Abstract. Pleiotropy, the phenomenon where a single mutation influences multiple phenotypic traits, creates genetic correlations that can constrain evoluti

Tree-ring evidence shows how grassland decline set off smallpox that ultimately ended the last nomadic empire.

Kazakhstan Releases First Tiger Into Wild in More Than 70 Years

Adaptive potential determines how populations respond to environmental change. This study compiles evolvability estimates from over 170 multicellular species, revealing substantial variation across th...

Abstract. Seasonal migratory animals can evolve residency through adaptation. The threshold model of quantitative genetics predicts that residency evolves

Abstract. Natural selection encodes learned information in the genome. Learned solutions may be tuned specifically to past challenges, failing in altered e

Abstract. In 2006, a manuscript appeared with a provocative title: “Darwinian evolution can follow only very few mutational paths to fitter proteins.” Twen

We investigated what factor contributes to a cline of a chromosomal inversion of the Eurasian blackcap, which differs from typical inversion clines maintained by divergent selection. Using a simulati...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

evol-mut-circle is an international group of scientists, philosophers, and historians interested in research on the role of mutation in evolution, particularly as a dispositional factor. The group …

In dieser Podcast-Episode erklärt die Evolutionsbiologin Dr. Barbara Fischer die spannende Herausforderung der menschlichen Geburt: das Verhältnis von Kopfgröße Neugeborener zum mütterlichen Becken. O...

Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

Nature Reviews Genetics - In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without...

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Abstract. Understanding how biological sequences give rise to observable traits, that is, how genotype maps to phenotype, is a central goal in biology. Yet

The Department of Systems Analysis, Integrated Assessment and Modelling (SIAM) has an opening for a

Summary: Unlike chill-sensitive Drosophila that lose muscle membrane polarization in the cold, chill-tolerant species can maintain polarization via preservation of Na+/K+-ATPase-driven electrogenesis,...

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Abstract. Genetic covariance matrices (G-matrices) are a key focus for research and predictions from quantitative genetic evolutionary models of multiple t

Epigenetic landscapes were proposed by Waddington as the central concept to describe cell fate dynamics in a locally low-dimensional space. In mode...