iiinova — where your digital self keeps evolving

Reposted by Sydney Miles

Serge Mostowy @sergemostowylab.bsky.social · 13/10/2025

Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei @sydneylmiles.bsky.social @katholt.bsky.social 🙏to transformative collaborative effort www.nature.com/articles/s41...

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Reposted by Sydney Miles

LSHTM AMR Centre @lshtmamrcentre.bsky.social · 07/03/2025

🔊 Empowering women in science means amplifying voices, breaking barriers, and driving change. Ahead of #IWD2025, we celebrate Dr. Sydney Miles, whose career is a testament to perseverance, passion, and the power of representation in science. 🔗 bit.ly/4kwlPVl

bit.ly

Empowering women in science: Sydney’s journey and impact | LSHTM

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Reposted by Sydney Miles

MicrobesNG @microbesng.bsky.social · 18/02/2025

Incredible #MicrobialGenomics research powered by MicrobesNG—highlights from our global community of researchers! 🌍🔬 @sydneylmiles.bsky.social presents 15 complete epidemiologically relevant Shigella sonnei genomes, including critical pINV invasion plasmid www.biorxiv.org/content/10.1... #MicroSky

biorxiv.org

A public resource of 15 genomically characterised representative strains of Shigella sonnei

Shigella sonnei is rapidly emerging as the dominant agent of shigellosis, an enteric disease responsible for a significant burden of morbidity and mortality worldwide. Whole-genome sequencing of S. so...

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Reposted by Sydney Miles

VinTorraca @vintorraca.bsky.social · 18/02/2025

There are still a couple of days to apply for this PhD project. A fantastic KCL-A*STAR partnership to study bacterial persistent infections! @vintorraca.bsky.social @oehlerslab.org Project 4.1 of the project catalogue, page 10 Deadline to apply: 23rd February!

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Sydney Miles @sydneylmiles.bsky.social · 06/02/2025

As promised, part 2 here! 🐟 We found that isolates from the dominant lineage 3 of Shigella sonnei carry fewer genes encoding adhesins and fimbriae, but virulence-associated regions remain highly conserved - pointing towards immune evasion and host restriction

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Reposted by Sydney Miles

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 06/02/2025

Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei www.biorxiv.org/content/10.1101/202…

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Sydney Miles @sydneylmiles.bsky.social · 04/02/2025

Most Shigella sonnei experimental work relies on a 70yr old lab strain that doesn’t reflect those circulating today - we are excited to share a (soon to be) publicly available set of genomes and isolates to fill that gap! An exciting part 2 featuring our favourite fish to follow very shortly… 🐟

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Reposted by Sydney Miles

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 04/02/2025

A public resource of 15 genomically characterised representative strains of Shigella sonnei www.biorxiv.org/content/10.1101/202…

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Reposted by Sydney Miles

Stefan Oehlers @oehlerslab.org · 23/01/2025

Got anyone that you would want to banish to rainy London then sweltering Singapore with a risk of giving themselves a shigella infection? Exchange program PhD Project with me and Vincenzo Torraca on page 10 #zebrafish at @astar-idlabs.bsky.social www.kcl.ac.uk/study-legacy...

kcl.ac.uk

Joint A*STAR - King’s College London PhD Studentships in Biomedical Science 2025/26

King's College London is seeking outstanding and motivated students to join our university and the Agency for Science, Technology and Research (A*STAR).

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Reposted by Sydney Miles

VinTorraca @vintorraca.bsky.social · 23/01/2025

Great opportunity for prospective PhD students! Join my lab at KCL and Stefan Oehlers lab at A*STAR to help us dissect how certain bacteria establish infections that are difficult to eradicate in vivo! Project 4.1 of the project catalogue, page 10 Deadline to apply: 23rd February!

kcl.ac.uk

Joint A*STAR - King’s College London PhD Studentships in Biomedical Science 2025/26

King's College London is seeking outstanding and motivated students to join our university and the Agency for Science, Technology and Research (A*STAR).

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Reposted by Sydney Miles

Kate Baker @ksbakes.bsky.social · 19/12/2024

Certain sublineages of antimicrobial resistant bacteria dominate the surveillance landscape, but what causes them to become resistant? Check out our latest work in Shigella to find out and/or read the thread below www.medrxiv.org/content/10.1101/2024.10.27.24316207v2 1/n

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Zebrafish Rock! @zebrafishrock.bsky.social · 05/12/2024

Woohoo! Congrats, Dr. Miles 🎉 #PhDone

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Sydney Miles @sydneylmiles.bsky.social · 05/12/2024

What better occasion to mark my first Bluesky post than passing my PhD viva?! 🎓 A huge huge thank you to my supervisors @sergemostowylab.bsky.social and @katholt.bsky.social and of course the examiners @jayhinton.bsky.social and Lucy Weinert for making the defense a great experience!

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Reposted by Sydney Miles

Melanie Blokesch @mblokesch.bsky.social · 25/11/2024

Exciting times! Our latest preprint is now live 🤩! After nearly 16 yrs of running my lab, I truly believe this is one of the most significant contributions we've made. It offers fresh hypotheses about how pandemic Vibrio cholerae spreads globally. Let’s dive in!🧵..1/n www.biorxiv.org/content/10.1...

biorxiv.org

Diverse phage defence systems define West African South American pandemic Vibrio cholerae

Our understanding of the factors underlying the evolutionary success of different lineages of pandemic Vibrio cholerae remains incomplete. Interestingly, two unique genetic signatures define the West ...

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Reposted by Sydney Miles

Phil Elks @elkslab.bsky.social · 19/11/2024

An exciting PhD opportunity in a great collaboration between @noelresearchlab.bsky.social and my lab looking at heart infections in zebrafish. Details below. Deadline is the 13th December. www.findaphd.com/phds/project...

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