Kidney tubular secretion is an important non-glomerular kidney function and is critical for excretion of toxins and many medications.1,2 Creatinine is freely filtered by the glomerulus and actively se...

Through practical discussions, expert insights, and real-world strategies, participants discuss best practices for keeping up-to-date and translating new information through practical discussions, exp...

The current diagnostic threshold for chronic kidney disease (CKD; estimated glomerular filtration rate [GFR; eGFR] < 60 ml/min per 1.73 m2) may lead to overdiagnosis in older adults. Additionally, no ...

Are you a curious, motivated nephrology fellow or early‑career faculty member with a passion for science communication? NephJC is inviting a small group of talented individuals to join our Editorial I...

One platform for interactive learning, engagement and collaborative knowledge

2026 multisociety guideline for dyslipidemia — lipid management, cholesterol lowering, ASCVD risk reduction, and treatment pathways.

This week, we will discuss 2026 KDIGO anemia management in patients with kidney disease

Anemia remains a central challenge in chronic kidney disease, influencing quality of life, cardiovascular risk, and clinical outcomes. The updated KDIGO 2026 guideline provides practical recommendatio...

Opportunistic computed tomography (CT)-based screening is the practice of exploiting incidental imaging data for prevention, risk profiling, or presymptomatic detection of relevant disease unrelated…

This cross-sectional study assesses the potential impact of a smartwatch hypertension notification feature for US adults who have not been diagnosed with hypertension.

This week, we aim for an INFINITe allograft lifespan. or flozination in kidney transplant.

PISCES showed a striking cardiovascular benefit with fish oil in hemodialysis. Lovaza closely matches the trial’s ethyl-ester formulation, is FDA regulated, EHR friendly, and offers a practical, re…

This week, we will discuss the POTCAST trial. It is a cardiology trial - but potassium belongs to nephrology.

Assessment of glomerular filtration rate (GFR) has progressed through a series of practical trade-offs between physiological accuracy and clinical feasibility. Direct measurement of GFR using exogenou...

2025 was rich in successful stories. Here are the top 10 that impressed our audience.

This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.

In patients with dialysis-dependent acute kidney injury, a conservative dialysis strategy was evaluated in the LIBERATE-D trial. Could less be more? Join the discussion in #NephJC, but first, check ou...

Holy Mackerel! This week we will discuss fish oil use in maintenance hemodialysis patients. Could this be the one thing that bends the curve on CV mortality, or is it just a red herring?

Curious how n-3 PUFAs may cut serious cardiovascular events in dialysis? 🐟 A big signal, a big dose, and a big discussion ahead — don’t miss this #NephJC! Check out the VA made by our master Brian...

IgA nephropathy, the most common primary glomerulopathy worldwide, is a kidney disorder of B-cell origin characterized by mesangial accumulation of IgA-containing immune complexes. In at least 50% ...

This week, we will discuss the phase 3 ORIGIN3 trial of atacicept, an APRIL/BAFF inhibitor for use in IgAN.

ABSTRACTBackground. High glomerular filtration rate (GFR) is generally regarded as beneficial but has been associated with cardiovascular disease (CVD) and

in this edition: Fish Oil, GBD, Flozination meta-analysis, CHW intervention in Hispanic/Latino patients, and much more

in this edition: Atacicept in IgAN; Albuminuria as a surrogate outcome, Renal Remission and additional CONFIDENCE analysis