McArdle researcher Renee King, PhD, CCC-SLP, has been awarded a prestigious NIH Pathway to Independence Award (K99/R00) from the National Institute on Deafness and Other Communication Disorders. Dr. K...

Leukemia predisposition–linked hematopoietic transcription factors mediate inflammation sensing by a progenitor cell genome.

The UW-Madison Office of the Provost has announced that McArdle Professor Wei Xu is one of 14 UW-Madison professors to receive the 2025 Vilas Mid-Career Investigator Award. This prestigious award reco...

Most phenotype-associated genetic variants map to noncoding regulatory regions of the human genome, but their mechanisms remain elusive in most cases. We developed a highly efficient strategy, Perturb...

McArdle alum Tim Schedl, PhD, has been elected as a fellow of the American Association for the Advancement of Science (AAAS). AAAS, the world’s largest general scientific society, has presented this h...

Elaine DzierzakDrs. Elaine Dzierzak and Anna Bigas recently edited a special collection for Experimental Hematology entitled “Making blood: mechanisms of early hematopoietic development” [1]. This is ...

Itkin et al. identify a role for Fli-1 in hematopoietic stem cell activation during regenerative hematopoiesis. They show that Fli-1 coordinates hematopoietic stem cells to stimulate niche-derived Not...

The hematopoietic system is highly regenerative and is organized hierarchically with hematopoietic stem cells (HSCs) sitting at the apex. Despite being some of the most widely studied stem cells, ques...

CD74 signaling drives inflammation and differentiation defects in hematopoietic stem and progenitor cells in RUNX1-familial platelet disorder.

An mRNA-encoded, dominant-negative inhibitor of RUNX1 exhibits preclinical efficacy in models of ocular diseases.