Neurons in the brain are often many synapses away from motoneurons, yet if a movement results in error, each distant neuron needs a teacher that considers its specific contribution to production of th...

Prediction without understanding sustained astronomy through a thousand years of epicycles. Artificial intelligence is now offering neuroscience the same deal.

Madduri et al. introduce a computational framework grounded in control and game theory to model co-adaptation between users and decoders in neural interfaces. This framework enables a principled desig...

A wealth of evidence supports the view that neural manifolds are real and useful, even if they may not solve the age-old mind-body problem.

Distinct spinal and cortical pathways coordinate muscle synergies and fine control to support primate dexterous hand movements.

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Spinal cord injury (SCI) results in profound motor impairment for approximately 20 million people worldwide. Regaining hand use is one of their highest priorities. Interestingly, even severely affecte...

Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr.

Teaching chatbots to say “I don’t know” could curb hallucinations. It could also break AI’s business model

The acquisition of novel muscle activity patterns is a key aspect of motor skill learning, which can be seen, for example, when beginner musicians learn new guitar or piano chords. To study this proce...

Recent advances in neuroscience have revealed how neural population activity underlying behavior can be well described by topological objects called neural manifolds. Understanding how nature, nurture...

Loss of hand function after spinal cord injury (SCI) significantly impairs independence and quality of life. Although residual muscle activity recorded on the skin can provide intuitive control signal...

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In an internet age when a viral sensationalist story gains far more traction than a nuanced and balanced discussion, we have become used to some politicians, media and web-based influencers bending th...

A brain-to-voice neuroprosthesis enables a man with amyotrophic lateral sclerosis to synthesize his voice in real time by decoding neural activity, demonstrating the potential of brain–computer interfaces to enable people with paralysis to speak intelligibly and expressively.

Stephen Bradley, a GP, wants his computer to work (doi:10.1136/bmj.q1171).1 He wants artificial intelligence (AI) to help make mundane and sometimes complex tasks easier. When was a drug started, why,...

Recent studies implicate the immune system and a herpes virus as potential contributors to development of the disease.

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