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sentanuka.bsky.social

@sentanuka.bsky.social
126 followers 330 following 3 posts

Microbiologist :) Studying bacterial pathogenesis, AMR & antimicrobial development. Research fellow @ Institute for Molecular Bioscience, UQ Previously Postdoc @Dunn School of Pathology, University of Oxford. PhD @The Australian National University

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Science Magazine @science.org · 30/09/2026
In Science, researchers present the Virtual Biotech, an AI system to inform drug-development decisions. By combining diverse biomedical and clinical evidence in a unified platform, the system may help identify therapeutic opportunities that would otherwise be missed. scim.ag/4h0KTnJ
scim.ag
The Virtual Biotech: A multi-agent AI framework for therapeutic discovery and development
Drug development requires evidence integration across biological scales and modalities, but relevant tools are fragmented. We introduce the Virtual Biotech, an organization of artificial intelligence ...
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JAMS Brisbane @brisjams.bsky.social · 04/08/2026
What an incredible JAMS15 Symposium 2026 it was! 🧫🦠 😍 JAMS15 brought together researchers, clinicians, students, and industry partners for a day filled with outstanding science, inspiring discussions, and invaluable networking😎
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Nature Microbiology @natmicrobiol.nature.com · 06/05/2026
Out Now! Technological innovations in microbiology #MicroSky
go.nature.com
Technological innovations in microbiology
Nature Microbiology, Published online: 06 May 2026; doi:10.1038/s41564-026-02364-wThe birth and evolution of microbiology have been driven by technology, but human ingenuity is key to ensuring scientifically meaningful discovery.
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Florian Jug @florianjug.bsky.social · 05/05/2026
It is finally out there in published form. 🎉 #MicroSplit (with an 𝕊) #Microscopy 🔬 #AI 🤖 www.nature.com/articles/s41... And no paywall... so... enjoy the read! 💸 👋 This is where the post could end... but I will have to go on for a bit below... 😉 🧵
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Séamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 11/03/2026
Neat paper from Schwille lab. They demonstrate constriction of synthetic vesicles using important components of the bacterial cell division machinery, FtsZ and FtsN. They induce strong constriction of Z-rings in vesicles just by adding the cytoplasmic domain of FtsN www.nature.com/articles/s41...
nature.com
Optimizing spatial organization of FtsZ rings for large-scale constriction in synthetic cells - Nature Communications
Spatially regulated membrane constriction is an important milestone in reconstituting minimal cell division. Here the authors engineer a truncated system where the cytosolic domain of FtsN forms large...
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JAMS Brisbane @brisjams.bsky.social · 10/02/2026
🚨 Save the Date | JAMS15 Symposium 🚨 🎉For the first time ever, the JAMS Symposium lands in Brisbane!🎉 📅 31 July 2026 📍 Translational Research Institute (TRI), Brisbane. 🧪 Call for abstracts opening soon — start thinking about what you’d love to present!
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Jerónimo Rodríguez-Beltrán @jerorb.bsky.social · 27/01/2026
New paper out in @pnas.org, and it made the cover! 👁️ We represent plasmids as circles and mutations as dots, resembling an eye, because in this paper we literally 𝑤𝑎𝑡𝑐ℎ plasmids evolve. ‼️Check Paula’s 🧵 and the paper👇 𝗣𝗹𝗮𝘀𝗺𝗶𝗱 𝗺𝘂𝘁𝗮𝘁𝗶𝗼𝗻 𝗿𝗮𝘁𝗲𝘀 𝘀𝗰𝗮𝗹𝗲 𝘄𝗶𝘁𝗵 𝗰𝗼𝗽𝘆 𝗻𝘂𝗺𝗯𝗲𝗿 www.pnas.org/doi/10.1073/...
Cover of PNAS in which we show plasmids as colourful concentric circles, with dots scattered. The image kind of resembles an eye, although it’s visibly a plot.
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JAMS Brisbane @brisjams.bsky.social · 06/01/2026
As we culture our way into another year, we’re incubating big ideas, strong collaborations, and plenty of scientific curiosity. Wishing everyone a happy, healthy, and scientifically successful New Year! 🧪🥂🦠🔬
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JAMS Brisbane @brisjams.bsky.social · 11/12/2025
Serving facts, fun, and a little friendly contamination. 🤩 End-of-year micro trivia = success! 🎉😄 Shout out to our amazing sponsors for the amazing prizes 🤩 @eppendorf_official @illuminainc @agrf_genomics @bmglabtech @nikonaustralia We are so grateful! 🧪 Thank you to everyone for coming🫵🏼😌
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JAMS Brisbane @brisjams.bsky.social · 02/12/2025
📅 Thursday 4 December ⏰ 6:00–7:30 pm 📍 The Burrow, Beer Garden Room, West End 👥 Teams up to 6 | $5 per person 🍟 Registerations include a bowl of chips per team. 🔗Follow the link (events.humanitix.com/brisjams-end...) to sign up.
events.humanitix.com
BrisJAMs End of Year Trivia
Get tickets on Humanitix - BrisJAMs End of Year Trivia. The Burrow, 52 Russell St, West End QLD 4101, Australia. Thursday 4th December 2025. Find event information.
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sentanuka.bsky.social @sentanuka.bsky.social · 13/11/2025
Its been amazing being part of Bris-JAMS :)
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Vivek Mutalik @vivekmutalik.bsky.social · 09/11/2025
#microsky
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Nature Reviews Microbiology @natrevmicro.nature.com · 10/11/2025
New online! Genome sequencing for prevention of health-care-associated bacterial infections
nature.com
Genome sequencing for prevention of health-care-associated bacterial infections
Nature Reviews Microbiology, Published online: 10 November 2025; doi:10.1038/s41579-025-01254-yMicrobial whole-genome sequencing is an important element of health-care-associated infection (HAI) prevention strategies. Focusing on specific high-priority antibiotic-resistant bacterial pathogens, this Review outlines the epidemiology and microbiology of HAIs and discusses the role of whole-genome sequencing in HAI prevention and surveillance.
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eLife @elife.bsky.social · 10/11/2025
The pathogenic bacteria Shigella avoids detection inside host cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens. Read more in the eLife Insight Article: buff.ly/1mIc6m0
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JAMS Brisbane @brisjams.bsky.social · 27/10/2025
🚀 Thinking about life beyond academia? Join BrisJAMS and Australian Society of Microbiology Qld Branch, this November for an inspiring evening of stories, insights, and real-world advice from scientists who’ve successfully built careers outside the academic path!🌟 6 November 2025, 6:00 PM – 8:00 PM
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Serge Mostowy @sergemostowylab.bsky.social · 13/10/2025
Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei @sydneylmiles.bsky.social @katholt.bsky.social 🙏to transformative collaborative effort www.nature.com/articles/s41...
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JAMS Brisbane @brisjams.bsky.social · 04/09/2025
Thank you everyone for attending last night's BrisJAMS session and our three wonderful speakers for sharing valuable insights into their research. 🔬💡🧫🙌 😎 😁 #MicrobiologyForAll #BacterialInfections #ViralPhylogeny #AntibioticDevelopment #Biofilms #Microbiology2025 #jamsbrisbane
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Vaughn Cooper @vscooper.micropopbio.org · 27/08/2025
The 2024 rankings of bacterial threats
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JAMS Brisbane @brisjams.bsky.social · 25/08/2025
Hello BrisJAMS Community 😎 BrisJAMS returns this September with some scintilating talks featuring three fantastic speakers. 📅 Wednesday, 3 September 2025 🕕 6:00–7:30 PM 📍 The Burrow, West End This free event is open to all in microbiology: students, researchers, and industry pros alike.
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Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 20/07/2025
Superbugs could kill millions more and cost $2tn a year by 2050, models show www.theguardian.com/society/2025...
theguardian.com
Superbugs could kill millions more and cost $2tn a year by 2050, models show
Exclusive: Research on burden of antibiotic resistance for 122 countries predicts dire economic and health outcomes
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JAMS Brisbane @brisjams.bsky.social · 21/07/2025
Dont forget to join us for our Antimirobial resistance special JAMS session this Wednesday, 23rd July (6-7.30 pm)😎
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JAMS Brisbane @brisjams.bsky.social · 07/07/2025
Hello BrisJAMS Community :) BrisJAMS returns this July with an Antimicrobial Resistance Special featuring three fantastic speakers. 📅 Wednesday, 23 July 2025 🕕 6:00–7:30 PM 📍 The Burrow, West End 🍽 Free food provided! This free event is open to all in the microbiology community.
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JAMS Brisbane @brisjams.bsky.social · 07/07/2025
1. Prof. Greg Cook (QUT) The role of efflux pumps in multi-drug-resistant Mycobacterium tuberculosis. 2. Michelle Novais de Paula (UQ) Breaking bacterial resistance with synergistic combinations. 3. Dr. Jiarui Sun (UQ) Antimicrobial resistance genes in pristine Antarctic soils.
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Eric Topol @erictopol.bsky.social · 23/06/2025
This is wild! Engineering E. coli bacteria to turn plastic waste into paracetamol (Tylenol) www.nature.com/articles/s41... www.nature.com/articles/s41...
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JAMS Brisbane @brisjams.bsky.social · 17/06/2025
Don’t forget to sign up for the PacBio & AGRF special free event this Wednesday at 6 PM! We sure can do a lot at a good old pub! 😎 So join us this time for some scintillating microbiology talks at Burrow, Beer Garden Room, Brisbane 👩‍🔬👨‍🔬🧬🧪🧫🔬🎤
Don’t forget to sign up for the PacBio & AGRF special free event this Wednesday at 6 PM!

We sure can do a lot at a good old pub! 😎
So join us this time for some scintillating microbiology talks at Burrow, Beer Garden Room, Brisbane 👩‍🔬👨‍🔬🧬🧪🧫🔬🎤
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emcra-imb.bsky.social @emcra-imb.bsky.social · 11/06/2025
Introducing 2025 EMCRA Committee Member - Dr. Tanuka Sen! 😀 What is your role in EMCRA? EMCRA Retreat Coordinator 🧘‍♀️
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emcra-imb.bsky.social @emcra-imb.bsky.social · 11/06/2025
🤪 Any fun fact you would like to share with us? I love exploring new restaurants🍽️ & cafes ☕️ and secretly rating them as a professional food critic💯 :P 😋 What is your favourite food? Chicken Biryani 🥘 🧐 Favourite quote? "Set your heart upon your work but never its reward" ❤️💼
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JAMS Brisbane @brisjams.bsky.social · 30/05/2025
🎤 Featured Talks & Speakers: 🔹 Dr. Axayacatl Gonzalez Senior Bioprocess Engineer – IDEA bio, The University of Queensland. Talk Title: Building Communities: A Synthetic Biology Approach to Assemble Robust Microbial Communities to Restore Soil Health and Productivity
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Institut Pasteur | 130 years of biomedical research @pasteur.fr · 26/05/2025
Zoom into a human cell infected by Shigella, the bacteria behind dysentery. Using cryo-EM, @leaswistak.bsky.social and team revealed how it pierces cells with molecular syringes. Stunning science at the nanoscale. @enningalab.bsky.social @jytinevez.bsky.social @nanoimaging.bsky.social #CryoEM
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PLOS Biology @plosbiology.org · 19/05/2025
Bacterial biofilms are important for disease development. This study develops imaging tech to probe spatiotemporal patterns of #Vibrio cholerae #biofilm gene expression, showing that temporal & spatial patterns are established by QS & c-di-GMP, respectively @plosbiology.org 🧪 plos.io/3Fga1GX
Representative images showing DAPI, and rbmA, rbmC, bap1, and vpsR smFISH fluorescence signals and heatmaps of per-cell-volume fluorescence signal as a function of x, y position for n = 5 replicate WT V. cholerae biofilms with the largest biovolumes. Scale bars represent 5 µm.
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Séamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 09/05/2025
I forgot to post about this recent paper - exciting work led by @michriscopy.bsky.social showing clearest evidence yet for transertion strongly tethering the bacterial nucleoid to the membrane during fast growth. It was a pleasure to contribute a little 🔬🦠🧫 www.nature.com/articles/s41...
nature.com
The nucleoid of rapidly growing Escherichia coli localizes close to the inner membrane and is organized by transcription, translation, and cell geometry - Nature Communications
The mechanisms underlying bacterial chromosome configuration are not fully understood. Here, Spahn et al. show that the Escherichia coli nucleoid adopts a condensed, membrane-proximal configuration du...
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Felix Randow @felixrandow.bsky.social · 09/04/2025
RNF213, a host E3 ligase, ubiquitylates LPS to mark cytosol-invading bacteria for autophagy. But how do cytosol-adapted bacteria escape? We found that Shigella's E3 ligase IpaH1.4 blocks LPS ubiquitylation by degrading RNF213 via the proteasome. www.nature.com/articles/s41...
nature.com
Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213 - Nature Structural & Molecular Biology
Naydenova, Boyle and Pathe et al. report that Shigella uses the ubiquitin E3 ligase IpaH1.4 to evade lipopolysaccharide ubiquitylation in infected cells by degrading the host E3 ligase RNF213. Using c...
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eLife @elife.bsky.social · 27/02/2025
🛠️ ’SICKO’ – presented in January's most-read Tools and Resources paper – lets researchers quantify the C. elegans microbiome: elifesciences.org/articles/102... Learn more about publishing your tool…
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Nature Reviews Microbiology @natrevmicro.nature.com · 20/02/2025
New online! The role of bacterial metabolism in antimicrobial resistance
nature.com
The role of bacterial metabolism in antimicrobial resistance
Nature Reviews Microbiology, Published online: 20 February 2025; doi:10.1038/s41579-025-01155-0In this Review, Ahmad et al. examine how antibiotics influence bacterial metabolism and how metabolism, in turn, affects drug efficacy and the emergence and…
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