Reposted by Steven MathernMatt Siuba @zentensivist.bsky.social · 20/05/2025Interface paper is now published www.mdpi.com/2075-4426/15... 1223
Reposted by Steven MathernChise @sailorrooscout.bsky.social · 15/05/2025GOOD NEWS! Researchers have found that getting vaccinated against shingles- a painful and debilitating condition that can flare up years after infection from VZV- not only LOWERS the risk of infection, but can also PROTECT against dementia and REDUCE the risk of cardiovascular disease! 🧪🧵⬇️ 682528729
Reposted by Steven Mathernjosh farkas 💊 @pulmcrit.bsky.social · 11/05/2025did you think that labetalol is a single drug? nope it’s actually a mixture of FOUR different drugs RS, RR, SS, and SR-labetalol and this is clinically relevant! lets discuss why… 🧵 #1/3 #EMIMCC 23111
Reposted by Steven MathernIan Weissman, DO @drianweissman.bsky.social · 11/05/2025For many experts, Health. Secretary Kennedy’s promise to find autism’s causes in a few months is jarring — and unrealistic. That’s because it appears to ignore decades of science linking about 200 genes that play a role. apnews.com/article/auti...apnews.comExperts call Kennedy's plan to find autism's cause unrealisticMany autism experts say the Trump administration's plan to find autism's causes is unrealistic. Health Secretary Robert F. 1213134
Reposted by Steven MathernEdward Nirenberg @enirenberg.bsky.social · 06/05/2025tl;dr- egotistical edgelord intoxicatingly enamored with the (false) idea that he's far smarter than everyone else and therefore superiorstatnews.comVinay Prasad, in his own words, outlines the philosophy he’ll bring to the FDAVinay Prasad, tapped to be a top official at the FDA, has never shied from speaking his mind. 910120
Reposted by Steven MathernThelonevirologist @thelonevirologist.bsky.social · 06/05/2025Texas measles total tops 700 cases amid rises in other states www.cidrap.umn.edu/measles/texa...cidrap.umn.eduTexas measles total tops 700 cases amid rises in other statesAlso, health departments in Illinois, North Dakota, and Missouri reported more measles cases. 031
Reposted by Steven MathernDr Lipid @drlipid.bsky.social · 05/05/202520 years after it was approved, cardiologists are recognizing that ezetimibe is a great statin helper www.msn.com/en-us/health/other/cardiologists-say-statin-combination-therapy-can-reduce-cholesterol-related-deaths-by-49/ar-AA1CKN9r?ocid=msedgntp&pc=DCTS&cvid=77de09834e2542b09bdbdbf88b12fbac&ei=11 0103
Reposted by Steven MathernᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 02/05/2025Most vaccines don’t trigger mucosal IgA—a key airway defense Clever new Nat Comm study from 🇳🇴 solves that by fusing antigens to albumin, which uses FcRn pathway to cross the nasal barrier Result: a potent intranasal vaccine that protects vs. both flu and SARS-CoV-2 www.nature.com/articles/s41... 39132
Reposted by Steven MathernVoices for Vaccines @voices4vaccines.bsky.social · 02/05/2025www.voicesforvaccines.org/jtf_topics/d...voicesforvaccines.orgDo vaccines contain aborted fetuses?Do vaccines contain aborted fetuses? No—some use decades-old fetal cell lines for development, but no new cells are used. Learn the facts behind this persistent myth. 0107
Reposted by Steven MathernAntibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 01/05/2025🆕🔥 State of the art review article @cmicomms.bsky.social Approach to Clostridioides difficile Diarrheal Infection ( CDI) Excellent discussions about the management of CDI #IDsky #mustread www.sciencedirect.com/science/arti... 2206
Reposted by Steven MathernMark Cuban Cost Plus Drug Company @costplusdrugs.com · 01/05/2025🪪 𝐖𝐡𝐚𝐭 𝐢𝐬 teamcubancard.com? Team Cuban Card is a free program that brings the same transparent pricing you know from Cost Plus Drugs to local pharmacies across the country. Just download your card, check available medications, and find a participating pharmacy near you. 13810
Reposted by Steven MathernEdward Nirenberg @enirenberg.bsky.social · 01/05/2025Also given our HHS Secretary's comments about fetal cells in vaccines... here's a post I made about that: open.substack.com/pub/deplatfo... 1218
Reposted by Steven MathernMatt Wynia @mattwynia.bsky.social · 01/05/2025Cool table from @bradspellberg.bsky.social of RCTs of vaccines, in case anyone honestly believes there have been no RCTs of today's routine childhood vaccines: www.bradspellberg.com/vaccine-rctsbradspellberg.comVaccine RCTs | mysite 059
Reposted by Steven MathernAntibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 01/05/2025🆕🔥Case-control study @bradspellberg.bsky.social Just 1/4 blood cultures positive (≥2 sets drawn) or early clearance → low IE probability. Persistent bacteremia or 4/4 bottles ↑ pretest probability Simple bedside clues to sharpen your endocarditis game. #IDSky #EMIMCC jamanetwork.com/journals/jam... 1187
Reposted by Steven MathernPaul Kingsley @paulkingsley7.bsky.social · 02/05/2025Just found Dr. Hotez here on Bluesky. 20,000 of you already knew he was here. Great follow. bsky.app/profile/pete...bsky.app 35510
Reposted by Steven MathernLuis Ostrosky, MD, FIDSA @drluiso.bsky.social · 30/04/2025"most areas do not have experts in mycology" #IDSky @msgerc.bsky.social www.idse.net/Fungal-Infec...idse.netCosmetic Plastic Surgery Meningitis Mexico Mommy MakeoverTwenty-four patients who underwent cosmetic surgeries during 2023 in two clinics in Mexico developed <em>Fusarium solani </em>meningitis. 183
Reposted by Steven MathernJACC Journals @jaccjournals.bsky.social · 30/04/2025This #FINEHEART pooled analysis, published in #JACC, demonstrated that finerenone significantly reduced the risk of new-onset atrial fibrillation/atrial flutter across the CKM spectrum. www.jacc.org/doi/10.1016/... #AFibjacc.orgFinerenone Reduces New-Onset Atrial Fibrillation Across the Spectrum of Cardio-Kidney-Metabolic Syndrome: The FINE-HEART Pooled Analysis 156
Steven Mathern @stevenmathern.bsky.social · 30/04/2025'Lipid-related atherosclerotic risk is most accurately reflected by the total count of apoB-P and is largely unaffected by the major particle type (VLDL, LDL) or size. Elevated count of Lp(a) adds additional risk' #apob #lpa apo(b) apolipoprotein b #ldl #cholesterol academic.oup.com/eurheartj/ad...academic.oup.comApoB-containing lipoproteins: count, type, size, and risk of coronary artery diseaseAbstractBackground and Aims. Apolipoprotein B concentration reflects the number of atherogenic lipoproteins and is recognized as a key lipid risk marker. W 042
Steven Mathern @stevenmathern.bsky.social · 30/04/2025'Defining and subphenotyping ARDS' www.sciencedirect.com/science/arti...sciencedirect.comDefining and subphenotyping ARDS: insights from an international Delphi expert panelAlthough the definition of acute respiratory distress syndrome (ARDS) has undergone numerous revisions aimed at enhancing its diagnostic accuracy and … 020
Steven Mathern @stevenmathern.bsky.social · 29/04/2025procedural sedation protocol, versed and ketamine 030
Reposted by Steven MathernBrad Spellberg @bradspellberg.bsky.social · 27/04/2025Updated vaccine RCT table looking amazing! Sorted for vaccine type, now more interactive in table, can click directly on the pubmed links in the table to go to the manuscripts. bradspellberg. www.bradspellberg.com/vaccine-rctsbradspellberg.comVaccine RCTs | mysite 0136
Reposted by Steven Mathern@IM_Crit_ @imcrit.bsky.social · 27/04/2025Yes, actually in one of my responses on Twitter I wrote that I try to keep the tip of the CVC at least 5cm away from the tip of the dialysis catheter 032
Steven Mathern @stevenmathern.bsky.social · 27/04/2025'ensure CVC and, Vascath tips are distanced, to avoid dialysing out meds given via CVC' 010
Reposted by Steven MathernMangesh Kritya @mangeshk.bsky.social · 25/04/2025🔴New publication in the CCI journal!🔴 Grateful to our mentors Dr. Shariq Shamim (@shariqshamimmd.bsky.social) and Dr. Salman Arain for their constant support. Big thanks to @vaibhavsharmamd.bsky.social, @drthayu.bsky.social, and Dr. Sahai! 📖 Full Text: onlinelibrary.wiley.com/share/author...onlinelibrary.wiley.com 255
Steven Mathern @stevenmathern.bsky.social · 21/04/2025'RV dysfunction occurs on VV-ECMO in ARDS despite ECMO mitigating many of the traditional RV dysfunction risk factor' #critcaresky #cccsky #ecmo #vv-ecmo #emimcc 030
Reposted by Steven MathernDr Lipid @drlipid.bsky.social · 21/04/2025I was interviewed for this excellent report in @Jamanews by Jennifer Abassi on the new discovery on apoB /LDL receptors interaction made by the @nih_nhlbi Lipoprotein lab led by Alan Remaley. [NB -it was not I who used the terms good and bad] jamanetwork.com/journals/jam...jamanetwork.comNew Insights On LDL CholesterolThis Medical News article discusses recent landmark work to visualize the structure of the cholesterol-carrying low-density lipoprotein (LDL) particle bound to its cell surface receptor. 1161
Reposted by Steven MathernAlt National Park Service @altnps.bsky.social · 18/04/2025Senator Chris Van Hollen met with Kilmar Armando Abrego Garcia in San Salvador. 💚 18212927819
Reposted by Steven MathernBK. Titanji @boghuma.bsky.social · 17/04/2025“We no longer have all the mechanisms in place to learn from those situations and prevent the next outbreak from happening,” www.yahoo.com/news/deadly-...yahoo.comA deadly E. coli outbreak hit 15 states, but the FDA chose not to publicize itA foodborne illness linked to lettuce ripped across 15 states last November, sickening dozens of people and killing one. But the federal government chose not to publicize it. 46429
Reposted by Steven MathernAlt National Park Service @altnps.bsky.social · 17/04/2025Soon after, DOGE installed a virtual system inside the agency’s servers that operated in secret. This system left no logs, no trace of its activity, and was removed without a record of what had been done. 133575580
Reposted by Steven MathernDr Lipid @drlipid.bsky.social · 17/04/2025Very happy to be one of the contributors to this manuscript discussing a patient's failure to respond to PCSK9 inhibitors. Open access at www.jacc.org/doi/epdf/10.1016/j.jaccas.2025.103696 @nationallipid.bsky.social @aspcardio.bsky.social @familyheartfdn.bsky.social @escardio.bsky.social 085
Reposted by Steven MathernRyan Marino, MD @ryanmarino.bsky.social · 12/04/2025From 1999-2013, RFK sold his own brand of bottled water (in plastic bottles, and with a horrible carbon footprint) that contained TWO TIMES the upper limit of fluoride recommended for dental health, which is more than the safely allowable amount per US Public Health Service, and IS potentially toxicindependent.co.ukRFK Jr used to hawk water with high levels of fluoride. Now he wants to ban itBottled water from RFK Jr’s company Keeper Springs contained almost double the concentration of fluoride recommended by the HHS 391085378
Reposted by Steven MathernDr Lipid @drlipid.bsky.social · 03/01/2025If I had elevated Lp(a), pending new therapies, I would be on a PCSK9i + statin (low dose) + ezetimibe. Since patients have high Lp(a) since birth the mantra needs to be "lower (very much) for longer" is better. NO LONGER ARGUABLE. In such patients I desire LDL-C (apoB) well < 50 mg/dL 2125
Reposted by Steven MathernAntibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 12/04/2025The most anticipated RCT in ID 🔥SNAP RCT🔥The largest RCT 2 date in SA bactermia N:1341 Cefazolin Vs ASPs ((flu)cloxacillin) for MSSA bacteremia Cefazolin is non-inferior (90d mortality)& less AKI than ASPs A practice-changer RCT that must change the guidelines #ESCMIDGlobal #IDSky 27021
Reposted by Steven MathernPaul Kingsley @paulkingsley7.bsky.social · 12/04/2025Colleges enthusiastically participating in arresting students. “Several universities in Florida have signed agreements to cooperate with Immigration and Customs Enforcement amid an ongoing push by state leaders to aid the Trump administration’s crackdown on immigration.” www.cnn.com/2025/04/12/u...cnn.comFlorida universities join statewide push to partner with ICE on immigration enforcement | CNNSeveral universities in Florida have signed agreements to cooperate with Immigration and Customs Enforcement amid an ongoing push by state leaders to aid the Trump administration’s crackdown on immigr... 021
Reposted by Steven MathernThe New York Times @nytimes.com · 12/04/2025Two groups representing Harvard professors sued the Trump administration on Friday, saying that its threat to cut billions in federal funding for the university violates free speech and other First Amendment rights.nytimes.comHarvard Professors Sue Trump Administration Over Threat to Federal FundsThe administration is reviewing about $9 billion in federal funding that the university receives. 471529317
Reposted by Steven MathernRyan Marino, MD @ryanmarino.bsky.social · 12/04/2025Gonna keep repeating this: 1) Fluoride added for dental health (which improves cardiovascular health, neurologic functioning, and more) is NOT toxic. 2) Water with naturally high levels of fluoride (not added, levels are much higher) can be a risk for toxicity. He is going after 1 and ignoring 2. 21614177
Reposted by Steven MathernAlt National Park Service @altnps.bsky.social · 13/04/2025As we’ve warned before, the Trump administration has subjected around 80 staffers to lie detector tests. America, please understand—this is not normal. 289107192805
Reposted by Steven MathernChise @sailorrooscout.bsky.social · 12/04/2025Vaccines save lives. And no, they do not cause autism. 249100122822
Reposted by Steven Mathern@IM_Crit_ @imcrit.bsky.social · 13/04/2025ICU Snapshots: Patient with #COPD exacerbation, on the ventilator. Bad, bad auto-PEEP... #foamed #foamcc #meded #medsky #cccsky #emimcc 052
Reposted by Steven MathernRobert Reich @rbreich.bsky.social · 12/04/2025Trump's EPA just moved to reverse state and local bans on toxic "forever chemicals" that can lead to birth defects and cancer. So much for "Make America Healthy Again." www.theguardian.com/environment/202…theguardian.comTrump officials quietly move to reverse bans on toxic ‘forever chemicals’EPA bids to change chemical risk evaluations, which could expose public to higher levels of PFAS and other pollutants 27439921927
Reposted by Steven Mathernjosh farkas 💊 @pulmcrit.bsky.social · 12/04/2025SNAP trial results reported Cefazolin was the champion for MSSA 🏆 Less nephrotoxicity than flucoxacillin 🏆 Reduced early mortality Not published but I think the answer is clear: Cefazolin now generally 1st line tx for MSSA "Innoculum effect" with nafcillin= debunked Updated IBCC (#1/2) #EMIMCC 3303
Reposted by Steven MathernAngie Rasmussen @angierasmussen.bsky.social · 11/04/2025When I first became reviews editor at Vaccine, my predecessor Kathy Neuzil very kindly gave me advice that I’ve carried into my role as co-EIC. Last year she received the Jenner Award for her contributions to vaccinology. Kathy’s vaccine research & advocacy saved many lives. This is disgraceful. 924074
Reposted by Steven MathernEdward Nirenberg @enirenberg.bsky.social · 11/04/2025you now have to reconsider. A majority of people will not accept paying this cost to being wrong- at least, not in any kind of short-term timeframe. Instead, they will opt for belief perseverance to resolve their cognitive dissonance. 073
Reposted by Steven Mathern@IM_Crit_ @imcrit.bsky.social · 10/04/2025Refresher on Swan-Ganz catheter: 185
Reposted by Steven MathernTimothy McBride @mcbridetd.bsky.social · 11/04/2025U.S. Military Removes Commander of Greenland Base After Vance Visit www.nytimes.com/2025/04/11/w...nytimes.comU.S. Military Removes Commander of Greenland BaseAlthough the military did not say why the colonel had been dismissed, it said it would not tolerate any subversion of President Trump’s agenda. 143
Reposted by Steven MathernDr Lipid @drlipid.bsky.social · 09/04/2025Lipidology Teaching: Ever see an LDLc of 1000 mg/dL? Few have ever heard of Lipoprotein-X. A pathology that mimics but is not FH. What you need to know. If seen, check for hepatobiliary disease. @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social @familyheartfdn.bsky.social 052
Reposted by Steven MathernJACC Journals @jaccjournals.bsky.social · 09/04/2025ICYMI from #ACC25: Dr. Nuccia Morici & colleagues report the results of ALTSHOCK-2, the largest RCT of IABPs in heart failure-related #CardiogenicShock. They found that early IABP implantation did *not* reduce mortality. www.jacc.org/doi/10.1016/... #HeartFailure #CardioSky #ALTSHOCK2jacc.orgEarly Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial 163
Reposted by Steven MathernJAMA @jama.com · 09/04/2025Staphylococcus aureus bacteremia has a case fatality rate of 15% to 30% and causes 300 000 deaths per year worldwide. This Review discusses management of S aureus bacteremia. ➡️ ja.ma/3RF8b50 #MedSky 2359