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Tencho Tenev

@ttenev.bsky.social
644 followers 728 following 5 posts

Biologist, Senior Staff Scientist at @icrlondon.bsky.social #TNFR and #TLR signaling; #immunogenic cell death; #necroptosis; #innate immunity; #immunotherapy; #cancer

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Reposted by Tencho Tenev
Nature Communications @natcomms.nature.com · 09/03/2026
RIPK1-driven #necroptosis in both tumor and stromal compartments found to be essential for effective immunogenic cell death-based therapy and immune checkpoint @meierlabicr.bsky.social doi.org/10.1038/s414...
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Tencho Tenev @ttenev.bsky.social · 24/06/2025
Great two day meeting organised by @icr.ac.uk . Lots of amazing talks and posters that culminated with keynote talk by Erik Sahai @eriksahailab.bsky.social . Well done to organisers.
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Reposted by Tencho Tenev
Waggoner Lab @labwaggoner.bsky.social · 09/04/2025
Tumor cells hijack the mRNA export pathway to obstruct nuclear export of retroelement transcripts for viral mimicry inhibition and immune evasion www.science.org/doi/10.1126/...
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Reposted by Tencho Tenev
Waggoner Lab @labwaggoner.bsky.social · 09/04/2025
Effective recognition of double-stranded RNA in human cells does not require activation of the antiviral interferon pathway www.science.org/doi/10.1126/...
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Reposted by Tencho Tenev
Rune Busk Damgaard @rbdamgaard.bsky.social · 21/01/2025
We made it to 100! 📢💯 The #ubiquitin and #ubl Starter Pack now includes 100 profiles to follow if you’re interested in any aspect of the field: signalling, structure and biochemistry, biology, mechanisms, proteostasis, TPD, chemical biology… Check out the list and let me know if you are missing.
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Connor G G Bamford @connorggbamford.bsky.social · 17/01/2025
Amazing role of non-pathogenic viruses in providing a benefit to host through suppression of cancer development www.cell.com/cancer-cell/...
cell.com
Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin
Sun-damaged normal skin contains many clonal mutations. Son et al. show that commensal papillomaviruses residing in keratinocytes help virus-specific CD8+ T cells detect and suppress the mutant clones...
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Reposted by Tencho Tenev
Prof. Akiko Iwasaki @virusesimmunity.bsky.social · 12/01/2025
Working with a great team to organize @keystonesymposia.bsky.social on "#LongCOVID and Other Post-Acute Infection Syndromes #PAIS" #KSLongCOVID26 @patientled.bsky.social @daltmann.bsky.social August 10-13, 2025 | Santa Fe Hope to see you there! keysym.us/KSLongCOVID26
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Tencho Tenev @ttenev.bsky.social · 10/01/2025
Weekend paper to read: doi.org/10.1186/s130...
doi.org
Divergent paths of mammary gland involution: unveiling the cellular dynamics in abruptly and gradually involuted mouse models - Breast Cancer Research
Background Epidemiological studies associate an increase in breast cancer risk, particularly triple-negative breast cancer (TNBC), with lack of breastfeeding. This is more prevalent in African America...
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Tencho Tenev @ttenev.bsky.social · 29/12/2024
What we eat? Royal Institution Christmas Lectures in three episodes starting soon. www.bbc.co.uk/programmes/m...
bbc.co.uk
BBC Four - Royal Institution Christmas Lectures, 2024: Chris van Tulleken - The Truth About Food, From Taste Buds to Toilet
Dr Chris van Tulleken explores the incredible journey food takes through our bodies.
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Reposted by Tencho Tenev
François Leulier @francoisleulier.bsky.social · 23/11/2024
After 11months on this platform, so happy to see the momentum finally happening! Let’s repeat a proper introduction: My lab studies how the #Microbiome together with #Nutrition influence #Development and Juvenile #Physiology using #Mice and #Drosophila as models… we also do lot’s of #Microbiology
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Stylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 20/11/2024
Are you ready for this? We are on Bluesky too!!! Follow the account of NATURE CELL BIOLOGY below! bsky.app/profile/natu...
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Nicole Campbell @drnicolecampbell.bsky.social · 20/11/2024
👋 fellow immunologists, it’s a pleasure to be with you all on bsky! I work on type I #interferons, I figured it would be neat to have a starter pack for those of us working on all things IFN! I’ll keep adding to it, let me know if you want to be included! #immunology #immunosky go.bsky.app/71vKZJA
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Pallett Lab UCL @pallettlab.bsky.social · 19/11/2024
We’ve jumped on board fully here on 🦋 A starter pack of those working on our favourite cell … the T cell 🥰🙈🥰 If you want an add let us know go.bsky.app/8B5P25c
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Ivano Amelio @ivanoamelio.bsky.social · 16/11/2024
Let's bring the #CellDeath community together here on 🦋 Just get in touch to join this Starter Pack go.bsky.app/R6mGrKU
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Reposted by Tencho Tenev
Bluesky @bsky.app · 16/11/2024
Another day, another million new people have joined Bluesky! 18M users? 🙂‍↔️ 18M friends 🙂‍↕️
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Tencho Tenev @ttenev.bsky.social · 15/11/2024
Good news for #Protacs www.nature.com/articles/d41...
nature.com
PROTAC protein degraders to drug the undruggable enter phase 3 trials
Pharmaceutical companies are investing in therapies that target proteins for degradation, with trials ongoing for cancer, autoimmune diseases and neurological disorders.
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