Reposted by Mike LeeJeremy Berg @jeremymberg.bsky.social · 24/07/2026My quote of the day The light obtained by setting straw men on fire is not what we mean by illumination. Adam Gopnik 05711
Reposted by Mike LeeCosimo Commisso @cosimocommisso.bsky.social · 28/05/2026Still time to send an abstract and register for the FASEB Cell Signaling in Cancer meeting. There are many speaking slots available for proffered abstracts, along with a fantastic lineup of speakers. Join us in Kentucky! events.faseb.org/event/Cell-S... 053
Mike Lee @theleelab.bsky.social · 19/05/2026The 2026 FASEB Meeting on Cell Signaling in Cancer will be held in Louisville, KY July 13-15. It's not too late to join us! The abstract submission deadline is June 1. To view the speaker lineup, submit your abstract, and register, check out our conference website: events.faseb.org/event/Cell-S... 010
Reposted by Mike LeeDenis Wirtz @deniswirtz.bsky.social · 27/02/2026NIH is not issuing awards. You may think that it's because they it is coming up with new directions of research...The apposite is true. Here is a graph showing how many fewer new funding opportunities that NIH has posted over time. -91%, a trend that started on Jan 2025. 42622
Mike Lee @theleelab.bsky.social · 19/11/2025Life Science Editors wrote a really great "Snippet" about our recent paper describing PDAR. @lifescienceeditors.bsky.social @cp-cell.bsky.social Why cells die without Pol II www.lifescienceeditors.com/2025/11/15/w...lifescienceeditors.comWhy cells die without Pol II - Scientific editing and writing experts - Life Science EditorsScientific editing and writing experts for manuscripts and grants 170
Reposted by Mike LeeCarl T. Bergstrom @carlbergstrom.com · 24/10/2025The dark truth behind FormatMyPaper.comubadah.substack.comBeware giving this site your unpublished dataUsers noticed the website had fake testimonials and a domain name registered seemingly overnight. 818579
Reposted by Mike LeeStand Up for Science! @standupforscience.net · 09/10/2025RFK Jr. has a less-than-zero understanding of how science works. "Make the proof" should be disturbing for anybody who cares about health, truth, or democracy. Join our fight to impeach RFK Jr. here 👉 www.standupforscience.net/quack-o-gram... #impeachrfk #impeachthequackstandupforscience.net 817657
Reposted by Mike LeeMeidasTouch @meidastouch.com · 26/09/2025🚨 BREAKING: James Comey posts a video statement following his indictment "My family and I have known for years that there are costs to standing up to Donald Trump...But I'm not afraid. And I hope you're not either...And I'm innocent. So let's have a trial and keep the faith." 523117651901
Reposted by Mike LeeNature @nature.com · 25/09/2025We used machine-learning tools in an attempt to recreate the method for cutting funding, and then applied it to past US NIH grants to reveal the broad-reaching consequences go.nature.com/4pBArFHgo.nature.comWhat research might be lost after the NIH’s cuts? Nature trained a bot to find outWe used machine-learning tools in an attempt to recreate the method for cutting funding, and then applied it to past US National Institutes of Health grants to reveal the broad-reaching consequences of such action. 15132
Reposted by Mike LeeMax Kozlov @maxkozlov.bsky.social · 25/09/2025NEW: Nature trained AI to predict which NIH grants from 2014 would have been cut if the Trump admin had its way back then — and what science would have been lost to history. "The results show the damage that cuts in funding can do to research, and the unpredictable nature of the research process." 212459
Mike Lee @theleelab.bsky.social · 22/08/2025A nice Q&A with Nick Harper about the discovery of PDAR, and his road to becoming a scientist @umasschan.bsky.social www.umassmed.edu/dsb/dsb-comm... 040
Mike Lee @theleelab.bsky.social · 15/08/2025I’m excited to highlight our latest paper, just published in Cell 🎉 We report the existence of a previously uncharacterized signaling pathway that is responsible for activating cell death upon loss of gene expression. 1/n 🧪 www.cell.com/cell/fulltex...cell.comRNA Pol II inhibition activates cell death independently from the loss of transcriptionWhen RNA polymerase II (RNA Pol II) is inhibited, the inhibition is sensed and signaled to mitochondria, leading to programmed cell death independently of the loss of RNA Pol II transcription activity... 35623
Reposted by Mike LeeAbby Dernburg @adernburg.bsky.social · 31/07/2025For who still thinks this can’t happen here… it’s already happening. www.theatlantic.com/science/arch...theatlantic.comEvery Scientific Empire Comes to an EndAmerica’s run as the premiere techno-superpower may be over. 25935
Reposted by Mike LeeJoshua Weitz @joshuasweitz.bsky.social · 25/06/2025"[A] sleeper issue is the proposed 40 percent cut to the National Institutes of Health, in the White House’s proposed budget for the next fiscal year." Perhaps injecting some economic impact data may help awaken what should not be a sleeper issue... @prospect.org scienceimpacts.org/fy26 13113
Mike Lee @theleelab.bsky.social · 23/06/2025Things have been challenging over these last few months, but we also had a lot to celebrate... Tiana and Mika joining the lab 🎉, Kelly passing her QE 🎉, Gavin publishing a paper and submitting another 🎉, Megan publishing a paper 🎉, Nick getting excellent reviews 🎉 ...so we did a paint nite. 050
Reposted by Mike LeeMichael E. Mann @michaelemann.bsky.social · 29/05/2025Trump’s new ‘gold standard’ rule will destroy American science as we know it" by Colette Delawalla (@cdelawalla.bsky.social), Victor Ambros, Carl Bergstrom, Carol Greider, Michael Mann and Brian Nosek for @theguardian.com: www.theguardian.com/commentisfre...theguardian.comTrump’s new ‘gold standard’ rule will destroy American science as we know it | Colette DelawallaThe new executive order allows political appointees to undermine research they oppose, paving the way to state-controlled science 12369223
Reposted by Mike LeeVijay G. Sankaran @bloodgenes.bsky.social · 20/05/2025www.forbes.com/sites/johndr...forbes.comTrump’s NIH And NSF Cuts Estimated To Cost The U.S. Economy $10 Billion AnnuallyEconomists find public R&D drives U.S. productivity growth — and pays for itself 044
Reposted by Mike LeeNeil deGrasse Tyson @neildegrassetyson.com · 20/05/2025Not that anyone asked, but during my tenure on the Pentagon’s Defense Innovation Board, under part of Obama-2 and all of Trump-1, we visited Military Bases domestically & abroad. At no time did any member of the Armed Forces I met say to me: “America needs less science funding.” 331306180
Reposted by Mike LeeBen Allen @evodynamics.bsky.social · 15/05/2025Grants on antibiotic resistance (and many other things) cancelled "due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." Every single Jewish org needs to stand up and speak clearly against this weaponization of antisemitism 12510
Reposted by Mike LeeHealth Nerd @gidmk.bsky.social · 15/05/2025"People should not take medical advice from me" ~ the man directly in charge of medical advice for the United States 37512
Reposted by Mike Leeboehninglab @boehninglab.com · 09/05/2025www.thenation.com/article/poli...thenation.comInside the Bloodbath at the NIHSources say that a climate of fear has spread throughout the agency as the Trump administration takes a hatchet to its core functions. 033
Reposted by Mike LeeDon Moynihan @donmoyn.bsky.social · 19/04/2025Set aside the headline, this is a good primer on the how the federal govt wanted higher Ed to take on a bigger research role, and funded the infrastructure to make that possible via merit-based peer reviewed processes. The research funding is not entitlements and cutting it comes w real costs 12323108
Reposted by Mike LeeTalia Hatkevich @taliahatkevichphd.bsky.social · 19/04/2025Yyyyyyeeeeessssssa!!!! We are finally standing up!!!!!!!!!!!! 0203
Reposted by Mike LeeCarolyn Bertozzi @carolynbertozzi.bskyverified.social · 14/04/2025Harvard steps up www.harvard.edu/research-fun...harvard.edu 015623
Reposted by Mike LeeAdam Serwer @adamserwer.bsky.social · 14/04/2025What we saw today was two jumped up thugs and their bootlicking sychophants laughing at the US Constitution, the supreme court, and the idea that anyone can stop them from doing anything they want www.theatlantic.com/politics/arc...theatlantic.comThe Constitutional Crisis Is HereThe Supreme Court told the Trump administration to “facilitate” the return of Kilmar Abrego Garcia from El Salvador’s infamous CECOT prison. So far, the administration is pretending to comply while re... 21377842913
Reposted by Mike LeeAaron Rupar @atrupar.com · 01/04/2025🔥 @ninajankowicz.com: "Mr Taibbi said when he was first searching through the so-called Twitter files he didn't know what he was looking at. Well, he still doesn't. Everything looks like a conspiracy when you don't know how anything works." 168165773342
Reposted by Mike LeeRachael Sirianni, PhD @docsirianni.bsky.social · 31/03/2025Here, with breakdown by type of F award. These kinds of training grants are essential to support the academic workforce pipeline. These grants are paying the salaries of the ppl who do the work 1174
Reposted by Mike LeeSolomon @solomonrmissouri.com · 28/03/2025Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2025/03/28/o...nytimes.comOpinion | Hillary Clinton: This Is Just Dumb (Gift Article)The Signal group chat is only the latest in a string of self-inflicted wounds by the new administration. 03820
Reposted by Mike LeeDavid Burbach 🇺🇸 @dburbach.bsky.social · 26/03/2025JFC, Fulbright scholar not accused of any crime, no immigration violation, no reason to expect any violence -- just Marco Rubio's whim -- and instead of summoning her first step is no-uniform / no-ID guys in masks and hoodies grabbing her off a public street. 491213513
Reposted by Mike LeeSean Ryder @seanryderphd.bsky.social · 26/03/2025Six masked agents in street clothes disappearing a Tufts Ph.D. student in broad daylight on the streets of Somerville. There is video footage out there every person should watch. 45644
Reposted by Mike LeeEvan Hill @evanhill.bsky.social · 13/03/2025Some pretty stunning answers here from DHS Deputy Secretary Troy Edgar in today's interview with NPR's Michel Martin, in which Edgar equates pro-Palestinian protests with terrorist activity and can't point to any crime committed by Mahmoud Khalil: npr.org/2025/03/13/n... 751545619
Reposted by Mike LeeSherry Pagoto, PhD @drsherrypagoto.bsky.social · 12/03/2025New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024. That's not to mention the countless lives that biomedical research has saved. Show me a better investment than that. www.forbes.com/sites/michae...forbes.comNIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New ReportNational Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research. 2320231138
Reposted by Mike LeeJohn Wallingford @jbwallingford.bsky.social · 24/02/2025Data for every State can be found here: 3/3 www.unitedformedicalresearch.org/nih-in-your-...unitedformedicalresearch.orgNIH In Your State - United For Medical ResearchSelect a state on the map to see the impact of NIH funding across America. 0132
Reposted by Mike LeeSenator Patty Murray @murray.senate.gov · 24/02/2025By crushing cancer research, what are Elon & Trump making more efficient? Their NIH funding cuts are illegal—so instead, they're suffocating the grant approval process for cancer researchers with so much red tape that labs & clinical trials will be forced to shut down. 31362126
Reposted by Mike LeeBlossom Damania @damania.bsky.social · 24/02/2025NIH funding creates medicines, jobs and economic growth 12014
Mike Lee @theleelab.bsky.social · 13/12/2024We just posted a preprint about a death mechanism that we find truly surprising. When you turn off transcription, cells die (duh!)... but did you know this happens due to loss of Pol II itself, not loss of Pol II activity!?! preprint here and a thread (1/n): www.biorxiv.org/content/10.1... 🧪biorxiv.orgPol II degradation activates cell death independently from the loss of transcriptionPol II-mediated transcription is essential for eukaryotic life. While loss of transcription is thought to be universally lethal, the associated mechanisms promoting cell death are not yet known. Here,... 310129
Reposted by Mike LeeIvano Amelio @ivanoamelio.bsky.social · 16/11/2024Let's bring the #CellDeath community together here on 🦋 Just get in touch to join this Starter Pack go.bsky.app/R6mGrKU 176144