Sign in

Charlotte Capitanchik

@tinycaptain.bsky.social
1.4K followers 1.5K following 34 posts

RNA Bioinformatics Postdoc at Crick Institute/ UK DRI @ King's College London w/ Jernej Ule (@ulelab) and Ben Blencowe | Co-founder of Londonomics Network | Co-creator of Flow.Bio

PostsRepliesMedia
Reposted by Charlotte Capitanchik
Plant Science🍀🌱 @sciplant.bsky.social · 31/05/2026
Don’t reach for ChatGPT Images or Nano Banana as your first option when creating scientific images. There are multiple free and open-source images, icons, and tools for creating scientific illustrations. blog.stephenturner.us/p/free-open-... #plantscience @stephenturner.us @plant-sci.bsky.social
blog.stephenturner.us
Free and open-source images, icons, and tools for creating scientific illustrations
Phylopic, NIH Bioart, Bioicons, Scidraw, Open Science Art, Health Icons, Servier Medical Art, Biodiversity Heritage Library, the Noun Project, Segment Anything, Excalidraw, draw.io, Biographics
03821
Charlotte Capitanchik @tinycaptain.bsky.social · 26/02/2026
this looks useful! will have to try it out :)
000
Reposted by Charlotte Capitanchik
Liana Lareau @lianafaye.bsky.social · 25/02/2026
This is my love letter to mRNA: an Ignite talk I gave as a fundraiser for the Lawrence Hall of Science. Custom mRNA cancer vaccines could be a game changer, but anti-science policies make their future so uncertain. www.youtube.com/watch?v=WUlu...
youtube.com
Decoding mRNA: How AI & Vaccines Cure Cancer | Liana Lareau | Ignite Talk
YouTube video by Ignite Talks - Smart Ideas From Around the World
1135
Reposted by Charlotte Capitanchik
Journal of Cell Science @jcellsci.bsky.social · 17/02/2026
Read more about this research in our ‘First person’ interview with Reem Abouward: journals.biologists.com/jcs/article/...
Reem Abouward
052
Charlotte Capitanchik @tinycaptain.bsky.social · 11/12/2025
looks very useful!
010
Charlotte Capitanchik @tinycaptain.bsky.social · 05/12/2025
So great for bioinformatics training!
030
Charlotte Capitanchik @tinycaptain.bsky.social · 03/12/2025
come along to our first event of 2026 to chat about bioinformatics data engineering & meet like-minded folks ! @londonomics.bsky.social www.ticketsource.co.uk/whats-on/lon...
ticketsource.co.uk
040
Charlotte Capitanchik @tinycaptain.bsky.social · 27/11/2025
🫠
010
Reposted by Charlotte Capitanchik
Larry Hunter @proflhunter.bsky.social · 14/11/2025
Former OpenAI product safety leader sounding a loud warning about artificial intimacy. www.nytimes.com/2025/10/28/o...
nytimes.com
Opinion | I Led Product Safety at OpenAI. Don’t Trust Its Claims About ‘Erotica.’
061
Charlotte Capitanchik @tinycaptain.bsky.social · 07/11/2025
www.cnn.com/2025/11/06/u... absolutely sickening, such a painful read. LLMs could be powerful tools for science, but should never have been trained to interact with people like it is a friend. In a loneliness pandemic can you really expect people to resist this emotional junk food?
cnn.com
ChatGPT encouraged college graduate to commit suicide, family claims in lawsuit against OpenAI | CNN
A 23-year-old man killed himself in Texas after ChatGPT ‘goaded’ him to commit suicide, his family says in a lawsuit.
000
Reposted by Charlotte Capitanchik
Standplaats Kraków could really use some cash! @standplaatskrk.pl · 08/10/2025
an internet explorer window against the windows xp background with  a geocities.com address in the bar "/Kingofkings".

The page displayed is a broken image on a black background, and the sentence: "My name is Ozymandias, King of Kings; Look upon my Works, ye Mighty, and despair!"
2720181
Charlotte Capitanchik @tinycaptain.bsky.social · 01/10/2025
If I had to do a second PhD it would for sure be this one! So exciting!
010
Reposted by Charlotte Capitanchik
Ben Collins @bencollins.bsky.social · 22/09/2025
So cool they discovered the cause of autism on basically day they guessed they would. I’m also glad they are withholding this information for a few days to prep for a WrestleMania-style announcement. This is how science works.
319149912221
Charlotte Capitanchik @tinycaptain.bsky.social · 22/09/2025
Like & share our new promo vid for Flow.bio! Capturing just a little bit of that bioinformatics trauma 🫠 www.youtube.com/watch?v=MR-R...
flow.bio
Flow
010
Reposted by Charlotte Capitanchik
John Choiniere @johnchoiniere.bsky.social · 21/09/2025
Acetaminophen/paracetamol use in pregnancy doesn't cause autism, no matter what RFK says this week. This is not an unsettled question. Evidence summarized here: sciencebasedmedicine.org/tylenol-and-...
sciencebasedmedicine.org
Tylenol and Autism
Earlier this year, HHS secretary RFK Jr. predicted that, "By September, we will know what has caused the autism epidemic and we'll be able to eliminate those exposures." Scientists have been researc
261123430
Reposted by Charlotte Capitanchik
Oded Rechavi @odedrechavi.bsky.social · 19/09/2025
Only single cell sequencing of the all these post docs will reveal why
835447
Charlotte Capitanchik @tinycaptain.bsky.social · 02/09/2025
Congratulations to @bencekover.bsky.social for winning the best talk prize for schooling us all on best practises in mass scRNA-Seq data integration #Londonomics2025
030
Charlotte Capitanchik @tinycaptain.bsky.social · 02/09/2025
Can’t thank our career mentors enough for the great discussions in our mentorship session @margaridamcm.bsky.social @kristinaulicna.bsky.social @gavinpaulkelly.bsky.social and Mara Tatari 💪#Londonomics2025
010
Charlotte Capitanchik @tinycaptain.bsky.social · 02/09/2025
In the afternoon we had an excellent talk about AlphaMissense and AlphaGenome from @avsecz.bsky.social who generously allowed us to heckle him during the talk, answering all our questions!
000
Charlotte Capitanchik @tinycaptain.bsky.social · 02/09/2025
In the morning we enjoyed 11 short talks from computational biology ECRs - I especially liked @saniyakhullar.bsky.social’s talk on incorporating prior PPI knowledge into gene regulatory network inference #londonomics2025
010
Charlotte Capitanchik @tinycaptain.bsky.social · 02/09/2025
Had such a great time at #Londonomics2025 today - excellent talks and discussions - thank you to everyone who came along and shared their ideas with us.
031
Charlotte Capitanchik @tinycaptain.bsky.social · 01/09/2025
Sounds like a wonderful position
010
Charlotte Capitanchik @tinycaptain.bsky.social · 18/08/2025
RUN, DON'T WALK to sign up for the londonomics symposium! we gotta order the sandwiches soon, so grab your ticket while you can! come hear about AlphaGenome & other great omics work, get career advice and hang out with us, it'll be so great i promise register.oxfordabstracts.com/event/75604?...
register.oxfordabstracts.com
Oxford Abstracts Delegate Registration
000
Reposted by Charlotte Capitanchik
Will Ratcliff @wcratcliff.bsky.social · 12/08/2025
Not sure how many scientists here have tried Claude Code or similar command line coding assistants. I had a complicated family property tax problem that was best solved by a brute force Monte Carlo simulation approach, so I spent a few days coding up and analyzing a model with Claude Code.
19349128
Charlotte Capitanchik @tinycaptain.bsky.social · 07/08/2025
Did GPT-5 make this graph?
030
Charlotte Capitanchik @tinycaptain.bsky.social · 29/07/2025
Registration here ➡️ register.oxfordabstracts.com/event/75604?...
register.oxfordabstracts.com
Oxford Abstracts Delegate Registration
011
Charlotte Capitanchik @tinycaptain.bsky.social · 29/07/2025
Excited for this! Please do come and present your work :D
000
Reposted by Charlotte Capitanchik
Jay Brito Querido @jbquerido.bsky.social · 22/07/2025
This work is the result of a fantastic collaboration between my lab at the University of Michigan, Mitchell Guttman lab at Caltech, and Marko Jovanovic lab at Columbia University. www.cell.com/cell/fulltex... #Ribosomes #Science #CryoEM #RNA
cell.com
SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress
SPIDR, a massively multiplexed method that simultaneously maps dozens of RNA-binding proteins to their RNA targets at single-nucleotide resolution, uncovers new RNA-protein interactions and provides c...
0121
Charlotte Capitanchik @tinycaptain.bsky.social · 21/07/2025
😂
000
Reposted by Charlotte Capitanchik
UCSC Genome Browser @genomebrowser.bsky.social · 16/07/2025
New ENCODE4 long-read RNA-seq transcripts track for hg38 and mm10. Triplets (e.g. [1,1,3]) indicate start site, exon combination, and stop site for each transcript. Enrichment scores show how these change across tissue and cell line samples. Read more: genome.ucsc.edu/gold...
0267
Reposted by Charlotte Capitanchik
Onisillos @onisillos.bsky.social · 30/06/2025
"It is not just that LLM’s fail to induce proper world models of chess. It’s that they never induce proper worlds of anything. Everything that they do is through mimicry, rather than abstracted cognition across proper world models." garymarcus.substack.com/p/generative...
garymarcus.substack.com
Generative AI’s crippling and widespread failure to induce robust models of the world
LLM failures to reason, as documented in Apple’s Illusion of Thinking paper, are really only part of a much deeper problem
22012
Charlotte Capitanchik @tinycaptain.bsky.social · 23/06/2025
Totally agree!! "How to make the next PDB" This is exactly what we've attempted to do for functional genomics with flow.bio www.biorxiv.org/content/10.1...
010
Charlotte Capitanchik @tinycaptain.bsky.social · 13/06/2025
@simranolak.bsky.social 🙌
000
Charlotte Capitanchik @tinycaptain.bsky.social · 13/06/2025
incredible work by an incredible scientist (and friend)! very beautiful figures too www.cell.com/cell-systems...
cell.com
The molecular landscape of cellular metal ion biology
Aulakh et al. systematically investigated how metal ion availability impacts yeast biochemistry. Their metallomic, proteomic, and genetic screens reveal the widespread metal concentration dependence o...
152
Reposted by Charlotte Capitanchik
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 13/05/2025
"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants. Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
311286940
Charlotte Capitanchik @tinycaptain.bsky.social · 09/05/2025
can't wait to try this out :D
010
Reposted by Charlotte Capitanchik
Nicky Whiffin @nickywhiffin.bsky.social · 11/04/2025
🚨I could not be more excited to share our new preprint on saturation genome editing of the small nuclear RNA (snRNA) RNU4-2: www.medrxiv.org/content/10.1... A super fun collaboration with incredible duo @gregfindlay.bsky.social @joachimdejonghe.bsky.social from @crick.ac.uk 🧬🖥️🩺 🧵1/12
medrxiv.org
Saturation genome editing of RNU4-2 reveals distinct dominant and recessive neurodevelopmental disorders
Recently, de novo variants in an 18 nucleotide region in the centre of RNU4-2 were shown to cause ReNU syndrome, a syndromic neurodevelopmental disorder (NDD) that is predicted to affect tens of thous...
410049
Reposted by Charlotte Capitanchik
Oscar Wilkins @oscargwilkins.bsky.social · 08/01/2025
We're so pleased that groups have been ordering our TDP-REG vectors from Addgene! Please be aware that splicing minigenes cannot easily be used with lentiviruses, because the lentiviral RNA can get spliced before viral packaging! Better to use piggybac or similar, AAV, or just transient transfection
052
Reposted by Charlotte Capitanchik
Alex Harston @harston.io · 14/12/2024
We are so close to AGI
031
Reposted by Charlotte Capitanchik
Austin Wang @austintwang.bsky.social · 11/12/2024
(1/10) Excited to announce our latest work! @arpita-s.bsky.social, @amanpatel100.bsky.social , and I will be presenting DART-Eval, a rigorous suite of evals for DNA Language Models on transcriptional regulatory DNA at #NeurIPS2024. Check it out! arxiv.org/abs/2412.05430
arxiv.org
DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA
Recent advances in self-supervised models for natural language, vision, and protein sequences have inspired the development of large genomic DNA language models (DNALMs). These models aim to learn gen...
17027
Reposted by Charlotte Capitanchik
Frances Yap @ribo1214.bsky.social · 07/12/2024
ribosomal A-site m6A induces mRNA degradation 🧪 #RNASky www.cell.com/molecular-ce...
cell.com
m6A sites in the coding region trigger translation-dependent mRNA decay
Zhou et al. discovered a specific role of adenosine modifications in the coding region of mRNAs. These chemical alterations slow down the movement of the ribosome during translation and trigger degradation of the corresponding mRNAs.
04721
Reposted by Charlotte Capitanchik
Kieran Campbell @kieranrcampbell.bsky.social · 05/12/2024
A related issue is some data (cells) appearing multiple times under different datasets or collections. Sometimes it’s obvious and sometimes it’s not, but the consequence is it’s really hard to do a clean train/test split
141
Reposted by Charlotte Capitanchik
Tomàs Montserrat Ayuso @tmontsay.bsky.social · 03/12/2024
Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨 We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research! Read more: bmcgenomics.biomedcentral.com/articles/10.... 1/8
bmcgenomics.biomedcentral.com
High content of nuclei-free low-quality cells in reference single-cell atlases: a call for more stringent quality control using nuclear fraction - BMC Genomics
The advent of droplet-based single-cell RNA-sequencing (scRNA-seq) has dramatically increased data throughput, enabling the release of a diverse array of tissue cell atlases to the public. However, we...
4244126
Charlotte Capitanchik @tinycaptain.bsky.social · 02/12/2024
I wonder if the participants are aware of the barriers to accessing their generously donated data
011
Charlotte Capitanchik @tinycaptain.bsky.social · 21/11/2024
Hell yeah!!
010
Reposted by Charlotte Capitanchik
Natania Barron ~ Fantasy Author @natania.bsky.social · 14/05/2023
Here is a selection of medieval hedgehogs, as portrayed in illuminated manuscripts. Mostly from the 14th and 15th centuries. Why? Because they are cute and I love them. And you all seem like discerning people of good taste.
1342982
Reposted by Charlotte Capitanchik
Shannon Hale @shannonhale.bsky.social · 18/11/2024
“I'm writing a first draft and reminding myself that I'm simply shoveling sand into a box so that later I can build castles.” This was probably my most viral tweet. I've seen it pop up in a lot of quote aggregators, sometimes attributed to a wonderful but definitely not-me filmmaker.
14910614740
Reposted by Charlotte Capitanchik
Julien Richard Albert @jrichardalbert.bsky.social · 17/11/2024
The vast majority of my "AHA!" moments are from surfing around the UCSC genome browser. Thanks, @ucscgenomics.bsky.social ! This little screenshot made my week
3195
Reposted by Charlotte Capitanchik
Sebastian S. Cocioba @atinygreencell.bsky.social · 11/11/2024
Very rare opportunity! Get em before they sell out until next year. Please consult your doctor before engaging in Physiological Relevance. Side effects may include sense of purpose, cessation of existential dread, mild nausea, and a dislike of peas. Ask your local Oded if PR is right for you.
0212
Charlotte Capitanchik @tinycaptain.bsky.social · 11/11/2024
is it a damning indictment of my brain that i immediately recognised this formatting to be most akin to yu-gi-oh cards
120