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Steven Mathern

@stevenmathern.bsky.social
599 followers 344 following 937 posts

#idsky #medsky #cardiosky #pocusky #pocus #CTOPCI #critcaresky #ViroSky #immunology #EmImCc #Epeeps #OMI #EKG #Impella #ECMO #TEER #TAVR #TD-ADR

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Reposted by Steven Mathern
Matt Siuba @zentensivist.bsky.social · 20/05/2025
Interface paper is now published www.mdpi.com/2075-4426/15...
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Reposted by Steven Mathern
Chise @sailorrooscout.bsky.social · 15/05/2025
GOOD NEWS! Researchers have found that getting vaccinated against shingles- a painful and debilitating condition that can flare up years after infection from VZV- not only LOWERS the risk of infection, but can also PROTECT against dementia and REDUCE the risk of cardiovascular disease! 🧪🧵⬇️
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josh farkas 💊 @pulmcrit.bsky.social · 11/05/2025
did you think that labetalol is a single drug? nope it’s actually a mixture of FOUR different drugs RS, RR, SS, and SR-labetalol and this is clinically relevant! lets discuss why… 🧵 #1/3 #EMIMCC
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Ian Weissman, DO @drianweissman.bsky.social · 11/05/2025
For many experts, Health. Secretary Kennedy’s promise to find autism’s causes in a few months is jarring — and unrealistic. That’s because it appears to ignore decades of science linking about 200 genes that play a role. apnews.com/article/auti...
apnews.com
Experts call Kennedy's plan to find autism's cause unrealistic
Many autism experts say the Trump administration's plan to find autism's causes is unrealistic. Health Secretary Robert F.
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Edward Nirenberg @enirenberg.bsky.social · 06/05/2025
tl;dr- egotistical edgelord intoxicatingly enamored with the (false) idea that he's far smarter than everyone else and therefore superior
statnews.com
Vinay Prasad, in his own words, outlines the philosophy he’ll bring to the FDA
Vinay Prasad, tapped to be a top official at the FDA, has never shied from speaking his mind.
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Thelonevirologist @thelonevirologist.bsky.social · 06/05/2025
Texas measles total tops 700 cases amid rises in other states www.cidrap.umn.edu/measles/texa...
cidrap.umn.edu
Texas measles total tops 700 cases amid rises in other states
Also, health departments in Illinois, North Dakota, and Missouri reported more measles cases.
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Dr Lipid @drlipid.bsky.social · 05/05/2025
20 years after it was approved, cardiologists are recognizing that ezetimibe is a great statin helper www.msn.com/en-us/health/other/cardiologists-say-statin-combination-therapy-can-reduce-cholesterol-related-deaths-by-49/ar-AA1CKN9r?ocid=msedgntp&pc=DCTS&cvid=77de09834e2542b09bdbdbf88b12fbac&ei=11
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 02/05/2025
Most vaccines don’t trigger mucosal IgA—a key airway defense Clever new Nat Comm study from 🇳🇴 solves that by fusing antigens to albumin, which uses FcRn pathway to cross the nasal barrier Result: a potent intranasal vaccine that protects vs. both flu and SARS-CoV-2 www.nature.com/articles/s41...
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Voices for Vaccines @voices4vaccines.bsky.social · 02/05/2025
www.voicesforvaccines.org/jtf_topics/d...
voicesforvaccines.org
Do vaccines contain aborted fetuses?
Do vaccines contain aborted fetuses? No—some use decades-old fetal cell lines for development, but no new cells are used. Learn the facts behind this persistent myth.
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Reposted by Steven Mathern
Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 01/05/2025
🆕🔥 State of the art review article @cmicomms.bsky.social Approach to Clostridioides difficile Diarrheal Infection ( CDI) Excellent discussions about the management of CDI #IDsky #mustread www.sciencedirect.com/science/arti...
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Reposted by Steven Mathern
Mark Cuban Cost Plus Drug Company @costplusdrugs.com · 01/05/2025
🪪 𝐖𝐡𝐚𝐭 𝐢𝐬 teamcubancard.com? Team Cuban Card is a free program that brings the same transparent pricing you know from Cost Plus Drugs to local pharmacies across the country. Just download your card, check available medications, and find a participating pharmacy near you.
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Reposted by Steven Mathern
Edward Nirenberg @enirenberg.bsky.social · 01/05/2025
Also given our HHS Secretary's comments about fetal cells in vaccines... here's a post I made about that: open.substack.com/pub/deplatfo...
Fetal tissue use in vaccines [Imported Post from 03/09/2021]
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Matt Wynia @mattwynia.bsky.social · 01/05/2025
Cool table from @bradspellberg.bsky.social of RCTs of vaccines, in case anyone honestly believes there have been no RCTs of today's routine childhood vaccines: www.bradspellberg.com/vaccine-rcts
bradspellberg.com
Vaccine RCTs | mysite
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 01/05/2025
🆕🔥Case-control study @bradspellberg.bsky.social Just 1/4 blood cultures positive (≥2 sets drawn) or early clearance → low IE probability. Persistent bacteremia or 4/4 bottles ↑ pretest probability Simple bedside clues to sharpen your endocarditis game. #IDSky #EMIMCC jamanetwork.com/journals/jam...
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Paul Kingsley @paulkingsley7.bsky.social · 02/05/2025
Just found Dr. Hotez here on Bluesky. 20,000 of you already knew he was here. Great follow. bsky.app/profile/pete...
bsky.app
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Luis Ostrosky, MD, FIDSA @drluiso.bsky.social · 30/04/2025
"most areas do not have experts in mycology" #IDSky @msgerc.bsky.social www.idse.net/Fungal-Infec...
idse.net
Cosmetic Plastic Surgery Meningitis Mexico Mommy Makeover
Twenty-four patients who underwent cosmetic surgeries during 2023 in two clinics in Mexico developed <em>Fusarium solani </em>meningitis.
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Reposted by Steven Mathern
JACC Journals @jaccjournals.bsky.social · 30/04/2025
This #FINEHEART pooled analysis, published in #JACC, demonstrated that finerenone significantly reduced the risk of new-onset atrial fibrillation/atrial flutter across the CKM spectrum. www.jacc.org/doi/10.1016/... #AFib
jacc.org
Finerenone Reduces New-Onset Atrial Fibrillation Across the Spectrum of Cardio-Kidney-Metabolic Syndrome: The FINE-HEART Pooled Analysis
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Steven Mathern @stevenmathern.bsky.social · 30/04/2025
'Lipid-related atherosclerotic risk is most accurately reflected by the total count of apoB-P and is largely unaffected by the major particle type (VLDL, LDL) or size. Elevated count of Lp(a) adds additional risk' #apob #lpa apo(b) apolipoprotein b #ldl #cholesterol academic.oup.com/eurheartj/ad...
academic.oup.com
ApoB-containing lipoproteins: count, type, size, and risk of coronary artery disease
AbstractBackground and Aims. Apolipoprotein B concentration reflects the number of atherogenic lipoproteins and is recognized as a key lipid risk marker. W
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Steven Mathern @stevenmathern.bsky.social · 30/04/2025
'Defining and subphenotyping ARDS' www.sciencedirect.com/science/arti...
sciencedirect.com
Defining and subphenotyping ARDS: insights from an international Delphi expert panel
Although the definition of acute respiratory distress syndrome (ARDS) has undergone numerous revisions aimed at enhancing its diagnostic accuracy and …
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Steven Mathern @stevenmathern.bsky.social · 29/04/2025
procedural sedation protocol, versed and ketamine
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Brad Spellberg @bradspellberg.bsky.social · 27/04/2025
Updated vaccine RCT table looking amazing! Sorted for vaccine type, now more interactive in table, can click directly on the pubmed links in the table to go to the manuscripts. bradspellberg. www.bradspellberg.com/vaccine-rcts
bradspellberg.com
Vaccine RCTs | mysite
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@IM_Crit_ @imcrit.bsky.social · 27/04/2025
Yes, actually in one of my responses on Twitter I wrote that I try to keep the tip of the CVC at least 5cm away from the tip of the dialysis catheter
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Steven Mathern @stevenmathern.bsky.social · 27/04/2025
'ensure CVC and, Vascath tips are distanced, to avoid dialysing out meds given via CVC'
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Mangesh Kritya @mangeshk.bsky.social · 25/04/2025
🔴New publication in the CCI journal!🔴 Grateful to our mentors Dr. Shariq Shamim (@shariqshamimmd.bsky.social) and Dr. Salman Arain for their constant support. Big thanks to @vaibhavsharmamd.bsky.social, @drthayu.bsky.social, and Dr. Sahai! 📖 Full Text: onlinelibrary.wiley.com/share/author...
onlinelibrary.wiley.com
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Steven Mathern @stevenmathern.bsky.social · 21/04/2025
'RV dysfunction occurs on VV-ECMO in ARDS despite ECMO mitigating many of the traditional RV dysfunction risk factor' #critcaresky #cccsky #ecmo #vv-ecmo #emimcc
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Dr Lipid @drlipid.bsky.social · 21/04/2025
I was interviewed for this excellent report in @Jamanews by Jennifer Abassi on the new discovery on apoB /LDL receptors interaction made by the @nih_nhlbi Lipoprotein lab led by Alan Remaley. [NB -it was not I who used the terms good and bad] jamanetwork.com/journals/jam...
jamanetwork.com
New Insights On LDL Cholesterol
This Medical News article discusses recent landmark work to visualize the structure of the cholesterol-carrying low-density lipoprotein (LDL) particle bound to its cell surface receptor.
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Alt National Park Service @altnps.bsky.social · 18/04/2025
Senator Chris Van Hollen met with Kilmar Armando Abrego Garcia in San Salvador. 💚
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BK. Titanji @boghuma.bsky.social · 17/04/2025
“We no longer have all the mechanisms in place to learn from those situations and prevent the next outbreak from happening,” www.yahoo.com/news/deadly-...
yahoo.com
A deadly E. coli outbreak hit 15 states, but the FDA chose not to publicize it
A foodborne illness linked to lettuce ripped across 15 states last November, sickening dozens of people and killing one. But the federal government chose not to publicize it.
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Alt National Park Service @altnps.bsky.social · 17/04/2025
Soon after, DOGE installed a virtual system inside the agency’s servers that operated in secret. This system left no logs, no trace of its activity, and was removed without a record of what had been done.
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Dr Lipid @drlipid.bsky.social · 17/04/2025
Very happy to be one of the contributors to this manuscript discussing a patient's failure to respond to PCSK9 inhibitors. Open access at www.jacc.org/doi/epdf/10.1016/j.jaccas.2025.103696 @nationallipid.bsky.social @aspcardio.bsky.social @familyheartfdn.bsky.social @escardio.bsky.social
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Ryan Marino, MD @ryanmarino.bsky.social · 12/04/2025
From 1999-2013, RFK sold his own brand of bottled water (in plastic bottles, and with a horrible carbon footprint) that contained TWO TIMES the upper limit of fluoride recommended for dental health, which is more than the safely allowable amount per US Public Health Service, and IS potentially toxic
independent.co.uk
RFK Jr used to hawk water with high levels of fluoride. Now he wants to ban it
Bottled water from RFK Jr’s company Keeper Springs contained almost double the concentration of fluoride recommended by the HHS
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Dr Lipid @drlipid.bsky.social · 03/01/2025
If I had elevated Lp(a), pending new therapies, I would be on a PCSK9i + statin (low dose) + ezetimibe. Since patients have high Lp(a) since birth the mantra needs to be "lower (very much) for longer" is better. NO LONGER ARGUABLE. In such patients I desire LDL-C (apoB) well < 50 mg/dL
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 12/04/2025
The most anticipated RCT in ID 🔥SNAP RCT🔥The largest RCT 2 date in SA bactermia N:1341 Cefazolin Vs ASPs ((flu)cloxacillin) for MSSA bacteremia Cefazolin is non-inferior (90d mortality)& less AKI than ASPs A practice-changer RCT that must change the guidelines #ESCMIDGlobal #IDSky
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Paul Kingsley @paulkingsley7.bsky.social · 12/04/2025
Colleges enthusiastically participating in arresting students. “Several universities in Florida have signed agreements to cooperate with Immigration and Customs Enforcement amid an ongoing push by state leaders to aid the Trump administration’s crackdown on immigration.” www.cnn.com/2025/04/12/u...
cnn.com
Florida universities join statewide push to partner with ICE on immigration enforcement | CNN
Several universities in Florida have signed agreements to cooperate with Immigration and Customs Enforcement amid an ongoing push by state leaders to aid the Trump administration’s crackdown on immigr...
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The New York Times @nytimes.com · 12/04/2025
Two groups representing Harvard professors sued the Trump administration on Friday, saying that its threat to cut billions in federal funding for the university violates free speech and other First Amendment rights.
nytimes.com
Harvard Professors Sue Trump Administration Over Threat to Federal Funds
The administration is reviewing about $9 billion in federal funding that the university receives.
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Ryan Marino, MD @ryanmarino.bsky.social · 12/04/2025
Gonna keep repeating this: 1) Fluoride added for dental health (which improves cardiovascular health, neurologic functioning, and more) is NOT toxic. 2) Water with naturally high levels of fluoride (not added, levels are much higher) can be a risk for toxicity. He is going after 1 and ignoring 2.
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Alt National Park Service @altnps.bsky.social · 13/04/2025
As we’ve warned before, the Trump administration has subjected around 80 staffers to lie detector tests. America, please understand—this is not normal.
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Chise @sailorrooscout.bsky.social · 12/04/2025
Vaccines save lives. And no, they do not cause autism.
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@IM_Crit_ @imcrit.bsky.social · 13/04/2025
ICU Snapshots: Patient with #COPD exacerbation, on the ventilator. Bad, bad auto-PEEP... #foamed #foamcc #meded #medsky #cccsky #emimcc
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Robert Reich @rbreich.bsky.social · 12/04/2025
Trump's EPA just moved to reverse state and local bans on toxic "forever chemicals" that can lead to birth defects and cancer.  So much for "Make America Healthy Again." www.theguardian.com/environment/202…
theguardian.com
Trump officials quietly move to reverse bans on toxic ‘forever chemicals’
EPA bids to change chemical risk evaluations, which could expose public to higher levels of PFAS and other pollutants
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josh farkas 💊 @pulmcrit.bsky.social · 12/04/2025
SNAP trial results reported Cefazolin was the champion for MSSA 🏆 Less nephrotoxicity than flucoxacillin 🏆 Reduced early mortality Not published but I think the answer is clear: Cefazolin now generally 1st line tx for MSSA "Innoculum effect" with nafcillin= debunked Updated IBCC (#1/2) #EMIMCC
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Mr. Spock 🖖 @spockresists.bsky.social · 11/04/2025
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Angie Rasmussen @angierasmussen.bsky.social · 11/04/2025
When I first became reviews editor at Vaccine, my predecessor Kathy Neuzil very kindly gave me advice that I’ve carried into my role as co-EIC. Last year she received the Jenner Award for her contributions to vaccinology. Kathy’s vaccine research & advocacy saved many lives. This is disgraceful.
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Edward Nirenberg @enirenberg.bsky.social · 11/04/2025
you now have to reconsider. A majority of people will not accept paying this cost to being wrong- at least, not in any kind of short-term timeframe. Instead, they will opt for belief perseverance to resolve their cognitive dissonance.
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@IM_Crit_ @imcrit.bsky.social · 10/04/2025
Refresher on Swan-Ganz catheter:
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Timothy McBride @mcbridetd.bsky.social · 11/04/2025
U.S. Military Removes Commander of Greenland Base After Vance Visit www.nytimes.com/2025/04/11/w...
nytimes.com
U.S. Military Removes Commander of Greenland Base
Although the military did not say why the colonel had been dismissed, it said it would not tolerate any subversion of President Trump’s agenda.
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Dr Lipid @drlipid.bsky.social · 09/04/2025
Lipidology Teaching: Ever see an LDLc of 1000 mg/dL? Few have ever heard of Lipoprotein-X. A pathology that mimics but is not FH. What you need to know. If seen, check for hepatobiliary disease. @nationallipid.bsky.social @aspcardio.bsky.social @escardio.bsky.social @familyheartfdn.bsky.social
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JACC Journals @jaccjournals.bsky.social · 09/04/2025
ICYMI from #ACC25: Dr. Nuccia Morici & colleagues report the results of ALTSHOCK-2, the largest RCT of IABPs in heart failure-related #CardiogenicShock. They found that early IABP implantation did *not* reduce mortality. www.jacc.org/doi/10.1016/... #HeartFailure #CardioSky #ALTSHOCK2
jacc.org
Early Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial
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JAMA @jama.com · 09/04/2025
Staphylococcus aureus bacteremia has a case fatality rate of 15% to 30% and causes 300 000 deaths per year worldwide. This Review discusses management of S aureus bacteremia. ➡️ ja.ma/3RF8b50 #MedSky
Figure 1.  Pathogenicity and Host Interactions of Staphylococcus aureus
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