsky.social · 16/04/2025

“These findings support the use of zebrafish as a useful comparative model for studying the meninges, provide a foundational description for future zebrafish meningeal research” New work from @biomarina-vg.bsky.social & Weinstein Lab at NIH 🐟

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Reposted by Jeff Farrell

Katherine W. Rogers @katwrog.bsky.social · 21/04/2025

Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...

biorxiv.org

An optogenetic toolkit for robust activation of FGF, BMP, and Nodal signaling in zebrafish

Cell signaling regulates a wide range of biological processes including development, homeostasis, and disease. Accessible technologies to precisely manipulate signaling have important applications in ...

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Jeff Farrell @jeffreyafarrell.bsky.social · 15/12/2024

If you want to make it easy for editors to find reviewers for your manuscript, pre-print it so that prospective reviewers can quickly scan through it to make sure it's within their expertise and not going to be a slog. I am 5x more likely to accept if I can spend 5 minutes looking at the figs.

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Reposted by Jeff Farrell

Pauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 13/12/2024

The life of each of us began when a sperm and an egg came together. But what happens at a molecular level? Our latest work in Cell led by @vdeneke.bsky.social & Andreas Blaha reveals a conserved fertilization complex that bridges sperm and egg in vertebrates! (1/11) www.cell.com/cell/fulltex...

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Jeff Farrell @jeffreyafarrell.bsky.social · 26/11/2024

Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)

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Jeff Farrell @jeffreyafarrell.bsky.social · 22/11/2024

So happy that we got to work with Jamie a little bit on this project. Congrats to Andy Sposato on her awesome work!!!!

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Jeff Farrell @jeffreyafarrell.bsky.social · 23/08/2024

NICHD Intramural (Bethesda, MD) is having a faculty search this year, focused on neural development. Apply by Sep 30 via two routes (Stadtman + direct, see thread). Details: (1/5)

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Jeff Farrell @jeffreyafarrell.bsky.social · 05/03/2024

Looking forward to seeing everyone at #TAGC24 and hearing so much incredible new science!

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Jeff Farrell @jeffreyafarrell.bsky.social · 27/10/2023

In my usual fashion, extremely slow to post something, but thanks so much for hosting me for an amazing visit to Penn, @bushranraj. Had so much fun visiting with you, your colleagues, and your awesome lab members!

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Jeff Farrell @jeffreyafarrell.bsky.social · 22/03/2023

The lab’s first preprint! Super excited to share our work profiling cell types and gene expression cascades during zebrafish development & release a corresponding website (Daniocell) so you can dig through the data too! (1/10)

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Jeff Farrell @jeffreyafarrell.bsky.social · 11/10/2022

Happy #NationalComingOutDay to all my queer and questioning scientists! A journey that I began 23 years ago, but always remains ongoing. Thankfully, developmental biology has been a truly supportive career and always embraced me for who I am. (1/3)

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Jeff Farrell @jeffreyafarrell.bsky.social · 06/10/2022

#AQMHD2022 Genomic Tools Workshop (here introduced by @FishEvoDevoGeno) today was some awesome science. So exciting to get to participate.

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Jeff Farrell @jeffreyafarrell.bsky.social · 20/09/2022

Amazing first day of #GfE2022 (here introduced by organizers @WalentekLab and @RosiFeistel). I learned so much already on day one, and there are so many cool people here to meet. Come chat with me!!

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Jeff Farrell @jeffreyafarrell.bsky.social · 19/07/2022

What a day! Congrats to @abhinav_sur on CRUSHING IT today giving the first conference presentation from a lab trainee!! Come be our colleague! We’re recruiting so get in touch. #SDB2022

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Jeff Farrell @jeffreyafarrell.bsky.social · 15/07/2022

So excited to catch up with you wonderful dev biologists at #SDB2022! Hope to see you at @abhinav_sur's talk about our new zebrafish scRNAseq data, shared gene modules, and uncharacterized cell types. And so much more he can't fit in the talk - chat with him after!

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Jeff Farrell @jeffreyafarrell.bsky.social · 08/07/2022

Very bittersweet see Eric and Jeremy off to their next steps this week after two awesome years as post-bacs in the lab. So proud of everything they accomplished and can't wait to see what they do next. Especially looking forward to finding out which lab Eric joins @WashUDevBio.

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Jeff Farrell @jeffreyafarrell.bsky.social · 26/06/2022

Huge congratulations to @abhinav_sur on winning a poster award at #IZFC2022. And just so we’re clear, it was an award for scientific content, not its incredible, record setting size. #proudpi

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Jeff Farrell @jeffreyafarrell.bsky.social · 23/06/2022

Wow! What a great first day of #IZFC2022. Amazing to see old zebrafish friends and to make new ones! DM me if you want to say hi or grab a meal or drink together — to catch up or if you’re potentially interested in the lab — we’re recruiting for funded positions at all levels!

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Jeff Farrell @jeffreyafarrell.bsky.social · 14/07/2021

The Farrell lab is looking for a post-doc to join the lab in 2022. Are you at #SDB2021 / #2021SDB and finishing your graduate studies? If you’re interested in our work (), reach out so I can come learn about yours and meet you!

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Jeff Farrell @jeffreyafarrell.bsky.social · 26/04/2021

Congratulations to @YiqunWang3, newly minted Dr. Wang! So proud of you today - your accomplishments and what a strong scientist you've become - and so thankful for so many excellent years working together. It was a major highlight of my post-doc. Cannot wait to see what's next!

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Jeff Farrell @jeffreyafarrell.bsky.social · 01/12/2020

A compelling reason to document your software well is that someday the person reading that documentation to figure out how a function works will be YOURSELF. Is this PI brain or 2020 brain?

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Jeff Farrell @jeffreyafarrell.bsky.social · 20/11/2020

Regardless of what gets published, I'm very thankful for the incredible female mentors that I've had during my career, both formal (Barbara Panning, Aviv Regev) and informal (@PauliGroup, @Juliano_Lab) who have all been crucial for my growth as a scientist.

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Jeff Farrell @jeffreyafarrell.bsky.social · 21/10/2020

NICHD Intramural Program is hiring a tenure-track investigator this year! Looking for innovative developmental biology -- any organism, any question.

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Jeff Farrell @jeffreyafarrell.bsky.social · 08/07/2020

As usual, day one of #2020SDB and I already have science envy where I briefly wonder if I should just scrap everything and start doing new work inspired by the awesome stuff I just saw. Great session on imaging approaches in dev bio @radikes and @dave_matus!

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Jeff Farrell @jeffreyafarrell.bsky.social · 03/03/2020

Did not expect that the most emotionally powerful experience (so far) of opening a lab was going to be seeing zebrafish embryos glowing under the microscope after being injected with a new transgenesis construct and feeling that we've really made something new here.

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Jeff Farrell @jeffreyafarrell.bsky.social · 24/07/2019

Farrell lab opens Jan 2020 @ NICHD w/ fully funded positions for creative, motivated postdocs, students & postbacs to study zebrafish development (cell fate, genetics of differentiation, embryonic DNA damage w/ scRNAseq, imaging & genetics) #ZebrafishJobs

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Jeff Farrell @jeffreyafarrell.bsky.social · 24/06/2019

This weekend, celebrated my PhD mentor Pat O’Farrell’s 70th birthday with most of the rest of the former members of the O’Farrell lab. We were all thankful to be shaped by his curiosity, passion, rigor, and generosity. He gives us all a high bar to live up to.

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