Reposted by Tencho Tenev
RIPK1-driven #necroptosis in both tumor and stromal compartments found to be essential for effective immunogenic cell death-based therapy and immune checkpoint @meierlabicr.bsky.social doi.org/10.1038/s414...
Biologist, Senior Staff Scientist at @icrlondon.bsky.social #TNFR and #TLR signaling; #immunogenic cell death; #necroptosis; #innate immunity; #immunotherapy; #cancer