SeqHub is a platform for exploring, annotating, and sharing biological sequences.

Plasmids in bacteria and extrachromosomal DNA in cancer both generate copy-number variation, alter gene expression and promote rapid adaptation. In this Perspective, Shaw and Henssen explore their sha...

Protists play important roles in food chains and symbioses in soil and aquatic environments, displaying an enormous morphological and functional diversity[1][1],[2][2]. While most commonly found proti...

The Cooperative National Geologic Map is an interactive tool that builds on both cutting-edge technology and decades of mapping by geoscientists.

With great interest I am watching the creation of OpenRxiv ( an experimental project for BioRxiv and MedRxiv. My humble wish is that they move quickly to destroy the for-profit publishing indu…

A growing body of evidence indicates that factors such as rising temperatures and extreme weather are contributing to what some researchers have called “the slow pandemic.”

Generative genome design models can now produce previously unobserved genome-length sequences, but assessing their capabilities is complicated by limitations in functional prediction. The ability to e...

Archaea and bacteria routinely live side by side in microbial communities and must interact at least on occasion. Whether such cross-Domain interactions are dominated by mutual disregard, co-operation...

Nature Ecology & Evolution - Citizen science platforms must mitigate against the threat of generative AI

In Streptomyces spp., a conserved biosynthetic gene megacluster produces an arsenal of distinct antimicrobials that converge on bacterial biotin biosynthesis as a naturally evolved combination therapy...

While methods exist to indirectly quantify the metabolism of biological systems, directly measuring metabolic rates in living samples remains chall...

Abstract. Ammonia-oxidizing archaea (AOA) have repeatedly been detected with molecular methods on human skin, yet their persistence, physiological traits,

Over the last thirteen years, bioRxiv and medRxiv have grown into widely used infrastructure for rapid research sharing in biology and medicine. The reliability and researcher-first values that have d...

Resolving early steps in how hosts and microbes unite in novel endosymbiosis is critical for understanding key evolutionary innovations and ecosystem functions. Montoya et al. reveal how mobile geneti...

AbstractSummary. Phylogenetic trees are ubiquitous and central to biology, but most published trees are available only as visual diagrams and not in the ma

AbstractMotivation. Assembly graphs are a fundamental data structure used by genome and metagenome assemblers to represent sequences and their overlap info