Reposted by Haoran Cai
As simulations grow in complexity, a set of non-trivial issues emerge: diminished identifiability as free parameters become too numerous relative to exp. constraints & difficulties grasping causality. In our new 📄, we point to potential avenues to move #CellBio forward 👇 arxiv.org/abs/2608.06998
arxiv.org
Simulating is not always understanding: When model complexity obscures biology
In cell biology, computational models of biological systems range from minimal representations with a handful of parameters to whole-cell simulations tracking thousands of molecular species across a c...