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Luca Livraghi

@lucalivraghi.bsky.social
502 followers 624 following 24 posts

Butterfly wing Evo Devo. Postdoc at George Washington University

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Reposted by Luca Livraghi
Antoine Molaro @antoinemolaro.bsky.social · 08/10/2026
Hello World ! Its pre-print time ! Awesome collaboration led by Michel Cohen-Tannoudji (not on Bsky) and the one and only @deborahbourchis.bsky.social. #BFF We solved the molecular mechanism underlying a mysterious hybrid incompatibility in mice: the DDK syndrome. 🧵🍿 www.biorxiv.org/content/10.6...
biorxiv.org
Transposable Element insertions Repurpose Immune Endonucleases as Drivers of Reproductive Isolation in Mice
The emergence of reproductive barriers between closely related populations is a fundamental step in speciation, yet the underlying genetic mechanisms remain poorly understood in mammals. Here we resol...
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Joe Hanly @hanliconius.bsky.social · 09/10/2026
We're really entering a new era of lepidopteran developmental biology, and two great new papers highlight this. First, Ximena Ramos, Katie Reding and Leslie Pick investigate segmentation in V. cardui with RNAi, @dev-journal.bsky.social journals.biologists.com/dev/article/...
journals.biologists.com
Segmentation gene expression and function in Vanessa cardui, an emerging model for Lepidoptera
Highlighted Article: Mechanisms controlling embryonic development are underexplored in Lepidoptera. Here we show that only some of the known segmentation genes contribute to body patterning in the mod...
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S. Wren Sorkhabi @ssorkhabi.bsky.social · 30/09/2026
Excited to be able to share the first chapter of my master’s thesis which was an absolute blast to think about and write with my amazing co-authors :)
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Dr George RA Hancock 🦋🦎 @grahancock.bsky.social · 30/09/2026
Woohoo, it's now live! We show, using four lines of evidence, that butterfly wings can create illusory motion effects! @esbriolat.bsky.social, @scienceanna.bsky.social, @lauraakelley.bsky.social, @jtroscianko.bsky.social www.nature.com/articles/s41...
nature.com
Butterfly wing patterns in flight create powerful illusory motion cues - Nature
Butterfly wing patterns and flight dynamics work in tandem to create powerful visual illusions that confuse predators, potentially representing one of the most successful visual defence strategies in ...
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Joe Hanly @hanliconius.bsky.social · 28/09/2026
I added some features to what is now called Genome Observatory. By request, you can now organise by taxon. Here we’re looking at the very well-sequenced order Lepidoptera 1/
A view of genome counts of Lepidoptera over time.
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Joe Hanly @hanliconius.bsky.social · 22/09/2026
I hate to do this with real data, but this is a persistent data vis issue in chromosome synteny riparian plots that we Need to get better at. Left, a synteny plot published today. Right, a rearranged version with exactly the same gross arrangement but with reordered chromosomes:
chromosome synteny riparian plot in which every chromosome has crossing lineschromosome synteny plot in which no chromosomes have crossing lines. The underlying structure is identical.
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Richard Merrill @dickmerrill.bsky.social · 10/09/2026
Very excited to see this multi-faceted* study, led by Shane Wright and representing years of work on visual evolution and perception in Heliconius as part of our ERC Starting Grant, released into the world! 🦋*pun very much intended www.biorxiv.org/content/10.6...
biorxiv.org
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Rebekah Rogers @evolscientist.bsky.social · 19/08/2026
We will be hosting DC Area research talks on Evolutionary Genetics at GW starting this Fall. First Tuesday of the Month at 3pm, Science and Engineering Hall. Co-founded with Manus Patten at Georgetown University. Please help spread the word.
The Inaugural Meeting of DC Evolutionary Genetics
Tuesday Sept 1st, 3pm-4pm 
The George Washington University
SEH 8750 

 
Rapid Divergence across Short Geographic Distances in Fireflies
Rebekah Rogers
The George Washington University

& 

How organisms cope with selfish genetic elements 
 Manus Patten 
Georgetown University
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Rebekah Rogers @evolscientist.bsky.social · 13/08/2026
Our new work on Elephant Genomes, led by Jeroen Kappelhof!!
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Marco Grillo @mgrillo.bsky.social · 19/08/2026
Latest from our lab: highly multiplexed spatial miRNA profiling, with @agustinrobles.bsky.social, @augjensen.bsky.social, @nilssonlab.org and others! www.biorxiv.org/content/10.6...
biorxiv.org
Spatial microRNA profiling at single-cell resolution by in situ barcoded extension
The spatial organization of post-transcriptional regulation is a fundamental yet difficult to access layer of tissue biology. MicroRNAs (miRNAs) are small RNAs with a key role in post-transcriptional ...
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Thea Kongsted @theakongsted.bsky.social · 11/05/2026
Although the red pigments made by flowering plants and liverworts are produced by distinct chemical pathways, here we found that they are induced by homologous complexes of transcription factors. @currentbiology.bsky.social
cell.com
Replicated repurposing of an ancestral transcriptional complex in land plants
Kongsted et al. find that, while the red pigments produced in liverworts and seed plants are distinct, they are regulated by homologous MYB-bHLH transcriptional complexes. They also find that in liver...
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Isabel Almudi @isabelalmudi.bsky.social · 07/08/2026
What happens when evolution adds an extra pair of eyes? Male mayflies evolve an extra pair of dorsal compound eyes, the Turbanate eyes, thought to help males detect females during mating swarms. we have investigate how this remarkable evolutionary novelty develops. www.biorxiv.org/content/10.6...
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Rebekah Rogers @evolscientist.bsky.social · 04/08/2026
Officially recruiting postdocs at GW. If you are interested in genetic novelty, structural variation, or evo genetics please get in touch! We have data sets on mulitple organisms with large population sizes (Drosophila, Megalonaias nervosa) and species in decline (fireflies, mussels, elephants).
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Joséphine Ledamoisel, PhD @joledamoisel.bsky.social · 15/07/2026
Our new paper is officially out ! 🎉 We found that iridescence tends to converge between sympatric Morpho butterflies! This signal is likely driven by predation pressures, bringing new evidence to the evasive mimicry hypothesis, i.e. the evolution of confusion patterns in hard-to-catch prey!
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Emília Santos @emiliapsantos.bsky.social · 14/07/2026
🎨 job alert 🐠 Come join us! We have two positions open! These are part of our @erc.europa.eu funded project on the mechanisms underpinning convergence of colour patterns in cichlid fishes! Closing date: 16th August. Postdoc: www.cam.ac.uk/jobs/researc... Technician: www.cam.ac.uk/jobs/researc...
static.klipy.com
Callipterus Cichlid Collecting Shell
ALT: Callipterus Cichlid Collecting Shell
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 12/07/2026
Just added a couple more job apps (thanks Rachel and Arun!) but if you've gotten a job in industry, academia (R1, PUI, whatever!) in the last 5 years or so, please consider submitting your job app materials to help other folks! github.com/RILAB/statem...
github.com
GitHub - RILAB/statements: Successful Job Applications and Grants
Successful Job Applications and Grants. Contribute to RILAB/statements development by creating an account on GitHub.
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Matt Benton @matthewabenton.bsky.social · 08/07/2026
Differences b/w key developmental events in different species are common. We wanted to QUANTITATIVELY describe such differences, + discover the CAUSES and CONSEQUENCES of the differences Read the full thread for more, including how we achieved the goal of many dev bio folk: we SPED UP DEVELOPMENT!!
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Andrew Carroll @acarroll.bsky.social · 01/07/2026
How good is MiniBWA, the successor to BWA? To test it, I ran MiniBWA on sequencing from 76 different species, comparing mapping speed, rate and accuracy with BWA MEM. In short, it's really good. If you map short reads, it's well worth your time. andrewcarroll.github.io/2026/06/30/t...
andrewcarroll.github.io
The Best of Both Worlds - Assessing MiniBWA
Recently, Heng Li released MiniBWA (GitHub) alongside a paper by Heng Li and Nils Homer describing the method (paper). MiniBWA builds on the approaches in Minimap2 (also by Heng Li), but falls back on...
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Rebekah Rogers @evolscientist.bsky.social · 18/06/2026
Big news this week from The Rogers Lab. We will be moving to GW University in Washington DC, starting August 1st. We will be hiring postdocs and recruiting new students! Email me if interested or come find me at SMBE!
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Camille Cornet @camillecornet.bsky.social · 18/06/2026
🧬🦋 New preprint out! 🦋🧬 What mechanisms underlie large-scale chromosomal rearrangements? Why do rearrangement rates vary so massively across taxa? We explored these questions in Erebia butterflies, a genus with extraordinary chromosome number diversity, from 7 to 52! www.biorxiv.org/content/10.6...
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Jessica Foley @jessicafoley14.bsky.social · 16/06/2026
Very excited to finally have this out in the world! The first paper from my PhD (and my first first-author publication) makes the case for a new entrant to the world of long-lived animal models: Heliconius butterflies. Out now in @natcomms.nature.com www.nature.com/articles/s41... (1/10)
nature.com
Evolution of increased longevity and slowed ageing in a genus of tropical butterfly - Nature Communications
Studying long-lived species across the animal kingdom could provide insights into healthy ageing in humans. This study reveals long lifespans and slowed ageing in Heliconius butterflies, identifying t...
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Daniel Gorelick @danielgorelick.bsky.social · 03/06/2026
Paying peer reviewers works. Expanded Fast & Fair experiment @biologyopen.bsky.social: • 5.5 vs 37.7 working days to decision with reviews • ~3 vs ~9 reviewer invitations per manuscript • no reduction in editor-assessed review quality • similar acceptance rates www.biorxiv.org/content/10.6...
Scatter plot showing that Fast & Fair peer review reached first decision with reviews much faster than conventional peer review: mean 5.5 versus 37.7 working days. Most Fast & Fair manuscripts met the 7-working-day target, while conventional manuscripts were slower and more variable, up to 116 working days.
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Matthew Hahn @3rdreviewer.bsky.social · 02/06/2026
Very happy to announce a big new paper from the lab, led by grad students @smishra677.bsky.social and Laia Pomar-Pallarès (in collaboration with @roblanfear.bsky.social). We introduce a new way to study introgression, with accompanying software (DAFT) 1/n 🧵 www.biorxiv.org/content/10.6...
biorxiv.org
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Science Magazine @science.org · 28/05/2026
Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. scim.ag/4nTQ3nq
How animals sense Earth’s magnetic field is one of biology’s enduring mysteries. Researchers have now identified superparamagnetic macrophages in the livers of rock pigeons (Columba livia) to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation.

Photo: Andreas Teichmann/laif/Redux
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Rob Patro @robp.bsky.social · 27/03/2026
The people who believe that generative AI development & adoption everywhere is the ultimate goal & the first order predictor of success are insufferable. So are the people who think that AI can't ever produce anything useful and that everything they do produce is "slop". I miss reasoned arguments.
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Arnaud Martin @evolvwing.bsky.social · 17/05/2026
introducing barfbow, a little tool that aims to encourage the use of variable brightness to improve effective com, accessibility and scientific accuracy in figures. github.com/evolvwing/ba... If you need palettes with colors that are easy to distinguish on a plot or map, pls check it out!
visual output from barfbow, a Python tool to generate OKLCh color palettes with varying brightness, including an example of generated palett, plus color-vision simulations, monochrome rendering, named swatches, and OKLCh walk wheels.
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Joe Hanly @hanliconius.bsky.social · 01/05/2026
Can anyone point me towards companies that are actively trying to reduce DNA library prep cost? Like, is there a business out there trying for sub-$1 libraries yet?
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Digital Naturalism Laboratories @dinalab.bsky.social · 15/05/2026
Hey look we got a cool new paper out in @methodsinecoevol.bsky.social all about the MOTHBOX! Hubert put together a really nice paper with our team including Bernat Fortet, Daisy H. Dent, @wellreadpanda.bsky.social and @briannaljohns.bsky.social besjournals.onlinelibrary.wiley.com/doi/epdf/10....
besjournals.onlinelibrary.wiley.com
Mothbox and Mothbot: Automated light trap and data processing system for scalable insect monitoring
Insects represent the most diverse group of organisms on Earth and comprise the majority of known species; yet they are seldom accounted for in large-scale biodiversity monitoring systems and cons...
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Chris Jiggins @chrisjiggins.bsky.social · 15/05/2026
Excited to see this out!
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Stephen Montgomery @ebablab.bsky.social · 11/05/2026
🚨Job claxon🚨 4-year #Postdoc available in our lab in @camzoology.bsky.social developing molecular and anatomical approaches to mapping evolutionary changes in the brain, using #Heliconiini butterflies. Come join us, we are nice. 🧪 www.cam.ac.uk/jobs/researc...
An immunostaining section through a Heliconius brain. Staining and imaging by Dr Max Farnworth.
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Alejandro Berrio Escobar @urchinpapi.bsky.social · 16/04/2026
It takes two to tango but gastrulation is a contra dance Cells move through changing partners and signals, and many Wnts act together to keep the choreography coordinated in space and time. That’s the core idea behind our new paper on gut formation in #seaurchins 🧵
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Joe Hanly @hanliconius.bsky.social · 16/03/2026
I've just had a jaw-to-the-floor moment with this new paper from the Hines lab. They describe a yellow-white switch in bees, which maps to the same TF as the yellow-white switch in Colias butterflies, previously described by the @chriswheat.bsky.social lab. journals.plos.org/plosgenetics...
A map of anatolia, indicating the spatial distribution of yellow and white bees. Figure 1 from https://www.nature.com/articles/s41467-019-13596-2
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MwahahahahahadScientist @mads100tist.bsky.social · 10/03/2026
What do you mean I have to publish another paper after I am done with this one. That doesn't sound right. That sounds like a pyramid scheme
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Vincent Debat @vincentdebat.bsky.social · 07/03/2026
Species-specific spectral tuning of motion vision in butterflies: Current Biology www.cell.com/current-biol...
cell.com
Species-specific spectral tuning of motion vision in butterflies
Supple et al. investigate the spectral sensitivity of motion-sensitive descending neurons (DNs) connecting the brain to thoracic motor centers in butterflies. Optic flow-sensitive DNs are spectrally b...
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Anyi Mazo-Vargas @anyimv.bsky.social · 27/02/2026
🦋✂️🧬 🧪 New preprint! Led by @donyaniyaz.bsky.social CRISPR‑Cas9 knockouts of ABCG transporters across butterflies & moths reveal how pigment pathways shape color during development. #CRISPR #Lepidoptera #pigmentation Feedback welcome 👩‍🔬 www.biorxiv.org/content/10.6...
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Joe Hanly @hanliconius.bsky.social · 27/02/2026
New preprint form me and the McMillan lab at STRI and Martin lab at GWU, digging into scale cell type specification and differentiation in Heliconius wings, with some insights on the lncRNA gene ivory. www.biorxiv.org/content/10.6... Comments/suggestions welcome!
Heliconius erato demophoon sat on a pink, yellow and white lantana flower. The left side of the butterfly is white, while the right side is the usual black and red, but with some white clonal patches.
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Shen Tian 田申 @tianshenbio.bsky.social · 27/02/2026
Amazing peppered moth story from Saccheri lab - same locus, but different structural variants, underly parallel evolution of industrial melanism in the UK and across continental Europe.
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Wei Shen 沈 伟 @shenwei356.bsky.social · 27/02/2026
Can't wait to release a 10-year-old birthday version for SeqKit! - 10 years - 2 papers, 3500 citations - 20 contributors - 40 subcommands - 880 commits - 500 issues - 685.5K Bioconda total downloads Thank you all, dear contributors and users! I'll keep maintaining it. github.com/shenwei356/s...
github.com
Release SeqKit v2.13.0 (10-year-old birthday version) · shenwei356/seqkit
Changelog SeqKit is 10 years old! SeqKit v2.13.0 - 2026-02-28 seqkit: add support for reading and writing LZ4 compression format. new command: seqkit sample2: improved seqkit sample by @stahiga....
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Judith Mank @judithmank.bsky.social · 25/02/2026
Something I’ve learned - the best research environments aren't sterile. They're alive with creativity and warmth, with huge fish murals and dogs who have no idea what a p-value is but show up to lab meeting anyway. Science is a human endeavour and humans need to be inspired by their surroundings.
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Arnaud Martin @evolvwing.bsky.social · 25/02/2026
Super excited about these results and new system. Mapping, Expression, Loss-of-Function I'm floored by how this locus seem to integrate all the spatial info to sketch the minute details of the phenotype, and how this is prone to evol tweaks Large hyperdiverged haplotype without an inversion.
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Luca Livraghi @lucalivraghi.bsky.social · 25/02/2026
New pre-print with some updates on ivory:miR193 in a highly polymorphic moth. www.biorxiv.org/content/10.6... We mapped ivory (again!?) this time controlling aspects of camouflage in Anticarsia gemmatalis. Mapping, SVs, Expression and Function. Comments/suggestions welcome!
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Luca Livraghi @lucalivraghi.bsky.social · 12/02/2026
Me when trying to submit sequences to SRA
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Gabriela Montejo-Kovacevich @gmkov.bsky.social · 27/12/2025
We’ve been working on this paper longer than it took adaptive alleles to cross the species barrier (in both directions) and make two pests ever more resistant to the things we throw at them. New preprint out 🧬🌱🐛
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Life Science Studios - Scientific Illustration @lifesciencestudios.bsky.social · 16/12/2025
Here are just a few of the many fish I painted this year (not to scale). It's fun to stick a bunch of them together into a collage and see some of the incredible diversity of body shape and color patterns. Merry Fishmas! 🐡🐟🐠
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Aaron Quinlan (he/him) @aaronquinlan.bsky.social · 02/12/2025
We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n
quinlanlab.org
Intro to Bedder – The Quinlan Lab
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Stephen Montgomery @ebablab.bsky.social · 21/11/2025
🚨RA/PhD position available in evolutionary neurobiology 🚨 Working on a deep dive into circuit changes during mushroom body expansion in Heliconius butterflies @camzoology.bsky.social - employment benefits - 4 years funding - 1000% fun Deadline: 14/1/2026 Details: www.cam.ac.uk/jobs/researc...
Shades of blue and red in a slice through an immuno stained brain showing some deliciously lovely looking mushroom body lobes - ripe for investigation during a funded PhD - and the central complex. Image credit: Dr Max Farnworth
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Arnaud Martin @evolvwing.bsky.social · 16/11/2025
🚨New paper! 🚨 @jasminealqassar.bsky.social led this work on the silk glands of the pantry moth. These two long tubes inside the caterpillar continuously make a ton of silk How does this special organ work? www.cell.com/iscience/ful... @cp-iscience.bsky.social 🧵THREAD🧵
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Luca Livraghi @lucalivraghi.bsky.social · 12/11/2025
Beautiful work, as always
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Luca Livraghi @lucalivraghi.bsky.social · 12/11/2025
Hey Lep researchers! "Given the risks of transgene remobilization and instability associated with piggyBac transposases of lepidopteran origin, we urge researchers interested in developing transgenesis in moths or butterflies to consider using Minos-based tools."
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Mark A. Hanson @hansonmark.bsky.social · 11/11/2025
We wrote the Strain on scientific publishing to highlight the problems of time & trust. With a fantastic group of co-authors, we present The Drain of Scientific Publishing: a 🧵 1/n Drain: arxiv.org/abs/2511.04820 Strain: direct.mit.edu/qss/article/... Oligopoly: direct.mit.edu/qss/article/...
A table showing profit margins of major publishers. A snippet of text related to this table is below.

1. The four-fold drain
1.1 Money
Currently, academic publishing is dominated by profit-oriented, multinational companies for
whom scientific knowledge is a commodity to be sold back to the academic community who
created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis,
which collectively generated over US$7.1 billion in revenue from journal publishing in 2024
alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit
margins have always been over 30% in the last five years, and for the largest publisher
(Elsevier) always over 37%.
Against many comparators, across many sectors, scientific publishing is one of the most
consistently profitable industries (Table S1). These financial arrangements make a substantial
difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor &
Francis revenues were generated in North America, meaning that North American
researchers were charged over US$2.27 billion by just two for-profit publishers. The
Canadian research councils and the US National Science Foundation were allocated US$9.3
billion in that year.A figure detailing the drain on researcher time.

1. The four-fold drain

1.2 Time
The number of papers published each year is growing faster than the scientific workforce,
with the number of papers per researcher almost doubling between 1996 and 2022 (Figure
1A). This reflects the fact that publishers’ commercial desire to publish (sell) more material
has aligned well with the competitive prestige culture in which publications help secure jobs,
grants, promotions, and awards. To the extent that this growth is driven by a pressure for
profit, rather than scholarly imperatives, it distorts the way researchers spend their time.
The publishing system depends on unpaid reviewer labour, estimated to be over 130 million
unpaid hours annually in 2020 alone (9). Researchers have complained about the demands of
peer-review for decades, but the scale of the problem is now worse, with editors reporting
widespread difficulties recruiting reviewers. The growth in publications involves not only the
authors’ time, but that of academic editors and reviewers who are dealing with so many
review demands.
Even more seriously, the imperative to produce ever more articles reshapes the nature of
scientific inquiry. Evidence across multiple fields shows that more papers result in
‘ossification’, not new ideas (10). It may seem paradoxical that more papers can slow
progress until one considers how it affects researchers’ time. While rewards remain tied to
volume, prestige, and impact of publications, researchers will be nudged away from riskier,
local, interdisciplinary, and long-term work. The result is a treadmill of constant activity with
limited progress whereas core scholarly practices – such as reading, reflecting and engaging
with others’ contributions – is de-prioritized. What looks like productivity often masks
intellectual exhaustion built on a demoralizing, narrowing scientific vision.A table of profit margins across industries. The section of text related to this table is below:

1. The four-fold drain
1.1 Money
Currently, academic publishing is dominated by profit-oriented, multinational companies for
whom scientific knowledge is a commodity to be sold back to the academic community who
created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis,
which collectively generated over US$7.1 billion in revenue from journal publishing in 2024
alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit
margins have always been over 30% in the last five years, and for the largest publisher
(Elsevier) always over 37%.
Against many comparators, across many sectors, scientific publishing is one of the most
consistently profitable industries (Table S1). These financial arrangements make a substantial
difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor &
Francis revenues were generated in North America, meaning that North American
researchers were charged over US$2.27 billion by just two for-profit publishers. The
Canadian research councils and the US National Science Foundation were allocated US$9.3
billion in that year.The costs of inaction are plain: wasted public funds, lost researcher time, compromised
scientific integrity and eroded public trust. Today, the system rewards commercial publishers
first, and science second. Without bold action from the funders we risk continuing to pour
resources into a system that prioritizes profit over the advancement of scientific knowledge.
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