The microprotein adipogenin (Adig) is predominantly expressed in adipose tissues. Here, we found that Adig interacts with seipin to form a stable, rigid complex. We present the structure of the seipin...

Variants in the familial hypercholesterolemia gene LDLR—the most important genetic driver of cardiovascular disease—can raise circulating low-density lipoprotein (LDL) cholesterol concentrations and i...

Perturbations in lysosome integrity are tightly linked to neurological disorders and ageing, but the underlying pathogenic mechanisms are incompletely understood. Using an unbiased proteomic approach,...

Job description Company Description MONCYTE Health, established in 2024, is an early-stage Finnish health technology company developing a novel solution that integrates cellular diagnostics with robot...

Unique technology and novel data for personalized and optimal treatment of high cholesterol

Reflecting on our paper “The entities enabling scientific fraud at scale are large, resilient, and growing rapidly”

The TUM Venture Labs, BioLabs and Eli Lilly and Company (Lilly) today launched BioLabs|TUM, a new biotechnology innovation hub.

tential of apoB-containing lipoproteins varies substantially both between and within lipoprotein classes. Recent studies using high-resolution cryo-electron microscopy, crosslinking mass spectrometry,...