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Teresa Mastracci

@teresamastracci.bsky.social
1.2K followers 188 following 12 posts

Associate Professor, Department of Biology @ Indiana University Indianapolis @iuibiology.bsky.social My lab focuses on diabetes & rare disease research. Science enthusiast. Proudly 🇨🇦

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Reposted by Teresa Mastracci
Robert Screaton @roblab.bsky.social · 15/04/2026
Today in the 🇨🇦 grad course in islet biology and diabetes we are joined by experts @rlhull-meichle.bsky.social and @teresamastracci.bsky.social for a discussion of context and cues: islets in a sea of acini!
media.tenor.com
a man in a wetsuit is floating in the ocean with his hand up
ALT: a man in a wetsuit is floating in the ocean with his hand up
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Teresa Mastracci @teresamastracci.bsky.social · 07/05/2025
Congratulations to Dr. Al Powers — recognized with the Lacy Medal Award at the Midwest Islet Club meeting. So incredibly well deserved!! My scientific career was greatly impacted by you — so very thankful for your time and mentorship, Al! #MIC2025
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Reposted by Teresa Mastracci
Robert Screaton @roblab.bsky.social · 23/04/2025
Fantastic talks just now from experts @teresamastracci.bsky.social and @rlhull-meichle.bsky.social on crosstalk between the #islet and the surrounding #acinar and vascular tissue... are there novel pancreatic targets outside the islet to treat #T1D and #T2D? 🇨🇦 Nat'l Grad Course @uoft.bsky.social
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Daniel Drucker @danieljdrucker.bsky.social · 13/03/2025
Some thoughts on the new dynamic uncertain status and need for US-Canada Science diplomacy www.science.org/doi/10.1126/...
science.org
Uphold US-Canada science
A partnership can be demanding, and as with any couple, can have good days and bad. The United States–Canada relationship is most definitely having a bad one. It’s difficult to fully comprehend all th...
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Mark Carney @mark-carney.bsky.social · 09/03/2025
Thank you. We're strongest when we are united.
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Denis Wirtz @deniswirtz.bsky.social · 09/03/2025
As federal funding for research is uncertain, we need to diversify funding sources for our PhD students. Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies. Download it here: research.jhu.edu/rdt/funding-...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 08/03/2025
Although obesity & a sedentary lifestyle are considerable contributors, research over the last 25 years has shown that type 2 #diabetes develops on a predisposing #genetic background, with family & twin studies indicating considerable heritability thelancet.com/journals/lan... #T2D #MedSky #EndoSky
thelancet.com
Dissection of type 2 diabetes: a genetic perspective
Diabetes is a leading cause of global mortality and disability, and its economic burden is substantial. This Review focuses on type 2 diabetes, which makes up 90–95% of all diabetes cases. Type 2 diab...
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Teresa Mastracci @teresamastracci.bsky.social · 07/03/2025
We stand up for science!!
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Reposted by Teresa Mastracci
Gabriel Bosslet @gbosslet.bsky.social · 07/03/2025
Indy killed it @standupforscience.bsky.social
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Teresa Mastracci @teresamastracci.bsky.social · 05/03/2025
Thank you #nPOD — I remain speechless!! this meeting never disappoints and has become one that I look forward to every year to challenge thinking, expand my love of science (if that’s even possible!) and remind me of the warmth and generosity of friends and colleagues #nPOD2025 #sciencematters
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Cell Metabolism @cp-cellmetabolism.bsky.social · 04/03/2025
On #WorldObesityDay 2025 we present a special focus issue: "Decoding the complex systems of obesity”. We explore organ cooperation, metabolic health & environmental factors like diet in obesity. www.cell.com/cell-metabol...
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allen institute @alleninstitute.org · 03/03/2025
✋🛑 Scroll Checkpoint! Feeling a little stressed? Give your mind a break with some ✨ Soothing Science ✨ featuring one of our stem cell lines. 🔊 Sound on for some tranquil audio 🧪
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Denis Wirtz @deniswirtz.bsky.social · 03/03/2025
Some good news: The Federal Register has just posted NIH study sections, which are to meet in late March. NIH announces some key grant-review meetings will restart in late March | Science | AAAS www.science.org/content/arti...
science.org
NIH announces some key grant-review meetings will restart in late March
Trump policy blocking required notices has frozen reviews of thousands of grants
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Teresa Mastracci @teresamastracci.bsky.social · 19/02/2025
New publication from the #Mastracci lab,which outlines 2 techniques that measure changes in mRNA #translation: polysome profiling and puromycin incorporation. We have detailed step-by-step protocols, including all the needed reagents to execute these techniques! www.sciencedirect.com/science/arti...
sciencedirect.com
Analysis of translational regulation using polysome profiling and puromycin incorporation
Translation is the process of decoding an mRNA transcript to permit the synthesis of a protein. This process occurs in three steps: initiation, elonga…
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Francis Lynn 🇨🇦 @nictitate.bsky.social · 15/02/2025
I have funding through at least 2031 for postdoctoral researchers with expertise in islet biology or cell-based therapies for, or modelling of, diabetes. Bring your expertise to a country that values it. 🇨🇦 Contact info on my website.
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Mark Carney @mark-carney.bsky.social · 15/02/2025
When people see the maple leaf, they see possibility. They see freedom. They see a helping hand. They see Canada, and the best of our values. Happy 60th to our flag. 🇨🇦
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International Society of Developmental Biology @isdb.bsky.social · 14/02/2025
Happy #ValentinesDay to all of our beloved developmental biologists from the ISDB team. Here is a heart made out of some migrating immune cells. It's only right that they are in pink. Do you spot another heart somewhere in the photo? 😌 💗
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Dylan Burnette @mag2art.bsky.social · 14/02/2025
Neuronal growth cones videoed through a differential interference contrast (DIC) microscope. #CellBiology #Science #Biology #microscopy
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Jeremy Berg @jeremymberg.bsky.social · 10/02/2025
A useful tool and a great thing to do... 5calls.org/issue/nih-ns...
5calls.org
Save NIH and NSF Research Funding ⭑ 5 Calls
On February 7, the Trump administration moved to cut billions of dollars in funding from the National Institutes of Health (NIH) and National Science …
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Mark Cuban @mcuban.bsky.social · 09/02/2025
This is the most relevant article to NIH and research cuts I’ve seen. Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !” globalnews.ca/news/9793403...
globalnews.ca
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
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NEJM.org @nejm.org · 08/02/2025
A 𝗻𝗲𝘂𝗿𝗮𝗹 𝗰𝗿𝗲𝘀𝘁 is a group of ectodermal cells that are pinched off during neural tube closure. The neural crest migrates to various locations to contribute to diverse tissues, including melanocytes, craniofacial bones, and peripheral-nerve ganglia. #MedSky #ScienceSky
Visual representation of "neural crest."
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James Briscoe @jamesbriscoe.bsky.social · 05/02/2025
ICYMI: Commentary on "mechanism" in dev bio Ozpolat et al argue for diverse approaches to mechanism - from molecular to systems level journals.biologists.com/dev/article/...
journals.biologists.com
A case for broadening our view of mechanism in developmental biology
ABSTRACT. Developmental biologists can perform studies that describe a phenomenon (descriptive work) and/or explain how the phenomenon works (mechanistic work). There is a prevalent perception that mo...
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Angelo Iulianella @aineurolab.bsky.social · 05/02/2025
A blue sky with moon at #Bluesky. Astrophotography at daytime for a cleanse.
Half-moon in the daytime.
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John Wallingford @jbwallingford.bsky.social · 04/02/2025
Birth defects are the #1 cause of death in the first year of life (🧵). Birth defects kill more than twice as many children as cancer. Birth defects are diseases of developmental biology. Here are CDC statistics for 2021. 1/5 wisqars.cdc.gov/pdfs/leading...
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Richard Behringer @rrbehringer.bsky.social · 01/02/2025
Here is the 2025 embryo alphabet from alligator to zebrafish. Developmental biology is stunning & leads to important discoveries for human medicine. @socdevbio.bsky.social
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Teresa Mastracci @teresamastracci.bsky.social · 25/01/2025
I will defend the importance of science until I’m blue in the face. As a society we need science to help us maintain health and resolve disease but we also need it to answer the simple everyday questions that can make our lives easier and happier. Case in point…. arxiv.org/abs/2501.00536
arxiv.org
Phase behavior of Cacio and Pepe sauce
"Pasta alla Cacio e pepe" is a traditional Italian dish made with pasta, pecorino cheese, and pepper. Despite its simple ingredient list, achieving the perfect texture and creaminess of the sauce can ...
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Space VFX @spacevfx.bsky.social · 17/01/2025
Presenting the Eighth Wonder of the World: The Rainbow Nebulae, a symbol of hope and inclusivity. A celestial masterpiece formed by interstellar gases and cosmic dust, spreading vibrant hues across the universe. Author: @venusianchron.bsky.social
A stunning cosmic landscape featuring two prominent nebulae with radiant colors—reds, oranges, yellows, and blues, contrasting against the dark expanse of space. Twinkling stars fill the background, while wispy tendrils of gas and dust form intricate, organic patterns, adding depth and texture. This artwork falls under the genre of Astronomical and Space art.
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Development @dev-journal.bsky.social · 18/01/2025
Positive autoregulation of Sox17 is necessary for gallbladder and extrahepatic bile duct formation Read this #OpenAccess Research Article by Linh Trinh, Ryan Finnel, Mark Magnuson and colleagues @vanderbilt.edu: journals.biologists.com/dev/article…
Figure 5 Sox17mut5/mut5 GB epithelium displays metaplastic changes. (A) Hematoxylin and eosin (H&E) and AB-PAS staining of WT Sox17+/+ and Sox17mut5/mut5 GBs. Asterisks indicate intramural gland-like and crypt-like structures within Sox17mut5/mut5 GB epithelium. The structures contain gastric pyloric-type gland cells producing neutral mucins stained red (arrowhead) and intestinal goblet-like cells producing acidic mucins stained blue (arrows). (B) Immunofluorescent staining of Sox17+/+ and Sox17mut5/mut5 GBs with antibodies against epithelial cell marker EPCAM (green) and intestinal goblet cell marker TFF3 (red), with nuclei stained with TO-PRO3 (blue). Arrows indicate TFF3+ goblet-like cells within Sox17mut5/mut5 GB epithelium. Scale bars: 50 μm.
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Teresa Mastracci @teresamastracci.bsky.social · 10/12/2024
IU Indianapolis School of Science announced a $1 million endowment to establish the Simon J. Rhodes Legacy Scholarship. Dr. Rhodes is an unwavering supporter of trainees at all levels! Preference will be given to IPS students or those from Marion County,IN science.indianapolis.iu.edu/about/news/a...
science.indianapolis.iu.edu
School of Science announces $1 million endowment in honor of former Dean: : News: About: School of Science: Indiana University IndianapolisIU Trident
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W. Brent Derry @wbderry.bsky.social · 07/12/2024
If you want to learn about how a tiny worm led to major insights in developmental biology and human disease check out the Nobel lectures from Victor Ambros and Gary Ruvkun. www.youtube.com/watch?v=VQ9N...
youtube.com
2024 Nobel Prize lectures in physiology or medicine | Victor Ambros and Gary Ruvkun
YouTube video by Nobel Prize
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Jon Lim, FRCP PhD @drjonlim.bsky.social · 23/11/2024
🎨 In case anyone need… The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏! Check it out 👇 bioart.niaid.nih.gov
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Teresa Mastracci @teresamastracci.bsky.social · 26/11/2024
As always, beautiful work from the lab of @heikolickert.bsky.social. Give it a read — you wont be disappointed. www.nature.com/articles/s42...
nature.com
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
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Teresa Mastracci @teresamastracci.bsky.social · 20/11/2024
If you have interest in #pancreatic diseases then this is the meeting for you!! Join us in Maine in June 2025
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Teresa Mastracci @teresamastracci.bsky.social · 19/11/2024
Who doesn’t love talking #islet biology??!!!
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Teresa Mastracci @teresamastracci.bsky.social · 21/10/2023
I’m simultaneously inspired and mentally exhausted! What an incredible two days of #science chats with old and new friends. Thank you so much Danielle Dean for organizing a jam packed schedule @ Vanderbilt U and thank you to everyone that made time to meet and come to my talk
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