iiinova — where your digital self keeps evolving

Ronan Kapetanovic @ronankp.bsky.social · 25/04/2026

Our work is finally out in Science Immunology ! This was an Amazing collaborative work from all co-authors, in particular the two co-first authors James Curson and Syeda Farhana Afroz . Never give up ! :) www.science.org/doi/10.1126/...

science.org

Mitochondrial fission mediates an evolutionarily conserved antibacterial defense response

Mitochondrial fission promotes antibacterial defense via the mitochondrial unfolded protein response and inducible lipid droplets.

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Ronan Kapetanovic @ronankp.bsky.social · 01/07/2025

Went to basel last week for a Farewell Seminar for Patrick Matthias at the FMI. Really enjoyed meeting old alumni of Patrick’s lab. Enjoy your new adventure Patrick!!

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Reposted by Ronan Kapetanovic

Isabelle Virlogeux-Payant @ipayant.bsky.social · 21/03/2025

Happy to share our last paper. We show that the inoculation of 4 commensal bacteria to chicks has both short- and long-term effects on immune response and microbiota composition and promoted the low-shedder phenotype thanks to a more fermentative microbiota. www.tandfonline.com/doi/full/10....

tandfonline.com

The immune response modulated by inoculation of commensal bacteria at birth impacts the gut microbiota and prevents Salmonella colonization

Super- and low-shedding phenomena have been observed in genetically homogeneous hosts infected by a single bacterial strain. To decipher the mechanisms underlying these phenotypes, we conducted an ...

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Ronan Kapetanovic @ronankp.bsky.social · 27/03/2025

We are looking for a PhD candidate starting on the 01-10-2025. The project aims to understand how the host cells use copper and oxidative species to fight Salmonella infection and how this pathogen evades this antimicrobial response. SHORT DEADLINE ! 20-04-2025 jobs.inrae.fr/en/ot-25517

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Ronan Kapetanovic @ronankp.bsky.social · 21/11/2024

First snow this year in Touraine, France at my workplace (it’s been a few years without I heard)! Cold 🥶 but so happy to see some snow ⛄️

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Ronan Kapetanovic @ronankp.bsky.social · 19/11/2024

Nice work from @laurenpalmer.bsky.social ! Showing once more the important link between zinc, inflammation and antimicrobial response, Here, Acinetobacter baumannii.

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Reposted by Ronan Kapetanovic

Isabelle Virlogeux-Payant @ipayant.bsky.social · 14/11/2024

Perfect project for a post-doc! You will have access to a great set of data and we have already exciting hypotheses! Don’t hesitate to contact us.

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Ronan Kapetanovic @ronankp.bsky.social · 13/11/2024

Looking for PostDoc - Metabolism/Salmonella. We are looking for candidates with excellent knowledge in bioinformatics and bacterial physiology / microbial ecology. We will help the candidate to build a successful application for European grants such as EMBO and Marie Skłodowska-Curie Actions.

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Ronan Kapetanovic @ronankp.bsky.social · 13/11/2024

With all the new people, perhaps I should post an introduction. I am an immunologist identifying new antimicrobial responses in macrophages. My current research focuses on the use of metal ions (Zn & Cu) vs Salmonella infection. Always love to meet new faces and set up new collaborations. 🔬🦠

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Ronan Kapetanovic @ronankp.bsky.social · 19/09/2024

It’s out ! Our review on antibacterial responses in macrophages in @NatRevImmunol . We tried to cover as many pathways as we can, macrophages always astonish me by their immense arsenal. Very happy to have collaborated on that paper ! Version online FREE: rdcu.be/dUlUZ

rdcu.be

Inducible antibacterial responses in macrophages

Nature Reviews Immunology - Macrophages are innate immune sentinels providing frontline defence against infection. This Review describes the inducible mechanisms used by macrophages to kill...

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Ronan Kapetanovic @ronankp.bsky.social · 18/04/2024

Good News ! We are looking for a PhD student to work on understanding the role of zinc in the host response to Salmonella. How macrophage use the Zn? How Salmonella resist Zn and can escape this antimicrobial weapon? Deadline 31.05.24 to start 01-10-2024. jobs.inrae.fr/en/ot-21883

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Ronan Kapetanovic @ronankp.bsky.social · 21/02/2024

Super stoke with the publication of this work ! Amazing job from @KaustavDasGupt8 and James to carry out the work ! How the heavy metal zinc is linked to antimicrobial response in CF patients. doi.org/10.1073/pnas...

doi.org

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

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Ronan Kapetanovic @ronankp.bsky.social · 17/02/2024

Music Brings People Together 🎶 A nice project from one of my friends to establish his awesome Music School close to Tours, France. Every little donation is worth a lot for them ! www.kisskissbankbank.com/fr/projects/...

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Ronan Kapetanovic @ronankp.bsky.social · 09/02/2024

Last few days before deadline!

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Ronan Kapetanovic @ronankp.bsky.social · 14/01/2024

Biology is never simple ! I’m happy to share our new publication on the role of HDAC6 on inflammasome. We used several methods (KO mouse, inhibitors, DARPIN…) to show that HDAC6 is NOT always driving the inflammasome and is context-dependent. DOI:https://doi.org/10.1016/j.jbc.2024.105638

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Ronan Kapetanovic @ronankp.bsky.social · 14/01/2024

Good news ! I’m looking for a post-doc (1 year ½ contract) to join our MiMoSa team at the @INRAE_VDL . Host-pathogen interaction project on understanding the dynamic of Zn and Cu during Salmonella infection. Deadline: Feb 11th, 2024. jobs.inrae.fr/en/ot-19561

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Ronan Kapetanovic @ronankp.bsky.social · 25/10/2023

I finally made it onto BlueSky ! I'm rebuilding my network slowly. I will try to update regularly my profile with (mostly) science while setting up my research at the INRAE ! Macrophages, Salmonella, metal ions (zinc) & mitochondria

Activated macrophages displaying zinc vesicles

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