iiinova — where your digital self keeps evolving

Sourya Shrestha @souryashrestha.bsky.social · 18/09/2026

New paper estimating the epidemiological impact, costs and cost effectiveness of implementing preventive therapy (3HP) among adult household contacts of TB cases in Chitwan & Pyuthan, Nepal. Collab with researchers at @bnmtnepal.bsky.social @johnshopkinssph.bsky.social doi.org/10.1186/s442...

doi.org

Client Challenge

022

Reposted by Sourya Shrestha

Magdi Jacobs @magdi.bsky.social · 01/04/2025

Some notes about TB prevention, as a former TB patient. TB is a bacterial disease. There is a vaccine, but it has variable efficacy & is not widely used in the U.S.. So, you can't make a "personal choice" (vaccine) to maximally protect yourself against this disease. So what protects you?

9366112

Reposted by Sourya Shrestha

Joshua Weitz @joshuasweitz.bsky.social · 02/05/2025

This new guidance is yet another step closer towards an isolationist, diminished view of American science. Changing rules on the fly wastes time & effort and undermines the pipeline of discovery and innovation. Unacceptable & inexcusable (again): grants.nih.gov/grants/guide...

grants.nih.gov

NOT-OD-25-104: Updated NIH Policy on Foreign Subawards

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated NIH Policy on Foreign Subawards NOT-OD-25-104. NIH

15118

Reposted by Sourya Shrestha

Randall Munroe @xkcd.com · 25/04/2025

PhD Timeline xkcd.com/3081

5865978420440

Reposted by Sourya Shrestha

The Ferrari Lab @theferrarilab.bsky.social · 15/04/2025

This is the People's money. This is my money and your money. We did not give it to one man to dispense as he pleases. It was allocated in good faith under the authority of the People's representatives.

03520

Sourya Shrestha @souryashrestha.bsky.social · 02/04/2025

www.nytimes.com/2025/04/02/o... It may seem like a small outbreak, but this is how it starts. Also, measles infection is thought to wipe out existing immunity in our bodies to other infections, making us more vulnerable to them.

nytimes.com

Opinion | I Study Measles. I’m Terrified We’re Headed for an Epidemic.

The outbreak in Texas could become much, much worse.

010

Reposted by Sourya Shrestha

Krassensteins @krassenstein.bsky.social · 01/04/2025

BREAKING: As Cory Booker goes on to his 23rd hour straight, his livestream on TikTok has been “liked” over 175 million times. Yes 175 MILLION!

612346435683

Sourya Shrestha @souryashrestha.bsky.social · 29/03/2025

Gyanendra Shah fined for littering at least.

000

Reposted by Sourya Shrestha

Edward Nirenberg @enirenberg.bsky.social · 29/03/2025

Peter Marks’s resignation letter. Everyone should read this.

Peter Marks, MD, PhD
Director, Center for Biologics Evaluation and Research U.S. Food and Drug Administration
10903 New Hampshire Avenue
Silver Spring, MD 20903
March 28, 2025
Sara Brenner, MD, MPH
Acting Commissioner of Food and Drugs
U.S. Food and Drug Administration
10903 New Hampshire Avenue
Silver Spring, MD 20903
Dear Dr. Brenner:
It is with a heavy heart that I have decided to resign from FDA and retire from federal service as Director of the Center for Biologics Evaluation and Research effective April 5, 2025. I leave behind a staff of professionals who are undoubtedly the most devoted to protecting and promoting the public health of any group of people that I have encountered during my four decades working in the public and private sectors. I have always done my best to advocate for their well-being and I would ask that you do the same during this very difficult time during which their critical importance to the safety and security of our nation may be underappreciated.
Over the past years I have been involved in enhancing the safety of our nation's blood supply, in advancing the field of cell and gene therapy, and in responding to public health emergencies. In the last of these, during the COVID-19 pandemic I had the privilege of watching the vision that I conceived for Operation Warp Speed in March 2020 in collaboration with Dr. Robert Kadlec become a reality under the leadership of HHS Secretary Azar and President Trump due to the unwavering commitment of public servants at FDA and elsewhere across the government. At FDA, the tireless efforts of staff across the agency resulted in remarkably expediting the development of vaccines against the virus, meeting the standards for quality, safety, and effectiveness expected by the American public. The vaccines undoubtedly markedly reduced morbidity and mortality from COVID-19 in the United States and elsewhere. Many of these same individuals applied learnings from the pandemic during a flawless response helping…

15619332

Reposted by Sourya Shrestha

Atul Gawande @agawande.bsky.social · 26/03/2025

State Dept gave Congress its full list of 5,300+ USAID program terminations. The sweeping cuts for health alone - from global childhood vaccines to surveillance for deadly diseases to malaria work - entail massive loss of life & national security risk. www.nytimes.com/2025/03/26/h...

nytimes.com

U.S. to End Vaccine Funds for Poor Countries but Continue Some H.I.V. and TB Aid (Gift Article)

A 281-page spreadsheet obtained by The Times lists the Trump administration’s plans for thousands of foreign aid programs.

617397

Reposted by Sourya Shrestha

Angie Rasmussen @angierasmussen.bsky.social · 26/03/2025

Yesterday when I talked to @maxkozlov.bsky.social about this, I wondered which of my NIH-funded colleagues would have their grants cut. All of them. Research on pandemic viruses has now ground to a screeching halt in the US. www.nature.com/articles/d41...

nature.com

Exclusive: NIH to cut grants for COVID research, documents reveal

Studies on climate change and South Africa are also on the latest list of grants to be terminated, according to updated documents obtained by Nature.

5162112

Reposted by Sourya Shrestha

The Ferrari Lab @theferrarilab.bsky.social · 26/03/2025

NTY reports that US support for Gavi is to be suspended. The US has supplied upwards of 10-15% of Gavi's total budget. We have expected this since 20 January, but that makes it no less callous and short sighted. Vaccination abroad is both a humanitarian good and in the financial interest of the US

nytimes.com

U.S. to End Vaccine Funds for Poor Countries (Gift Article)

A 281-page spreadsheet obtained by The Times lists the Trump administration’s plans for thousands of foreign aid programs.

1139

Reposted by Sourya Shrestha

Joanne Flynn @joanneflynn19.bsky.social · 26/03/2025

I too have been dismissed from NIAID Board of Scientific Counselors along with 3 other women and a non-white man

1107

Reposted by Sourya Shrestha

Barb McQuade @barbmcquade.bsky.social · 15/03/2025

From interview of Lee Bollinger, 1st Amendment scholar who served as dean of @UMichLaw, president of @UMich, and president of Columbia University. www.chronicle.com/article/were...

7242521111334

Reposted by Sourya Shrestha

Prem Thakker ツ @premthakker.bsky.social · 14/03/2025

Columbia announced mass suspensions, expulsions, and degree revocations the same day it received a letter from the Trump administration telling them to do just that if they wanted to keep getting funding

23708311

Reposted by Sourya Shrestha

Dare Obasanjo @carnage4life.bsky.social · 09/03/2025

The coolest thing I’ve seen today is that a bunch of volunteer public health professionals and developers have restored the CDC website from before January 20th 2025. This differs from an archive in that they want to rebuild the links between pages and replicate the full website.

restoredcdc.org

Centers for Disease Control and Prevention

437326988274

Reposted by Sourya Shrestha

Madhu Pai, MD, PhD @madhupai.bsky.social · 03/03/2025

“University presidents are staying quiet as Trump tries to destroy their institutions. It won't work” @gregggonsalves.bsky.social www.thenation.com/article/soci...

thenation.com

Universities Are Under Attack. Silence Is Not an Option.

University presidents are staying quiet as Trump tries to destroy their institutions. It won't work.

24715

Reposted by Sourya Shrestha

Jeremy Berg @jeremymberg.bsky.social · 02/03/2025

I am not going to call this a Bluetorial, because I do not want to sully that term (which, at least I, find joyful). Let’s call it a Orwellial.

media.tenor.com

a cartoon of homer simpson holding a card

ALT: a cartoon of homer simpson holding a card

13544235

Reposted by Sourya Shrestha

The Kyiv Independent @kyivindependent.com · 01/03/2025

Trump and Vance have repeatedly claimed that Zelensky has not been sufficiently grateful for U.S. support throughout the war. We compiled instances where Zelensky has publicly expressed gratitude to the U.S., its people, and its leadership for being Ukraine’s largest supporter.

youtube.com

Zelensky thanks America for four minutes straight

YouTube video by Kyiv Independent

20336141192

Reposted by Sourya Shrestha

Atul Gawande @agawande.bsky.social · 27/02/2025

Rubio terminated 5800 USAID contracts – more than 90% of its foreign aid programs – in defiance of the courts. Here’s a list of just some of the lifesaving awards that were terminated. Nearly all were Congressionally mandated. They’ve saved millions of lives. 🧵

420112336199

Reposted by Sourya Shrestha

Stand Up for Science! @standupforscience.net · 28/02/2025

SAVE OUR SCIENCE! There's a war on science happening right now, and we're trying to win—for the sake of our families, our friends, and our communities. Want to support #StandUpforScience2025? Show up in DC, locally, call your representatives, or visit www.caaps.co/caapsstandup... ☀️

red background that says SOS - save our science!

524687

Reposted by Sourya Shrestha

Stand Up for Science! @standupforscience.net · 12/02/2025

Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence

289114555402

Reposted by Sourya Shrestha

Emily Wong @emilybethwong.bsky.social · 27/02/2025

“This is absolutely shattering, heartbreaking, and incomprehensible. The termination letters issued by the US state department in the last 24 hours mark the abrupt and devastating end to years — decades — of investment in lifesaving programmes” bhekisisa.org/health-news-...

bhekisisa.org

BREAKING: Trump orders USAID-funded HIV organisations in SA to shut down - Bhekisisa

In today’s newsletter, Mia Malan explains how US President Donald Trump ordered USAID-funded HIV organisations in SA to shut down. Sign up for our newsletter today. THIS IS A BREAKING, DEVELOPING STOR...

43222

Reposted by Sourya Shrestha

Birat Nepal Medical Trust @bnmtnepal.bsky.social · 11/02/2025

On International Day of Women and Girls in Science, we express our heartfelt gratitude to Dr. Bhawana Shrestha of GENETUP for her unwavering dedication to supporting those affected by Tuberculosis. Thank you for your invaluable contributions. You inspire us all. #11February

032

Sourya Shrestha @souryashrestha.bsky.social · 26/02/2025

A new publication describing our recent work in characterizing TB outbreak investigations in the United States and projecting their costs, impact, and cost-effectiveness in collaboration with researchers at @johnshopkinssph.bsky.social DTBE/CDC and CADPH wwwnc.cdc.gov/eid/article/...

wwwnc.cdc.gov

Model-Based Analysis of Impact, Costs, and Cost-Effectiveness of Tuberculosis Outbreak Investigations, United States

Impact of Tuberculosis Outbreak Investigations

141

Reposted by Sourya Shrestha

Carl T. Bergstrom @carlbergstrom.com · 24/02/2025

Not that you needed any more evidence that Musk is an utter buffoon but JFC.

WASHINGTON — Responses to the Elon Musk-directed email to government employees about what work they'd accomplished over the past week are expected to be fed into an artificial intelligence system to determine whether those jobs are necessary or not, according to three sources with knowledge of the system.

The information will go into an LLM (Large Language Model), an advanced AI system that looks at huge amounts of text data to understand, generate, and process human language, the sources said. The AI system will determine whether someone’s work is mission-critical or not.

4138696

Reposted by Sourya Shrestha

Justin Wolfers @justinwolfers.bsky.social · 17/02/2025

One thing I've learned to do when I have questions about social security number holders who are age 100 or older is to look up the SSA Inspector General audit report, "Numberholders Age 100 or Older Who Did Not Have Death Information on the Numident." t.co/AdWTV8eIPV

t.co

https://oig.ssa.gov/assets/uploads/a-06-21-51022.pdf

21880219

Reposted by Sourya Shrestha

Kyle Griffin @kylegriffin1.bsky.social · 17/02/2025

BREAKING WAPO: Elon Musk's DOGE is seeking access to a heavily-guarded IRS system that includes detailed financial information about every taxpayer, business, and nonprofit in the country — sparking alarm within the tax agency. www.washingtonpost.com/business/202...

washingtonpost.com

Musk’s DOGE seeks access to personal taxpayer data, raising alarm at IRS

Musk’s DOGE seeks access to personal taxpayer data at IRS

28540621839

Reposted by Sourya Shrestha

John Green @johngreensbluesky.bsky.social · 07/02/2025

Just received this photo from a friend of a warehouse in Kinshasa. These are tuberculosis medications--ALREADY PAID FOR--that aren't being distributed due to the Trump Administration's stop work order. TB treatment is being interrupted in SO many patients around the world. What does that mean? (1/2)

Photograph of a warehouse in Kinshasa where unboxed tuberculosis medications are going undistributed due to the stop work order by the Trump Administration.

15971242969

Reposted by Sourya Shrestha

Gregg Gonsalves @gregggonsalves.bsky.social · 15/02/2025

There will be nothing left of biomedical research in the US when Trump is done. Just think about that and anytime you or someone you love has been sick or dying. www.science.org/content/arti...

science.org

‘Wrecking ball’: RFK Jr. moves to fire thousands of health agency employees

Supervisors deliver bad news across NIH, CDC

14335156

Reposted by Sourya Shrestha

Dr. Tom Frieden @drtomfrieden.bsky.social · 14/02/2025

Epidemic intelligence service officers are the cream of the cream. They're top doctors, veterinarians & other health professionals. They sign up for a two-year training program to serve the country. Not only is terminating them bad for the country, it's also a disgraceful violation of a commitment.

230293

Sourya Shrestha @souryashrestha.bsky.social · 13/02/2025

Another pandemic maybe brewing. This is exactly when we need a strong and competent government, that is able to coordinate and work with local public health bodies, to work with media to communicate information in a transparent and timely manner, to work with scientists to be better prepared.

000

Reposted by Sourya Shrestha

MIDAS Network @midas-network.bsky.social · 11/02/2025

Ecology and Evolution of Infectious Diseases Conference 2025. The call for abstracts is now open for the EEID 2025 conference at sites.nd.edu/eeid2025 with a submission deadline of March 17. The conference is June 16-19 at the University of Notre Dame.

001