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Marc Soco

@msocomd.bsky.social
631 followers 461 following 62 posts

🇵🇭 Internist • Nephrologist 📍 Cebu, Philippines ✈️ Balancing clinical work with a passion for travel and photography 💡 #NephJC Intern • #GlomCon Alum ‘23-24 • #NephSIM ‘20-21

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Reposted by Marc Soco
Nephrology Journal Club @nephjc.bsky.social · 28/05/2026
✨Exciting news #NephtSky The new #NephJC editorial interns are here! 📢Give them a follow and make them feel at home 👉 @drbarbateba.bsky.social @ancast13.bsky.social @kiddokidney.bsky.social @andrewdelaat.bsky.social @farahwehbe92.bsky.social 👇👇 www.nephjc.com/news/2025/6/...
nephjc.com
NephJC Internship 2026-2027 — NephJC
Introducing NephJC’s brand new editorial internship class of 2026-2027
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Nephgirlsketches @nephgirlsketch.bsky.social · 11/03/2026
“The kidneys make the stuff of philosophy itself.” ♥️ Thank you @msocomd.bsky.social
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Nephrology Journal Club @nephjc.bsky.social · 25/02/2026
👉Before we start, a few reminders! Are you new to #NephJC ? Not sure what to do or how this works? Here is a quick rundown, an infographic made by Sinead Stoneman
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Nephrology Journal Club @nephjc.bsky.social · 25/02/2026
⏰90 minutes left until #NephJC chat Hemoglobin targets have swung widely: 📈 Normalize Hb → CV harm signal 📉 Conservative targets → persistent symptoms Have we found the sweet spot yet?
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Nephrology Journal Club @nephjc.bsky.social · 25/02/2026
⏰2 hours until #NephJC chat Anemia in CKD has shaped nephrology for decades ESAs, iron, transfusions, now HIF-PHIs But one question remains: 👉 Are we treating anemia optimally or cautiously?
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Nephrology Journal Club @nephjc.bsky.social · 24/02/2026
#NephSky #MedSky 🩸Blood is thicker than water 🌊 Thankfully we thinned out the 2026 KDIGO Anemia Guidelines for you to peruse. Come discuss what's new. Tuesday 2/24/26 at 9pm EST on Bluesky! Summary by @jeyakumarmeyyappan.bsky.social www.nephjc.com/news/kdigo-anemia
nephjc.com
2026 KDIGO Anemia Management Guidelines — NephJC
This week, we will discuss 2026 KDIGO anemia management in patients with kidney disease
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 24/02/2026
Anemia research in CKD has had so much big fraud stories (which we don’t touch in the #NephJC write up) given the $$$ - the Normal Hct shady analysis from Amgen and PIs that @nejm.org allowed and still stays there - the Roxadustat p-hacking that brought down Fibrogen and tainted HIF-PHIs
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Marc Soco @msocomd.bsky.social · 11/02/2026
Marc Soco, nephrologist from the Philippines and flozinator, looking forward to the discussion. No COI #NephJC
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 28/01/2026
nice (and free) review of genetic testing and counselling in renal disease journals.lww.com/kidney360/fu... in @asnpublications.bsky.social #Kidney360 #NephSky #Genetics
Pretest and post-test counseling. (A) The components of pretest counseling. (B) The components of post-test counseling. The goals of the counseling session are depicted in rectangular shapes. Questions that the clinicians should ask themselves are depicted in the white clouds. VUS, variants of uncertain significance.
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Reposted by Marc Soco
Nephrology Journal Club @nephjc.bsky.social · 28/01/2026
In patients with CV disease, the “normal” range may be misleading Mortality is actually higher at K⁺ 3.5–4.0 mmol/L while high-normal levels (4.5–5.0) are associated with lower mortality 👀 #NephJC pubmed.ncbi.nlm.nih....
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Marc Soco @msocomd.bsky.social · 28/01/2026
Hey everyone! Marc here, joining from the Philippines. No COI #NephJC
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Nephrology Journal Club @nephjc.bsky.social · 26/01/2026
🍌🥑Can pushing K⁺ to the high-normal range reduce ICD shocks and hospitalizations? 🎨 #Visualabstract by @jeyakumarmeyyappan.bsky.social ⏰ #NephJC chat on Jan 27, 9 pm EST www.nephjc.com/news/2026/1/...
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Nephrology Journal Club @nephjc.bsky.social · 26/01/2026
¿Elevar el K⁺ al rango alto-normal puede reducir las descargas del DAI y las hospitalizaciones? 🎨Resumen visual por @jeyakumarmeyyappan.bsky.social ✍️Traducido por @dramiliflores.bsky.social www.nephjc.com/news/2026/1/...
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Nephrology Journal Club @nephjc.bsky.social · 26/01/2026
Oh, the weather outside is frightful 🥶🥶 But #NephJC is so delightful, and since you've no place to go #NephSky... Come discuss POTCAST: potassium goals and cardiac arrhythmias 1/27/26 at 9pm EST on #Bluesky Summary by @shelliefravel.bsky.social @salinesolut.bsky.social www.nephjc.com/news/potcast
nephjc.com
POTCAST- K+ Pop and Arrhythmia Drop — NephJC
This week, we will discuss the POTCAST trial. It is a cardiology trial - but potassium belongs to nephrology.
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Nephrology Journal Club @nephjc.bsky.social · 03/01/2026
It's 2026!🎉 We will be counting down the Top Ten Nephrology Stories of 2025 on 1/6/26 at 9 pm EST. Join us on TWITTER (it will always be Twitter to us). Come on by #NephJC faithful for a lively discussion! You picked & we're count'em down. www.nephjc.com/news/2025/1/3/top-stories-in-nephrology-2025
nephjc.com
Top Stories in Nephrology 2025 — NephJC
2025 was rich in successful stories. Here are the top 10 that impressed our audience.
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Nephrology Journal Club @nephjc.bsky.social · 19/12/2025
1/10 Last #NephJC we discussed dialysis frequency in AKI-D #TenPostNephJC We sought to answer an age-old question: Is less is really more? Or less is just simply what it is….less? pubmed.ncbi.nlm.nih.gov/41201895/
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Nephrology Journal Club @nephjc.bsky.social · 17/12/2025
Have you ever “withheld” dialysis because the patient looked good despite questionable labs? Did you feel brave or nervous? 😅 We restrict fluids, potassium, phosphorus… But what about restricting dialysis itself? Let’s talk. #NephJC
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Marc Soco @msocomd.bsky.social · 17/12/2025
Hi everyone ! Marc here from the Philippines 🇵🇭 sharing this “imprisonment” from Jerónimos Monastery in Lisbon 🇵🇹. From historic monasteries to modern trials, let’s LIBERATE-D our thinking. Looking forward to a great discussion! No COI. #NephJC
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Nephrology Journal Club @nephjc.bsky.social · 15/12/2025
Gracias! @dramiliflores.bsky.social #NephSky LIBERATE-D: El Resumen Visual — #NephJC www.nephjc.com/news/2025/12/14/liberate-d-el-resumen-visual
nephjc.com
LIBERATE-D: El Resumen Visual — NephJC
En pacientes con lesión renal aguda en diálisis, se evaluó si una estrategia más conservadora impacta en la recuperación renal. ¿Será que menos es más? Únete a la discusión del ensayo clínico LIBERATE...
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Nephrology Journal Club @nephjc.bsky.social · 17/12/2025
www.nephjc.com/news/... Check out the excellent #NephJC summary by @msocomd.bsky.social and @sejalplakhani.bsky.social
nephjc.com
Dialyze Less, Recover More? AKI’s Chance to Get LIBERATE-D — NephJC
This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.
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Nephrology Journal Club @nephjc.bsky.social · 15/12/2025
Join us for the last #NephJC of 2025, 12/16/25 at 9pm EST!🥳 How soon should we withhold dialysis in AKI? We're discussing the LIBERATE-D trial #NephSky This one might just change your mind 🧠🧠 Blog by @msocomd.bsky.social and @sejalplakhani.bsky.social www.nephjc.com/news/liberated-aki
nephjc.com
Dialyze Less, Recover More? AKI’s Chance to Get LIBERATE-D — NephJC
This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.
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Nephrology Journal Club @nephjc.bsky.social · 01/12/2025
Holy Mackerel! 🐟 🦜Ahoy matey! Could fish oil unlock the mysteries of increased CV mortality in ESRD? 🏴‍☠️ #NephJC Join us for a lively trawling trip 12/2/25 🛥️at 9pm EST Check out the PISCES VA by @brianrifkin.bsky.social www.nephjc.com/news/piscesva
nephjc.com
PISCES: The Visual Abstract — NephJC
Curious how n-3 PUFAs may cut serious cardiovascular events in dialysis? 🐟 A big signal, a big dose, and a big discussion ahead — don’t miss this #NephJC! Check out the VA made by our master Brian...
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Nephrology Journal Club @nephjc.bsky.social · 20/11/2025
1/10 Last #NephJC we discussed the ORIGIN 3 trial which investigated the use of Atacicept in IgAN #TenPostNephJC Read the article 👇 www.nejm.org/doi/10....
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Nephrology Journal Club @nephjc.bsky.social · 19/11/2025
T4d: That’s all partners 🤠 From here until the end of the year we will be catching up on all the late-breaking and simultaneous publications from #KidneyWk 2025. 😮‍💨 Ain’t no party like a #NephJC party!
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Nephrology Journal Club @nephjc.bsky.social · 19/11/2025
T4c: #NephJC The rapid development of treatments for IgAN shows that nephrology can innovate like oncology and cardiology, to the benefit of our patients. Some final words of wisdom from #KidneyWk 2025
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Nephrology Journal Club @nephjc.bsky.social · 19/11/2025
T4a: #NephJC We recently got to hear the patient voice from @jonathanpollack.bsk.social About his journey with IgAN and his excitement for a future of precision medicine while also calling for greater worldwide equity.
nephjc.com
KDIGO IgA Guidelines: A Patient Voice — NephJC
We have a patient perspective on the new IgA Guidelines and what it means to live with IgA in these times.
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Nephrology Journal Club @nephjc.bsky.social · 19/11/2025
T3c: #NephJC The emerging evidence from APRIL/BAFF–axis trials (including VISIONARY (sibeprenlimab) & ORIGIN-3 (atacicept)) highlight how central this pathway is to the mechanisms of IgAN.
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Brian Rifkin @brianrifkin.bsky.social · 19/11/2025
#NephJC
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 19/11/2025
Sorry will remain a dream for a while! We may have network meta-analysis - or will have to wait for them to go generic for an NIH (if NIH will even exist) or some other public funding body to do those trials #NephJC
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 19/11/2025
Same here in 🇨🇦! Related paper: jamanetwork.com/journals/jam... in @jamainternalmed.com Often RCTs include patients in our countries - but the pharma doesn’t bother with getting drugs approved outside the lucrative US market #NephJC
jamanetwork.com
Physical Accessibility of Medicines in Countries Hosting Trials for FDA Approvals
This cross-sectional study aims to determine whether and when medicines receive market authorization in the countries where they are tested for US Food and Drug Administration approval, as well as tre...
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Marc Soco @msocomd.bsky.social · 19/11/2025
Hi everyone, Marc from the Philippines. Exciting times for IgAN… so much happening so fast! And the ASN FOMO is definitely real this year. No COI. #NephJC
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Nephrology Journal Club @nephjc.bsky.social · 19/11/2025
⏰ 2 hours until chat tonight #NephJC editorial team debated for a long time...not whether to discuss @kdigo.org IgAN guidelines, but whether to do it after #Kidneywk...Have we said it well: IgAN guidelines: fresh out of press, already aging gracefully? 👀See it for yourself
nephjc.com
2025 IgAN KDIGO guidelines: fresh out of press, already aging gracefully — NephJC
This week, we will discuss the 2025 KDIGO IgAN guidelines. which the shift from supportive care to structured, evidence-based therapy
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Nephrology Journal Club @nephjc.bsky.social · 18/11/2025
Check out the awesome visual abstract by @salinesolut.bsky.social Attacking the origins of IgAN with atacicept ⚔️ www.nephjc.com/news/2025/11/17/origin-3-the-visual-abstract
nephjc.com
ORIGIN-3: The Visual Abstract — NephJC
Atacicept, BAFF/APRIL inhibition in IgAN
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Nephrology Journal Club @nephjc.bsky.social · 18/11/2025
Resuman Visual Revisa el resumen visual realizado por Clemens Weber @salinesolut.bsky.social . Gracias @dramiliflores.bsky.social ! www.nephjc.com/news/2025/11/17/origin-3-el-resumen-visual
nephjc.com
ORIGIN-3: El Resumen Visual — NephJC
ORIGIN-3 ha llegado a NephJC con atacicept en NIgA. Un paso sólido hacia una terapia dirigida anti BAFF/APRIL, que aborda la fisiopatología desde su origen. ¡Las señales tempranas son prometedoras! R...
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Nephrology Journal Club @nephjc.bsky.social · 18/11/2025
Tonite 11/18/25 on #Bluesky 9pm EST We are discussing ORIGIN3 and atacicept in IgAN. APRIL, BAFF and B-cells, Oh My! (🦁🐯🐻) It's going to be Wicked good. 🧙‍♀️ #NephJC Summary by @notjustdialysis.bsky.social www.nephjc.com/news/atacicept-origin3-gtfb36
nephjc.com
Attacking the Origin of IgAN: ORIGIN3 and Atacicept — NephJC
This week, we will discuss the phase 3 ORIGIN3 trial of atacicept, an APRIL/BAFF inhibitor for use in IgAN.
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 29/10/2025
We had a lot of discussion with Barratt at his rounds on this. His point is that - early diagnosis/identification early in disease process will be key - we do have specific treatment options available now (or will soon have) - just RASi and Flozins without biopsy just masks the issue #NephJC
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Nephrology Journal Club @nephjc.bsky.social · 29/10/2025
🎨Beautiful visual abstract by Dr Natalia Nombera @roxnonna23.bsky.social #NephJC www.nephjc.com/news/...
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Marc Soco @msocomd.bsky.social · 29/10/2025
Hey everyone, Marc from the Philippines. Looking forward to learning tonight. No COI #NephJC
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Juan Carlos Q Vélez, MD @juancarlosqvelez.bsky.social · 25/10/2025
🔬for the diagnosis of glowmrulonephritis, searching for urinary acanthocytes only using bright field illumination is clearly suboptimal compared to utilizing dark field illumination or phase contrast microscopy. #UrinarySediment #UrineMicroscopy karger.com/gdz/article/...
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Nephrology Journal Club @nephjc.bsky.social · 27/10/2025
⏩ Next #NephJC is on IgA nephropathy @kdigo.org guideline 🎨 Nice visual summary by @roxnonna23.bsky.social www.nephjc.com/news/2025/10...
nephjc.com
KDIGO 2025 IgA guidelines - Visual Abstract — NephJC
KDIGO 2025 is here. IgAN management is evolving with precision risk tools, new therapies, and a stronger focus on kidney protection. Check out the visual abstract created by Natalia Nombera
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 20/10/2025
Obinituzumab aka ‘Obi’ is now FDA approved for lupus nephritis finance.yahoo.com/news/fda-app... #lupus
finance.yahoo.com
FDA Approves Genentech’s Gazyva for the Treatment of Lupus Nephritis
SOUTH SAN FRANCISCO, Calif., October 20, 2025--Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced today that the U.S. Food and Drug Administration (FDA) has approved Gazyva...
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 15/10/2025
No one should I remember being mobbed by dietitians in Argentina who are believers in this costly approach (after #ISNWCN debate) Outdated therapy. Move on and flozinate instead #NephJC
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 15/10/2025
Here’s @kidneyboy.bsky.social take on that study pbfluids.com/2009/02/jour... #NephJC
pbfluids.com
Journal Club: low protein diet
Effect of a very low protein diet on outcome: long-term follow-up.This is the long-term follow-up of the B group from the original MDRD study.Enrollment criteria:Age: 18-70Abnormal Cr 1.2-7 women 1…
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Nephrology Journal Club @nephjc.bsky.social · 15/10/2025
🎨Beautiful visual abstract by @msocomd.bsky.social #NephJC
nephjc.com
Protein supplementation in CKD: The Visual Abstract — NephJC
We like protein, or do we? Low protein, high protein, supplements…what’s a nephrologist to do?
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Nephrology Journal Club @nephjc.bsky.social · 15/10/2025
Check the insightful #NephJC summary by @shelliefravel.bsky.social
nephjc.com
The Protein Pendulum in CKD: supplement or restrict? — NephJC
This week, we will discuss an old dilemma in nephrology. To restrict or supplement the proteins? Premise: advanced CKD and dialysis.
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Marc Soco @msocomd.bsky.social · 15/10/2025
Hi everyone, Marc here. Looking forward to hearing everyone’s insights. No COI. #NephJC
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Nephrology Journal Club @nephjc.bsky.social · 13/10/2025
Check at the VA for our discussion of protein diet strategies by @msocomd.bsky.social. Is restricting protein in CKD and pushing protein in ESRD #TWDFNR? www.nephjc.com/news/2025/10...
nephjc.com
Protein supplementation in CKD: The Visual Abstract — NephJC
We like protein, or do we? Low protein, high protein, supplements…what’s a nephrologist to do?
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Nephrology Journal Club @nephjc.bsky.social · 22/09/2025
It's that time of year again 🍂🍂🍂 The #NephJC Fall pledge drive. Plese give if you are able to support our decades long mission of #FOAMed for all. #NephSky #MedSky www.nephjc.com/news/2025/9/22/nephjc-fall-pledge-drive
nephjc.com
NephJC 2025 Fall Pledge Drive — NephJC
Help keep NephJC a vital, original, and unbiased source of medical education.
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Nephrology Journal Club @nephjc.bsky.social · 21/09/2025
1/10 Welcome to #TenPostNephJC Last #NephJC we discussed about AHA/ACC 2025 Hypertension guidelines: PREVENT, Detect, Treat Didn’t catch the pulse of this one? No worries we’ll help you pressure check the 2025 AHA Hypertension Guidelines. ❤ #AHA2025 www.ahajournals.org/doi/10.1161/...
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Josh Waitzman @jwaitz.bsky.social · 17/09/2025
Right: more aldo, more combo meds, advocating for GLP1 as part of lifestyle change Wrong: 130=/=120, even stronger aldo rec, even stronger GLP1 rec so that insurance will cover it #nephjc
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